986 resultados para Schmidt, Harry, 1886-1968.


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SALT threatened to institutionalize a bipolar world order. NWS and NNWS alike feared that the US and SU will prioritize global security principles such as systemic stability and conflict stability to Atlantic and European security. Endangered was Europe’s security and position in the future world order. Parity in strategic weapons invalidated the US nuclear umbrella. An ABM deployment and a non-transfer regime threatened Europe’s nuclear defence options. The danger of a Limited War or a denuclearization of Central Europe led to a European co-ordination on nuclear arms control to assure the preservation of the West and the future of Europe.

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Body fat distribution is a heritable trait and a well-established predictor of adverse metabolic outcomes, independent of overall adiposity. To increase our understanding of the genetic basis of body fat distribution and its molecular links to cardiometabolic traits, here we conduct genome-wide association meta-analyses of traits related to waist and hip circumferences in up to 224,459 individuals. We identify 49 loci (33 new) associated with waist-to-hip ratio adjusted for body mass index (BMI), and an additional 19 loci newly associated with related waist and hip circumference measures (P < 5 × 10(-8)). In total, 20 of the 49 waist-to-hip ratio adjusted for BMI loci show significant sexual dimorphism, 19 of which display a stronger effect in women. The identified loci were enriched for genes expressed in adipose tissue and for putative regulatory elements in adipocytes. Pathway analyses implicated adipogenesis, angiogenesis, transcriptional regulation and insulin resistance as processes affecting fat distribution, providing insight into potential pathophysiological mechanisms.

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Obesity is heritable and predisposes to many diseases. To understand the genetic basis of obesity better, here we conduct a genome-wide association study and Metabochip meta-analysis of body mass index (BMI), a measure commonly used to define obesity and assess adiposity, in up to 339,224 individuals. This analysis identifies 97 BMI-associated loci (P < 5 × 10(-8)), 56 of which are novel. Five loci demonstrate clear evidence of several independent association signals, and many loci have significant effects on other metabolic phenotypes. The 97 loci account for ∼2.7% of BMI variation, and genome-wide estimates suggest that common variation accounts for >20% of BMI variation. Pathway analyses provide strong support for a role of the central nervous system in obesity susceptibility and implicate new genes and pathways, including those related to synaptic function, glutamate signalling, insulin secretion/action, energy metabolism, lipid biology and adipogenesis.

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The goal of this thesis is to look at the critical and dissenting value of exhibitions through the examination of four cases studies, based on six exhibitions taking place between 1968 and 1998 in Latin and North America. The exhibitions belong to the history of modern and contemporary exhibitions and curating, a field of research and study that has only started to be written about in the last two decades. This investigation contributes to it, in its creation of new genealogies by connecting previously overlooked antecedents, or by proposing new relations within established lineages, at the intersection of a specific historiography; to address exhibitions, a tradition of artists acting as curators and an emerging history of curating. The examined exhibitions were put together by artists or artist collectives and were placed in a liminal position between artistic and curatorial practice. All the cases presented a distinct proposal in relation to art and social change, a fact that connects them, in their aims and modus operandi, to a Marxist and neo-Marxist critical and transformative legacy. The cases address the following connections: exhibition as political site (Tucumán Arde, 1968); exhibition as social space (The People’s Choice (Arroz con Mango), 1981); exhibition as encounter (Rooms with a view, We the People, Art/Artifact, 1987-88); and exhibition as an exchange situation (El Museo de la Calle, 1998-2001). Key to their analysis is the concept of dissensus, as put forward by Jacques Rancière. Within this theoretical framework, these exhibitions put into practice particular cases of dissensus in a given distribution of the sensible. All of them tried to deal with their thematic concerns by performing them as a praxis. They dissent with the way in which reality was formatted in their historical moment and challenge the exhibition medium itself opening new ways of doing and making in the exhibition field. Therefore, in this thesis the dissenting value of exhibitions is closely related to its main features as a medium, namely their temporality, heterogeneity and flexibility, which contribute to their potential for creative analysis and propositioning. In the case of these exhibitions, this capability is brought into play for institutional interrogation, for offering alternative cultural narratives and also for inspiring new imaginary realms.

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The paper centres on a single document, the 1968 doctoral thesis of L Bruce Archer. It traces the author’s earlier publications and the sources that informed and inspired his thinking, as a way of understanding the trajectory of his ideas and the motivations for his work at the Royal College of Art from 1962. Analysis of the thesis suggests that Archer’s ambition for a rigorous ‘science of design’ inspired by algorithmic approaches was increasingly threatened with disruption by his experience of large, complex design projects. His attempts to deal with this problem are shown to involve a particular interpretation of cybernetics. The paper ends with Archer’s own retrospective view and a brief account of his dramatically changed opinions. Archer is located as both a theorist and someone intensely interested in the commercial world of industrial design.

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Concert program for The Contemporary Group, April 21, 1968

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Dissertação apresentada à Escola Superior de Comunicação Social como parte dos requisitos para obtenção de grau de mestre em Jornalismo.

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RESUMO - Quando, finalmente, entendemos a importância dos cuidados de saúde primários, procuramos construí-los à maneira das antigas catedrais góticas dos velhos burgos medievais: desenhadas por poucos, construídas por alguns, frequentadas obrigatoriamente por todos os demais. Através de todo este esforço, aprendemos. Os cuidados de saúde primários acontecem todos os dias: quando as pessoas comuns aprendem ou fazem alguma coisa de útil à sua saúde e à dos que lhes estão próximos; sempre que comunicam com alguém habilitado a ouvi-los e apoiá-los sobre as suas dúvidas, medos, fantasias, angústias, preferências ou necessidades de saúde. Para assegurar o reforço dos cuidados de saúde primários necessitamos de conhecimentos renovados, «teorias de acção» mais elaboradas, alguma sabedoria e muita imaginação.

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Apoio financeiro da FCT e do FSE no âmbito do III Quadro Comunitário de Apoio

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Presenta las estadística de 1968 de la pesquería marítima referente a desembarques, consumo fresco de pescado, producción industrial, exportaciones y de la harina de pescado.

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Información sobre la madurez sexual de la Anchoveta peruana, que ha sido estudiado por el examen macroscópico de las gónadas durante 1961-1968, el material se recogió en Chimbote, Callao e Ilo y se comparó con datos similares de Chile. Las etapas más avanzadas de la madurez sexual fueron la base de la evaluación. El análisis pone de relieve las diferencias de tiempo de la temporada de desove entre las localidades en relación con la longitud y la edad. Los datos de Chimbote y Callao indican que la actividad sexual se extiende de agosto a marzo. Se producen dos picos de desove, uno en septiembre y otro en febrero. por otro lado, los datos de Ilo y Chile demuestran que la época de desove en la zona sur comienza en julio y termina en febrero. Estos resultados también demuestran dos puntos interesantes en relación con la longitud y la edad de anchovetas: el pico a la madurez sexual en verano es tan intenso como en el invierno, pero el predominante de pequeñas anchovetas durante el verano hace dificil de detectar la situación real y las anchovetas mayores desove durante un período más largo y con mayor intensidad que los más jóvenes. Por último, las anchovetas en la etapa más avanzada de madurez fueron más abundantes durante 1964, 1967 y que durante el resto de año cerca de Callao y Chimbote.