Pollen and macrofossil profiles from six cores in Illinois, U.S.A

Pollen analysis of Wisconsinan sediments from eleven localities in northern and central Illinois, combined with the results of older studies, allows a first general survey of the vegetational changes in Illinois during the last glaciation. In the late Altonian (after 40,000 B.P.), pine was already the most prevalent tree type in northern Illinois. Probably because of the influence of the last Altonian ice advance to northern Illinois, pine migrated to the south and reached south-central Illinois, which was at that time a region of prairie, with oak and hickory trees in favorable sites. Likewise in the late Altonian, spruce appeared in northern Illinois. Spruce also expanded its area to the south during the Wisconsinan, reaching south-central Illinois only after 21,000 B.P., in the early Woodfordian. Deciduous trees (predominantly oak) were present in south-central Illinois throughout the Wisconsinan. Their prevalence decreased to the north. The vegetation during the different subdivisions of the last glacial period in Illinois was approximately as follows: Late Altonian: Pine/spruce forest with some deciduous trees in northern and central Illinois; prairie and oak/hickory stands in south-central Illinois; immigration of pine. Farmdalian: Pine/spruce forest in central Illinois; deciduous trees and pine in south-central Illinois, with areas of open vegetation, perhaps similar to the present-day transition of prairie to forest in the northern Great Plains. Woodfordian: Northern and central Illinois ice covered; in south central Illinois, spruce and oak as dominant tree types, but also pine and grassland. During the Woodfordian, pine and spruce disappeared again from south-central Illinois, and oak/hickory forest and prairie again prevailed. The ice-free areas of northern Illinois become populated temporarily with spruce, but later there is proof of deciduous forest in this region. Pollen investigations in south-central Illinois have shown convincingly that deciduous trees could survive relatively close (less than 60 km) to the ice margin. Therefore the frequently presented view that arctic climatic conditions prevailed in North America during the last glaciation far south of the ice margin can be refuted for the Illinois area, confirming the opinion of other authors resulting from investigations of fossil mollusks and frost-soil features. The small number of localities investigated still permits no complete reconstruction of the vegetation zones and their possible movements in Illinois. During the Altonian and Farmdalian in Illinois, a vegetational zonation probably existed similar to that of today in North America. As the ice pushed southward as far as 39° 20' N. lat in the early Woodfordian, this zonation was apparently broken up under the influence of a relatively moderate climate. In any case, the Vandalia area, which was only about 60 km south of the ice, was at that time neither in a tundra zone nor in a zone of boreal coniferous forest.

Pollen record from Eifel maar

A new interglacial pollen sequence from the Döttinger dry maar in the Eifel region of the Rheinish Schield is presented. Palynology is used to correlated to several classical north German Holsteinian sites. The lake sediments reveal the complete interglacial and also 60 m of laminated sediments from the glacial preceding the Holsteinian. The interglacial section indicates limnic conditions in its lower part and telmatic conditions in its upper part with an intermediate episode of peat formation. Ash layers document internsive volcansim during the interglacial in the Eifel region. Some of the north German Holsteinian sites reval spikes of high abundance of Pinus, Beutal and Poaceae and/or setbacks of more demanding taxa during the interglacial, often interpreted as cold events. The Döttingen profile shows similar pattern, but with little response from the thermophilous pollen taxa. In the Döttingen sequence these vegetation 'anomalies' are preceded, or accompanied by phases of active volcanism. The role/interaction of climate and/or volcanism as a likely cause for these vegetation 'anomalies' ist still to be quantified.

