Multi-component quantitation of loratadine, pseudoephedrine and paracetamol in plasma and pharmaceutical formulations with liquid chromatography-tandem mass spectrometry utilizing a monolithic column

The purpose of this study was to develop a rapid, simple and sensitive quantitation method for pseudoephedrine (PSE), paracetamol (PAR) and loratadine (LOR) in plasma and pharmaceuticals using liquid chromatography-tandem mass spectrometry with a monolithic column. Separation was achieved using a gradient composition of methanol-0.1% formic acid at a flow rate of 1.0 mL min-1. Mass spectral transitions were recorded in SRM mode. System validation was evaluated for precision, specificity and linearity. Limit of detection for pseudoephedrine, paracetamol, and loratadine were determined to be 3.14, 1.86 and 1.44 ng mL-1, respectively, allowing easy determination in plasma with % recovery of 93.12 to 101.56%.

Determination of levodopa in human plasma by high performance liquid chromatography-tandem mass spectrometry (HPLC-MS/MS): application to a bioequivalence study

A sensitive, accurate and simple method using HPLC-MS/MS was developed and validated for levodopa quantitation in human plasma. Analysis was achieved on a pursuit® C18 analytical column (5 µm; 150 x 4.6 mm i.d.) using a mobile phase (methanol and water , 90:10, v/v) containing formic acid 0.5% v/v, after extracting the samples using a simple protein plasma precipitation with perchloric acid. The developed method was validated in accordance with ANVISA guidelines and was successfully applied to a bioequivalence study in 60 healthy volunteers demonstrating the feasibility and reliability of the proposed method.

Dissertatio academica, de Alandia, Maris Baltici insula, cujus partem posteriorem, consensu ampliss. facultatis philosoph. in Reg. Acad. Upsal. praeside ... mag. Petro Ekerman, ... Ad publicum examen, pro gradu, modeste defert alumnus regius, Christophorus Tärnström, Uplandus, ... In auditor. Carol. majori die XXVII. Nov. MDCCXLV. Horis ante meridiem solitis

Dedicated to: Jacobus Benzelius, Theodorus Ankarcrona, Matthias Grunerus, Olaus Thorin, Andreas Backman, Martinus Jonae Friberg, Carolus Gustavus Hallman, Andreas Sylvanus, Daniel P. Mansnerus, Daniel Lindqvist.

Försök, til en oeconomisk beskrifning, öfwer Satacunda häraders norra del : som innehåller anmärckningar i geographie, antiquiteter, physique, historia naturali, och oeconomie &c. Jemte nödige figurer. : Framgifwit af Pehr Adrian Gadd. Phil. mag.

Dedicated to: Konglige swenska wetenskaps academien.

Prostens och kyrko-herdens i Tornå mag. Johannis J. Tornæi Beskrifning, öfwer Tornå och Kemi lappmarker. Författad. År 1672

Foreword by Sam. S. Loenbom.

Afhandling om hushållningens upkomst och tilväxt i Österbotten : Första delen, med philosophiska facultetens bifall utgifven och försvarad af Hans Petter Winge, phil. mag. och Jacob Abraham Strömmer, Österbottningar. I Åbo Academies öfre lärosal den 22 Februarii 1797, på vanlig tid förmiddagen

Bound in: Dissertatio historica de paroecia Alandiae Lemland, eique annexa Lumparland / Daniel Ferdinandus Mallén. Aboae : typis Frenckellianis, [1792]

Specimen historicum, de Alandia, Maris Baltici insula, cujus partem priorem, consensu ampliss. facultatis philosoph. in Reg. Acad. Upsal. praeside ... mag. Elia Frondin, ... Publico examini submittit alumnus regius, Christophorus Tärnström, Uplandus, ... In auditor. Gustav. maj. ad diem I. Dec. MDCCXXXIX. Horis ante meridiem solitis

Dedicated to: Joanni Steuchio, Johanni Brauner, Stenoni Carolo Bielke, Maurits Wilhelm Nisbeth, Erico Klint, Gideoni Bille, Petro Bergdahl, Gudmundo Rothovio.

Beskrifning öfwer de til Sweriges krona lydande lapmarker, : innehollande kort underrättelse så wäl om landets belägenhet och beskaffenhet i gemen, som des inwånares tilstånd och husholdning, deras seder, maner och lefnadsart, samt laster och widskepelser, m.m. : Framgifwen af mag. Pehr Högström missionar och kyrkoherde wid Gelliware.

The date of publication is handwritten ʼ1747ʼ.

Dissertatio gradualis, stricturas quasdam criticas in historiam Alandiae, maris Baltici insulae, continens : Quam ... praeside mag. Johanne Bilmark, ... publice censurae submittit Daniel Backman, Borea-Fenno, in auditorio majori die IX Junii MDCCXCII, ...

Bound in: Dissertatio historica de paroecia Alandiae Lemland, eique annexa Lumparland / Daniel Ferdinandus Mallén. Aboae : typis Frenckellianis, [1792]

Dissertatio historica de paroecia Alandiae Lemland, eique annexa Lumparland, cujus partem priorem ... : praeside mag. Johanne Bilmark, ... Publice examinandam proponit Daniel Ferdinandus Mallén, alumnus regius, Alandus, in auditorio majori die XXV Februarii anni R. S. MDCCXCII, horis ante meridiem consuetis.

Dedicated to: Isaacus Nordberg.

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