920 resultados para Paper Electrophoresis


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This paper presents the preliminary findings of pH and colour measurements carried out on artworks on paperand on wood that had been treated with a poly(vinyl acetate) (PVAC) based adhesive in the 1980s. In both cases, areas treated with PVAC proved to be less acidic than untreated areas. Contrary to expectations, the conservation treatments have not, as yet, increased acidity levels in the objects under study. Colour measurements of the works on paper showed that those that had been backed with a cotton fabric using a mixture of methylcellulose and PVAC were less yellow than those from the same print run that had not been backed. This finding suggests that the backing somehow prevented the natural degradation of the support. In view of these preliminary results, further research is clearly needed. This study forms part of a broader ongoing project to assess the role of PVAC in the conservation of a range of cultural assets.

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En el artículo se realiza un análisis del campo de la formación del profesorado y del modelo de formación permanente de los últimos tiempos, atendiendo los nuevos elementos que actuaron como fuerzas ocultas e impulsoras de un pensamiento formativo innovador. Se analizan también las condiciones para un cambio en la manera de ver la formación permanente del profesorado que, progresivamente, ha pasado de una visión de producto formativo que el profesorado debía asimilar acríticamente, a otra etapa con visiones diversificadas. A continuación, se profundiza la función asesora y los modelos que esta nueva concepción de la formación exigen. Se necesitan asesores, formadores que de manera colaborativa ayuden a reconstruir la práctica educativa.

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New evidence shows that older adults need more dietary protein than do younger adults to support good health, promote recovery from illness, and maintain functionality. Older people need to make up for age-related changes in protein metabolism, such as high splanchnic extraction and declining anabolic responses to ingested protein. They also need more protein to offset inflammatory and catabolic conditions associated with chronic and acute diseases that occur commonly with aging. With the goal of developing updated, evidence-based recommendations for optimal protein intake by older people, the European Union Geriatric Medicine Society (EUGMS), in cooperation with other scientific organizations, appointed an international study group to review dietary protein needs with aging (PROT-AGE Study Group). To help older people (>65 years) maintain and regain lean body mass and function, the PROT-AGE study group recommends average daily intake at least in the range of 1.0 to 1.2 g protein per kilogram of body weight per day. Both endurance- and resistance-type exercises are recommended at individualized levels that are safe and tolerated, and higher protein intake (ie, ≥1.2 g/kg body weight/d) is advised for those who are exercising and otherwise active. Most older adults who have acute or chronic diseases need even more dietary protein (ie, 1.2-1.5 g/kg body weight/d). Older people with severe kidney disease (ie, estimated GFR <30 mL/min/1.73m(2)), but who are not on dialysis, are an exception to this rule; these individuals may need to limit protein intake. Protein quality, timing of ingestion, and intake of other nutritional supplements may be relevant, but evidence is not yet sufficient to support specific recommendations. Older people are vulnerable to losses in physical function capacity, and such losses predict loss of independence, falls, and even mortality. Thus, future studies aimed at pinpointing optimal protein intake in specific populations of older people need to include measures of physical function.

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L'ensenyament d'una llengua determinada intenta aconseguir que s'aprengui aquesta llengua i saber una llengua pot significar: saber vocabulari (conèixer el significat dels mots), saber descodificar estructures, regles sintàctiques (tenir competència lingüística) i especialment tenir competència comunicativa, concepte que inclou els anteriors i els supera ja que vol dir saber utilitzar la llengua.

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The objective of this research project was to evaluate field application results and determine whether the Earth-Gard mat made from recycled material would successfully control erosion and allow vegetation to establish in ditch bottoms and steep slopes. The research would also help determine how steep a grade in the ditch bottoms can be protected from rill and gully erosion and how steep and long a backslope or foreslope can be protected from sheet and rill erosion by the recycled material and allow establishment of vegetation. The Earth-Gard gave satisfactory performance on areas with limited drainage and gradual slopes. Earth-Gard had a longevity of only six months. It was eroded away when used on areas with greater flow or steeper slopes.

