A web-based system for visualizing upper limb motor performance of Parkinson’s disease patients

Objective To design, develop and set up a web-based system for enabling graphical visualization of upper limb motor performance (ULMP) of Parkinson’s disease (PD) patients to clinicians. Background Sixty-five patients diagnosed with advanced PD have used a test battery, implemented in a touch-screen handheld computer, in their home environment settings over the course of a 3-year clinical study. The test items consisted of objective measures of ULMP through a set of upper limb motor tests (finger to tapping and spiral drawings). For the tapping tests, patients were asked to perform alternate tapping of two buttons as fast and accurate as possible, first using the right hand and then the left hand. The test duration was 20 seconds. For the spiral drawing test, patients traced a pre-drawn Archimedes spiral using the dominant hand, and the test was repeated 3 times per test occasion. In total, the study database consisted of symptom assessments during 10079 test occasions. Methods Visualization of ULMP The web-based system is used by two neurologists for assessing the performance of PD patients during motor tests collected over the course of the said study. The system employs animations, scatter plots and time series graphs to visualize the ULMP of patients to the neurologists. The performance during spiral tests is depicted by animating the three spiral drawings, allowing the neurologists to observe real-time accelerations or hesitations and sharp changes during the actual drawing process. The tapping performance is visualized by displaying different types of graphs. Information presented included distribution of taps over the two buttons, horizontal tap distance vs. time, vertical tap distance vs. time, and tapping reaction time over the test length. Assessments Different scales are utilized by the neurologists to assess the observed impairments. For the spiral drawing performance, the neurologists rated firstly the ‘impairment’ using a 0 (no impairment) – 10 (extremely severe) scale, secondly three kinematic properties: ‘drawing speed’, ‘irregularity’ and ‘hesitation’ using a 0 (normal) – 4 (extremely severe) scale, and thirdly the probable ‘cause’ for the said impairment using 3 choices including Tremor, Bradykinesia/Rigidity and Dyskinesia. For the tapping performance, a 0 (normal) – 4 (extremely severe) scale is used for first rating four tapping properties: ‘tapping speed’, ‘accuracy’, ‘fatigue’, ‘arrhythmia’, and then the ‘global tapping severity’ (GTS). To achieve a common basis for assessment, initially one neurologist (DN) performed preliminary ratings by browsing through the database to collect and rate at least 20 samples of each GTS level and at least 33 samples of each ‘cause’ category. These preliminary ratings were then observed by the two neurologists (DN and PG) to be used as templates for rating of tests afterwards. In another track, the system randomly selected one test occasion per patient and visualized its items, that is tapping and spiral drawings, to the two neurologists. Statistical methods Inter-rater agreements were assessed using weighted Kappa coefficient. The internal consistency of properties of tapping and spiral drawing tests were assessed using Cronbach’s α test. One-way ANOVA test followed by Tukey multiple comparisons test was used to test if mean scores of properties of tapping and spiral drawing tests were different among GTS and ‘cause’ categories, respectively. Results When rating tapping graphs, inter-rater agreements (Kappa) were as follows: GTS (0.61), ‘tapping speed’ (0.89), ‘accuracy’ (0.66), ‘fatigue’ (0.57) and ‘arrhythmia’ (0.33). The poor inter-rater agreement when assessing “arrhythmia” may be as a result of observation of different things in the graphs, among the two raters. When rating animated spirals, both raters had very good agreement when assessing severity of spiral drawings, that is, ‘impairment’ (0.85) and irregularity (0.72). However, there were poor agreements between the two raters when assessing ‘cause’ (0.38) and time-information properties like ‘drawing speed’ (0.25) and ‘hesitation’ (0.21). Tapping properties, that is ‘tapping speed’, ‘accuracy’, ‘fatigue’ and ‘arrhythmia’ had satisfactory internal consistency with a Cronbach’s α coefficient of 0.77. In general, the trends of mean scores of tapping properties worsened with increasing levels of GTS. The mean scores of the four properties were significantly different to each other, only at different levels. In contrast from tapping properties, kinematic properties of spirals, that is ‘drawing speed’, ‘irregularity’ and ‘hesitation’ had a questionable consistency among them with a coefficient of 0.66. Bradykinetic spirals were associated with more impaired speed (mean = 83.7 % worse, P < 0.001) and hesitation (mean = 77.8% worse, P < 0.001), compared to dyskinetic spirals. Both these ‘cause’ categories had similar mean scores of ‘impairment’ and ‘irregularity’. Conclusions In contrast from current approaches used in clinical setting for the assessment of PD symptoms, this system enables clinicians to animate easily and realistically the ULMP of patients who at the same time are at their homes. Dynamic access of visualized motor tests may also be useful when observing and evaluating therapy-related complications such as under- and over-medications. In future, we foresee to utilize these manual ratings for developing and validating computer methods for automating the process of assessing ULMP of PD patients.

