Área de lenguas extranjeras : inglés. Propuesta B.

Se analiza el método comunicativo como método de enseñanza más eficaz en el aprendizaje de la lengua inglesa. Seguidamente, se analiza el papel del profesor y del alumno en este proceso de enseñanza y se presenta una programación de aula y su temporalización como orientación al profesor. La programación está basada en 14 unidades didácticas específicas para primero de ESO, 5 unidades didácticas comunes para primero y segundo de ESO y 14 unidades didácticas específicas para segundo de ESO. Estas unidades didácticas presentan sus objetivos y contenidos, los recursos y las actividades a realizar. Actividades que pretenden estimular la comprensión y la expresión oral y escrita. Se desarrollan las unidades didácticas School y Reading como ejemplificaciones junto con textos e imágenes complementarias para el desarrollo de las actividades.

Otimização de forma aplicando B-splines sob critério integral de tensões

This work proposes a computational methodology to solve problems of optimization in structural design. The application develops, implements and integrates methods for structural analysis, geometric modeling, design sensitivity analysis and optimization. So, the optimum design problem is particularized for plane stress case, with the objective to minimize the structural mass subject to a stress criterion. Notice that, these constraints must be evaluated at a series of discrete points, whose distribution should be dense enough in order to minimize the chance of any significant constraint violation between specified points. Therefore, the local stress constraints are transformed into a global stress measure reducing the computational cost in deriving the optimal shape design. The problem is approximated by Finite Element Method using Lagrangian triangular elements with six nodes, and use a automatic mesh generation with a mesh quality criterion of geometric element. The geometric modeling, i.e., the contour is defined by parametric curves of type B-splines, these curves hold suitable characteristics to implement the Shape Optimization Method, that uses the key points like design variables to determine the solution of minimum problem. A reliable tool for design sensitivity analysis is a prerequisite for performing interactive structural design, synthesis and optimization. General expressions for design sensitivity analysis are derived with respect to key points of B-splines. The method of design sensitivity analysis used is the adjoin approach and the analytical method. The formulation of the optimization problem applies the Augmented Lagrangian Method, which convert an optimization problem constrained problem in an unconstrained. The solution of the Augmented Lagrangian function is achieved by determining the analysis of sensitivity. Therefore, the optimization problem reduces to the solution of a sequence of problems with lateral limits constraints, which is solved by the Memoryless Quasi-Newton Method It is demonstrated by several examples that this new approach of analytical design sensitivity analysis of integrated shape design optimization with a global stress criterion purpose is computationally efficient

Cytogenetic analysis of B chromosomes in one population of the fish Moenkhausia sanctaefilomenae (Steindachner, 1907) (Teleostei, Characiformes)

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

O papel das argininas alfa-92 e alfa-141 na regulação das propriedades funcionais de hemoglobinas por íons cloreto

The oxygenation of human Hb (HbA) demands a three state model: two deoxy states To and Tx, free and complexed with anions respectively, and an oxy R state. The regulation between these states is modulated by the presence of anions, such as chloride, that binds to T state. The b inding if chloride, however, remains controversial. The aim of this work is the study of arginines 92a (a1ß2 interface) and 141a (C-terminal) as chloride binding sites. To investigate that, we have studied 92 and 141 site directed mutant species: natural mutants Hb J-Cape-Town (R92Q), desArg (R141Δ), Chesapeake (R92L), and the constructed Chesapeake desArg (R92L,141Δ). We expressed Hbs in Escherichia coli and purified. Through oxygen binding curves we measured affinity and cooperativity, in function of water effect and Bohr effect in presence and absence of chloride. Structural features were obtained through 1H NMR spectroscopy Oxygen binding properties and Bohr effect measured indicated a higher affinity and lower cooperativity in absence and presence of chloride for all mutants. Structural changes represent functional aspects of mutant Hbs, such as a significant rise in affinity or a change in cooperativity. Water activity studies conducted as a function of chloride concentration showed that the only Hb desArg follows the thre state model. The other mutant Hbs do not exhibit the Tx state, a fact confirmed by the number of water molecules bound to each Hb during the deoxy-oxy transition. This behavior suggests that the Arginine 92 site could be responsible for chloride binding to Hb, since oxygenation of 92 mutant Hbs cannot be adjusted by the three state model. However, Bohr effect showed that all mutant Hbs released~1 proton in chloride presence, different from HbA that releases ~2, suggesting a role for 141 arginine in the tertiary and quaternary Bohr effect.

Estudo da estruturacromossômica de Astyanax bockmanni (Teleostei, Characiformes) em diferentes populações: enfoque em cromossomos B

Pós-graduação em Ciências Biológicas (Zoologia) - IBB

Common Descent of B Chromosomes in Two Species of the Fish Genus Prochilodus (Characiformes, Prochilodontidae)

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Intrapartum detection of Group B streptococci colonization by rapid PCR-test on labor ward

OBJECTIVE Group B streptococci (GBS) may lead to early onset neonatal sepsis with severe morbidity and mortality of newborns. Intrapartum detection of GBS is needed. The objective was to compare a PCR-based test performed in the laboratory versus labor ward. STUDY DESIGN 300 patients were included prospectively. In phase I, swabs were analyzed by selective culture and rapid PCR in the laboratory. In phase II, swabs were analyzed accordingly, but the PCR test was conducted in labor ward. Test performances were analyzed and compared. RESULTS In phase I the rapid PCR test had a sensitivity of 85.71% and a specificity of 95.9%. The GBS colonization rate was 18.67%. Overall 8.5% of the PCR results were invalid. In phase II the PCR test showed a sensitivity of 85.71% and a specificity of 95.65%. The GBS colonization rate was 23.3%. Overall 23.5% of swabs tested with PCR were invalid. Initiation of specific, short 2-hour training for operating personnel in the labor ward reduced the invalid test rate to 13.4%. CONCLUSION The rapid PCR-based test yields adequate results to identify GBS colonization when performed in labor ward. In order to reduce the number of invalid tests a short training period is needed.

