Distribuição regional da ventilação pulmonar em indivíduos com insuficiência cardíaca crônica após serem submetidos a um programa de treinamento da musculatura inspiratória e sua correlação com dados funcionais

Introduction: Chagas Disease is a serious public health problem, with 5 million infected individuals in Brazil. Of these, approximately 30% develop chronic Chagas cardiomyopathy (CCC), where the main symptoms are fatigue and dyspnea. Objective: To correlate maximal exercise capacity with pulmonary function, inspiratory muscle strength and quality of life in patients with CCC. Methodology: Twelve individuals suffering from CCC were evaluated (7 men), with a mean age of 54.91± 8.60 years and the following inclusion criteria: functional class II and III according to the New York Heart Association (NYHA); left ventricle ejection fraction below 45%; clinical stability (> 3 months); symptom duration > 1 year, body mass index (BMI) < 35Kg/m2 and non-smokers or ex-smokers with a history of smoking <10 packs/day. All subjects were submitted to spirometry, manometer testing, maximal cardiopulmonary exercise testing (CPX) and a quality of life questionnaire (Minnesota). Results: A negative correlation was observed between VO2máx and MLHFQ scores (r=-0.626; p=0.03) and a positive association with MIP (r=0.713; p=0.009). Positive correlations were also recorded between MIP and spirometric variables [FEV1(r=0.825;p=0.001 ), FVC(r=0.66;p=0.01 and FEF25-75%(r=0.639;p=0.02)]. Conclusion: The present study demonstrated that in patients with CCC: VO2MAX is directly related to inspiratory muscle strength and quality of life, while deteriorating lung function is directly associated with respiratory muscle weakness

Condutividade térmica de rochas: uma aplicação para granitos ornamentais

This dissertation focuses on rock thermal conductivity and its correlations with petrographic, textural, and geochemical aspects, especially in granite rocks. It aims at demonstrating the relations of these variables in an attempt to enlighten the behavior of thermal effect on rocks. Results can be useful for several applications, such as understanding and conferring regional thermal flow results, predicting the behavior of thermal effect on rocks based upon macroscopic evaluation (texture and mineralogy), in the building construction field in order to provide more precise information on data refinement on thermal properties emphasizing a rocky material thermal conductivity, and especially in the dimension stone industry in order to open a discussion on the use of these variables as a new technological parameter directly related to thermal comfort. Thermal conductivity data were obtained by using Anter Corporation s QuicklineTM -30 a thermal property measuring equipment. Measurements were conducted at temperatures ranging between 25 to 38 OC in samples with 2cm in length and an area of at least 6cm of diameter. As to petrography data, results demonstrated good correlations with quartz and mafics. Linear correlation between mineralogy and thermal conductivity revealed a positive relation of a quartz percentage increase in relation to a thermal conductivity increase and its decrease with mafic minerals increase. As to feldspates (K-feldspate and plagioclase) they show dispersion. Quartz relation gets more evident when compared to sample sets with >20% and <20%. Sets with more than 20% quartz (sienogranites, monzogranites, granodiorites, etc.), exhibit to a great extent conductivity values which vary from 2,5 W/mK and the set with less than 20% (sienites, monzonites, gabbros, diorites, etc.) have an average thermal conductivity below 2,5 W/mK. As to textures it has been verified that rocks considered thick/porphyry demonstrated in general better correlations when compared to rocks considered thin/medium. In the case of quartz, thick rocks/porphyry showed greater correlation factors when compared to the thin/medium ones. As to feldspates (K-feldspate and plagioclase) again there was dispersion. As to mafics, both thick/porphyry and thin/medium showed negative correlations with correlation factor smaller than those obtained in relation to the quartz. As to rocks related to the Streckeisen s QAP diagram (1976), they tend to fall from alcali-feldspates granites to tonalites, and from sienites to gabbros, diorites, etc. Thermal conductivity data correlation with geochemistry confirmed to a great extent mineralogy results. It has been seen that correlation is linear if there is any. Such behavior could be seen especially with the SiO2. In this case similar correlation can be observed with the quartz, that is, thermal conductivity increases as SiO2 is incremented. Another aspect observed is that basic to intermediate rocks presented values always below 2,5 W/mK, a similar behavior to that observed in rocks with quartz <20%. Acid rocks presented values above 2,5 W/mK, a similar behavior to that observed in rocks with quartz >20% (granites). For all the other cases, correlation factors are always low and present opposite behavior to Fe2O3, CaO, MgO, and TiO2. As to Al2O3, K2O, and Na2O results are not conclusive and are statistically disperse. Thermal property knowledge especially thermal conductivity and its application in the building construction field appeared to be very satisfactory for it involves both technological and thermal comfort aspects, which favored in all cases fast, cheap, and precise results. The relation between thermal conductivity and linear thermal dilatation have also shown satisfactory results especially when it comes to the quartz role as a common, determining phase between the two variables. Thermal conductivity studies together with rocky material density can function as an additional tool for choosing materials when considering structural calculation aspects and thermal comfort, for in the dimension stone case there is a small density variation in relation to a thermal conductivity considerable variation

