48 resultados para contemporary commercial architecture

em Doria (National Library of Finland DSpace Services) - National Library of Finland, Finland


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Den rikt utformade och komplexa hinduiska traditionen har hittills huvudsakligen tecknats av manliga forskare och det är främst manliga religiösa strävanden som har dokumenterats. Detta förhållande och de patriarkala synsätt som styr många auktoritativa heliga texter har bidragit till att skapa intrycket att hinduiska kvinnors religiösa erfarenheter antingen saknas eller är avsevärt begränsade. Denna studie lyfter fram det faktum att ett ökande antal indiska kvinnor inom dagens hinduism axlar publika roller som religiösa ledare. Med sitt framträdande utmanar många av dessa rådande sociala uppfattningar om kvinnors underordnade ställning och främjar därmed en förnyad medvetenhet av urgamla föreställningar om Gud som kvinna. Avhandlingen utforskar fenomenet kvinnliga guruer genom att belysa sjuttio guruers andliga karriär, med särskild fokus på fyra av dem. Några av de frågor som behandlas är följande: På vilket sätt är kvinnliga guruer del av den hinduiska traditionen? Vilka förväntningar ställs på dem? Hur legitimeras deras auktoritet som guruer? Hur handskas guruerna med sina dubbla roller som kvinnor och andliga ledare? Hur återspeglas gudinnans ställning, som i indisk religiositet ofta är central, i kvinnors faktiska verklighet? Bidrar kvinnliga guruer med sitt religiösa engagemang till att nyskapa och förändra den indiska religiösa diskursen och utövningen av religion?

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This problem of hell is a specific form of the problem of evil that can be expressed in terms of a set of putatively incompatible statements: 1. An omnipotent God could create a world in which all moral agents freely choose life with God. 2. An omnibenevolent God would not create a world with the foreknowledge that some (perhaps a significant proportion) of God’s creatures would end up in hell. 3. An omniscient God would know which people will end up in hell. 4. Some people will end up forever in hell. Since the late twentieth century, a number of British and North American philosophical theologians, inspired by C.S. Lewis, have developed a new approach to answering the problem of hell. Very little work has been done to systematize this category of perspectives on the duration, quality, purpose and finality of hell. Indeed, there is no consensus among scholars as to what such an approach should be called. In this work, however, I call this perspective issuantism. Starting from the works of a wide range of issuantist scholars, I distill what I believe to be the essence of issuantist perspectives on hell: hell is a state that does not result in universal salvation and is characterized by the insistance that both heaven and hell must issue from the love of God, an affirmation of libertarian human freedom and a rejection of retributive interpretations of hell. These sine qua non characteristics form what I have labeled basic issuantism. I proceed to show that basic issuantism by itself does not provide an adequate answer to the problem of hell. The issuantist scholars themselves, however, recognize this weakness and add a wide range of possible supplements to their basic issuantism. Some of these supplemented versions of issuantism succeed in presenting reasonable answers to the problem of hell. One of the key reasons for the development of issuantist views of hell is a perceived failure on the part of conditionalists, universalists and defenders of hell as eternal conscious torment to give adequate answers to the problem of hell. It is my conclusion, however, that with the addition of some of the same supplements, versions of conditionalism and hell as eternal conscious torment can be advanced that succeed just as well in presenting answers to the problem of hell as those advanced by issuantists, thus rendering some of the issuantist critique of non-issuantist perspectives on hell unfounded.

