116 resultados para Depressão maior


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Com o aumento da população idosa, aumentou-se também a curiosidade dos pesquisadores em investigar sobre questões relacionadas ao envelhecimento. Este é um processo que acarreta alterações motoras, funcionais e/ou cognitivas nos idosos e se associadas a uma baixa escolaridade podem levar a uma dependência funcional dos mesmos e com isso evoluindo para uma possível institucionalização se combinada com outros fatores como por exemplo, disponibilidade dos familiares. Essa mudança de ambiente em que o idoso é submetido pode lhe trazer alguns danos como depressão, perda cognitva, diminuição dos níveis de atividade física além de uma perda ainda maior da funcionalidade. Diante disso a pesquisa teve como objetivo analisar possíveis relações da escolaridade, com funcionalidade, nível de atividade física, sintomas depressivos e cognição em idosos institucionalizados e não institucionalizados fisicamente ativos, bem como comparar tais variaveis entre os grupos. Participaram deste estudo dois grupos: um grupo de 53 idosos institucionalizados de Rio Claro-SP, distribuidos em oito instituições de longa permanência, representando 20% da referida população. O outro grupo possui 53 idosos ativos da comunidade, participantes de um programa de atividade física para a terceira idade (PROFIT) da Unesp de Rio Claro-SP. Foi utilizada uma ampla bateria de testes e questionários para avaliar funcionalidade, nível de atividade física, sintomas depressivos e cognição (estado cognitivo geral, funções executivas, memória, atenção). Os dados foram analisados estatisticamente com base na estatística descritiva (médias, os desvios-padrão, valores mínimos e máximos, as medianas e os quartis superior e inferior) visando uma descrição geral do estado de ambas as populações. Para a análise entre os grupos foram utilizados os testes t de Student e U de Mann-Whitney e para... (Resumo completo, clicar acesso eletrônico abaixo)

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This study was performed as a requirement of the final course in Nursing. The study is cross-cutting, in order to identify associations between socioeconomic factors, education, child hospitalization in the ICU or not, degree of depression and level of social support (material, affective, emotional, informational and positive social interaction) and how to identify subgroups of mother - child vulnerable. Constitute themselves as subjects, mothers of children 0 to 17 years, 11 months and 29 days in hospital after the second day of hospitalization in the pediatric unit of a State Hospital Interior Paulista. Data collection was initiated after obtaining the assent of the Research Ethics Committee, as well as signing the consent form. We used the following instruments to collect data: the data form for socioeconomic and hospitalization; Beck Depression Inventory and Medical Outcomes Study (MOS). We obtained the result that there is a strong association between availability and social support and income per capita and the degree of depression, but did not find an association between time and hospital stay and whether the child was admitted to the ICU or not. We conclude that it is necessary to establish treatment services from the patient’s family, plus an appropriate social service support to meet this big demand for mothers who need support

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As unidades de paisagens naturais se diferenciam pelo relevo, clima, cobertura vegetal, solos ou até mesmo pelo arranjo estrutural e do tipo de litologia. A caracterização pedológica e o entendimento das relações entre pedologia, geologia e geomorfologia são importantes para a compreensão da distribuição dos solos numa paisagem. Considerando esta como sendo uma combinação dinâmica e instável de elementos físicos, biológicos e antrópicos, e estando em constante evolução, realizou-se o estudo das características químicas, físicas, mineralógicas e morfológicas das coberturas superficiais de uma mesma Unidade Fisiográfica na região do Planalto Ocidental e da Depressão Periférica Paulista nas proximidades de Rio Claro – SP, para a compreensão de suas relações genéticas e cronológicas na evolução das paisagens da área. Para isso foram comparados os solos de dois transectos dentro dos compartimentos, levantando e analisando as características citadas para que se possa obter informações que permitiram o diagnóstico da evolução da área, visando contribuir para o avanço das coberturas superficiais e sua relação com a evolução da paisagem. Foi possível compreender determinados processos e produtos que deram origem às coberturas superficiais e consequentemente a algumas paisagens representativas da Quadrícula de São Carlos a partir dos métodos empregados. O estudo das coberturas de alteração intempérica da região centro-oeste paulista, e seu reconhecimento, são fundamentais para o ordenamento territorial e seu planejamento regional