Análise de agrupamentos dos dados de DFA oriundos de perfis elétricos de indução de poços de petróleo

The main objective of this study is to apply recently developed methods of physical-statistic to time series analysis, particularly in electrical induction s profiles of oil wells data, to study the petrophysical similarity of those wells in a spatial distribution. For this, we used the DFA method in order to know if we can or not use this technique to characterize spatially the fields. After obtain the DFA values for all wells, we applied clustering analysis. To do these tests we used the non-hierarchical method called K-means. Usually based on the Euclidean distance, the K-means consists in dividing the elements of a data matrix N in k groups, so that the similarities among elements belonging to different groups are the smallest possible. In order to test if a dataset generated by the K-means method or randomly generated datasets form spatial patterns, we created the parameter Ω (index of neighborhood). High values of Ω reveals more aggregated data and low values of Ω show scattered data or data without spatial correlation. Thus we concluded that data from the DFA of 54 wells are grouped and can be used to characterize spatial fields. Applying contour level technique we confirm the results obtained by the K-means, confirming that DFA is effective to perform spatial analysis

Estudo da correlação das características dermatoglífica e somatotípica com as qualidades físicas das atletas de voleibol da Seleção Infanto-juvenil do Estado do Rio Grande do Norte

The purpose of the present study is to identify the dermatoglyphic and somatotypic characteristics and the physical qualities of athletes from the under-17 State volleyball team, in Rio Grande do Norte, Brazil. The sample was composed of athletes, n = 14, aged 15.0 ± 0.88 years, weight (Kg) 58.3 ± 5.90 and height (cm) 169.4 ± 7.97, members of the referred team. For data collection Cummins & Midlo s (1942), o dermatoglyphic method and Heath & Carter s (1967) somatotypic method were used and to evaluate physical qualities, 2400m, 50m, Shuttle Run, abdominal , Sargent test and medicine-ball toss were performed. Fingerprints show that the group presents genetic predisposition for the following physical qualities: explosive force and velocity. As to somatotype, the group was endo-ectomorphic. At physical evaluation the group presented low Vo2 max values and reasonable levels of explosive force, local muscular endurance, agility and velocity. We conclude that: according to the dermatoglyphic model observed, the group needs training strategies to improve coordination and agility; somatotype reveals the necessity for reducing fat levels and increasing muscular mass; the evaluation of physical qualities demonstrates the need for better physical preparation. This study traces the profile of the under-17 volleyball player from Rio Grande do Norte, with respect to genetic and somatotypic aspects and physical qualities, which will serve as a parameter for future state teams

Correlação entre torque, equlíbrio e função do joelho após reconstrução do LCA

Background: Several studies emphasize the importance of assessing the knee function after anterior cruciate ligament (ACL) reconstruction. The influence of several variables on the function of these patients has been analyzed, but there is no consensus in the science literature. Purpose: To evaluate the correlation between the torque and balance on the knee function after ACL reconstruction. Methods: 23 males patients with ACL reconstruction were tested. The procedures of the study included analysis of concentric peak torque at 60o/s and 180o/s of quadriceps femoris and hamstring muscle with a isokinetic dynamometer. The balance in single-limb stance was measured with stabilometry. The functional performance were performed by two hop tests. To estimate the subjective function of the patients was applied Lysholm Knee Scoring Scale and a Global Rating scale. Results: The analysis of data showed a moderate positive correlation between knee extensor torque and functional performance tests (r= 0,48; p=0,02). A moderate negative correlation was found between the two variables of the stabilometry center of pressure and average speed of centre of pressure and the Global Rating scale (r = -0.4, p = 0,04 and r = -0,49, p = 0 ,02, respectively). No correlation was found between peak torque and balance in single-limb stance. Conclusion: The results of the present study suggest that knee extensor strength and postural balance have some influence on knee function in patients after ACL reconstruction

