Guercino (1591-1666). Capolavori da Cento e da Roma

Un dels molts actes amb què la ciutat de Roma ha celebrat els 150 anys de la unificació d"Itàlia (1861˗2011) ha estat la presentació oficial del complex i acurat procés de restauració del Palazzo Barberini (1625˗1633). Restauració de l"edifici i, alhora, reestructuració de l"espai expositiu i del discurs museogràfic de la Galleria Nazionale di Arte Antica, dirigit tot per Rossella Vodret, reconeguda historiadora de l"art i Soprintendente per il Patrimonio Storico Artistico e del Polo Museale di Roma.

Recueil de lettres et de pièces originales.

Contient : 1 Lettre du roi « HENRY » II au connétable Anne de Montmorency ; 2 Lettre du roi « HENRY » II à « monsyeur le connetable » Anne de Montmorency ; 3 Lettre du roi « HENRY [II]... à messyeurs le connetable [Anne de Montmorency] et d'Aumalle » ; 4 Lettre du roi « HENRY [II]... à messyeurs le connetable [Anne de Montmorency] et d'Aumalle » ; 5 Lettre du roi « HENRY » II au connétable Anne de Montmorency ; 6 Lettre du roi « HENRY » II au connétable Anne de Montmorency ; 7 Lettre du roi « HENRY [II]... à mes cousins les conestable [Anne de Montmorency] et duc d'Aumalle » ; 8 Lettre du roi « HENRY » II au connétable Anne de Montmorency ; 9 Lettre du roi « HENRY [II]... à messyeurs le connetable [Anne de Montmorency] et d'Aumalle » ; 10 Lettre de « CATERINE [DE MEDICIS]... à ma cousine madame la connetable » de Montmorency ; 11 Lettre d'«ANTOYNE [DE BOURBON, duc DE VENDOME]... à monseigneur... le conestable [Anne de Montmorency]... Escript à La Fere, ce XXIme jour de juillet » ; 12 Lettre d'«ANTOYNE [DE BOURBON]... à monseigneur... le conestable [Anne de Montmorency]... D'Abbeville, ce XXVIme juillet » ; 13 Lettre de « J[EAN], cardinal DU BELLAY,... De Paris, le XIe jour de janvier M.D.XXXVII » ; 14 Lettre du roi « HENRY » II au connétable de Montmorency ; 15 Rôle des « chevalliers de l'ordre du roy » ; 16 Lettres closes « de par le roy... HENRY [II]... à nostre amé et feal le prevost de Paris ou son lieutenant... Donné à Chantilly, le XVIIe jour de septembre mil V.C.XLIX » ; 17 Lettre du roi « HENRY [II]... à mon cousin le Sr de Danville, cappitaine de deux cens chevaulx legers... Escript à Paris, le XVIIIme jour de janvier 1553 » ; 18 « Estat de la gendarmerie » ; 19 Lettre de l'amiral GASPARD DE COLIGNY, Sr DE « CHASTILLON,... à monseigneur... le duc de Montmorency, per et conestable de France... De Chastillon, ce XXVIe d'aoust 1556 » ; 20 Lettre de l'amiral GASPARD DE COLIGNY, Sr DE « CHASTILLON,... à monseigneur... le duc de Montmorency, per et connestable de France... Du chasteau de Gand, ce premier jour d'apvril 1557 » ; 21 Lettre de PHILIBERT « BABOU, evesque d'Angoulesme... à monseigneur... le duc de Montmorency, pair et conestable de France... De Romme, ce XXVe fevrier » ; 22 Lettre de « monseigneur le connestable... [ANNE DE] MONTMORENCY,... à monseigneur de La Pommeraye, conseiller et maistre d'hostel ordinaire du roy... De Vateville, ce VIIe jour de aoust... M.V.C.XL » ; 23 Lettre de « l'admyral [GASPARD DE COLIGNY, Sr DE] CHASTILLON,... à monseigneur de Humyeres, gentilhomme de la chambre du roy, capitaine et gouverneur de la ville de Peronne... D'Abbeville, le XXIme jour de juing 1557 » ; 24 Lettre du connétable ANNE DE « MONTMORENCY,... à monseigneur de Boisrigault, ambassadeur pour le roy devers messrs des ligues... De Sainct Germain, le IIIIme jour de fevrier » ; 25 Lettre de FRANÇOIS DE COLIGNY, Sr D'«ANDELOT,... à monseigneur le connestable [Anne de Montmorency]... Du chasteau de Millan » ; 26 Lettre de l'amiral GASPARD DE COLIGNY, Sr DE « CHASTILLON », à « madame de La Rochepot,... De Peronne, ce XXVe d'apvril 1557 » ; 27 Lettre de « DYANNE DE POYTIERS » à « monsieur le connestable [Anne de Montmorency]... A Annet, ce jourd'huy XVIIme jour de juing 1561 » ; 28 Lettre, en langue turque, adressée par HADJI AHMED, fils d'Abd el-Hamid, etc. (probablement reis-effendi ou ministre des affaires étrangères de la Porte), à un