Enhanced spectral sensitivity of fibre long period gratings to refractive index of aqueous solutions utilising copper patterned coatings

A set of long period grating devices have been fabricated in photosensitive single mode fibre coated with a series of copper rings (period of 380μm, 50% duty cycle and length of 4cm). The long period gratings were inscribed with a uniform UV-laser exposure across the entire length of the copper ring patterned coating. The devices ranged in copper thickness from 0.5μm to 1.5μm. In addition, a control long period grating was fabricated in the same type of fibre with the same period for comparison. The refractive index and temperature spectral sensitivity of these devices were investigated and it was found that the index and temperature sensitivity is a function of the thickness of the copper rings, as supported by theoretical modelling. Furthermore, the index sensitivity of these devices in the 1.333 index region is greater than the control long period grating. The patterned 0.5μm coated long period grating gave a sensitivity of Δλ/Δn = -74 nm leading to a resolution of 1.4×10-3 compared to the control which had a sensitivity of Δλ/Δn = -32 nm with a resolution of 3.2×10-3 in the index region of 1.320 to 1.380 (aqueous solution regime). This demonstrates a two fold increase in the sensitivity. This novel fibre long period grating device shows potential for increasing the resolution of measurements of the index of aqueous solutions.

Obstacles and solutions to maximising urban biodiversity throughout the lifecycles of major developments in England

Thus far, achieving net biodiversity gains through major urban developments has been neither common nor straightforward - despite the presence of incentives, regulatory contexts, and ubiquitous practical guidance tools. A diverse set of obstructions, occurring within different spatial, temporal and actor hierarchies, are experienced by practitioners and render the realisation of maximised biodiversity, a rarity. This research aims to illuminate why this is so, and what needs to be changed to rectify the situation. To determine meaningful findings and conclusions, capable of assisting applied contexts and accommodating a diverse range of influences, a ‘systems approach’ was adopted. This approach led to the use of a multi-strategy research methodology, to identify the key obstructions and solutions to protecting and enhancing biodiversity - incorporating the following methods: action research, a questionnaire to local government ecologists, interviews and personal communications with leading players, and literature reviews. Nevertheless, ‘case studies’ are the predominant research method, the focus being a ‘nested’ case study looking at strategic issues of the largest regeneration area in Europe ‘the Thames Gateway’, and the largest individual mixeduse mega-development in the UK (at the time of planning consent) ‘Eastern Quarry 2’ - set within the Gateway. A further key case study, focussing on the Central Riverside development in Sheffield, identifies the merits of competition and partnership. The nested cases, theories and findings show that the strategic scale - generally relating to governance and prioritisation - impacts heavily upon individual development sites. It also enables the identification of various processes, mechanisms and issues at play on the individual development sites, which primarily relate to project management, planning processes, skills and transdisciplinary working, innovative urban biodiversity design capabilities, incentives, organisational cultures, and socio-ecological resilience. From these findings a way forward is mapped, spanning aspects from strategic governance to detailed project management.

Matrix-assisted diffusion-ordered spectroscopy:application of surfactant solutions to the resolution of isomer spectra

The component spectra of a mixture of isomers with nearly identical diffusion coefficients cannot normally be distinguished in a standard diffusion-ordered spectroscopy (DOSY) experiment but can often be easily resolved using matrix-assisted DOSY, in which diffusion behaviour is manipulated by the addition of a co-solute such as a surfactant. Relatively little is currently known about the conditions required for such a separation, for example, how the choice between normal and reverse micelles affects separation or how the isomer structures themselves affect the resolution. The aim of this study was to explore the application of sodium dodecyl sulfate (SDS) normal micelles in aqueous solution and sodium 1,4-bis(2-ethylhexyl)sulfosuccinate (AOT) aggregates in chloroform, at a range of concentrations, to the diffusion resolution of some simple model sets of isomers such as monomethoxyphenols and short chain alcohols. It is shown that SDS micelles offer better resolution where these isomers differ in the position of a hydroxyl group, whereas AOT aggregates are more effective for isomers differing in the position of a methyl group. For both the normal SDS micelles and the less well-defined AOT aggregates, differences in the resolution of the isomers can in part be rationalised in terms of differing degrees of hydrophobicity, amphiphilicity and steric effects. Copyright © 2012 John Wiley & Sons, Ltd.

A method of fundamental solutions for transient heat conduction

In this paper we investigate an application of the method of fundamental solutions (MFS) to transient heat conduction. In almost all of the previously proposed MFS for time-dependent heat conduction the fictitious sources are located outside the time-interval of interest. In our case, however, these sources are instead placed outside the space domain of interest in the same manner as is done for stationary heat conduction. A denseness result for this method is discussed and the method is numerically tested showing that accurate numerical results can be obtained. Furthermore, a test example with boundary singularities shows that it is advisable to remove such singularities before applying the MFS.