Correlação entre os parâmetros do cortisol salivar e o fenótipo de fragilidade em idosos institucionalizados

Introduction: The Frailty Syndrome is characterized by the decrease of energy reserve and the reduced resistance to stressors. Studies indicate that the neuroendocrine markers can be related to the appearance of this syndrome. The main endocrine answer to stress is the increase of cortisol levels. Objective: To analyze the correlation between the frailty syndrome the salivary cortisol in elderly residing in nursing homes. Method: A traversal study was accomplished, in João Pessoa city, PB, with a sample composed by 69 institutionalized elderly. The collected data refer to the frailty phenotype (weight loss, exhaustion, slowness, weakness, and lower level of physical activity) and to salivary cortisol parameters (first measure - 6-7h; second measure - 11-12h; third measure - 16-17h). In the statistical analysis the Pearson s correlation test was used, Chi square Test and Anova and Simple Linear Regression analyses. Results: The sample was composed by 37.7% of men and 62.3% of women, with age average of 77.52 (±7.82). There was a percentile of 45.8% frail elderly. The frail elderly obtained higher cortisol values in the third measure (p=0.04) and the frailty load was significantly associated to the first measure (r=0.25, p=0.04). The simple linear regression analysis presented a determination rate (R2=0.05) between frailty load and first cortisol measure. Conclusion: The largest cortisol values in the morning and before sleeping among the frail elderly supply indications that can have a relationship of cortisol increase levels and the frailty presence in elderly from nursing homes.

Cisto dentígero: estudo epidemiológico, correlação clinicopatológica e caracterização de uma possível variante inflamatória

The aim of this study was to evaluate the clinical and pathological features of cases diagnosed as dentigerous cyst by the Department of Oral Pathology, School of Dentristy at the Federal University of Rio grande do Norte, attempting the possible correlation between histomorphological findings and epidemiological data contained at the files of the patients, in order to define a suggested variation of lesion named inflammatory dentigerous cyst. It was verified that dentigerous cyst are more frequently present in the earfy three decades of life, with the majority of cases occuring in the second decade (40,740/0 ), and also male (57,41%) and white patients (68,52%) were most affected. In relation to anatomic site, the dentigerous cyst was more prevalent at anterior maxila and posterior mandible, showing, usually, a slow growth pattem. The majority of lesions were asymptomatic and the radiographic observed was frequently na unilocular radiolucency. In regard to the histomorphological analysis, it was noticed that the lesions showed commonly a thin epithelium, with a capsule of fibrous connective tissue, richly vascularized and collagenized with an intense mononuclear inflammatory infiltrate. Finally, clinicopathological was performed and it was find out that cysts that showed a thick epithelium, with a high degree of vascularization and collagenization, intense inflammatory infiltrate in the cystic capsule, were located in the pre-molares region, in patients under 12 years old and the majority showing painfull sintomatology, properly, compatible with inflammatory dentigerous cyst. The findings of the present study indicate that, probably, there is a variant of the dentigerous cyst, and therefore, we suggest the denomination inflammatory follicular cyst for this entity

Carcinoma epidermóide de língua :correlação clínica, histológica e imuno-histoquímica

Oral squamous cell carcinoma is the most common malignant neoplasm in oral cavity. Several studies have been carried out to establish biologic behaviour criteria of this neoplasm. Thus, the purpose of this experiment was to performe a clinic, morphologic and immunohistochemical analysis, by the expression of cytokeratins 7, 10, 13, 14, 16 and 19 in 30 cases of tongue squamous cell carcinoma from the files of Dr. Luiz Antônio Hospital (Natal-RN). It was verifeid of the immunoexpression the correlation clinic estadiament and histologic gradation system proposed by Bryne (1998), in order to investigate the use of these intermediate filaments as an indicator of tumour progression. Data was collected from the patients file and it was observed that information regarding sex, age and race was resemble to the literature. Data obtained from disease evolution, clinic estadiament, metastasis and expression of cytokeratins 7, 10, 13, 14, 16 and 19 was submited to statistical analysis (Test K2), which showed that only the histologic gradation didn t demonstrated significant correlation to the clinic variables. The expression the cytokeratins presented variation in the analysed tumours. CK 10 expression showed significant correlation to metastasis, and the presence of CK 16 was related to disease evolution (obit/remission) and also with the T3 and T4 of TNM. These results evidenced that metastasis and TNM showed a good efficacy as a prognostic indicator. The histologic gradation proposed by Bryne (1998) didn t reflect the biologic behaviour of the studied tongue squamous cell carcinoma, and the analysis of some intermediate filaments of cytokeratins seems to reflect the biologic behaviour and agressivity of some oral squamous cell carcinoma