ambassadeur chrétien, qui n'est pas nommé, pour l'informer que, par ordre du sultan, des instructions sont données à Ibrahim Pacha, grand vizir, relativement à l'affaire d'un capitaine de vaisseau, sujet de cet ambassadeur, avec un certain Tougout Bey. Vers 1600 ; 29 Lettre, en italien, de « CARLO SFORZA, priore di Lombardia... Il di XIII di ottobre 1551 » ; 30 Lettre de FRANÇOIS DE COLIGNY, Sr D'«ANDELOT,... à madame... de La Rochepot,... A Paris, ce XXVIIe de avril 1557 » ; 31 « Estat des compaignies tant de cheval que de pied dont le roy s'entend ayder du cousté de Pietmont... » ; 32 Lettre d'«H[ENRI] DE MONTMORENCY,... à madame la connestable, duchesse de Montmorency,... De Cazal, ce XXVIIe jour d'avril 1557 » ; 33 Lettre de FRANÇOIS DE COLIGNI, Sr D'« ANDELOT,... à madame... de La Rochepot,... De Onarty, se XIIIe de mars » ; 34 Lettre de « F[RANÇOIS] DE MONTMORENCY,... à monseigneur... le duc de Montmorency, pair et connestable de France... D'Odon, ce XXXe septembre 1555 » ; 35 Lettre de « F[RANÇOIS] DE MONTMORENCY,... à monseigneur... le connestable [Anne de Montmorency]... De Ferrare, ce IIIIe septembre » ; 36 Lettre du baron de « SAINCT BLANCART,... à monseigneur... le grant maistre... De gallere devant Savonne, le XIme jour de septambre » ; 37 « Le Nombre des gallaires et des cappitaines qui en ont la charge » ; 38 Lettre d'«H[ENRI] DE MONTMORENCY,... à monseigneur... le duc de Montmorency, pair et connestable de France... De Montenare, le Xe septembre 1555 » ; 39 Lettre d'«H[ENRI] DE MONTMORENCY,... à monsieur... de Thore,... cappitaine de cinquante hommes d'armes, collonnel de la cavallerye legiere en Piedmont... De Paris, ce XIII may 1568 » ; 40 Lettre d'«OUDART DU BIES,... à monseigneur... le grant maistre, maressal de France, gouverneur et lieutenant general pour le roy en Languedocq... A Boullongne, ce XVIme jour de may » ; 41 « Le Faict des vivres et municions du camp et armée estant nagueres en Bollenois... Année [M.]V.C.XLIX » ; 42 Lettre de « F[RANÇOIS] DE MONTMORENCY,... à monseigneur... le duc de Montmorency, pair et connestable de France... De Venise, ce premier avril 1556 » ; 43 Projet d'«articles... en forme de edict... concernaus la gendarmerie et... le siege de la table de marbre ». Minute ; 44 « Copia de la lettere del duca D'ALVA al cardinale Pacecco,... Di Napoli, a 25 di gennaro 1557 » ; 45 « Copia de la lettere d'el duca D'ALVA al cardinale Carafa,... Di Napoli » ; 46 Lettre d'«ANTOYNE [DE BOURBON, duc] DE VENDOSME,... à monsieur de La Rochepot,... Escript à Ys sur Tille, le XXVIIe jour de juing... 1547 » ; 47 Lettre d'«ANTOYNE [DE BOURBON]... à monseigneur... le conestable [Anne de Montmorency]... A La Fere, ce XXIIIme mars » ; 48 Lettre du Sr « LA BROSSE,... à monseigneur... le connestable [Anne de Montmorency]... Du fort de Broctay, ce XXme jour de juillet 1552 » ; 49 « Estat abregé des parties receues par le tresorier Laguette des deniers prouvenans des empruntz » ; 50 « Autres Parties d'empruntz qui sont seures et que ledict Laguette espere recouvrer avant le temps qu'il fault fournir argent à l'Empereur » ; 51 « Autres Parties desquelles n'y a grant espoir de prompt recouvrement, lesquelles estoient couchées au premier estat des emprunctz » ; 52 Déclaration de « CAFARA » et de « DOMERGUE FABRERO,... consulz de Marselle... A Masseille, le douziesme jour d'octobre, l'an mil cinq cens cinquante ung » ; 53 Lettre de « JEHAN DE BRETAYGNE [comte DE PENTHIEVRE]... à monsieur... le duc de Montmorancy, pair et connestable de France... A Paris, ce XXme jour de febvrier 1559 » ; 54 Lettre, en italien, du gouverneur de Milan. « Da Milano, a III di junio 1548 » ; 55 Lettre, en espagnol, du Sr « MACUELO,... al illustrissimo señor el condestable de Francia... De Brussellas, a ultimo de março 1558 » ; 56 « Certiffication de... LODOWICO BIRAGO,... Di Chivasso, alli VIII di maggio 1548 ». En italien ; 57 « Estat des despences ordinaires qui se paient à Parme et La Mirandola... Faict à Ferrare, le IIIe jour de decembre 1555 »