Pollen flux off Cape Blanc

Fluxes of airborne freshwater diatoms (FD), phytoliths (PH), and pollen grains (PO) collected with sediment traps off Cape Blanc, northwest Africa, from 1988 till 1991 are presented. Both continental rainfall variations and wind mean strength and direction play a key role in the temporal fluctuations of the fluxes of eolian traces in the pelagic realm. Drier conditions in Northern Africa in 1987 could have preceded the high lithogenic input and moderate FD flux in 1988. The PH peak in summer 1988 was probably caused by increased wind velocity. Wetter rainy seasons of 1988/89 might have promoted a significant pollen production in summer 1989, and FD in late 1989 and early 1990, as well as contributed to the reduction of the lithogenic flux in 1989/90. Decreased fluxes of FD, PH and PO, and higher contribution of the 6-11 µm lithogenic fraction in 1991 would mainly reflect minor intensity and decreased amount of continental trade winds. Air-mass backward trajectories confirm that the Saharan Air Layer is predominantly involved in the spring/summer transport. Trade winds play a decisive role in the fall/winter months, but also contribute to the transport during late spring/summer. Origin of wind trajectories does not support a direct relationship between transporting wind-layers and material source areas in Northern Africa. High winter fluxes of eolian tracers and high amount of trade winds with continental origin in summer warn against a simplistic interpretation of the seasonal eolian signal preserved in the sediments off Cape Blanc, and the wind layer involved in its transport.

Pollen records from Bol'shoy Lyakhovsky Island, Siberia

Cryolithological, ground ice and fossil bioindicator (pollen, diatoms, plant macrofossils, rhizopods, insects, mammal bones) records from Bol'shoy Lyakhovsky Island permafrost sequences (73°20'N, 141°30'E) document the environmental history in the region for the past c. 115 kyr. Vegetation similar to modern subarctic tundra communities prevailed during the Eemian/Early Weichselian transition with a climate warmer than the present. Sparse tundra-like vegetation and harsher climate conditions were predominant during the Early Weichselian. The Middle Weichselian deposits contain peat and peaty soil horizons with bioindicators documenting climate amelioration. Although dwarf willows grew in more protected places, tundra and steppe vegetation prevailed. Climate conditions became colder and drier c. 30 kyr BP. No sediments dated between c. 28.5 and 12.05 14C kyr BP were found, which may reflect active erosion during that time. Herb and shrubby vegetation were predominant 11.6-11.3 14C kyr BP. Summer temperatures were c. 4 °C higher than today. Typical arctic environments prevailed around 10.5 14C kyr BP. Shrub alder and dwarf birch tundra were predominant between c. 9 and 7.6 kyr BP. Reconstructed summer temperatures were at least 4 °C higher than present. However, insect remains reflect that steppe-like habitats existed until c. 8 kyr BP. After 7.6 kyr BP, shrubs gradually disappeared and the vegetation cover became similar to that of modern tundra. Pollen and beetles indicate a severe arctic environment c. 3.7 kyr BP. However, Betula nana, absent on the island today, was still present. Together with our previous study on Bol'shoy Lyakhovsky Island covering the period between about 200 and 115 kyr, a comprehensive terrestrial palaeoenvironmental data set from this area in western Beringia is now available for the past two glacial-interglacial cycles.

Pollen records of five sediment cores from northern Germany

Within a larger program research work is being done on the history of settlement and landscape of the 'Siedlungskammer' Flögeln and the adjacent area. The 'Siedlungskammer' consists of an isolated pleistocene sand ground (Geest-island) surroundet by bogs. Starting from the edge of the Geest, near which large-scale archaeological excavations are carried out, three raised bog profiles were taken at 300, 500 and 4000 m off the prehistoric settlement. They were investigated by means of pollen analysis, and reflect in a decreasing way the activities of man on the Geestisland. Another pollen diagram from the nearby fen peat was worked out for comparison. At the same time it helped to date back a prehistoric sand path to the Roman period. The pollen diagrams cover the vegetational history without gaps from the early Atlantic period to modern times. The vegetation was decisively determined by the poor soils of this area. T'he pollen diagrams give evidence of the activity of settlers since the Neolithic age, with some gaps in the beginning, but later continuously from the middle of the Bronze age until the early migration period. The influence of the nearby settlement, which existed from the Birth of Christ to the 4/5th century, comes out distinctly. Among the cereals which were then cultivated here, there also was rye, at least in the 4/5th century, but most probably already during the Roman period. Besides that people cultivated barley, oats, and flax. The settlement break during the so-called dark ages between the 4/5th century and the time about 800 A.D. was confirmed by pollen analysis. During this time the area was once more covered by forests. The fluctuations of man's activities during the late Middle Ages and modern times, as they are made visible by pollen analysis, correspond to historically wellknown developments.

