Effects of isoflurane on Tei-index of myocardial performance in healthy dogs


Autoria(s): Sousa, Marlos Goncalves; Carareto, Roberta; De-Nardi, Andrigo Barboza; Brito, Fablo L. C.; Nunes, Newton; Camacho, Aparecido Antonio
Contribuinte(s)

Universidade Estadual Paulista (UNESP)

Data(s)

20/05/2014

20/05/2014

01/03/2007

Resumo

Recently, the Tei-index, a noninvasive index that combines systolic and diastolic time intervals, has been proposed to assess global cardiac performance. However, the effects of isoflurane on the Tei-index have not been characterized. This study aimed at studying the effects of 1.0 minimal alveolar concentration isoflurane anesthesia on the pre-ejection period (PEP), left ventricular ejection time (LVET), PEP/LVET ratio, isovolumic relaxation time (IVRT), stroke index (SI), cardiac index (CI), heart rate (HR), and the Tei-index in healthy unpremedicated dogs. We observed significant increases in PEP, PEP/LVET ratio, IVRT, and TEI, whose maximal increases obtained throughout the study were 47%, 48%, 78%, and 56%, respectively. The LVET and HR did not change significantly, whereas the SI and CI decreased during anesthesia (29% and 26%, respectively). In conclusion, isoflurane produced direct effects on the Tei-index. The changes in systolic and diastolic parameters were supportive of this finding and were consistent with an overall impairment of left ventricular function during anesthesia.

Formato

277-282

Identificador

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1800963/

Canadian Veterinary Journal-revue Veterinaire Canadienne. Ottawa: Canadian Vet Med Assoc, v. 48, n. 3, p. 277-282, 2007.

0008-5286

http://hdl.handle.net/11449/35292

WOS:000245226100010

Idioma(s)

eng

Publicador

Canadian Vet Med Assoc

Relação

Canadian Veterinary Journal-revue Veterinaire Canadienne

Direitos

openAccess

Tipo

info:eu-repo/semantics/article