Equipos docentes y nuevas identidades acad??micas : en educaci??n superior

Resumen basado en el de la publicaci??n

Educational development - a view from outside : national trends and institutional issues at Imperial College London. 'El desarrollo Educativo, una mirada externa: rasgos nacionales y aspectos institucionales en el caso del Imperial College London'.

Resumen tomado de la publicación

Genetic variation in the oxytocin receptor (OXTR) gene is associated with Asperger Syndrome

Background Autism Spectrum Conditions (ASC) are a group of neurodevelopmental conditions characterized by impairments in communication and social interaction, alongside unusually repetitive behaviors and narrow interests. ASC are highly heritable and have complex patterns of inheritance where multiple genes are involved, alongside environmental and epigenetic factors. Asperger Syndrome (AS) is a subgroup of these conditions, where there is no history of language or cognitive delay. Animal models suggest a role for oxytocin (OXT) and oxytocin receptor (OXTR) genes in social-emotional behaviors, and several studies indicate that the oxytocin/oxytocin receptor system is altered in individuals with ASC. Previous studies have reported associations between genetic variations in the OXTR gene and ASC. Methods The present study tested for an association between nine single nucleotide polymorphisms (SNPs) in the OXTR gene and AS in 530 individuals of Caucasian origin, using SNP association test and haplotype analysis. Results There was a significant association between rs2268493 in OXTR and AS. Multiple haplotypes that include this SNP (rs2268493-rs2254298, rs2268490-rs2268493-rs2254298, rs2268493-rs2254298-rs53576, rs237885-rs2268490-rs2268493-rs2254298, rs2268490-rs2268493-rs2254298-rs53576) were also associated with AS. rs2268493 has been previously associated with ASC and putatively alters several transcription factor-binding sites and regulates chromatin states, either directly or through other variants in linkage disequilibrium (LD). Conclusions This study reports a significant association of the sequence variant rs2268493 in the OXTR gene and associated haplotypes with AS.

Genetic variant rs17225178 in the ARNT2 gene is associated with Asperger Syndrome