Non-Verbal Categories. Analysis of an Galician Oral Narrative

Based on the concept of the triple basic structure of human communication by Poyatos (1994a, 1994b) and on the analytical and theoretical implications that derive from this, the present paper conceives the human communication as an indivisible whole in which verbal communication can not be separated from body behavior. This paper analyzes nonverbal categories used in oral communication. The corpus consists of an oral narration in Galician from which we highlighted certain kinemes (minimum units of body movement with meaning) by using the model proposed by Bouvet (2001), in order to explain the non-verbal categories with examples taken from said recordings.

Discapacidad y alojamientos turísticos en España

El turismo accesible representa un segmento con gran potencialidad y generador de una ventajacompetitiva para el sector, dado que los beneficiarios de acciones de accesibilidad engloban a colectivos en crecimiento como el de las personas mayores, las familias, personas con capacidades restringidas temporalmente y embarazadas. Su representatividad en el total de la actividad turística española está en incremento continuo, motivado por dos factores principales: la benevolencia climática y la normativa y cobertura social existente. Por todo ello, en esta investigación se busca determinar los principales hábitos y comportamientos de los turistas españoles con discapacidad en relación al alojamiento utilizado en susviajes, así como determinar cuáles son las variables que pueden influir en dicho comportamiento.

Efficacy and safety of patisiran for familial amyloidotic polyneuropathy: a phase II multi-dose study

BACKGROUND: Transthyretin-mediated amyloidosis is an inherited, progressively debilitating disease caused by mutations in the transthyretin gene. This study evaluated the safety, tolerability, pharmacokinetics, and pharmacodynamics of multiple doses of patisiran (ALN-TTR02), a small interfering RNA encapsulated within lipid nanoparticles, in patients with transthyretin-mediated familial amyloid polyneuropathy (FAP).

Impacto da comunicação empresarial na atração dos colaboradores : TalenterTM, um estudo de caso

Dissertação de Mestrado, Ciências Económicas e Empresariais, 12 de Julho de 2016, Universidade dos Açores.

Travel frequency of seniors tourists

Current demand for tourism is characterized by more frequent, shorter trips throughout the year. Such trends may have adverse effects on the hospitality industry but benefit the travel industry. Most current literature assumes that the variables that determine travel participation are identical to those that influence travel frequency, though there is no evidence to support this assumption. Therefore, the current study seeks to identify variables that influence travel frequency among Spanish senior tourists, who represent a key target market for the tourism industry. The results specify that gender, self-perceived economic status, and self-perceived time available variables strongly determine Spanish seniors' travel frequency.

Development of docetaxel and alendronate-loaded chitosan-conjugated polylactide-co-glycolide nanoparticles: In vitro characterization in osteosarcoma cells

Purpose: To develop docetaxel (DTX)- and alendronate (ALN)-loaded, chitosan (CS)-conjugated polylactide- co-glycolide (PLGA) nanoparticles (NPs) to increase therapeutic efficacy in osteosarcoma cells. Methods: Drug-loaded PLGA NPs were prepared by nanoprecipitation and chemically conjugated by the carboxylic group of PLGA to the amine-bearing CS polymer. The nanocarrier was characterized by dynamic light scattering, transmission electron microscopy, scanning electron microscopy, and differential scanning calorimetry as well as by in vitro drug release and cell culture studies. Results: NP size was within the tumour targeting range (~200 nm) with an effective positive charge (20 mV), thus increasing cellular uptake efficiency. Morphological analysis revealed clear spherical particles with uniform dispersion. The NPs exhibited identical sustained release kinetics for both DTX and ALN. CS-conjugated PLGA with dual-drug-loaded (DTX and AL) NPs showed typical time-dependent cellular uptake and also displayed superior cytotoxicity in MG-63 cells compared with blank NPs, which were safe and biocompatible. Conclusion: Combined loading of DTX and ALN in NPs increased the therapeutic efficacy of the formulation for osteosarcoma treatment, thus indicating the potential benefit of a combinatorial drug regimen using nanocarriers for effective treatment of osteosarcoma.