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Since the beginning of life in society, the human being has sought sources of energy that can be used continuously, or stored to be consumed in times of need. The various energy generation processes has enabled the human race for the implementation of many activities ranging from food preparation, handling of large industries and even the possibility of total annihilation by the availability of powerful nuclear weapons. In Brazil, whereupon the various deleterious aspects and especially the finite resources used on a large scale for the energy conservation, there is a huge devotion of society referred to the prospects for alternatives to the use of energy in local, regional and global, but overall, as it wouldn’t be different, the main factors in this scenario are economic. The fact that the unused potential of a region in the use of alternative sources of energy leads to a larger socio-environmental prejudice generalized to all. The purpose of this project is targeted for a comprehensive, systemic and integrated discussion about some of the main alternative energy sources, associated with technical procedures related to them, to contribute to a better and effective use of natural resources available in each region of the country, in order to minimize the impacts on the environment in which they are inserted.

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Aortic regurgitation (AR) leads to a left ventricle dilation and hypertrophy in response to a chronic volume overload. It is still very frequent in developing countries, for instance Brazil, and often as secondary to rheumatic fever. Usually, chronic AR is generally well tolerated for many years, when with the heart dilated the patient searches for treatment. Bidirectional association with depression and cardiovascular disease has been described. Selective serotonin reuptake inhibitors (SSRI) are widely prescribed to treat several affective disorders, especially for cardiovascular patients since they decrease arrhythmia probability. These SSRI improves cardiac function in rats submitted to stress protocols. Preliminary study from our laboratory showed that following 4 weeks of treatment with one SSRI (paroxetine) in subchronic AR rats there was a decreased in daily sodium intake and an improvement in systolic function. An increase in the central oxytocinergic transmission may be involved in this peripheral improvement to the heart. The investigations about the mechanisms underlying this improvement are necessary. Therefore the aims of this project is investigate the effects of 4 weeks of treatment of paroxetine, a SSRI, in rats with a subchronic AR over the central central gene expression of oxytocin and vasopressin using a reverse transcription polymerase chain reaction (RT-PCR)

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Os distúrbios do sistema nervoso central mais comuns relatados no mundo são a ansiedade e a depressão, com grande incidência de casos nos quais aparecem juntos. Os tratamentos utilizados na clínica além de não serem efetivos na totalidade dos casos podem, por vezes, apresentar diversos efeitos não desejados. Assim, na busca novas drogas mais efetivas e com menor incidência de efeitos adversos, a Cananga odorata (Lam.) Hook. f. & Thomson aparece como uma alternativa. Esta espécie vegetal é utilizada na aromaterapia como na prevenção do estresse, ansiedade e depressão (BIRD, 2003). A busca de novas ferramentas terapêuticas depende do uso de animais de experimentação, e com as discussões na sociedade científica sobre o uso de animais, há uma maior preocupação em se desenvolver novas técnicas experimentais onde se possa aplicar os conceitos dos 3Rs objetivando a redução (Replacement) do número de animais, sua substituição (Reduction) e o refinamento (Refinement) das técnicas experimentais. Neste trabalho avaliou-se a atividade ansiolítica e antidepressiva do óleo essencial (OE) de Cananga odorata, em animais que foram sucessivamente submetidos a testes para avaliar a atividade motora, ansiolítica e antidepressiva. Camundongos machos foram tratados por via oral com OE nas doses de 0,1; 1, 10 e 100 mg/kg, e após 30 minutos foram submetidos ao teste do Campo Aberto, da Caixa Claro-Escuro e Suspensão pela Cauda, nesta ordem, com um intervalo de 30 minutos entre eles. Os resultados indicaram que a seqüência de testes é adequada para a avaliação destas atividades com economia de tempo, animais e drogas

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The current paper presents itself as a pioneer and innovative initiative of thinking communication applying it to a very specific target audience: the homosexual segment. In the course of this study, peculiar characteristics concerning the needs and aspirations of this group have been analyzed. Data confirm this segment has one of the most meaningful market potential nowadays. In view of this, it has been carried out a detailed analysis about a Brazilian company entrepreneurship which proposed itself to enter into connection with this target. Finally it is made available to the reader a guide containing the guidelines and all the appropriate practices by the time a company decides to encompass the gay segment