Background Autism Spectrum Conditions (ASC) are neurodevelopmental conditions characterized by difficulties in communication and social interaction, alongside unusually repetitive behaviours and narrow interests. Asperger Syndrome (AS) is one subgroup of ASC and differs from classic autism in that in AS there is no language or general cognitive delay. Genetic, epigenetic and environmental factors are implicated in ASC and genes involved in neural connectivity and neurodevelopment are good candidates for studying the susceptibility to ASC. The aryl-hydrocarbon receptor nuclear translocator 2 (ARNT2) gene encodes a transcription factor involved in neurodevelopmental processes, neuronal connectivity and cellular responses to hypoxia. A mutation in this gene has been identified in individuals with ASC and single nucleotide polymorphisms (SNPs) have been nominally associated with AS and autistic traits in previous studies. Methods In this study, we tested 34 SNPs in ARNT2 for association with AS in 118 cases and 412 controls of Caucasian origin. P values were adjusted for multiple comparisons, and linkage disequilibrium (LD) among the SNPs analysed was calculated in our sample. Finally, SNP annotation allowed functional and structural analyses of the genetic variants in ARNT2. We tested the replicability of our result using the genome-wide association studies (GWAS) database of the Psychiatric Genomics Consortium (PGC). Results We report statistically significant association of rs17225178 with AS. This SNP modifies transcription factor binding sites and regions that regulate the chromatin state in neural cell lines. It is also included in a LD block in our sample, alongside other genetic variants that alter chromatin regulatory regions in neural cells. Conclusions These findings demonstrate that rs17225178 in the ARNT2 gene is associated with AS and support previous studies that pointed out an involvement of this gene in the predisposition to ASC.

Data insertion in volcanic ash cloud forecasting

During the eruption of Eyjafjallajökull in April and May 2010, the London Volcanic Ash  Advisory Centre demonstrated the importance of infrared (IR) satellite imagery for monitoring volcanic ash and validating the Met Office operational model, NAME. This model is used to forecast ash dispersion and forms much of the basis of the advice given to civil aviation. NAME requires a source term describing the properties of the eruption plume at the volcanic source. Elements of the source term are often highly uncertain and significant effort has therefore been invested into the use of satellite observations of ash clouds to constrain them. This paper presents a data insertion method, where satellite observations of downwind ash clouds are used to create effective ‘virtual sources’ far from the vent. Uncertainty in the model output is known to increase over the duration of a model run, as inaccuracies in the source term, meteorological data and the parameterizations of the   modelled processes accumulate. This new technique, where the dispersion model (DM) is ‘reinitialized’ part-­way through a run, could go some way to addressing this.

Nuclear dependence of charm production

Using data taken by SELEX during the 1996-1997 fixed target run at Fermilab, we study the production of charmed hadrons on copper and carbon targets with Sigma(-), p, pi(-), and pi(+) beams. Parametrizing the dependence of the inclusive production cross section on the atomic number A as A(alpha), we determine alpha for D(+), D(0), D(s)(+), D(+)(2010), Lambda(+)(c), and their respective anti-particles, as a function of their transverse momentum p(t) and scaled longitudinal momentum x(F). Within our statistics there is no dependence of alpha on x(F) for any charm species for the interval 0.1 < x(F) < 1.0. The average value of alpha for charm production by pion beams is alpha(meson) = 0.850 +/- 0.028. This is somewhat larger than the corresponding average alpha(baryon) = 0.755 +/- 0.016 for charm production by baryon beams (Sigma(-), p).

First observation of the Cabibbo-suppressed decays Xi(+)(c)->Sigma(+)pi(-)pi(+) and Xi(+)(c)->Sigma(-)pi(+)pi(+) and measurement of their branching ratios

We report the first observation of two Cabibbo-suppressed ecay modes, Xi(+)(c) -> Sigma(+)pi(-)pi(+) and Xi c+ -> Sigma(-)pi(+)pi(+). We observe 59 +/- 14 over a background of 87, and 22 +/- 8 over a background of 13 events, respectively, for the signals. The data were accumulated using the SELEX spectrometer during the 1996-1997 fixed target run at Fermilab, chiefly from a 600 Gev/c Sigma(-) beam. The branching ratios of the decays relative to the Cabibbo-favored Xi c+ -> Xi(-)pi(+)pi(+) are measured to be B(Xi(+)(c) -> Sigma(+)pi(-)pi(+))/B(Xi(+)(c) -> Xi(-)pi(+)pi(+)) = 0.48 +/- 0.20, and B(Xi(+)(c) -> Sigma(-)pi(+)pi(+))/B(Xi(+)(c) -> Sigma(-)pi(+)pi(+)) = 0.18 +/- 0.09, respectively. We also report branching ratios for the same decay modes of the Delta(+)(c) relative to Delta(+)(c) -> pK(-)pi(+.) (C) 2008 Elsevier B.V. All rights reserved.