Sismicidade e correlação com feições geológicas: o caso do lineamento Pernambuco e seu entorno

This thesis presents and discusses the results of the various seismic areas in the State of Pernambuco, with the aim of having a vision of regional seismicity and its causes. To the papers published in journals were added two new original works submitted to international journals, dealing with seismic areas located in the counties of São Caetano, Cupira, and Agrestina. All seismic areas mentioned in this thesis are located on the Pernambuco Lineament and its surroundings (both in branches or single faults within 40 km of it). The Pernambuco Lineament is a Neoproterozoic shear zone of continental-scale that deformed the Borborema Province, and presents as branches, shear zones with NE-SW direction. The new submitted papers are from the analysis of data collected by three local networks of stations that operated in the following areas: network SO07 (seismicity in the district of Santa Luzia - São Caetano, 2007), network BM10 (data from seismic areas of Serra Verde ( Cupira) and Barra do Chata (Agrestina), in 2010), network SO10 (seismicity near the urban center of São Caetano in 2010). These data were used for determining the hypocenters and focal mechanisms in order to discuss the relationship between the seismicity and geological features of the area. The new mechanisms obtained, as well as the previously published allowed the determination of the direction of the average stress in the region. The direction of stress in the region involving the various seismic areas, now or previously studied, is quite stable and approximate EW direction (SHmax). The correlation between seismicity and geological features is observed on the lineament and north of it. In the south (Cupira and Agrestina), in seismic areas nearby shear zones NE-SW, there is no correlation and seismogenic EW normal faults are active and its motion is compatible with regional stresses. It is probable that these active faults are more recent than the Neoproterozoic, probably of the Cretaceous period, when the last great movement of the Pernambuco Lineament occurred

Análise de terrenos na porção setentrional da Província Borborema, NE do Brasil: integração de dados geológicos e gravimétricos

It is presently assumed that the Borborema Province resulted from a complex collisional process associated with the convergent movement of plates, possibly involving amalgamation and accretion of microplates. This process was consolidated at the end of the Brasiliano event. It is investigated the possible limits for the tectonostratigraphic terranes in the northern portion of the province based on an integrated study of geological and gravity data. The study area comprises the portion of the Borborema Province located north of the Patos Lineament, limited by longitudes 33º00 W and 43º29 44"W and latitudes 1º36 S and 8º00 S. A revision of the regional geology allowed to identify areas presenting contrasting geological attributes, possibly representing different terranes whose limits are always shear zones of Brasiliano-age. The Sobral-Pedro II shear zone is the only one undoubtedly presenting geological attributes of sutures zones. The other shear zones are very likely associated with a geodinymic context of accretion, involving oblique collisions (docking), transcurrent and/or transforming sutures, and deep intracrustal shear zones. The gravity data contributed as a tool to identify strong lateral contrasts of density inside the upper crust possibly associated with crustal blocks tectonically juxtaposed. The dominant long wavelength anomaly in the Bouguer anomaly map is an expressive gradient, grossly parallel to the continental margin, caused by density variation across the crust-mantle interface in the transition from the continental crust to the oceanic crust originated by the separation between South America and Africa. Medium to small wavelength anomalies are due to intracrustal heterogeneities such as different Precambrian crustal blocks, Brasiliano-age granites and Mesozoic sedimentary basins. A regional-residual separation of the Bouguer anomaly map was performed in order to enhance in the residual map the effect due to intracrustal heterogeneities. The methodology used for this separation was a robust polinomial fitting. The inversion of residual gravity field resulted in a density contrast map (Δρ), in an equivalent layer that provided more accurated anomalies contours and consolidated the model which the sources of residual anomalies are located in the upper part of the present crust. Based on the coincidence of gravity lineaments in the residual map and Brasiliano shear zones, and using additional geological information, the following shear zones are proposed as limits between terranes: Patos shear zone, Sobral-Pedro II shear zone, Picuí-João Câmara shear zone, Remígio-Pocinhos shear zone, Senador Pompeu shear zone, Tauá shear zone, and Portalegre shear zone. Based on the geological/geophysical information it is attributed a higher level of confidence to the first three proposed limits(Patos, Sobral Pedro II, and Picuí-João Câmara shear zones). From west to east, these shear zones individualize the following terranes: Northwest of Ceará terrane, Central Ceará terrane, Tauá terrane, Orós-Jaguaribe terrane, Seridó terrane, and São José de Campestre terrane. In our study, the Rio Piranhas and Patos terranes are questioned because their previously proposed limits do not present good geological and gravimetric evidences. On the other hand, the previously proposed Cearense terrane is now subdivided into Central Ceará and Tauá terranes. Two residual gravity profiles located in the Seridó belt were interpreted using 2 ½ D direct gravity modeling. The main result of the modeling process is that all anomalies, with the exception of one, can be explained by outcroppring bodies, therefore restricted to the upper part of the present crust

