Application of primary allyl amines afforded by the Baylis-Hillman adducts for heterocyclic synthesis: Generation of 5-benzyl-4(3H)-pyrimidinones and 2-benzylidene-2,3-dihydro-pyrrolizin-1-ones

The applications of the primary allyl amines afforded by the acetyl derivative of Baylis-Hillman adducts of acrylate for the synthesis of heterocycles using robust reactions are described. In the first strategy a one-pot synthesis of 5-benzyl-4(3H)-pyrimidinones have been achieved via N-formylation of the amines in the presence of neat formamide followed by ammonium formate-mediated cyclization. These pyrimidinones have been demonstrated to be excellent precursor to the 4-pyridinamine derivatives. In the second strategy the synthesis of 2-benzylidene-2,3-dihydro-pyrrolizin-1-ones have been accomplished via treatment of allyl amine with dimethoxyfuran followed by saponification and PPA-mediated intramolecular cyclization.

Functionalized Adamantane Tectons Used in the Design of Mixed-Ligand Copper(II) 1,2,4-Triazolyl/Carboxylate Metal–Organic Frameworks

Bistriazoles, 1,3-bis(1,2,4-triazol-4-yl)propane (tr2pr) and 1,3-bis(1,2,4-triazol-4-yl)adamantane (tr2ad), were examined in combination with the rigid tetratopic 1,3,5,7-adamantanetetracarboxylic acid (H4-adtc) platform for the construction of neutral heteroleptic copper(II) metal−organic frameworks. Two coordination polymers, [{Cu4(OH)2(H2O)2}{Cu4(OH)2}(tr2pr)2(H-adtc)4]·2H2O (1) and [Cu4(OH)2(tr2ad)2(H-adtc)2(H2O)2]·3H2O (2), were synthesized and structurally characterized. In complexes 1 and 2, the N1,N2-1,2,4-triazolyl (tr) and μ3-OH− groups serve as complementary bridges between adjacent metal centers supporting the tetranuclear dihydroxo clusters. The structure of 1 represents a unique association of two different kinds of centrosymmetrical {Cu4(OH)2} units in a tight 3D framework, while in compound 2, another configuration type of acentric tetranuclear metal clusters is organized in a layered 3,6-hexagonal motif. In both cases, the {Cu4(OH)2} secondary building block and trideprotonated carboxylate H-adtc3− can be viewed as covalently bound six- and three-connected nodes that define the net topology. The tr ligands, showing μ3- or μ4-binding patterns, introduce additional integrating links between the neighboring {Cu4(OH)2} fragments. A variable-temperature magnetic susceptibility study of 2 demonstrates strong antiferromagnetic intracluster coupling (J1 = −109 cm−1 and J2 = −21 cm−1), which combines for the bulk phase with a weak antiferromagnetic intercluster interaction (zj = −2.5 cm−1).

Selective uptake, distribution, and redistribution of Cd-109, Co-57, Zn-65, Ni-63, and Cs-134 via xylem and phloem in the heavy metal hyperaccumulator Solanum nigrum L

The focus of this article was to explore the translocation of Cd-109, Co-57, Zn-65, Ni-63, and Cs-134 via xylem and phloem in the newly found hyperaccumulator Solanum nigrum L. Two experiments with the uptake via the roots and transport of Cd-109, Co-57, and Zn-65 labeled by roots, and the redistribution of Cd-109, Zn-65, Co-57, Ni-63, and Cs-134 using flap label in S. nigrum in a hydroponic culture with a standard nutrient solution were conducted. The results showed that Cd-109 added for 24 h to the nutrient medium of young plants was rapidly taken up, transferred to the shoot, and accumulated in the cotyledons and the oldest leaves but was not efficiently redistributed within the shoot afterward leading to a rather low content in the fruits. In contrast, Co-57 was more slowly taken up and released to the shoot, but afterward, this element was redistributed from older leaves to younger leaves and maturing fruits. Zn-65 was rapidly taken up and transferred to the shoot (mainly to the youngest leaves and not to the cotyledons). Afterward, this radionuclide was redistributed within the shoot to the youngest organs and finally accumulated in the maturing fruits. After flap labeling, all five heavy metals tested (Cd-109, Co-57, Zn-65, Ni-63, Cs-134) were exported from the labeled leaf and redistributed within the plant. The accumulation in the fruits was most pronounced for Ni-63 and Zn-65, while a relatively high percentage of Co-57 was finally found in the roots. Cs-134 was roughly in the middle of them. The transport of Cd-109 differed from that previously reported for wheat or lupin and might be important for the potential of S. nigrum to hyperaccumulate cadmium.