Advanced functionality for radio analysis in the Offline software framework of the Pierre Auger Observatory

The advent of the Auger Engineering Radio Array (AERA) necessitates the development of a powerful framework for the analysis of radio measurements of cosmic ray air showers. As AERA performs ""radio-hybrid"" measurements of air shower radio emission in coincidence with the surface particle detectors and fluorescence telescopes of the Pierre Auger Observatory, the radio analysis functionality had to be incorporated in the existing hybrid analysis solutions for fluorescence and surface detector data. This goal has been achieved in a natural way by extending the existing Auger Offline software framework with radio functionality. In this article, we lay out the design, highlights and features of the radio extension implemented in the Auger Offline framework. Its functionality has achieved a high degree of sophistication and offers advanced features such as vectorial reconstruction of the electric field, advanced signal processing algorithms, a transparent and efficient handling of FFTs, a very detailed simulation of detector effects, and the read-in of multiple data formats including data from various radio simulation codes. The source code of this radio functionality can be made available to interested parties on request. (C) 2011 Elsevier B.V. All rights reserved.

Trigger and aperture of the surface detector array of the Pierre Auger Observatory

The surface detector array of the Pierre Auger Observatory consists of 1600 water-Cherenkov detectors, for the study of extensive air showers (EAS) generated by ultra-high-energy cosmic rays. We describe the trigger hierarchy, from the identification of candidate showers at the level of a single detector, amongst a large background (mainly random single cosmic ray muons), up to the selection of real events and the rejection of random coincidences. Such trigger makes the surface detector array fully efficient for the detection of EAS with energy above 3 x 10(18) eV, for all zenith angles between 0 degrees and 60 degrees, independently of the position of the impact point and of the mass of the primary particle. In these range of energies and angles, the exposure of the surface array can be determined purely on the basis of the geometrical acceptance. (C) 2009 Elsevier B.V. All rights reserved.

Atmospheric effects on extensive air showers observed with the surface detector of the Pierre Auger observatory

Atmospheric parameters, Such as pressure (P), temperature (T) and density (rho proportional to P/T), affect the development of extensive air showers initiated by energetic cosmic rays. We have Studied the impact of atmospheric variations on extensive air showers by means of the surface detector of the Pierre Auger Observatory. The rate of events shows a similar to 10% seasonal modulation and similar to 2% diurnal one. We find that the observed behaviour is explained by a model including the effects associated with the variations of P and rho. The former affects the longitudinal development of air showers while the latter influences the Moliere radius and hence the lateral distribution of the shower particles. The model is validated with full simulations of extensive air showers using atmospheric profiles measured at the site of the Pierre Auger Observatory. (C) 2009 Elsevier B.V. All rights reserved.

Upper limit on the cosmic-ray photon fraction at EeV energies from the Pierre Auger Observatory

From direct observations of the longitudinal development of ultra-high energy air showers performed with the Pierre Auger Observatory, upper limits of 3.8%, 2.4%, 3.5% and 11.7% (at 95% c.l.) are obtained on the fraction of cosmic-ray photons above 2, 3, 5 and 10 EeV (1 EeV equivalent to 10(18) eV), respectively. These are the first experimental limits on ultra-high energy photons at energies below 10 EeV. The results complement previous constraints on top-down models from array data and they reduce systematic uncertainties in the interpretation of shower data in terms of primary flux, nuclear composition and proton-air cross-section. (C) 2009 Elsevier B.V. All rights reserved.

Anisotropy and chemical composition of ultra-high energy cosmic rays using arrival directions measured by the Pierre Auger Observatory

The Pierre Auger Collaboration has reported. evidence for anisotropy in the distribution of arrival directions of the cosmic rays with energies E > E(th) = 5.5 x 10(19) eV. These show a correlation with the distribution of nearby extragalactic objects, including an apparent excess around the direction of Centaurus A. If the particles responsible for these excesses at E > E(th) are heavy nuclei with charge Z, the proton component of the sources should lead to excesses in the same regions at energies E/Z. We here report the lack of anisotropies in these directions at energies above E(th)/Z (for illustrative values of Z = 6, 13, 26). If the anisotropies above E(th) are due to nuclei with charge Z, and under reasonable assumptions about the acceleration process, these observations imply stringent constraints on the allowed proton fraction at the lower energies.