Extended local labor markets due to high speed trains : Visualization of estimations in the Swedish national travel demand forecasting tool, SAMPERS

Wider economic benefits resulting from extended geographical mobility is one argument for investments in high-speed rail. More specifically, the argument for high-speed trains in Sweden has been that they can help to further spatially extend labor market regions which in turn has a positive effect on growth and development. In this paper the aim is to cartographically visualize the potential size of the labor markets in areas that could be affected by possible future high-speed trains. The visualization is based on the forecasts of labor mobility with public transport made by the Swedish national mobility transport forecasting tool, SAMPERS, for two alternative high-speed rail scenarios. The analysis, not surprisingly, suggests that the largest impact of high-speed trains results in the area where the future high speed rail tracks are planned to be built. This expected effect on local labor market regions of high-speed trains could mean that possible regional economic development effects also are to be expected in this area. However, the results, in general, from the SAMPERS forecasts indicaterelatively small increases in local labor market potentials.

Triggering Solar-Powered Vehicle Activated Signs using Self Organising Maps with K-means

Solar-powered vehicle activated signs (VAS) are speed warning signs powered by batteries that are recharged by solar panels. These signs are more desirable than other active warning signs due to the low cost of installation and the minimal maintenance requirements. However, one problem that can affect a solar-powered VAS is the limited power capacity available to keep the sign operational. In order to be able to operate the sign more efficiently, it is proposed that the sign be appropriately triggered by taking into account the prevalent conditions. Triggering the sign depends on many factors such as the prevailing speed limit, road geometry, traffic behaviour, the weather and the number of hours of daylight. The main goal of this paper is therefore to develop an intelligent algorithm that would help optimize the trigger point to achieve the best compromise between speed reduction and power consumption. Data have been systematically collected whereby vehicle speed data were gathered whilst varying the value of the trigger speed threshold. A two stage algorithm is then utilized to extract the trigger speed value. Initially the algorithm employs a Self-Organising Map (SOM), to effectively visualize and explore the properties of the data that is then clustered in the second stage using K-means clustering method. Preliminary results achieved in the study indicate that using a SOM in conjunction with K-means method is found to perform well as opposed to direct clustering of the data by K-means alone. Using a SOM in the current case helped the algorithm determine the number of clusters in the data set, which is a frequent problem in data clustering.

Library Permanently Closed: See Google

magine if you will the near perfect statefunded program. Yes, I know, such words sound like an oxymoron, given the track record of both state and federally-funded programs, past, present and undoubtedly in the future. Indeed, such words sound almost mythological in light of recent attempts by the federal government to spend us out of the current recession with still doubtful results (so far, a record deficit). Yet, you’re an imaginative individual and can put aside petty political persiflage and visualize such a program. Not only does this program do precisely what it said it would do, it does it so surprisingly well that, as a taxpayer, you’re completely astonished and whole-heartedly impressed.

A customização no atendimento como fator de fidelização do cliente às lojas de decoração de alto estilo

This study investigates how far customization in attendance act as clients faithfulness factor in top style interior design stores in Great Vitoria. After relative economic stability was reached with ¿Plano Real¿, customers could visualize better their money and consequently gave it more value. When clients acquire a product and demand high quality attendance they consider much beyond price. They want something new. Something that surprise. They are not satisfied only with what is best. They want the utmost. Do what is best is no longer a competitive advantage. It is now just a duty. Emphasizes application of custom-made attendance according to client specific needs as a competitive advantage-key to be pursued by companies. Analyses using extensive literature review including the world wide web source, the problem main theoretical fundaments. An intentional sample was used and interviews with closed questions were carried out with 230 clients and 18 store managers, to collect directly involved agents impressions. Conclusions show a mature customer, highly educated with good income and that demand exclusive treatment. In majority the study shows that customized attendance creates client faithfulness to top style interior design stores provided that price and product quality are adequate. Knowledge acquired with this study on attendance customization can give important contributions to top style interior design segment giving stores stimulus in the adoption of this distinctive competence facing growing global competitive market.

