A Method for Developing Ontologies from User-Generated Classication Systems

Abstract Web 2.0 applications enabled users to classify information resources using their own vocabularies. The bottom-up nature of these user-generated classification systems have turned them into interesting knowledge sources, since they provide a rich terminology generated by potentially large user communities. Previous research has shown that it is possible to elicit some emergent semantics from the aggregation of individual classifications in these systems. However the generation of ontologies from them is still an open research problem. In this thesis we address the problem of how to tap into user-generated classification systems for building domain ontologies. Our objective is to design a method to develop domain ontologies from user-generated classifications systems. To do so, we rely on ontologies in the Web of Data to formalize the semantics of the knowledge collected from the classification system. Current ontology development methodologies have recognized the importance of reusing knowledge from existing resources. Thus, our work is framed within the NeOn methodology scenario for building ontologies by reusing and reengineering non-ontological resources. The main contributions of this work are: An integrated method to develop ontologies from user-generated classification systems. With this method we extract a domain terminology from the classification system and then we formalize the semantics of this terminology by reusing ontologies in the Web of Data. Identification and adaptation of existing techniques for implementing the activities in the method so that they can fulfill the requirements of each activity. A novel study about emerging semantics in user-generated lists. Resumen La web 2.0 permitió a los usuarios clasificar recursos de información usando su propio vocabulario. Estos sistemas de clasificación generados por usuarios son recursos interesantes para la extracción de conocimiento debido principalmente a que proveen una extensa terminología generada por grandes comunidades de usuarios. Se ha demostrado en investigaciones previas que es posible obtener una semántica emergente de estos sistemas. Sin embargo la generación de ontologías a partir de ellos es todavía un problema de investigación abierto. Esta tesis trata el problema de cómo aprovechar los sistemas de clasificación generados por usuarios en la construcción de ontologías de dominio. Así el objetivo de la tesis es diseñar un método para desarrollar ontologías de dominio a partir de sistemas de clasificación generados por usuarios. El método propuesto reutiliza conceptualizaciones existentes en ontologías publicadas en la Web de Datos para formalizar la semántica del conocimiento que se extrae del sistema de clasificación. Por tanto, este trabajo está enmarcado dentro del escenario para desarrollar ontologías mediante la reutilización y reingeniería de recursos no ontológicos que se ha definido en la Metodología NeOn. Las principales contribuciones de este trabajo son: Un método integrado para desarrollar una ontología de dominio a partir de sistemas de clasificación generados por usuarios. En este método se extrae una terminología de dominio del sistema de clasificación y posteriormente se formaliza su semántica reutilizando ontologías en la Web de Datos. La identificación y adaptación de un conjunto de técnicas para implementar las actividades propuestas en el método de tal manera que puedan cumplir automáticamente los requerimientos de cada actividad. Un novedoso estudio acerca de la semántica emergente en las listas generadas por usuarios en la Web.

A MAUT approach for reusing ontologies

Knowledge resource reuse has become a popular approach within the ontology engineering field, mainly because it can speed up the ontology development process, saving time and money and promoting the application of good practices. The NeOn Methodology provides guidelines for reuse. These guidelines include the selection of the most appropriate knowledge resources for reuse in ontology development. This is a complex decision-making problem where different conflicting objectives, like the reuse cost, understandability, integration workload and reliability, have to be taken into account simultaneously. GMAA is a PC-based decision support system based on an additive multi-attribute utility model that is intended to allay the operational difficulties involved in the Decision Analysis methodology. The paper illustrates how it can be applied to select multimedia ontologies for reuse to develop a new ontology in the multimedia domain. It also demonstrates that the sensitivity analyses provided by GMAA are useful tools for making a final recommendation.