Estruturação do grupo Serra Grande região de Santana do Acaraú- CE e a reativação do lineamento Sobral Pedro II, integração com dados geofísicos

The study area is located in the NW portion of the Ceará state nearby the city of Santana do Acaraú. Geologically it lies along the Sobral-Pedro II lineament which limits the domains of Ceará Central and Noroeste do Ceará, both belonging to the Borborema Province.The object of study was a NE trending 30km long siliciclastic body (sandstone and conglomerate) bounded by transcurrent dextral faults. The sediments are correlated to the Ipú Formation (Serra Grande Group) from the Parnaiba basin, which age is thought to be Siluro-Devonian. Existing structural data shown that bedding has higher but variable dips (70-45) near the borders faults and much lower to subhorizontal inward the body. The brittle deformation was related to a reactivation, in lower crustal level, of the Sobral-Pedro II lineament (Destro (1987, 1999; Galvão, 2002).The study presented here was focused in applying geophysicals methods (gravimetry and seismic) to determine the geometry of the sandstone/conglomeratic body and together with the structural data, to propose a model to explain its deformation. The residual anomalies maps indicate the presence of two main graben-like structures. The sedimentary pile width was estimated from 2D gravimetric models to be about 500-600 meters. The 3D gravimetric model stressed the two maximum width regions where a good correlation is observed between the isopach geometry and the centripetal strike/dip pattern displayed by the sediments bedding. Two main directions (N-S and E-W) of block moving are interpreted from the distribution pattern of the maximum width regions of the sedimentary rock

Geoprocessamento de dados meteo-oceonográficos (cor do oceano e temperatura da superfície do mar) aplicado ao monitoramento ambiental na costa setentrional do Rio Grande do Norte

Orbital remote sensing has been used as a beneficial tool in improving the knowledge on oceanographic and hydrodynamic aspects in northern portion of the continental shelf of Rio Grande do Norte, offshore Potiguar Basin. Aspects such as geography, temporal and spatial resolution combined with a consistent methodology and provide a substantial economic advantage compared to traditional methods of in situ data collecting. Images of the Moderate Resolution Imaging Spectroradiometer (MODIS) sensor onboard NASA's AQUA satellite were obtained to support systematic data collections related to the campaign of environmental monitoring and characterization of Potiguar Basin, held in May 2004. Images of Total Suspension Matter (TSM) and values of radiance standard were generated for the calculation of concentrations of total suspension matter (TSM), chlorophyll-a and sea surface temperature (SST). These data sets were used for statistical comparisons between measures in situ and satellite estimates looking validate algorithms or develop a comprehensive regional approach empirically. AQUA-MODIS images allowed the simultaneous comparison of two-dimensional water quality (total suspension matter), phytoplankton biomass (chlorophyll-a) variability and physical (temperature). For images of total suspension matter, the generated models showed a good correlation with the field data, allowing quantitative and qualitative analysis. The images of chlorophyll-a showed a consistent correlation with the in situ values of concentration. The algorithms adjusted for these images obtained a correlation coefficient fairly well with the data field in order that the sensor can be having an effect throughout the water column and not just the surface. This has led to a fit between the data of chlorophyll-the integration of the average sampling interval of the entire water column up to the level of the first optical depth, with the data generated from the images. This method resulted in higher values of chlorophyll concentration to greater depths, due to the fact that we are integrating more values of chlorophyll in the water column. Thus we can represent the biomass available in the water column. Images SST and SST measures in situ showed a mean difference DT (SST insitu - SST sat) around -0.14 ° C, considered low, making the results very good. The integration of total suspension matter, chlorophyll-a, the temperature of the sea surface (SST) and auxiliary data enabled the recognition of some of the main ways to fund the continental shelf. The main features highlighted were submerged canyons of rivers Apodi and Açu, some of the lines and beachrocks reefs, structural highs and the continental shelf break which occurs at depths around -60 m. The results confirmed the high potential for use of the AQUA-MODIS images to environmental monitoring of sea areas due to ease of detection of the field two-dimensional material in suspension on the sea surface, temperature and the concentration of chlorophyll-a