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This paper aims to use the theoretical framework developed by Hyman P. Minsky for understanding the concept of financial fragility observed in the capitalist system. It is intended to clarify the concept of intrinsic instability to which capitalism is subject, which is responsible for generating more economic cycles - periods of prosperity and crashes that affect global economies - particularly the one initiated in the United States in 2008. Thus, we made theoretical analysis of the theory of economic cycles and financial instability beyond historical reviews on the biggest financial crisis since the Great Depression

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Introduction: Aortic insufficiency (AoI), a volume overload, is characterized by the diastolic reflux of blood from the regurgitating aorta to the left ventricle. This effect results from malfunctioning aortic cusps. The main cause of AoI in developing countries is rheumatic fever, including Brazil, and valvar degeneration in developed countries. There is a strong association between cardiovascular diseases and depression. Selective serotonin reuptake inhibitors (SSRI) are one of the most prescribed antidepressants in the world. Previous studies of our laboratory showed that the utilization of a SSRI, paroxetine, improved cardiac function in rats with sub-chronic AoI and reduced the daily ingestion of hypertonic sodium (NaCl 0,3M). Cardiovascular diseases can determine behavior changes like increase of anxiety, and it is yet unknown if AoI would determine anxiety or anhedonia, incapacity of obtaining pleasure through physical or sensorial experiences. A possible target for SSRI action could be a change in the expression of enzyme isoforms that collaborate in the contractile function of the heart muscle, like the heavy chains of myosine, the sarcoplasmatic reticulum Ca2+/ATPase (SERCA) and its regulator protein, phospholamban (PLB). Objectives: Evaluation of behavior parameters for anxiety and anhedonia state and genic expression of a-myosine, b-myosine, SERCA2a and PLB in the heart tissue of rats with subchronic AoI that received treatment with an SSRI (paroxetine) for 4 weeks. Methods: Surgery to induce AoI was performed on male Wistar rats, anxiety was evaluated by the elevated plus-maze (EPM) and state of anhedonia was tested by ingestion of 2% sucrose solution. After euthanasia the heart tissue was collected and total RNA was extracted to be analyzed by the RT-qPCR method. Results: Heart fractional shortening was preserved in rats with AoI that were treated compared to rats with AoI that were not treated. There was no statistically ...

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Resenha do livro A tristeza perdida de Allan V. Horwitz e Jerome C. Wakefield - Summus Editorial 2010

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Pós-graduação em Fisiopatologia em Clínica Médica - FMB

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Pós-graduação em Medicina Veterinária - FCAV

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This article is based on the author's clinical practice in the area of public health, and discusses depression as it is known today. Essentially, the author questions the practice of labeling depression as a psychopathological condition. The author also questions today’s trend of seeing a subject’s suffering as a "malaise," or a “disorder.” The possibility is brought up of understanding it as a "demand for analysis." Finally, the article is meant as a contribution to the ethics of psychoanalysis focused on the subject and the possibilities of psychoanalysis in subjectivating this "malaise."

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The goal of this paper was to determine the effects of seven diets with differents fatty acids sources in hematology of Nile tilapia before and after cold stimulus. Seven diets, with 3% of fatty acid source, were formulated: soybean oil (OS); fish oil (OP); beef tallow (SB) and mixtures of OS+OP; OS+SB; OP+SB e OS+OP+SB. Fish (112 male of Nile tilapia of 30,0 +/- 2,65g) were totally randomly distributed, with four replicates, into 28 plastic aquaria (40 L; 4 fish per aquarium). Fish were fed four times per day for 35 days. At 35th day and also after seven days cold stimulus blood was collected and the profile hematological was evaluated. Leucocytes numbers were reduced in fish fed a SB and fish oil combination diet and were highest in fish fed SB diet before cold stimulus. Plasma protein was reduced in fish fed soybean oil diets and highest in fishes fed a combination of soybean oil, fish oil and SB diets. Anything fatty acids source promotes effective changes in fish health and cold tolerance promotion. Cold don't drastically reduced fish general health status.