An electronic surveillance and control system for traffic management of the Borman expressway. Final report.

Indiana Department of Transportation, Indianapolis

A study of the effects of sub-sterilization doses of radiation on the storage life extension of soft-shelled clams and haddock fillets : final summary for the period May 1961-May 1962 /

"Contract number AT(30-1)-2329, Task XII and under Contract number AT(30-1)-3006, Task XII."

Tables for the transformation of angular distribution data from the laboratory system to the center of mass system /

"Shell Development Company."

From slave to college president; being the life story of Booker T. Washington,

Mode of access: Internet.

Dynamics of the world climate/food system : a model for prediction of world food production and allocation /

Includes bibliographical references.

Elements of a water quality information system for the State of Illinois /

Cover title.

Storm drainage system improvement plan, Village of Garrett, Illinois, Douglas County, IL : executive summary.

"The Illinois Department of Natural Resources/Office of Water Resources(IDNR/OWR) is cooperating with the Village of Garrett to construct a flood control project under the authority of the Flood Control Act of 1945, 615 ILCS 15 (2004 State Bar Edition)."

Tales of an American landlord; containing sketches of life south of the Potomac ...

Title-page of v. 1 missing.

Making appropriations for military quality of life functions of the Department of Defense, military construction, the Department of Veterans Affairs, and related agencies for the fiscal year ending September 30, 2006, and for other purposes : conference report (to accompany H.R. 2528).

"November 18 (legislative day, November 17), 2005."

The poetical works of Thomas Chatterton, with notices of his life, history of the Rowley controversy, a selection of his letters, and notes critical and explanatory.

Edited by C. B. Willcox.

Atlas of the nervous system, including an epitome of the anatomy, pathology, and treatment,

The plates are accompanied by descriptive letter-press on separate leaves. Some of the plates have also outline diagram.

Structure of circulin B and implications for antimicrobial activity of the cyclotides

The solution structure of one of the first members of the cyclotide family of macrocyclic peptides to be discovered, circulin B has been determined and compared with that of circulin A and related cyclotides. Cyclotides are mini-proteins derived from plants that have the characteristic features of a head-to-tail cyclised peptide backbone and a knotted arrangement of their three disulfide bonds. First discovered because of their uterotonic or anti-HIV activity, they have also been reported to have activity against a range of Gram positive and Gram negative bacteria as well as fungi. The aim of the current study was to develop structure-activity relationships to rationalise this antimicrobial activity. Comparison of cyclotide structures and activities suggests that the presence and location of cationic residues may be a requirement for activity against Gram negative bacteria. Understanding the topological differences associated with the antimicrobial activity of the cyclotides is of significant interest and potentially may be harnessed for pharmaceutical applications.

NF-gamma B - a target in the inflammation of bone destruction

NF-kappaB activation is associatied with the inflammation of bone destruction and certain cancers. The NEMO (NF-kB essential modulator)-binding domain (NBD) protein inhibits the activation of NF-kappaB. Cellular studies have shown that the NBD protein inhibits osteoclastogenesis. Mimicking infection with a lipopolysaccharide injection in mice resulted in activated osteoclasts and reduced bone mineral density. These responses are inhibited with the NBD peptide. In a mouse model of rheumatoid arthritis, collagen-induced arthritis, treatment with the NBD protein delayed the onset, lowered the incidence and decreased the severity of the arthritis. NF-kappaB is a target in the inflammation associated with bone destruction. A key issue is whether or not this important transcription factor can be inhibited without causing excessive adverse effects and/or toxicity.