Ontology Localization

In the context of the Semantic Web, resources on the net can be enriched by well-defined, machine-understandable metadata describing their associated conceptual meaning. These metadata consisting of natural language descriptions of concepts are the focus of the activity we describe in this chapter, namely, ontology localization. In the framework of the NeOn Methodology, ontology localization is defined as the activity of adapting an ontology to a particular language and culture. This adaptation mainly involves the translation of the natural language descriptions of the ontology from a source natural language to a target natural language, with the final objective of obtaining a multilingual ontology, that is, an ontology documented in several natural languages. The purpose of this chapter is to provide detailed and prescriptive methodological guidelines to support the performance of this activity.

Introduction: Ontology Engineering in a Networked World

While ontology engineering is rapidly entering the mainstream, expert ontology engineers are a scarce resource. Hence, there is a need for practical methodologies and technologies, which can assist a variety of user types with ontology development tasks. To address this need, this book presents a scenario-based methodology, the NeOn Methodology, which provides guidance for all main activities in ontology engineering. The context in which we consider these activities is that of a networked world, where reuse of existing resources is commonplace, ontologies are developed collaboratively, and managing relationships between ontologies becomes an essential aspect of the ontological engineering process. The description of both the methodology and the ontology engineering activities is grounded in a comprehensive software environment, the NeOn Toolkit and its plugins, which provides integrated support for all the activities described in the book. Here we provide an introduction for the whole book, while the rest of the content is organized into 4 parts: (1) the NeOn Methodology Framework, (2) the set of ontology engineering activities, (3) the NeOn Toolkit and plugins, and (4) three use cases. Primary goals of this book are (a) to disseminate the results from the NeOn project in a structured and comprehensive form, (b) to make it easier for students and practitioners to adopt ontology engineering methods and tools, and (c) to provide a textbook for undergraduate and postgraduate courses on ontology engineering.

Scheduling Ontology Engineering Projects Using gOntt

In order to manage properly ontology development projects in complex settings and to apply correctly the NeOn Methodology, it is crucial to have knowledge of the entire ontology development life cycle before starting the development projects. The ontology project plan and scheduling helps the ontology development team to have this knowledge and to monitor the project execution. To facilitate the planning and scheduling of ontology development projects, the NeOn Toolkit plugin called gOntt has been developed. gOntt is a tool that supports the scheduling of ontology network development projects and helps to execute them. In addition, prescriptive methodological guidelines for scheduling ontology development projects using gOntt are provided.

Tecnología y equipos para redes ultrarrápidas

Este proyecto de fin de carrera se realiza bajo la supervisión y aprobación de la empresa BT S.A.U. Este documento pretende ser un manual básico para dar a conocer al lector los elementos, herramientas y procedimientos para llevar a cabo un proyecto de tendido de fibra óptica en España. Se compone de 5 temas cuyos contenidos paso a resumir a continuación. Tema 1. En él, se muestra una explicación a las redes de acceso y las distintas topologías FTTx necesarias para llegar al cliente, además de las tecnologías y elementos utilizados para su conexión. Tema 2. Se explicará la regulación española para el tendido de redes de acceso necesarios como son la Regulación OBA, coubicación en las centrales de Telefónica, y la Regulación MARCO, compartición de la infraestructura de Telefónica con otros operadores. Tema 3. Aquí se explica la herramienta NEON, necesaria para la “comunicación” con Telefónica para las peticiones de la compartición de su infraestructura y un apartado para la legislación municipal para el despliegue de redes de fibra. Tema 4. Expondremos el procedimiento de trabajo en campo. Hablaremos de los procedimientos del tendido de cable, las obras civiles, y finalmente las medidas para comprobar el enlace. Tema 5. Explicaremos un ejemplo de despliegue real, desde la viabilidad hasta finalmente el tendido. Tema 6. Por último, expondré mis conclusiones y trabajos futuros. Este proyecto está orientado desde un punto de vista de la infraestructura (Capa Física, Modelo OSI). ABSTRACT. This thesis project is carried out under the supervision and approval of the company BT S.A.U. This document is intended as a basic manual to expose the reader items, tools, and procedures to carry out a deployment of optical fiber project in Spain. It is composed of 5 topics whose contents I summarize below. Topic 1. In it, shows an explanation to access networks and different topologies FTTx necessary to reach the customer, as well as technologies and elements used for connection. Topic 2. In this topic will be explained the Spanish regulation for the access networks needed such as the regulation of OBA, co-location in Telefonica’s central, and the framework regulation, sharing of Telefonica infrastructure with other operators. Topic 3. Here we explain the tool NEON, necessary for the "communication" with Telefónica for requests for infrastructure sharing, and a section for municipal legislation for the deployment of fiber networks. Topic 4. We will exhibit work in field procedure. We will discuss the procedures of laying cable, civil works, and finally measures to check the link. Topic 5. We will present an example of an actual deployment, from viability until finally laying. Topic 6. Finally, I shall explain my conclusions and future work. This project is from a point of view of the infrastructure (physical layer, OSI model).