Iinterpretação conjunta de dados de GPR e medidas de permeabilidade sobre um análogo de reservatório siliciclástico falhado na bacia de Tucano, no NE do Brasil

It is presented an integrated geophysical investigation of the spatial distribution of faults and deformation bands (DB´s) in a faulted siliciclastic reservoir analogue, located in Tucano Basin, Bahia State, northeastern Brazil. Ground Penetrating Radar (GPR) and permeability measurements allowed the analysis of the influence of DB´s in the rock permeability and porosity. GPR data were processed using a suitable flow parametrization in order to highlight discontinuities in sedimentary layers. The obtained images allowed the subsurface detection of DB´s presenting displacements greater that 10 cm. A good correlation was verified between DB´s detected by GPR and those observed in surface, the latter identified using conventional structural methods. After some adaptations in the minipermeameter in order to increase measurement precision, two approaches to measure permeabilities were tested: in situ and in collected cores. The former approach provided better results than the latter and consisted of scratching the outcrop surface, followed by direct measurements on outcrop rocks. The measured permeability profiles allowed to characterize the spatial transition from DB´s to undeformed rock; variation of up to three orders of magnitude were detected. The permeability profiles also presented quasi-periodic patterns, associated with textural and granulometric changes, possibly associated to depositional cycles. Integrated interpretation of the geological, geophysical and core data, provided the subsurface identification of an increase in the DB´s number associated with a sedimentary layer presenting granulometric decrease at depths greater than 8 m. An associated sharp decrease in permeability was also measured in cores from boreholes. The obtained results reveal that radagrams, besides providing high resolution images, allowing the detection of small structures (> 10 cm), also presented a correlation with the permeability data. In this way, GPR data may be used to build upscaling laws, bridging the gap between outcrop and seismic data sets, which may result in better models for faulted reservoirs

Beachrocks do Rio Grande Do norte: correlação entre os depósitos costeiros e os de zona costa-afora com base na faciologia, petrografia e diagênese