Na 50 Nachlass Arthur Schopenhauer - 'Schopenhauer-Archiv', 109 - Beschreibung der Schwierigkeiten des geplanten Besuchs in Hambnurg

veröffentlicht in: Schopenhauer, Arthur : Arthur Schopenhauers sämtliche Werke - München : Piper - Bd. 14 : Der Briefwechsel Arthur Schopenhauers ; 1 (1799 - 1849), Nr. 45;

Fragm. lat. I 1 - Comes duplex

Trägerband: Inc. oct. 109

Na 1 Nachlass Max Horkheimer, 541 - Korrespondenzen mit Leo Löwenthal (p. VI 16, 1 - 146)

109 Briefe zwischen Leo Löwenthal und Max Horkheimer, 1943; 4 Briefe von der Office War Information (Washington) an Leo Löwenthal, Januar 1943; 1 Brief von J. H. Randall an Leo Löwenthal, 24.11.1942; 1 Brief von Dan Levin an Leo Löwenthal, 10.01.1943;

Na 1 Nachlass Max Horkheimer, 542 - Korrespondenzen mit Leo Löwenthal (p. VI 16, 147 - 341)

109 Briefe zwischen Leo Löwenthal und Max Horkheimer; 1 Brief von den Office of Strategie Services (Washington D.C.) an Leo Löwenthal, 23.10.1943; 2 Briefe von Leo Löwenthal an Frederick Pollock, August 1943; 3 Briefe zwischen Daniel Levison und Leo Löwenthal, August 1943;

Na 1 Nachlass Max Horkheimer, 603 - Habilitationsschrift: "Über Kants Kritik an der Urteilskraft als Bindeglied zwischen theoretischer und praktischer Philosophie"; Kollegheft zu einer Vorlesung von K. Goldstein über Gehirnpsychologie (p. VII 7 - VII 11)

"Über Kants Kritik der Urteilskraft als Bindeglied zwischen theoretischer und praktischer Philosophie", Habilitationsschrift, Typoskript, gebunden, 109 Blatt (GS 2, S. 74-146); Zur Habilitation, "Referat Habilitationsschrift", Typoskript, 2 Blatt (GS 11, S. 76-79); Zur Habilitation, "Lebenslauf", Typoskript, 4 Blatt; "Über Husserls erkenntnistheoretische Fundierung der Wesensschau", Habilitations- Probevortrag, vom 27.02.1925, Manuskript, 1 Heft, 18 Blatt, davon 4 leer, 1 zusätzliches Blatt (GS 11, S. 80-99); Kollegheft zu einer Vorlesung von K. Goldstein über Gehirnpsychologie" eigenhändige Notizen, 1 Heft, 19 Blatt, davon 1 leer; Über Kant, Vorlesungsskript einer Begleitveranstaltung zu einer Vorlesung von Hans Cornelius, enthält auch Notizen zu einer Vorlesung über die Anfänge der bürgerlichen Philosophie, Manuskript, 1 Heft, 11 Blatt, Datierung unklar;

Na 1 Nachlass Max Horkheimer, 619 - Unterlagen zu "Empiriokritizismus", "Neukantianismus", "Phänomenologie" und zur "Lebensphilosophie" (p. VIII 29-VIII 33)

"Einleitung in die Philosophie", Wintersemester 1932/33, eigenhändige Notizen, 1 Heft, 12 Blatt, davon 5 leer, und 8 zusätzliche Blätter; Zwei Aufsätze vor 1933 (enthält: "Über Kants Philosophie", Typoskript mit eigenhändigen Korrekturen, 8 Blatt. Mit 1 Blatt von Theodor W. Adorno an Max Horkheimer, 29.04.1954 (GS 11, S. 202-208; "Nicolai Hartmann", ca 1931, Typoskript mit eigenhändigen Korrekturen, 6 Blatt (GS 2, S. 172-176)); "Zur Emanzipation der Philosophie von der Wissenschaft" (GS 10, S. 334-419). Über Empiriokritizismus (Mach), Neukantianismus (Cohen), Phänomenologie (Husserlm Scheler), Lebensphilosophie (Bergson), nach 1927 - vor 1933; a) Typoskript mit eigenhändigen Korrekturen, gebunden, 114 Blatt, b) Typoskript mit handschriftlichen Korrekturen, 109 Blatt; Über Erkenntnistheorie und Gestalttheorie (GS 11, S. 22-69), Manuskript, in 2 Heften (Heft 1, 96 Blatt; Heft 2, 32 Blatt);

Fragm. lat. I 100 - De consolatione philosophiae (II 8,6 - III 1,3; III 6,5 - 8,3), mit Rand- und Interlinearglossen

Trägerband: Ms. Praed. 109; Vorbesitzer: Dominikanerkloster Frankfurt am Main

Ms.Ff.F.Stoltze 3. 109 - Brief von ... Hasenkamp an Friedrich Stoltze

Im Gefängnis Heilbronn, "Alte Neuigkeiten", Persönliche Nachrichten

(Table 1) Potassium, radiogenic Argon 40 and dated age for DSDP Hole 94-608 sediments

K-Ar dates were obtained for three pillow basalt samples recovered from Site 608 (Samples 608-58-1, 103-109 cm; 608-59-1, 3-7 cm; 608-59-1, 48-53 cm). Reliable K-Ar dates cannot be routinely obtained for deep-sea igneous rocks, because they may be subject to inaccuracies related to seawater alteration (Seidemann, 1977, doi:10.1130/0016-7606(1977)88<1660:EOSAOK>2.0.CO;2) and/or the presence of excess radiogenic 40Ar (Dalrymple and Moore, 1968, doi:10.1126/science.161.3846.1132; Dymond, 1970, doi:10.1130/0016-7606(1970)81[1229:EAISBP]2.0.CO;2). Thus, the possibility that the samples dated in this study were subject to these sources of inaccuracy must be evaluated.