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JNK1 is a MAP-kinase that has proven a significant player in the central nervous system. It regulates brain development and the maintenance of dendrites and axons. Several novel phosphorylation targets of JNK1 were identified in a screen performed in the Coffey lab. These proteins were mainly involved in the regulation of neuronal cytoskeleton, influencing the dynamics and stability of microtubules and actin. These structural proteins form the dynamic backbone for the elaborate architecture of the dendritic tree of a neuron. The initiation and branching of the dendrites requires a dynamic interplay between the cytoskeletal building blocks. Both microtubules and actin are decorated by associated proteins which regulate their dynamics. The dendrite-specific, high molecular weight microtubule associated protein 2 (MAP2) is an abundant protein in the brain, the binding of which stabilizes microtubules and influences their bundling. Its expression in non-neuronal cells induces the formation of neurite-like processes from the cell body, and its function is highly regulated by phosphorylation. JNK1 was shown to phosphorylate the proline-rich domain of MAP2 in vivo in a previous study performed in the group. Here we verify three threonine residues (T1619, T1622 and T1625) as JNK1 targets, the phosphorylation of which increases the binding of MAP2 to microtubules. This binding stabilizes the microtubules and increases process formation in non-neuronal cells. Phosphorylation-site mutants were engineered in the lab. The non-phosphorylatable mutant of MAP2 (MAP2- T1619A, T1622A, T1625A) in these residues fails to bind microtubules, while the pseudo-phosphorylated form, MAP2- T1619D, T1622D, Thr1625D, efficiently binds and induces process formation even without the presence of active JNK1. Ectopic expression of the MAP2- T1619D, T1622D, Thr1625D in vivo in mouse brain led to a striking increase in the branching of cortical layer 2/3 (L2/3) pyramidal neurons, compared to MAP2-WT. The dendritic complexity defines the receptive field of a neuron and dictates the output to the postsynaptic cells. Previous studies in the group indicated altered dendrite architecture of the pyramidal neurons in the Jnk1-/- mouse motor cortex. Here, we used Lucifer Yellow loading and Sholl analysis of neurons in order to study the dendritic branching in more detail. We report a striking, opposing effect in the absence of Jnk1 in the cortical layers 2/3 and 5 of the primary motor cortex. The basal dendrites of pyramidal neurons close to the pial surface at L2/3 show a reduced complexity. In contrast, the L5 neurons, which receive massive input from the L2/3 neurons, show greatly increased branching. Another novel substrate identified for JNK1 was MARCKSL1, a protein that regulates actin dynamics. It is highly expressed in neurons, but also in various cancer tissues. Three phosphorylation target residues for JNK1 were identified, and it was demonstrated that their phosphorylation reduces actin turnover and retards migration of these cells. Actin is the main cytoskeletal component in dendritic spines, the site of most excitatory synapses in pyramidal neurons. The density and gross morphology of the Lucifer Yellow filled dendrites were characterized and we show reduced density and altered morphology of spines in the motor cortex and in the hippocampal area CA3. The dynamic dendritic spines are widely considered to function as the cellular correlate during learning. We used a Morris water maze to test spatial memory. Here, the wild-type mice outperformed the knock-out mice during the acquisition phase of the experiment indicating impaired special memory. The L5 pyramidal neurons of the motor cortex project to the spinal cord and regulate the movement of distinct muscle groups. Thus the altered dendrite morphology in the motor cortex was expected to have an effect on the input-output balance in the signaling from the cortex to the lower motor circuits. A battery of behavioral tests were conducted for the wild-type and Jnk1-/- mice, and the knock-outs performed poorly compared to wild-type mice in tests assessing balance and fine motor movements. This study expands our knowledge of JNK1 as an important regulator of the dendritic fields of neurons and their manifestations in behavior.

