O Brasil no global innovation index 2012: aprofundando o entendimento dos resultados

Este artigo analisa em detalhes os indicadores e resultado obtidos pelo Brasil na edição 2012 do Global Innovation Index (GII) [1], um dos mais importantes estudos sobre Competitividade de Países. Esta análise, por si só, pode ser útil para os interessados no Brasil e nos estudos sobre Competitividade, mas ele também demonstra que existem fatores de influência, ou influenciadores, que precisam ser considerados juntamente com a análise dos resultados dos países. Estes influenciadores, como as mudanças metodológicas, a latência dos dados, o intervalo de confiança e evolução da economia do país; ajudam a explicar os resultados negativos ou positivos do país, de um ano para outro, demonstrando os cuidados que precisam ser tomados na interpretação dos estudos de competividade. Neste artigo, evitamos traduzir a descrição do nome dos indicadores para facilitar o entendimento.

A joint theoretical and kinetic investigation on the fragmentation of (N-halo)-2-amino cycloalkanecarboxylates

A combined theoretical and experimental study to elucidate the molecular mechanism for the Grob fragmentation of different (N-halo)-2-amino cyclocarboxylates with the nitrogen atom in exocyclic position: (N-Cl)-2-amino cyclopropanecarboxylate (1), (N-Cl)-2-amino cyclobutanecarboxylate (2), (N-Cl)-2-amino cyclopentanecarboxylate (3) and (N-Cl)-2-amino cyclohexanecarboxylate (4), and the corresponding acyclic compounds, (N-Cl)-2-amino isobutyric acid (A), (N-Cl)-2-amino butyric acid (B), has been carried out. The kinetics of decomposition for these compounds and related bromine derivatives were experimentally determined by conventional and stopped-flow UV spectrophotometry. The reaction products have been analyzed by GC and spectrophotometry. Theoretical analysis is based in the localization of stationary points (reactants and transition structures) on the potential energy surface. Calculations were carried out at B3LYP/6-31+G* and MP2/6-31+G* computing methods in the gas phase, while solvent effects have been included by means the self-consistent reaction field theory, PCM continuum model, at MP2/6-31+G* and MP4/6-31+G*//MP2/6-31+G* calculation levels. Based on both experimental and theoretical results, the different Grob fragmentation processes show a global synchronicity index close to 0.9, corresponding to a nearly concerted process. At the TSs, the N-Cl bond breaking is more advanced than the C-C cleavage process. An antiperiplanar configuration of these bonds is reached at the TSs, and this geometrical arrangement is the key factor governing the decomposition. In the case of 1 and 2 the ring strain prevents this spatial disposition, leading to a larger value of the activation barrier. Natural population analysis shows that the polarization of the N-Cl and C-C bonds along the bond-breaking process can be considered the driving force for the decomposition and that a negative charge flows from the carboxylate group to the chlorine atom to assist the reaction pathway. A comparison of theoretical and experimental results shows the relevance of calculation level and the inclusion of solvent effects for determining accurate unimolecular rate coefficients for the decomposition process. © 2002 Published by Elsevier Science B.V.

Variabilidade dos elementos energéticos e ambientes em meio protegido com polietileno, sem e com cultura do pimentão (Capsicum annuum L.)

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Indicador multivariado policórico: proposta de indicador para o diagnóstico da aprendizagem organizacional

Pós-graduação em Engenharia Mecânica - FEG

Annual evolution of global, direct and diffuse radiation and fractions in tilted surfaces

Avaliou-se a evolução anual das componentes global, direta e difusa da radiação solar incidente em superfícies inclinadas a 12,85; 22,85 e 32,85º, com face voltada ao Norte, em Botucatu-SP. Foram obtidas frações radiométricas para cada componente da radiação nas superfícies supracitadas, através de razões com a radiação global e a do topo da atmosfera. A sazonalidade foi avaliada através das médias mensais dos valores diários. As medidas ocorreram entre 04/1998 e 07/2001, em 22,85º; 08/2001 e 02/2003, em 12,85º; e de 03/2003 a 12/2007, em 32,85º, com medidas concomitantes no plano horizontal (referência). Os níveis das radiações global e direta nos planos inclinados foram inferiores no período de verão e superiores entre os equinócios, quando comparadas ao plano horizontal. A radiação difusa nas superfícies inclinadas foi inferior na maioria dos meses, com perdas de até 65%. Ocorreu uma tendência de aumento das diferenças entre as superfícies horizontal e inclinada com o incremento do ângulo em todas as componentes e frações da radiação incidente. A evolução anual das precipitações pluviométricas e da razão de nebulosidade afetou diretamente a transmissividade atmosférica das componentes direta e difusa na região.

