4-Amino-1,8-naphthalimide-based Tröger's bases as high affinity DNA targeting fluorescent supramolecular scaffolds

The synthesis and photophysical and biological investigation of fluorescent 1,8-naphthalimide conjugated Troger's bases 1-3 are described. These structures bind strongly to DNA in competitive media at pH 7.4, with concomitant modulation in their fluorescence emission. These structures also undergo rapid cellular uptake, being localized within the nucleus within a few hours, and are cytotoxic against HL60 and (chronic myeloid leukemia) K562 cell lines.

Avaliação de condicionantes ambientais a Narcissus willkommii (Samp.) A. Fernandes: bases para estratégias de conservação

Dissertação mest., Gestão e Conservação da Natureza, Universidade do Algarve, 2006

Molecular bases of classic galactosemia : searching for new therapeutic strategies

Tese de doutoramento, Farmácia (Biologia Celular e Molecular), Universidade de Lisboa, Faculdade de Farmácia, 2014

Ensino de bases de dados : testes, deteção de erros e correções

Relatório da prática de ensino supervisionada, Mestrado em Ensino de Informática, Universidade de Lisboa, 2014

Consolidação de conceitos de bases de dados com recurso à metodologia de aprendizagem baseada em projeto

Relatório da prática de ensino supervisionada, Mestrado em Ensino da Informática, Universidade de Lisboa, 2014

Estudo da sensibilidade materna em díades de risco biológico, ambiental e acumulado

Dissertação apresentada na Escola Superior de Educação de Lisboa para obtenção de grau de Mestre em Intervenção Precoce

A lei de bases da economia social portuguesa: do projeto ao texto final

ISSN 1577-4430, com fator de impacto, calculado pelo IN-RECS (http://ec3.ugr.es/in-recj/ii/Derecho_Civil-2010.htm), Bases de dados de indexação: LATINDEX, DIALNET, ISOC, COMLUDOC e AGRIS]

Information provision improvement with a geofencing event-bases system

Nowadays there is a big percentage of the population, specially young users, which are smartphone users and there is a lot of information to be provided within the applications, information provision should be done carefully and should be accurate, otherwise an overload of information will be produced, and the user will discard the app which is providing the information. Mobile devices are becoming smarter and provide many ways to filter information. However, there are alternatives to improve information provision from the side of the application. Some examples are, taking into account the local time, considering the battery level before doing an action and checking the user location to send personalized information attached to that location. SmartCampus and SmartCities are becoming a reality and they have more and more data integrated every day. With all this amount of data it is crucial to decide when and where is the user going to receive a notification with new information. Geofencing is a technique which allows applications to deliver information in a more useful way, in the right time and in the right place. It consists of geofences, physical regions delimited by boundaries, and devices that are eligible to receive the information assigned to the geofence. When devices cross one of these geofences an alert is pushed to the mobile device with the information.