Impactos emocionais causados pela mudança de estilo de gestão em um hospital na cidade de São Luis-MA

The objective of this study is to identify how a health institution can minimize the emotional impacts caused by the change of a style of classic management for a participative administration, that the workers and controllers can see the institution as a dynamic organization, that must be faced as an alive system, mobile and adaptable, where they is beings that have the right to react and to answer to the stimulatons. For that, the institution can handle motivator¿s instruments that develop in the people the potential to react of adequate way to the changes proposals, as well as increasing the perspective of possible technological improvements and interpersonal relationship between the internal and external customers. To change the style to manage, to hear the staff of support and user, are not part of the routine of the heads that develop classic management. This decision demands adaptation and flexibility, study, update and psychological preparation, to face common feelings to the new. It fits to the new directors, to visualize these feelings and work to minimize, avoiding future upheavals and the confrontation of situations that can harm the production of the company, as well as the quality of the communication between the diverse dimensions of the organization people. In this study case, based in phenomenological methodology, was possible to verify, through half-open interviews and comments, how was faced the feelings caused at the old direction time, composed for military who withheld the power and determined the actions of the hospital in study, was replaced by health professionals, that saw in the work team the best option to solve the problems and the potential to carry through an administration based in adequate strategies the reality of the moment, with the objective of reaching the satisfaction of the customer. Through this work, is possible to prove the theory that the changes cause impacts that affect the behavior of the people involved and cause stress, as well as conclude that despite the new direction show themselves, during the change, much made use to make right and involve all the workers, didn¿t have traced strategies to minimize the emotional impacts caused by the changes, what made all face their feelings of doubts and anxiety without no special care. Many obtained, by themselves, to face and to adapt the new proposals, but some could not assimilate the new administrative methodology and had been moved away definitively from the institution.

Estado, sociedade e subsistema de saúde no Brasil

Estado e sociedade brasileiros conviveram em descompasso, nos anos 80. A conseqüência imediata desse fenômeno foi o atendimento insuficiente de necessidades básicas da sociedade, nesse período, com aumento da entropia em vários subsistemas sociais brasileiros, dentre os quais o subsistema de saúde. Nesta tese, trabalhando com dados econômicos, sociais e de saúde, e construindo algumas variáveis-indicadores, confrontou-se, naquele período, necessidades da sociedade com ações do Estado, na área da saúde. Utilizando técnicas estatísticas - análise gráfica, associação estatística dos indicadores selecionados (matriz de correlação de PEARSON), análise em componentes principais, análise de agrupamento e análise de regressão linear múltipla com variáveis logaritímizadas - foi possível visualizar causas e conseqüências dessa alta entropia, caracterizada por desperdício de recursos e várias situações propensas à geração de crises nas organizações, setores e instituições do subsistema de saúde brasileiro. Propõe-se um método de alocação de recursos federais, objetivando minimizar desigualdades entre as Unidades da Federação, a partir de seus desempenhos na área de saúde.

Public investment in basic education and economic growth

The main objective of this paper was to visualize the relation between government spending on basic education and the human capital accumulation process, observing the impacts of this spending on individual investments in higher education, and on economic growth. It is used an overlapping-generations model where the government tax the adult generation and spent it in basic education of the next generations. It was demonstrated that the magnitude of the marginal effect of government spending in basic education on growth crucially depends on public budget constrains. The paper explains why some countries with a lot of public investment in basic education growth at low rates. In that sense if a country has only a lot of public investment in basic education without investment in higher education it may growth at low rates because the taxation can cause distortions in the agents incentives to invest in higher education.

A formação da identidade numa perspectiva educacional

Este trabalho procura elucidar alguns conceitos teóricos de identidade, como é entendida por diferentes autores, como nós a interpretamos e como o processo educacional influencia o desenvolvimento da identidade dos adolescentes. Para isso recorremos ao fenômeno da identificação, aos conflitos intra-psíquicos, particularmente no período da adolescência, e aos vínculos de integração espacial, temporal e social. Consideramos a identidade estruturada por três níveis fundamentais: pelas estruturas mais desenvolvidas da personalidade, caracterizada pela relação interpessoal, baseada nos mecanismos de projeção e introjeção; pelos mecanismos de identificação projetiva-introjetiva e pela persistência da fusão ou estrutura sincicial primitiva que caracteriza a sociabilidade sincrética. Partimos da concepção de identificação como a forma mais primitiva de ligação afetiva. Tomamos a conquista da identidade corporal e sexual como a base das demais identidades parciais. A formação da identidade como um todo, que pressupõe uma crise na adolescência, baseia-se na problemática mais específica da formação de uma identidade sexual. Enquanto a identificação se opera através de introjeções, a identidade resulta da oposição de identificações anteriores. O processo é dialético. Somos de opinião que a identidade é formada por processos eminentemente sociais. Uma vez formada, é mantida, modificada ou mesmo remodelada pelas relações sociais. Nossa preocupação centralizou-se no processo de formação de identidade, considerado em estreita relação çom a família, a escola e a sociedade e em contínua interaçao professor-aluno, ensino-aprendizagem. Tentamos detectar as influências da educação sistematizadas no processo de formação da identidade e em especial visualizar o papel do professor no referido processo, através de pesquisa de campo. Para isso elaboramos um questionário composto de duas partes. A primeira contendo dados de identificação do aluno, da família e da escola. A segunda, composta de 40 perguntas consideradas, inferencialmente, como indicadores dos vínculos de integração espacial, temporal e social. Os sujeitos de nossa pesquisa constituiram-se de 176 alunos, na faixa etária de 14 anos, masculinos e femininos, de 5ª e 8ª series, do ensino de 1º grau das escolas da rede estadual de Divinopolis, M.G., em 1978. A análise dos dados obtidos evidenciou o desenvolvimento de nossos sujeitos em termos de identificação com os grupos primários, predominando a dependência em nível infantil.