Estimativas das componentes da radiação solar incidente em superfícies inclinadas baseadas na radiação global horizontal

Statistics equations and validations with groups of annual and monthly data were evaluated for global, direct and diffuse solar radiation components incident on the tilted surface to 12.85, 22.85 and 32.85 degrees with the face North, in climate and geographical conditions of Botucatu, SP. It was employed the fractions of three components of extraterrestrial radiation in correlation with the coefficient clearness index horizontal plane, in a database of April/1998 to December/2007, whose measures at different periods in three inclinations, however concomitant to the horizontal plane. Increasing the angle of the surface led to increased scattering of the daily values of clearness index for inclined and horizontal surfaces. In annual groups, the lower performances were observed in the estimation of inclined daily diffuse radiation, with maximum Root Mean Square Error to 3.89 MJ m(-2) d(-1) (43.65%) and adjustments around 62%. In estimates of global and direct components of solar radiation on inclined planes, both annual and monthly equations can be applied, with performance dependents to climatic conditions.

Estimativa da radiação global incidente em superfícies inclinadas por modelos isotrópicos e índice de claridade

O objetivo deste trabalho foi avaliar o desempenho de modelos isotrópicos de estimativa do total de radiação incidente em superfícies inclinadas e propor estimativas com base nas correlações entre os índices de claridade horizontais e inclinados, em diferentes condições de cobertura de céu, em Botucatu, SP. Foram avaliadas superfícies com inclinação de 12,85º, 22,85º e 32,85º, pelos modelos isotrópicos propostos por Liu & Jordan, Revfeim, Jimenez & Castro, Koronakis, a teoria Circunsolar, e a correlação entre os índices de claridade horizontais e inclinados, para diferentes condições de cobertura de céu. O banco de dados de radiação global utilizado corresponde ao período de 1998 a 2007, com intervalos de 4/1998 a 8/2001 para a inclinação de 22,85º, de 9/2001 a 2/2003 para 12,85º e de 1/2004 a 12/2007 para 32,85º. O desempenho dos modelos foi avaliado pelos indicadores estatísticos erro absoluto médio, raiz quadrada do quadrado médio do erro e índice d de Wilmott. Os modelos de Liu & Jordan, Koronakis e de Revfeim apresentaram os melhores desempenhos em dias nublados, em todas as inclinações. As coberturas de céu parcialmente difuso e parcialmente aberto, nos maiores ângulos de inclinação, apresentaram as maiores dispersões entre valores estimados e medidos, independentemente do modelo. As equações estatísticas apresentaram bons resultados em aplicações com agrupamentos de dados mensais.

Desempenho do modelo global da ionosfera do IGS: avaliação no posicionamento por ponto na região sul do Brasil em período de alta atividade solar

One of the main drawbacks of the GPS accuracy for L1 users is the error due to ionosphere. This error depends on the total electron content presents in the ionosphere, as well as of the carrier frequency. Some models have been developed to correct GPS observables of the systematic error due to the ionosphere. The model more known and used is the Klobuchar model, which corrected 50-60% of the ionospheric error approximately. Alternatively, IGS (International GNSS Service) also has developed a model called Global Ionospheric Map (GIM). These maps, in format IONEX, are available in the site of the IGS, and one of the applications of them is to correct the GPS observables of the error due to ionosphere. This work aims at evaluating the quality of GPS point positioning using the IGS ionospheric model in the southerm region of Brazil. Tests carried out had shown an average improvement in the horizontal and vertical determination of 44% and 77%, respectively, when GIM is used in the point positioning.