Measurement of differential production cross-sections for a ℤ boson in association with b-jets in 7 TeV proton-proton collisions with the ATLAS detector

Measurements of differential production cross-sections of a Z boson in association with b-jets in pp collisions at √s = 7TeV are reported. The data analysed correspond to an integrated luminosity of 4.6 fb−1 recorded with the ATLAS detector at the Large Hadron Collider. Particle-level cross-sections are determined for events with a Z boson decaying into an electron or muon pair, and containing b-jets. For events with at least one b-jet, the cross-section is presented as a function of the Z boson transverse momentum and rapidity, together with the inclusive b-jet cross-section as a function of b-jet transverse momentum, rapidity and angular separations between the b-jet and the Z boson. For events with at least two b-jets, the cross-section is determined as a function of the invariant mass and angular separation of the two highest transverse momentum b-jets, and as a function of the Z boson transverse momentum and rapidity. Results are compared to leading-order and next-to-leading-order perturbative QCD calculations.

Na 1 Nachlass Max Horkheimer, 674 - Forschungsprojekte über Antisemitismus, Vorurteil, Autorität: Einzeluntersuchungen (p. IX 141.1-24- IX 142.1-6)

Bettelheim, Bruno; Janowitz, Morris: "A Study on Anxiety and Social Aggression Among Different Groups of War Veterans", 1945-1947; Über die Anfälligkeit der Veteranen für antisemitische Propaganda, Typoskript, englisch, 1 Blatt; "Preliminary Study on the Evaluation of Intolerance Propaganda". Typoskript, 29 Blatt; "Isolationg the Patterns of Intolerance". Typoskript, 30 Blatt; "Distribution of Ethic Intolerance". Typsokript, 18 Blatt; "The Social Characteristics of the Intolerant". Typoskript, 22 Blatt; "Addendum to Social Characteristics of the Intolerant". Typoskript, 16 Blatt; "Impact of War Experiences". Typoskript, 26 Blatt; "Pattern on Sterepotypes". Typoskript, 14 Blatt; "Appendix No. 1: Schedule of Questions Employed in Interview". Typoskript, 6 Blatt; "Appendix No. 2: The Verteran´s Comment on the Interview Situation". Typoskript, 7 Blatt; "Preliminary Report of the Evaluation of Tolerance Propaganda". Typoskript, 19 Blatt; Einleitung zur Beschreibung des Forschungsprojekts, Typoskript, englisch, 1 Blatt; "Instructions for Interviewers". Typoskript, 2 Blat; "Questionaire". Typoskrip, 10 Blatt; "Prupose of the Investigation". Typoskript, 4 Blatt; "Schedule for Interviewers". Typoskript, 6 Blatt; "Appendix: Chicago Veterans Project". Typoskript, 3 Blatt; Memodanden zu Sitzungen mit Bruno Bettelheim, Edward Shils und Theodor W. Adorno; Memorandum 03.04.1945, Typoskript, 2 Blatt; Memorandum 15.03.1945; a) Typoskript, 3 Blatt; b) Typoskript, 4 Blatt; Memorandum 07.03.1945; a) Typoskript, 5 Blatt; b) Typoskript, 6 Blatt; University of Chicago: 1 Brief an Max Horkheimer, Chicago, 29.10.1945; University of Chicago, 1 Brief an Edward Shils undBruno Bettelheim, Chicago, 05.07.1945; Fine, Benjamin: "For Education against Intolerance and Prejudice"; Sonderdruck aus: The Menorah Journal, 1944, Vol. XXXII, No. 2, S. 161-180; Drucksachen, Materialien, 10 Blatt; Ackerman, Nathan W.: zum 'Psychoanalyst Project', 1945-1946; "Towards a Dynamic definition of Anti-Semitism". Typoskript, 13 Blatt; "The Use of Psychoanalytic Case Histories for the Study of Anti-Semitism". Typoskript, 14 Blatt; "Case Material Summary", Tabelle, 5 Blatt; "From for the Collection of Clinical Data on Anti-Minority and Anti-Semitic Attitudes". Als Typoskript vervielfältigt, 5 Blatt; "Case 2". Typoskript, 5 Blatt; "Case 24". Typoskript, 8 Blatt;

Mus Hs 707 - [Quintetto pour deux clarinetti in B, deux corni in Es, fagotto]

[Carl Oestreich]

(Table 2) B/Ca, d11B, Mg/Ca and d18O record for ODP Hole 130-806B samples

We present the first continuous records from 0 to 5 Ma (in 0.333 m.y. integrated time steps) of paired boron/calcium (B/Ca) ratios and boron isotopes (d11B) in the planktonic foraminifera Globogerinoides sacculifer (without sacc) from a site in the western equatorial Pacific Ocean (Ocean Drilling Program Site 806). These measurements, the first made in conjunction with calcification temperature (magnesium/calcium ratios) and average shell mass measurements, indicate that pH is not the sole environmental variable controlling B in planktonic foraminiferal calcite. Our data are consistent with calcification temperature exerting a primary control on B concentration and isotopic composition in planktonic foraminifera. If so, calcification temperature must be taken into account if pH for past oceans and atmospheric pCO2 are to be estimated from B isotope measurements in foraminiferal calcite. Doing so will substantially increase the uncertainty of pH estimates. Although this work was designed as a temporal study, its results define new aspects of calibrating the d11B paleo-pH tracer.