Post-CMOS compatible high-throughput fabrication of AIN-based piezoelectric microcantilevers

A post-complementary metal oxide semiconductor (CMOS) compatible microfabrication process of piezoelectric cantilevers has been developed. The fabrication process is suitable for standard silicon technology and provides low-cost and high-throughput manufacturing. This work reports design, fabrication and characterization of piezoelectric cantilevers based on aluminum nitride (AlN) thin films synthesized at room temperature. The proposed microcantilever system is a sandwich structure composed of chromium (Cr) electrodes and a sputtered AlN film. The key issue for cantilever fabrication is the growth at room temperature of the AlN layer by reactive sputtering, making possible the innovative compatibility of piezoelectric MEMS devices with CMOS circuits already processed. AlN and Cr have been etched by inductively coupled plasma (ICP) dry etching using a BCl3–Cl2–Ar plasma chemistry. As part of the novelty of the post-CMOS micromachining process presented here, a silicon Si (1 0 0) wafer has been used as substrate as well as the sacrificial layer used to release the microcantilevers. In order to achieve this, the Si surface underneath the structure has been wet etched using an HNA (hydrofluoric acid + nitric acid + acetic acid) based solution. X-ray diffraction (XRD) characterization indicated the high crystalline quality of the AlN film. An atomic force microscope (AFM) has been used to determine the Cr electrode surface roughness. The morphology of the fabricated devices has been studied by scanning electron microscope (SEM). The cantilevers have been piezoelectrically actuated and their out-of-plane vibration modes were detected by vibrometry.

Electroreflectance characterization of AlInGaN/GaN high-electron mobility heterostructures

Room temperature electroreflectance (ER) spectroscopy has been used to study the fundamental properties of AlxInyGa${}_{1-x-y}$N/AlN/GaN heterostructures under different applied bias. The (0001)-oriented heterostructures were grown by metal-organic vapor phase epitaxy on sapphire. The band gap energy of the AlxInyGa${}_{1-x-y}{\rm{N}}$ layers has been determined from analysis of the ER spectra using Aspnes' model. The obtained values are in good agreement with a nonlinear band gap interpolation equation proposed earlier. Bias-dependent ER allows one to determine the sheet carrier density of the two-dimensional electron gas and the barrier field strength.

Electro-optical characterization of IC compatible microcantilevers

The aim of this work is to simulate and optically characterize the piezoelectric performance of complementary metal oxide semiconductor (CMOS) compatible microcantilevers based on aluminium nitride (AlN) and manufactured at room temperature. This study should facilitate the integration of piezoelectric micro-electro-mechanical systems (MEMS) such as microcantilevers, in CMOS technology. Besides compatibility with standard integrated circuit manufacturing procedures, low temperature processing also translates into higher throughput and, as a consequence, lower manufacturing costs. Thus, the use of the piezoelectric properties of AlN manufactured by reactive sputtering at room temperature is an important step towards the integration of this type of devices within future CMOS technology standards. To assess the reliability of our fabrication process, we have manufactured arrays of free-standing microcantilever beams of variable dimension and studied their piezoelectric performance. The characterization of the first out-of-plane modes of AlN-actuated piezoelectric microcantilevers has been carried out using two optical techniques: laser Doppler vibrometry (LDV) and white light interferometry (WLI). In order to actuate the cantilevers, a periodic chirp signal in certain frequency ranges was applied between the device electrodes. The nature of the different vibration modes detected has been studied and compared with that obtained by a finite element model based simulation (COMSOL Multiphysics), showing flexural as well as torsional modes. The correspondence between theoretical and experimental data is reasonably good, probing the viability of this high throughput and CMOS compatible fabrication process. To complete the study, X-ray diffraction as well as d33 piezoelectric coefficient measurements were also carried out.