Desarrollo de ontología de títulos de grado

Dada la amplia información que rodea el dominio de programas de estudios superiores, específicamente los estudios de grado, este trabajo fin de grado propone la construcción de un modelo para representar dicha información mediante la construcción de una red de ontologías, proporcionando una definición común de conceptos importantes, y que posteriormente puede ser reutilizada para la construcción de aplicaciones que ayuden a las partes interesadas, como, estudiantes, personal académico y administrativo, a la búsqueda y acceso de información oportuna. Para la construcción de esta red de ontologías, se siguen las recomendaciones y pautas propuestas por la metodología NeOn [1a] [1b], que sigue un paradigma basado en la reutilización de recursos de conocimiento. Por otra parte, se realiza una populación de dicha red de ontologías mediante datos específicos del grado en Ingeniería Informática de la Universidad Politécnica de Madrid. La construcción de una red de ontologías siguiendo las directrices de la metodología NeOn requiere la realización de distintas actividades y tareas, como el estudio del dominio, estudio de la viabilidad, especificación de requisitos, conceptualización, formalización, implementación y mantenimiento. Se realizan también muchas otras actividades y tareas dependiendo del contexto en el que se construye la ontología. En este proyecto se hace un especial énfasis en las actividades de especificación de requisitos, conceptualización e implementación, además de la actividad de búsqueda de recursos ontológicos para su posterior reutilización. Se ha construido una red de ontologías llamada: European Bachelor Degree Ontology (EBDO) que incluye términos y conceptos importantes que se han detectado en la etapa de especificación de requisitos y que las ontologías a reutilizar no contemplan. Las decisiones de diseño para la construcción de esta nueva red de ontologías y su alineamiento con las ontologías a reutilizar se han basado en la especificación de requisitos ontológicos. Una vez definidos los conceptos relevantes de la red de ontologías, se ha implementado la red de ontologías en un lenguaje computable. Una vez que la red de ontologías se ha implementado se han realizado tareas de evaluación para corregir posible errores. Finalmente, cuando se ha obtenido una versión estable de la ontología, se ha realizado la instanciación de individuos del plan de estudios del grado en Ingeniería Informática de la Universidad Politécnica de Madrid.---ABSTRACT---Given the extensive information surrounding the domain of higher education programs, specifically bachelor degree studies, this bachelor degree project proposes the construction of a model to represent this information by building an ontology network, providing a common definition of important concepts. This network can be reused to build semantic applications that help stakeholders, such as, students, academic and organisational staff, to search and access to timely information. For the construction of this network of ontologies, guidelines and recommendations proposed by the NeOn Methodology [1a] [1b] have been followed. This methodology follows a paradigm based on the reuse of knowledge resources. Moreover, a population of this ontology network is performed with specific data of the Computer Science Degree from Universidad Politécnica de Madrid Building a network of ontologies following the guidelines of the NeOn Methodology requires the completion of various activities and tasks such as, the study of the domain, study of the feasibility, requirements specification, conceptualization, formalization, implementation and maintenance. Many other activities and tasks are also performed depending on the context in which the ontology is built. In this project a special emphasis is made on the activities of requirements specification, conceptualization and search of ontological resources for reuse and implementation. A new network of ontologies, named European Bachelor Degree Ontology (EBDO), has been built. This network includes terms and concepts that have been detected at the stage of requirements specification and that the reused ontologies have not contemplated. Design principles for the construction of this new network of ontologies and for the reused ontologies alignment have been based on the ontological specification requirements. Once the relevant concepts of the ontology network are defined, the network has been implemented in a computable ontology language. Once the network ontology is implemented, the evaluation activity has been conducted to correct the errors that the network presented. Finally, when a stable version of the ontology has been obtained, the instantiation of individuals of the study program of the Bachelor Degree in Computer Science from Universidad Politécnica de Madrid has been performed.

