Osservazioni al voto consultivo del ... avvocato Giovanni Vicini nella causa di simultanea successione di Cristiani e di Ebrei alla intestata eredità di un loro congiunto

dell' Vincenzo Berni Degli Antonj

Risposta a dell' ... Vincenzo Berni Degli antonj ... ai dubbj eccitati dal ... avvocato Francesco Gualandi sulle osservazioni al voto consultivo del ... avvocato Giovanni Vicini nella quistione di simultanae consuccessione di Cristiani e di Ebrei alle intestata eredità di un loro congiunto Cristiano

Vincenzo Berni Degli Antonj

Dubbj sulle osservazioni del signavvocato Vincenzo Berni Degli Antonj al voto consultivo del ... avvocato Giovanni Vivini nella quistione di simultanea successione di Cristiani e di Ebrei all'intestata eredità di un loro congiunto

dell' ... Francesco Gualandi

Polymorphous oligodendroglioma of Zülch revisited: a genetically heterogeneous group of anaplastic gliomas including tumors of bona fide oligodendroglial differentiation.

A polymorphous variant of oligodendroglioma was described by K.J. Zülch half a century ago, and is only very sporadically referred to in the subsequent literature. In particular, no comprehensive analysis with respect to clinical or genetic features of these tumors is available. From a current perspective, the term polymorphous oligodendroglioma (pO) may appear as contradictory in terms, as nuclear monotony is a histomorphological hallmark of oligodendrogliomas. For the purpose of this study, we defined pO as diffusely infiltrating gliomas felt to be of oligodendroglial rather than astrocytic differentiation and characterized by the presence of multinucleate tumor giant cells and/or nuclear pleomorphism. In a total of nine patients, we identified tumors consistent with this working definition. All tumors were high-grade. We characterized these with respect to clinical, histomorphological and genetic features. Despite clinical and genetic heterogeneity, we identified a subset of tumors of bona fide oligodendroglial differentiation as characterized by combined loss of heterozygosity of chromosome arms 1p and 19q (LOH 1p19q). Those tumors that lacked LOH 1p19q showed a high frequency of IDH1 mutations and loss of alpha thalassemia/mental retardation syndrome X-linked gene (ATRX) immunoreactivity, indicating a possible phenotypic convergence of true oligodendrogliomas and gliomas of the alternative lengthening of telomeres (ALT) pathway. p53 alterations were common irrespective of the 1p19q status. Histomorphologically, the tumors featured interspersed bizarre multinucleate giant tumor cells, while the background population varied from monotonous to significantly pleomorphic. Our findings indicate, that a rare polymorphous - or "giant cell" - variant of oligodendroglioma does indeed exist.

The bona fide mouse U7 snRNA gene maps to a different chromosome than two U7 pseudogenes.

The U7 snRNA, together with both common and unique snRNP proteins, forms the U7 snRNP particle. This particle is a major component of the 3' processing machinery that converts histone pre-mRNA into mature mRNA in the eukaryotic nucleus. The genes for many snRNAs are present in multiple copies and often have many pseudogenes. Southern blot experiments using U7 oligonucleotide and gene probes have identified only one strongly hybridizing band and three weakly hybridizing bands in mouse genomic DNA. Previously, two laboratories isolated genomic clones encoding one functional U7 gene and three presumed pseudogenes. Since all the genes were isolated on separate, nonoverlapping genomic fragments, the four genes are not tightly clustered in the mouse genome. In this study, we use fluorescence in situ hybridization to determine the chromosomal locations of these clones and their possible linkage to histone loci. Two of the pseudogenes map to mouse Chromosome 1, but are many megabases apart, whereas the active U7 gene maps to Chromosome 6. Possible mechanisms for this localization pattern are discussed.

Meyer Stern [Illustration] : Oberrabbiner der niederl. israel. Gemeinde in Amsterdam von 1674 bis 1699 ; Sepiazeichnung

Scan von Monochrom-Mikroform

Schrimm, Confirmation eines Ratsbeschlusses, die Juden betr. 1609

Melerowicz

Giovanni Bottesini, Brustbild

Signatur des Originals: S 36/F00185

Giovanni di Dio, Ganzfigurbildnis, mit Violoncello

Signatur des Originals: S 36/F00363

Giovanni Mario, Ganzfigurbildnis

Signatur des Originals: S 36/F01194