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An increasing number of patients suffering from cardiovascular disease, especially coronary artery disease (CAD), are treated with aspirin and/or clopidogrel for the prevention of major adverse events. Unfortunately, there are no specific, widely accepted recommendations for the perioperative management of patients receiving antiplatelet therapy. Therefore, members of the Perioperative Haemostasis Group of the Society on Thrombosis and Haemostasis Research (GTH), the Perioperative Coagulation Group of the Austrian Society for Anesthesiology, Reanimation and Intensive Care (ÖGARI) and the Working Group Thrombosis of the European Society of Cardiology (ESC) have created this consensus position paper to provide clear recommendations on the perioperative use of anti-platelet agents (specifically with semi-urgent and urgent surgery), strongly supporting a multidisciplinary approach to optimize the treatment of individual patients with coronary artery disease who need major cardiac and non-cardiac surgery. With planned surgery, drug eluting stents (DES) should not be used unless surgery can be delayed for ≥12 months after DES implantation. If surgery cannot be delayed, surgical revascularisation, bare-metal stents or pure balloon angioplasty should be considered. During ongoing antiplatelet therapy, elective surgery should be delayed for the recommended duration of treatment. In patients with semi-urgent surgery, the decision to prematurely stop one or both antiplatelet agents (at least 5 days pre-operatively) has to be taken after multidisciplinary consultation, evaluating the individual thrombotic and bleeding risk. Urgently needed surgery has to take place under full antiplatelet therapy despite the increased bleeding risk. A multidisciplinary approach for optimal antithrombotic and haemostatic patient management is thus mandatory.

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L’aspiració de trobar una eina que pugui ajudar a identifi car els papers atenent les sevescaracterístiques sorgeix a fi nal segle XVIII amb les primeres descripcions de les filigranespapereres i va prenent cos al segle XIX com a ciència auxiliar de la codicologia.Des de les últimes dècades del segle XX, les filigranes han anat adquirint un interès creixententre els restauradors de document gràfi c —com una eina més per a la presa de decisions i pera la valoració del procés de restauració— i entre els documentalistes, historiadors, museòlegsi bibliòfils —per a la datació i autenticació de les obres— i, fins i tot, en investigacionspolicials i jurídiques per aclarir algun fet delictiu. No obstant això, durant aquests 150 anys, l’estudi del paper a través de les filigranes papereres a Espanya no ha experimentat cap avenç significatiu pel que fa als mètodes i procediments seguits per a l’obtenció i gestió deles dades. En l’àmbit europeu, encara que a partir dels anys 90 sorgeixen noves propostesd’estudi, aquestes limiten la investigació a l’anàlisi de la filigrana sense assolir una visió global del plec sortit de la forma.

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This paper presents the preliminary findings of pH and colour measurements carried out on artworks on paperand on wood that had been treated with a poly(vinyl acetate) (PVAC) based adhesive in the 1980s. In both cases, areas treated with PVAC proved to be less acidic than untreated areas. Contrary to expectations, the conservation treatments have not, as yet, increased acidity levels in the objects under study. Colour measurements of the works on paper showed that those that had been backed with a cotton fabric using a mixture of methylcellulose and PVAC were less yellow than those from the same print run that had not been backed. This finding suggests that the backing somehow prevented the natural degradation of the support. In view of these preliminary results, further research is clearly needed. This study forms part of a broader ongoing project to assess the role of PVAC in the conservation of a range of cultural assets.