Gestão de custos utilizando sistema de custeio por atividade-ABC: comparação entre laboratório público e privado de análises clínicas em São Luís-MA.

Neste trabalho, é abordada a importância de se utilizar novas formas (métodos) de rastreamento dos custos indiretos, em instituições pública e privada, demonstrando quanta informação uma administração responsável, na área de saúde, especificamente no setor de laboratórios de análises clínicas, pode visualizar com a utilização do Sistema de Custeio Baseado em Atividade - ABC, em substituição aos sistemas tradicionais de apuração dos custos, tipo o Absorção. Como efeito de trabalho de pesquisa buscou-se estabelecer o método de estudo de casos em duas instituições sendo uma da estrutura de saúde pública de São Luís, e outra da estrutura privada, que também presta os mesmos serviços, todos sob uma mesma remuneração – o SUS. Neste trabalho, permitem-se compará-los e verificar qual a melhor estrutura, seus problemas, limitações para a formação de seus custos. Permite também a análise comparativa entre formatos existentes, tipo o Sistema de Custeio Baseado em atividade – ABC e o sistema de custeio pro absorção. As análises obtidas permitem concluir nestes dois casos que os custos podem ser melhores determinados por uma sistemática de apuração que possibilite desenvolver diferenciais que poderão determinar a sua competitividade e a permanência dos seus serviços. Estas informações permitiriam um melhor desempenho tanto na área pública, quanto o da área privada.

O balanço social como estratégia de fortalecimento das práticas de responsabilidade socioambiental

A sociedade de hoje, não se contenta mais em cobrar das Organizações apenas o triângulo consagrado que trata especificamente da qualidade, custo e prazo. Consciente de seu papel no mundo globalizado, ela exige o envolvimento e o comprometimento dessas Organizações com as questões sociais e ambientais. Neste contexto, faz-se necessário investir na preservação da natureza, na sua relação com a sociedade e no estreito relacionamento com os envolvidos direta e indiretamente nesta difícil empreitada. Em respostas a essas demandas, a ciência contábil, frente às exigências deste mercado globalizado e em lugar do modelo gestão corporativa utilizado até recentemente, que tratava apenas dos resultados econômicos, criou o Balanço Social. Como instrumento estratégico de desenvolvimento corporativo, o Balanço Social permite que a sociedade visualize os resultados de seu comprometimento com o futuro da humanidade. Quem não procura se adaptar às novas exigências da sociedade global, tende ao fracasso. Esta pesquisa tem como agente principal apresentar se as empresas no Brasil aplicam o conceito de Responsabilidade Social em suas atividades, propondo a cidadania de forma séria e responsável. Foram observados os dados divulgados pela Petrobras, - Petróleo Brasileiro SA, Vale e Gerdau S.A,, descrevendo informações entre seus demonstrativos e relatórios com a aplicação a partir dos propostos pelo Instituto ETHOS. Foi investigado o quanto estas empresas atendem aos quesitos propostos e, com base nos resultados obtidos, indicar, o nível de seriedade que estas companhias praticam a questão. A preferência pelas empresas supracitadas como objeto de pesquisa se dá pela posição de destaque no cenário econômico nacional e mundial; por sua atuação em setores considerados de alto nível de degradação e consumo de recursos naturais; e pelo alto impacto social gerado pela organização no local onde está introduzida. Os resultados mostram que as empresas começam a visualizar as questões socioambientais, verifica-se esta informação devido aos montantes absolutos investidos, todavia esta preocupação não atingiu a idéia principal deste conceito de responsabilidade social, ao atender interesses estratégicos superficiais de promoção e auto-imagem.