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Cleavages have been central in understanding the relationship between political parties and voters but the credibility of cleavage approach has been increasingly debated. This is because of decreasing party loyalty, fewer ideological differences between the parties and general social structural change amongst other factors. By definition, cleavages arise when social structural groups recognize their clashing interests, which are reflected in common values and attitudes, and vote for parties that are dedicated to defend the interests of the groups concerned. This study assesses relevance of cleavage approach in the Finnish context. The research problem in this study is “what kind of a cleavage structure exists in Finland at the beginning of the 21st century? Finland represents a case that has traditionally been characterized by a strong and diverse cleavage structure, notable ideological fragmentation in the electorate and an ideologically diverse party system. Nevertheless, the picture of the party-voter ties in Finland still remains incomplete with regard to a thorough analysis of cleavages. In addition, despite the vast amount of literature on cleavages in political science, studies that thoroughly analyze national cleavage structures by assessing the relationship between social structural position, values and attitudes and party choice have been rare. The research questions are approached by deploying statistical analyses, and using Finnish National Election Studies from 2003, 2007 and 2011as data. In this study, seven different social structural cleavage bases are analyzed: native language, type of residential area, occupational class, education, denomination, gender and age cohorts. Four different value/attitudinal dimensions were identified in this study: economic right and authority, regional and socioeconomic equality, sociocultural and European Union dimensions. This study shows that despite the weak overall effect of social structural positions on values and attitudes, a few rather strong connections between them were identified. The overall impact of social structural position and values and attitudes on party choice varies significantly between parties. Cleavages still exist in Finland and the cleavage structure partly reflects the old basis in the Finnish party system. The cleavage that is based on the type of residential area and reflected in regional and socioeconomic equality dimensions concerns primarily the voters of the Centre Party and the Coalition Party. The linguistic cleavage concerns mostly the voters of the Swedish People’s Party. The classic class cleavage reflected in the regional and socioeconomic equality dimension concerns in turn first and foremost the blue-collar voters of the Left Alliance and the Social Democratic Party, the agricultural entrepreneur voters of the Centre Party and higher professional and manager voters of the Coalition Party. The conflict with the most potential as a cleavage is the one based on social status (occupational class and education) and it is reflected in sociocultural and EU dimensions. It sets the voters of the True Finns against the voters of the Green League and the Coalition Party. The study underlines the challenges the old parties have met after the volatile election in 2011, which shook the cleavage structure. It also describes the complexity involved in the Finnish conflict structure and the multidimensionality in the electoral competition between the parties.

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Tässä insinöörityössä selvitettiin mahdollisuuksia parantaa Tapiola-ryhmän Yhtiökokousjärjestelmä-ohjelmiston ominaisuuksia ja tietoturvallisuutta. Järjestelmää käytetään Tapiola-ryhmän vakuutusyhtiöiden yhtiökokouksiin osallistuvien osakkaiden kirjaamiseen ja heidän äänten laskentaan. Tutkimuksen perusteella tehtiin järjestelmän määrittely ja suunnittelu, joiden tuloksena syntyivät toiminnallinen ja tekninen määrittelydokumentaatio, jotka toimivat pohjana uuden Yhtiökokousjärjestelmän toteutukselle. Työ tehtiin Tapiola-ryhmälle Tieto-Tapiola Oy:n tilauksesta. Työn alussa tutkittiin erilaisia mahdollisuuksia toteuttaa järjestelmän ohjelmisto- ja tietokanta-arkkitehtuuri, joiden perusteella määrittelyä ja suunnittelua alettiin toteuttaa. Tutkimuksen perusteella päädyttiin käyttämään Java SE -arkkitehtuuria sovelluksen toteutukseen ja SQL Server -tietokantaa järjestelmän tietovarastona. Valittuihin ratkaisuihin päädyttiin niiden hyvien tietoturvallisuus- ja kertakirjausominaisuuksien takia. Toiminnallisessa määrittelydokumentissa käydään läpi järjestelmälle asetettuja vaatimuksia ja kuvataan sen toiminnot, liiketoimintaluokkamalli, käyttöliittymä ja tulosteet. Lisäksi siinä otetaan kantaa järjestelmän käyttöympäristöön, ulkoisiin tietokantaliittymiin, käyttäjän tunnistautumiseen ja tietoturvallisuuteen sekä käydään läpi sen toiminta käyttäjien näkökulmasta. Toiminnallisen määrittelydokumentin pohjalta luotiin tekninen määrittelydokumentti. Siinä kuvataan järjestelmän ympäristö ja ohjelmisto- sekä tietokanta-arkkitehtuuri yleisellä tasolla. Tämän lisäksi järjestelmän arkkitehtuuria käydään myös tarkemmin läpi sekä kuvataan moduulit ja toiminnot niin tarkasti, että niiden perusteella voidaan toteuttaa koko järjestelmä. Työn tuloksena syntyivät kattava toiminnallinen ja tekninen määrittelydokumentaatio, joissa käydään läpi kaikki järjestelmän toteuttamiseen tarvittavat elementit sillä tarkkuudella, että järjestelmän toteuttaminen voidaan aloittaa.