Supply chain integration:challenges and solutions

Since its introduction by management consultants in the early 1980s, supply chain management (SCM) has been primarily concerned with the integration of processes and activities both within and between organisations. The concept of supply chain integration (SCI) is based on documented evidence that suggests that much of the waste throughout businesses is a consequence of fragmented supply chain configurations. However, there is also evidence to suggest that the achievement of higher levels of intra- and inter-firm integration presents an array of managerial challenges. The need for innovation in all aspects of SCM is widely recognised. Given the pivotal role of the integration paradigm within SCM, any meaningful innovation in this area must focus heavily on this issue. This chapter outlines some of the challenges by exploring the evolving SCM business context. It goes on to relate SCM theory to the widely cited Porter value chain concept. The core of the chapter provides a detailed description of SCI based on a wide variety of literature. It does so with particular reference to the challenges inherent in implementing an integrated business paradigm with a view to identifying a range of possible innovative solutions. The adoption of more integrated supply chain structures raises questions regarding the nature of both internal and external customer/supplier relationships. The effective management of such relationships is, therefore, given particular focus.

Supply chain innovation for competing in highly competitive markets:challenges and solutions

Rapid changes in technological development are forcing businesses to continuously innovate to improve their competitiveness, which is particularly evident in logistics and supply chain management (SCM), where innovation impacts both the strategic and operational levels. Supply Chain Innovation for Competing in Highly Dynamic Markets: Challenges and Solutions investigates the role of innovation in the management of supply chains of today. This book focuses on supply chain integration from both strategic and operational perspectives and the impact of information technology-related innovation in supply chain and logistics service industries. It also analyzes how environmental innovation affects logistical decisions throughout the supply chain and the strategies employed in managing logistics-related environmental impacts. Finally, the book explores theoretical and practical implications of innovation in the management of supply systems.

Real and imaginary parts of the vibrational relaxation of acetonitrile in its electrolyte solutions:new results for the dynamics of solvent molecules

Isotropic scattering Raman spectra of liquid acetonitrile (AN) solutions of LiBF4 and NaI at various temperatures and concentrations have been investigated. For the first time imaginary as well as real parts of the solvent vibrational correlation functions have been extracted from the spectra. Such imaginary parts are currently an important component of modern theories of vibrational relaxation in liquids. This investigation thus provides the first experimental data on imaginary parts of a correlation function in AN solutions. Using the fitting algorithm we recently developed, statistically confident models for the Raman spectra were deduced. The parameters of the band shapes, with an additional correction, of the ν2 AN vibration (CN stretching), together with their confidence intervals are also reported for the first time. It is shown that three distinct species, with lifetimes greater than ∼10−13 s, of the AN molecules can be detected in solutions containing Li+ and Na+. These species are attributed to AN molecules directly solvating cations; the single oriented and polarised molecules interleaving the cation and anion of a Solvent Shared Ion Pair (SShIP); and molecules solvating anions. These last are considered to be equivalent to the next layer of solvent molecules, because the CN end of the molecule is distant from the anion and thus less affected by the ionic charge compared with the anion situation. Calculations showed that at the concentrations employed, 1 and 0.3 M, there were essentially no other solvent molecules remaining that could be considered as bulk solvent. Calculations also showed that the internuclear distance in these solutions supported the proposal that the ionic entity dominating in solution was the SShIP, and other evidence was adduced that confirmed the absence of Contact Ion Pairs at these concentrations. The parameters of the shape of the vibrational correlation functions of all three species are reported. The parameters of intramolecular anharmonic coupling between the potential surfaces in AN and the dynamics of the intermolecular environment fluctuations and intermolecular energy transfer are presented. These results will assist investigations made at higher and lower concentrations, when additional species and interactions with AN molecules will be present.

Challenges and emerging solutions in the development of compressed orally disintegrating tablets

Areas covered: The review discusses the main challenges of ODT manufacturing process and the emerging solutions featured at early drug development stages. The research specifically describes the methods reported for taste masking/assessment and solubilisation of unpalatable and poorly soluble drugs, respectively. Furthermore, this review highlights the techniques used for developing modified-release ODTs, an emerging area in the field. In addition, it also discusses the poor flowability and segregation problems of directly compressed powders. Moreover, the review describes the tests reported in the literature for ODT disintegration time assessment since a universal technique is still non-existent. Expert opinion: The approaches used to overcome the manufacturing challenges often have a bearing on the price of the end product. However, despite the technical and regulatory challenges, ODTs can offer many advantages over the conventional dosage forms if accompanied by suitable adjuvant technologies and in vitro analytical tools. © 2014 Informa UK, Ltd. Introduction: Orally disintegrating tablets (ODTs) provide several advantages over conventional tablets such as suitability for patients with swallowing difficulties and faster onset of action. The manufacture of ODTs by compression/tableting offers a practical and cost-effective strategy over the freeze drying (lyophilisation) method. Nonetheless, the FDA recommends a disintegration time of 30 s and a maximum weight of 500 mg for a tablet to be labelled as an ODT. These requirements, alongside other desirable product properties, have created a number of challenges for the formulator to overcome while developing compressed ODTs.