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There has been relatively little change over recent decades in the methods used in research on self-reported delinquency. Face-to-face interviews and selfadministered interviews in the classroom are still the predominant alternatives envisaged. New methods have been brought into the picture by recent computer technology, the Internet, and an increasing availability of computer equipment and Internet access in schools. In the autumn of 2004, a controlled experiment was conducted with 1,203 students in Lausanne (Switzerland), where "paper-and-pencil" questionnaires were compared with computer-assisted interviews through the Internet. The experiment included a test of two different definitions of the (same) reference period. After the introductory question ("Did you ever..."), students were asked how many times they had done it (or experienced it), if ever, "over the last 12 months" or "since the October 2003 vacation". Few significant differences were found between the results obtained by the two methods and for the two definitions of the reference period, in the answers concerning victimisation, self-reported delinquency, drug use, failure to respond (missing data). Students were found to be more motivated to respond through the Internet, take less time for filling out the questionnaire, and were apparently more confident of privacy, while the school principals were less reluctant to allow classes to be interviewed through the Internet. The Internet method also involves considerable cost reductions, which is a critical advantage if self-reported delinquency surveys are to become a routinely applied method of evaluation, particularly so in countries with limited resources. On balance, the Internet may be instrumental in making research on self-reported delinquency far more feasible in situations where limited resources so far have prevented its implementation.

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Aquest treball estudia els personatges femenins de la filmografia de Yasujiro Ozu durant el període d'ocupació nord-americana a l'estat japonès (1945-1953).

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Capillary electrophoresis has drawn considerable attention in the past few years, particularly in the field of chiral separations because of its high separation efficiency. However, its routine use in therapeutic drug monitoring is hampered by its low sensitivity due to a short optical path. We have developed a capillary zone electrophoresis (CZE) method using 2mM of hydroxypropyl-β-cyclodextrin as a chiral selector, which allows base-to-base separation of the enantiomers of mianserin (MIA), desmethylmianserin (DMIA), and 8-hydroxymianserin (OHMIA). Through the use of an on-column sample concentration step after liquid-liquid extraction from plasma and through the presence of an internal standard, the quantitation limits were found to be 5 ng/mL for each enantiomer of MIA and DMIA and 15 ng/mL for each enantiomer of OHMIA. To our knowledge, this is the first published CE method that allows its use for therapeutic monitoring of antidepressants due to its sensitivity down to the low nanogram range. The variability of the assays, as assessed by the coefficients of variation (CV) measured at two concentrations for each substance, ranged from 2 to 14% for the intraday (eight replicates) and from 5 to 14% for the interday (eight replicates) experiments. The deviations from the theoretical concentrations, which represent the accuracy of the method, were all within 12.5%. A linear response was obtained for all compounds within the range of concentrations used for the calibration curves (10-150 ng/mL for each enantiomer of MIA and DMIA and 20-300 ng/mL for each enantiomer of OHMIA). Good correlations were calculated between [(R) + (S)]-MIA and DMIA concentrations measured in plasma samples of 20 patients by a nonchiral gas chromatography method and CZE, and between the (R)- and (S)-concentrations of MIA and DMIA measured in plasma samples of 37 patients by a previously described chiral high-performance liquid chromatography method and CZE. Finally, no interference was noted from more than 20 other psychotropic drugs. Thus, this method, which is both sensitive and selective, can be routinely used for therapeutic monitoring of the enantiomers of MIA and its metabolites. It could be very useful due to the demonstrated interindividual variability of the stereoselective metabolism of MIA.

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This leaflet talks about the architecture of library buildings. It provides information on the selection of an architect and how to design flooring and room arrangements in a practical way.

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Aquest treball analitza l’enregistrament audiovisual d’una activitat de guiatge duta a terme per una professora practicant en el rol d’investigadora en l’acció en una classe de català de 1r d’ESO per valorar el grau d’efectivitat de la seva parla. Al llarg de la recerca, es confronten els resultats de l’anàlisi qualitativa i quantitativa recollits a partir del discurs enregistrat de la docent amb mostres del treball fet pels alumnes per donar resposta a les preguntes de la investigació i extreure conclusions que permetin configurar una guia de propostes de millora per a la futura tasca docent de la investigadora