Preliminary Criteria for Global Flares in Childhood-Onset Systemic Lupus Erythematosus

Objective. To develop widely acceptable preliminary criteria of global flare for childhood-onset systemic lupus erythematosus (cSLE).Methods. Pediatric rheumatologists (n = 138) rated a total of 358 unique patient profiles with information about the cSLE flare descriptors from 2 consecutive visits: patient global assessment of well-being, physician global assessment of disease activity (MD-global), health-related quality of life, anti-double-stranded DNA antibodies, disease activity index scores, protein: creatinine (P:C) ratio, complement levels, and erythrocyte sedimentation rate (ESR). Based on 2,996 rater responses about the course of cSLE (baseline versus followup), the accuracy (sensitivity, specificity, and area under the receiver operating characteristic curve) of candidate flare criteria was assessed. An international consensus conference was held to rank these candidate flare criteria as per the American College of Rheumatology recommendations for the development and validation of criteria sets.Results. The highest-ranked candidate criteria considered absolute changes (Delta) of the Systemic Lupus Erythematosus Disease Activity Index (SLEDAI) or British Isles Lupus Assessment Group (BILAG), MD-global, P:C ratio, and ESR; flare scores can be calculated (0.5 x Delta SLEDAI + 0.45 x Delta P:C ratio + 0.5 x Delta MD-global + 0.02 x Delta ESR), where values of >= 1.04 are reflective of a flare. Similarly, BILAG-based flare scores (0.4 x Delta BILAG + Delta 0.65 x Delta P:C ratio + 0.5 + Delta MD-global + 0.02 x Delta ESR) of >= 1.15 were diagnostic of a flare. Flare scores increased with flare severity.Conclusion. Consensus has been reached on preliminary criteria for global flares in cSLE. Further validation studies are needed to confirm the usefulness of the cSLE flare criteria in research and for clinical care.

Cross-cultural adaptation of the Portuguese version of the patient-generated subjective global assessment

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Estimativa da irradiação total sobre uma superfície inclinada a partir da irradiação global na horizontal

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Effects of isoflurane on Tei-index of myocardial performance in healthy dogs

Recently, the Tei-index, a noninvasive index that combines systolic and diastolic time intervals, has been proposed to assess global cardiac performance. However, the effects of isoflurane on the Tei-index have not been characterized. This study aimed at studying the effects of 1.0 minimal alveolar concentration isoflurane anesthesia on the pre-ejection period (PEP), left ventricular ejection time (LVET), PEP/LVET ratio, isovolumic relaxation time (IVRT), stroke index (SI), cardiac index (CI), heart rate (HR), and the Tei-index in healthy unpremedicated dogs. We observed significant increases in PEP, PEP/LVET ratio, IVRT, and TEI, whose maximal increases obtained throughout the study were 47%, 48%, 78%, and 56%, respectively. The LVET and HR did not change significantly, whereas the SI and CI decreased during anesthesia (29% and 26%, respectively). In conclusion, isoflurane produced direct effects on the Tei-index. The changes in systolic and diastolic parameters were supportive of this finding and were consistent with an overall impairment of left ventricular function during anesthesia.

BODE Index and GOLD Staging as Predictors of 1-Year Exacerbation Risk in Chronic Obstructive Pulmonary Disease

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

An essential need: creating opportunities for veterinary students and graduates to gain an appreciation of responsibilities and opportunities in global veterinary issues

Globalisation trends and biorterrorism issues have led to new concerns relating to public health, animal health, international trade and food security. There is an imperative to internationalise and strengthen global public health capacity by renewed emphasis on veterinary public health in veterinary education and increasing opportunities for elective experiential learning in public practice programmes for veterinary students. Recent experience with a US-Brazil Higher Education Consortia Program is used as an example of potential ways in which veterinary students can gain an appreciation for global veterinary issues.

Modeling hourly and daily fractions of UV, PAR and NIR to global solar radiation under various sky conditions at Botucatu, Brazil

In this analysis, using available hourly and daily radiometric data performed at Botucatu, Brazil, several empirical models relating ultraviolet (UV), photosynthetically active (PAR) and near infrared (NIR) solar global components with solar global radiation (G) are established. These models are developed and discussed through clearness index K(T) (ratio of the global-to-extraterrestrial solar radiation). Results obtained reveal that the proposed empirical models predict hourly and daily values accurately. Finally. the overall analysis carried Out demonstrates that the sky conditions are more important in developing correlation models between the UV component and the global solar radiation. The linear regression models derived to estimate PAR and NIR components may be obtained without sky condition considerations within a maximum variation of 8%. In the case of UV, not taking into consideration the sky condition may cause a discrepancy of up to 18% for hourly values and 15% for daily values. (C) 2008 Elsevier Ltd. All rights reserved.