The Use of Situation Representation when Searching for Solutions in Computer Aided Design Systems

Projects solutions reuse methodology is offered for software development. The main idea consists in connection of the system objective with the situation using the entities which describe the condition of the system in the process of the objective statement. Every situation is associated with one or several design solutions, which can be used at the development. Based on this connection the situation representing language has been created, it lets to express a problem situation using a natural language describe. The similarity measure has been built to compare situations, it is based on the similarity coefficients with adding the absent part weight.

Frontal Solutions: an Information Technology Transfer to Abstract Mathematics

The paper introduces a method for dependencies discovery during human-machine interaction. It is based on an analysis of numerical data sets in knowledge-poor environments. The driven procedures are independent and they interact on a competitive principle. The research focuses on seven of them. The application is in Number Theory.

Specifics in Applying Agile Software Methodologies in Portal Solutions

Agile methodologies are becoming more popular in the software development process nowadays. The iterative development lifecycle, openness to frequent changes, tight cooperation with the client and among the software engineers are turning into more and more effective practices and respond to a higher extend to the current business needs. It is natural to raise the question which methodology is the most suitable for use when starting and managing a project. This depends on many factors—product characteristics, technologies used, client’s and developer’s experience, project type. A systematic analysis of the most common problems appearing when developing a particular type of projects—public portal solutions, is proposed. In the case at hand a very close interaction with various types of end users is observed. This is a prerequisite for permanent changes during the development and support cycles, which makes them ideal candidates for using an agile methodology. We will compare the ways in which each methodology addresses the specific problems arising and will finish with ranking them according to their relevance. This might help the project manager in choosing one or a combination of the methodologies.

Singular Solutions with Exponential Growth for the (3+1)-D Wave Equation

Недю И. Попиванов, Тодор П. Попов, Рудолф Шерер - Разглеждат се четиримерни гранични задачи за нехомогенното вълново уравнение. Те са предложени от М. Протер като многомерни аналози на задачата на Дарбу в равнината. Известно е, че единственото обобщено решение може да има силна степенна особеност само в една гранична точка. Тази сингулярност е изолирана във върха на характеристичния конус и не се разпространява по конуса. Друг аспект на проблема е, че задачата не е фредхолмова, тъй като има безкрайномерно коядро. Предишни резултати сочат, че решението може да има най-много експоненциален ръст, но оставят открит въпроса дали наистина съществуват такива решения. Показваме, че отговора на този въпрос е положителен и строим обобщено решение на задачата на Протер с експоноциална особеност.

Exact Solutions of Nonlocal Boundary Value Problems for One- and Two-Dimensional Heat Equation

Иван Хр. Димовски, Юлиан Ц. Цанков - Предложен е метод за намиране на явни решения на клас двумерни уравнения на топлопроводността с нелокални условия по пространствените променливи. Методът е основан на директно тримерно операционно смятане. Класическата дюамелова конволюция е комбинирана с две некласически конволюции за операторите ∂xx и ∂yy в една тримерна конволюция. Съответното операционно смятане използва мултипликаторни частни. Мултипликаторните частни позволяват да се продължи принципът на Дюамел за пространствените променливи и да се намерят явни решения на разглежданите гранични задачи. Общите разглеждания са приложени в случая на гранични условия от типа на Йонкин. Намерени са експлицитни решения в затворен вид.

Quasi-Regular Solutions for 3D Equations of Tricomi and Keldish Types

Цветан Д. Христов, Недю Ив. Попиванов, Манфред Шнайдер - Изучени са някои тримерни гранични задачи за уравнения от смесен тип. За уравнения от типа на Трикоми те са формулирани от М. Протер през 1952, като тримерни аналози на задачите на Дарбу или Коши–Гурса в равнината. Добре известно е, че новите задачи са некоректни. Ние формулираме нова гранична задача за уравнения от типа на Келдиш и даваме понятие за квазиругулярно решение на тази задача и на eдна от задачите на Протер. Намерени са достатъчни условия за единственост на такива решения.

Singular Solutions of Protter’s Problem for a Class of 3-D Hyperbolic Equations

Недю Иванов Попиванов, Алексей Йорданов Николов - През 1952 г. М. Протър формулира нови гранични задачи за вълновото уравнение, които са тримерни аналози на задачите на Дарбу в равнината. Задачите са разгледани в тримерна област, ограничена от две характеристични конуса и равнина. Сега, след като са минали повече от 50 години, е добре известно, че за безброй гладки функции в дясната страна на уравнението тези задачи нямат класически решения, а обобщеното решение има силна степенна особеност във върха на характеристичния конус, която е изолирана и не се разпространява по конуса. Тук ние разглеждаме трета гранична задача за вълновото уравнение с младши членове и дясна страна във формата на тригонометричен полином. Дадена е по-нова от досега известната априорна оценка за максимално възможната особеност на решенията на тази задача. Оказва се, че при по-общото уравнение с младши членове възможната сингулярност е от същия ред като при чисто вълновото уравнение.