Desenvolvimento do Balanced Scorecard numa indústria de alimentos

Este estudo teve por objetivo desenvolver um Balanced Scorecard para uma indústria de alimentos do Vale do Taquari. O Balanced Scorecard é um sistema de avaliação de desempenho através de indicadores, desenvolvido pelos autores Robert S. Kaplan e David P. Norton. Através da identificação de um quadro equilibrado de indicadores, o Balanced Scorecard apresenta um conjunto de medidas que fornece uma visão rápida e abrangente da empresa, buscando eliminar o excesso de informação e concentrando a atenção naquelas medidas que são fundamentais. Além das medidas financeiras, que informam sobre os resultados das ações já tomadas, apresenta também medidas operacionais de satisfação do cliente; dos processos internos e atividades de inovação e aperfeiçoamento da organização. A metodologia adotada foi de natureza qualitativa voltada ao estudo de caso. Foram realizadas entrevistas e visitas à empresa buscando os dados necessários para o desenvolvimento do trabalho e definição dos indicadores, suas metas e responsáveis, para cada uma das perspectivas. O resultado do trabalho é um Balanced Scorecard, que contempla as quatro perspectivas (financeira, cliente, processos internos e aprendizado), demonstrando a relação de causas e efeitos entre os indicadores destas perspectivas, apresentando um mapa estratégico que permite visualizar o desempenho da organização frente a sua estratégia e metas definidas.

Economic landscapes, what are they? an application to the Brazilian economy and to the sugar cane complex

In assessing the economic impact of a sector or group of sectors on a single or multiregional economy, input-output analysis has proven to be a popular method. . However, there has a problem in displaying all the information that can be obtained from this analytical approach. In this paper, we have tried to set new directions in the use of input-output analysis by presenting an improved way of looking at the economic landscapes. While this is not a new concept, a new meaning is explored in this paper; essentially, it will now be possible to visualize, in a simple picture, all the relations in the economy as well as being able to view how one sector is related to the other sectors/regions in the economy. These relations can be measured in terms of structural changes, production, value added, employment, imports, etc. While all the possibilities cannot be explored in this paper, the basic idea is given here and the smart reader can uncover all the various possibilities. To illustrate the power of analysis provided by the economic landscapes, an application is made to the sugar cane complex using an interregional inputoutput system for the Brazilian economy, constructed for 2 regions (Northeast and Rest of Brazil), for the years of 1985, 1992, and 1995.

Solid phase microextraction, mass spectrometry and metabolomic approaches for detection of potential urinary cancer biomarkers: a powerful strategy for breast cancer diagnosis

A sensitive assay to identify volatile organic metabolites (VOMs) as biomarkers that can accurately diagnose the onset of breast cancer using non-invasively collected clinical specimens is ideal for early detection. Therefore the aim of this study was to establish the urinary metabolomic profile of breast cancer patients and healthy individuals (control group) and to explore the VOMs as potential biomarkers in breast cancer diagnosis at early stage. Solid-phase microextraction (SPME) using CAR/PDMS sorbent combined with gas chromatography–mass spectrometry was applied to obtain metabolomic information patterns of 26 breast cancer patients and 21 healthy individuals (controls). A total of seventy-nine VOMs, belonging to distinct chemical classes, were detected and identified in control and breast cancer groups. Ketones and sulfur compounds were the chemical classes with highest contribution for both groups. Results showed that excretion values of 6 VOMs among the total of 79 detected were found to be statistically different (p < 0.05). A significant increase in the peak area of (−)-4-carene, 3-heptanone, 1,2,4-trimethylbenzene, 2-methoxythiophene and phenol, in VOMs of cancer patients relatively to controls was observed. Statiscally significant lower abundances of dimethyl disulfide were found in cancer patients. Bioanalytical data were submitted to multivariate statistics [principal component analysis (PCA)], in order to visualize clusters of cases and to detect the VOMs that are able to differentiate cancer patients from healthy individuals. Very good discrimination within breast cancer and control groups was achieved. Nevertheless, a deep study using a larger number of patients must be carried out to confirm the results.

Mapeamento das Instituições Federais de Ensino Superior da Região Nordeste do Brasil na Web

VANTI, Nadia. Mapeamento das Instituições Federais de Ensino Superior da Região Nordeste do Brasil na Web. Informação & informação, Londrina, v. 15, p. 55-67, 2010