Beachrocks são rochas sedimentares formadas pela cimentação de sedimentos praiais por carbonato de cálcio em especial, calcita e/ou aragonita em zona de estirâncio. A ocorrência dessas rochas é bastante comum em diversas partes do globo, sobretudo em regiões com latitudes inferiores a 40º. O Rio Grande do Norte possui grande quantidade de beachrocks, os quais afloram tanto em regiões costeiras quanto em zona costa-afora. Os depósitos de beachrocks de zona costeira do referido estado têm sido estudados por diversos autores, os quais abordaram os mais variados temas desde o início do século XX. Por outro lado, os depósitos de zona costa-afora apesar de terem sido estudados por poucos autores têm ganhado atenção apenas nos últimos anos. Porém, nenhum trabalho até o presente fez algum tipo de estudo comparativo de cunho geológico entre os corpos de beachrocks presentes em ambas as zonas: costeira e costa-afora. Sendo assim, a presente dissertação teve o intuito de correlacionar os corpos de beachrocks que afloram em zona costeira aos que estão atualmente dispostos em zona costa-afora, próximo a isóbata de 25 m, levando em consideração seus aspectos petrográficos, diagenéticos e sedimentológicos. Para isso, foram percorridos cerca de 260 km de litoral, correspondendo ao trecho entre os municípios de Extremoz e Tibau, em busca de afloramentos de beachrocks. Seções colunares foram confeccionadas e amostras coletadas em estações de amostragem representativas da zona costeira, ao passo que da zona costa-afora apenas seções delgadas foram analisadas. Trabalhos disponíveis na literatura sobre o tema e área em pauta também foram utilizados. A partir dos dados levantados, observou-se que os beachrocks são formados por diferentes camadas ao longo de um perfil vertical. Estas camadas são claramente identificadas em afloramento pela diferença existente na composição, textura e estruturas sedimentares peculiares a cada uma delas. Seções delgadas foram confeccionadas e analisadas a partir de amostras coletadas nas diferentes camadas de diversos afloramentos. Um afloramento foi escolhido como afloramento modelo sendo este o de São Bento do Norte por apresentar a maior espessura de rocha aflorante (1,9 m). Este tem sido muito bem estudado tanto no corrente trabalho quanto em trabalhos de outros autores. A este foram comparados todos os outros afloramentos analisados. A partir da análise micropetrográfica, foram identificadas 03 microfácies para os beachrocks do Rio Grande do Norte, sendo elas: Quartzarenítica (< 2,9% de bioclastos), Quartzarenítica Bioclástica (entre 3 e 9,9% de bioclastos) e Bio-quartzarenítica (> 10% de bioclastos). Associando essas microfácies às análises sedimentológicas realizadas foi possível propor que as microfácies Quartzarenítica e Bio-quartzarenítica foram depositadas em zona de estirâncio enquanto que a microfácies Quartzarenítica Bioclástica foi depositada em zona de face litorânea superior. A história diagenética dos beachrocks estudados é marcada por quatro principais processos: compactação mecânica, cimentação, dissolução e geração de porosidade secundária, e oxidação. Dentre esses, o processo de cimentação é o mais importante, sendo caracterizado por precipitação de cimento de calcita rica em Mg sob cinco morfologias, a saber: cutículas criptocristalinas, franjas prismáticas isópacas, calcita espática microcristalina, calcita espática equante e agregados pseudo-peloidais. Todas estas morfologias foram formadas durante o estágio de eodiagênese, nas zonas freática marinha ativa ou freática meteórica ativa, corroborando assim com a idéia de que beachrocks têm sua litificação completa a pequenas profundidades. Associando as análises microfaciológicas às diagenéticas foi possível sugerir que a sucessão vertical de camadas vista em alguns beachrocks costeiros representam registros de variações de mais alta frequência do nível do mar durante o Holoceno. A partir daí, baseando-se em informações obtidas através de curvas de variação do nível do mar relativo no Holoceno para o Rio Grande do Norte, disponíveis na literatura, e na correlação aqui realizada entre os beachrocks costeiro e aqueles de zona costa-afora, foi possível inferir que estes últimos representam uma antiga linha de costa formada a idades relativas superiores a 7.000 anos A.P

Consumo privado de ansiolíticos benzodiazepínicos e sua correlação com indicadores sociodemográficos nas capitais brasileiras

This work aims to analyze the distribution of anxiolytics and their frequency of consumption in the period of 2010 to 2012, on the Federal District and at other Brazilian cities, as well as evaluating the correlation between such consumption and its demographic, epidemiological, economic and social characteristics for each region of this study. Into the analysis, it was observed that social, economic and cultural factors seem to influence the over-consumption of these drugs in many countries. Based on this, the benzodiazepines (BDZs) have achieved great popularity among members of the medical community and among the general population, mainly because of its safety and effectiveness in controlling symptoms of anxiety, insomnia and convulsions. Concerning the methodology of this work, an ecological study was performed having as sampling Brazilian capitals and as data source the 2010 Population Census, as well as information from IBGE, DATASUS and ANVISA. Still in the case of the methodological procedure, a multiple linear regression was used. Through descriptive analysis, it was demonstrated that the Northern region has the lowest average on consumption of these drugs (being 0.24 DHD in Manaus); meanwhile in the capitals of the Southeast, higher means were identified (reaching 7.29 DHD in Belo Horizonte), with a national average of 3.04 DHD. Among the drugs analyzed, it was found that Alprazolam is the most dispensed by pharmacies and private drugstores, averaging 2.00 DHD for Brazilian capitals. A análise de regressão linear múltipla mostrou que 76% da variação no consumo foi explicada pela variação da densidade populacional (β = 0,310 p = 0,045) e pela percentagem de médicos (β = 0,507 p = 0,016). Therefore, it was concluded that the consumption of anxiolytics of short half-life has been increasing over the years, mainly in the cities of greater population density and with the highest concentration of doctors