Modern Classics : Andy Warhol and the Renaissance Masters

"This paper explores Warhol’s final and largest series entitled the Last Supper series in which the artist appropriated the work of Leonardo da Vinci’s original fifteenth century painting, replicating the image through repetition, radical cropping, and washes of neon color. While many scholars conclude this group of works is inspired by Warhol’s religious beliefs, others interpret these paintings as typical Warhol appropriation without religious association, but consistent with the artist’s interest in the cultural commodity of famous images"

Non-Viral Gene Therapy to Cells of the bovine Intervertebral Disc

Background. Low back pain is an increasing global health problem, which is associated with intervertebral disc (IVD) damage and degeneration. Major changes occur in the nucleus pulposus (NP), with the degradation of the extracellular matrix (ECM).1 Further studies showed that growth factors from transforming growth factor β (TGFβ) and bone morphogenic proteins (BMP) family may induce chondrogenic differentiation of mesenchymal stem cells (MSC).2 Focusing on non-viral gene therapies and their possible translation into the clinics, we investigated if GDF6 (syn. BMP13 or CDMP2) can induce regeneration of degraded NP. We hypothesized that IVD transfected with plasmid over-expressing GDF6 also up-regulates other NP- and chondrogenic cell markers and enhances ECM deposition. Methods. Bovine nucleus pulposus (bNPC) and annulus fibrosus cells (bAFC) were harvested from bovine coccygeal IVD. Primary cells were then electroporized with plasmid GDF6 (Origene, vector RG211366) by optimizing parameters using the Neon Transfection system (Life Technologies, Basel). After transfection, cells were cultured in 2D monolayer or 3D alginate beads for 7, 14 or 21 days. Transfection efficiency of pGDF6 was analyzed by immunohistochemistry and fluorescent microscopy. Cell phenotype was quantified by real-time RT-PCR. To test a non-viral gene therapy applied directly to 3D whole organ culture, coccygeal bovine IVDs were harvested as previously described. Bovine IVDs were transfected by injection of plasmid GDF6 into the center. Electroporation was performed with ECM830 Square Wave Electroporation System (Harvard Apparatus, MA) using 2-needle array electrode or tweezertrodes. 72 h after tranfection discs were fixed and cryosectioned and analyzed by immunofluorescence against GDF6. Results. RT-PCR and immunohistochemistry confirmed up-regulation of GFP and GDF6 in the primary bNPC/bAFC culture. The GFP-tagged GDF6 protein, however, was not visible, possibly due to failure of dimer formation as a result of fusion structure. Organ IVD culture transfection revealed GDF6 positive staining in the center of the disc using 2-needle array electrode. Results from tweezertrodes did not show any GDF6 positive cells. Conclusion. Non-viral transfection is an appealing approach for gene therapy as it fulfills the translational safety aspects of transiency and lacks the toxic effects of viral transduction. We identified novel parameters to successfully transfect primary bovine IVD cells. For transfection of whole IVD explants electroporation parameters need to be further optimized. Acknowledgements. This project was funded by the Lindenhof Foundation (Funds “Research & Teaching”) Project no. 13-02-F. The imaging part of this study was performed with the facility of the Microscopy Imaging Center (MIC), University of Bern. References. Roughly PJ (2004): Spine (Phila), 29:2691-2699 Clarke LE, McConell JC, Sherratt MJ, Derby B, Richardson SM, Hoyland JA (2014), Arthritis Research & Therapy, 16:R67