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The purpose of this thesis was to investigate how and why an art competition was arranged to select pieces for the parliamentary annexe building in Helsinki. There is an emphasis on the cultural production aspects of the research. For the purpose of comparison, the thesis also examines how art acquisition takes place in the cities of Helsinki, Salo and Vantaa, and how the so-called percentage principle has been used in these cities The research method involved thematic interviewing of four persons with central positions on the competition jury. Questions were also sent by e-mail to experts and other people with knowledge of the subject area. Although art competitions have been arranged in Finland for decades, very little relevant literature exists. In addition to the interviews, other relevant literature was also referred to, including parliamentary records. The crucial questions concerned why the art competition for the parliamentary annexe was arranged and whether, indeed, it is possible to compete artistically in this manner. The thesis also examined the relationship between art and architecture and how the best works were selected from the vast range of submissions. The answers were both honest and interesting. The thesis presents a step-by-step analysis of the competition's progress over two stages, and according to the specific rules for such competitions as laid out in Suomen Taiteilijaseura. Strict adherence to the rules of the competition created a number of problems, some of which are also studied. The primary reason for staging a competition was to be as democratic as possible, and eliminating any possibility of nominating a particular artist or artists to realise their own work within the annexe. The competition opened up the possibility to consider various artistic proposals, and no genres were ruled out in advance. This format ensured a good response and a total of 1719 proposals were received, of which six were eventually selected. One conclusion was that open competition may not be the best way to gather artistic proposals in such circumstances, but it is very democratic.

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The present thesis deals with the reception of the celebrity profiles of the MTV3 news current affairs program "45 minuuttia". The target group of the research consists of young adults between the ages from 25 to 34 living in the Helsinki metropolitan area. The research is qualitative and it studies the target group's opinions of the program profiles by the means of a survey and a group interview. In the group interview, the interviewees were also presented sample clips of the program. The results of the survey were analyzed mainly quantitatively. The purpose of the survey results was to map the viewing habits of the target group. In analyzing the results of the group, the interview methods of feedback research and cultural audience research were used. The current thesis was a commissioned research, the purpose of which was to study how interested the young adults are in the program. In addition, the aim was also to find out possible new trends and approaches for the producer of the program. In contrary to the expectations, the reason for the low interest in the profiles seemed to be due to the approach taken to the topics, e.g. the profiled person. By the approach I mean how the person is visually presented or how the person is verbally described. Many people presented in the profiles were regarded as interesting, but at the same time, the way the stories were told was hoped to be more versatile. In addition, a more contemporary visual approach was hoped for. The results also verified the claim that the young adults in general are not interested in the current affair programmes. In addition, these results suggested that in order to obtain more precise information of the viewing preferences of the audience, a more thorough study should be conducted.

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Tässä insinöörityössä tutkittiin alan kirjallisuuden kautta MVC-arkkitehtuuria ja suunnittelumalleja. Työn tavoitteena oli toteuttaa käytännön esimerkki, joka yhdistää MVC-arkkitehtuurin ja suunnittelumallit. Työssä lähdettiin liikkeelle perehtymällä ohjelmistoarkkitehtuuriin ja sen eri muotoihin. Keskeiseksi näistä nousi kerrosarkkitehtuuri, joka on myös MVC-arkkitehtuurin rakenne. Itse MVC ei ole käsitteenä eikä konseptina uusi. Norjalainen Trygve Reenskaug on julkaissut ensimmäiset tutkielmat siitä jo 1970-luvulla. Kirjallisuutta tutkittaessa selvisikin, että MVC on kuitenkin pysynyt suhteellisen muuttumattomana. Lisäksi se on edelleen käytössä etenkin interaktiivisten sovellusten suunnittelutyökaluna. Myös useimmat webtason sovelluskehykset käyttävät MVC-mallia. Toinen tutkimuksen kohteena ollut alue oli suunnittelumallit. Ne ovat hyvin abstraktin tason ratkaisuja yleisimpiin suunnitteluongelmiin. Suunnittelumalleja tutkittaessa huomattiin, että niiden käyttöä suunnittelutyössä rajoittaa niiden rajallinen tuntemus. Lisäksi abstraktin esitystavan niitä voi olla hankala soveltaa. Niiden hyödyntäminen käytännön työskentelyssä vaatiikin hyvin syvällistä ohjelmoinnin ja ohjelmointitekniikoiden tuntemusta. Tämän työn kirjallisuustutkimusta käytettiin hyväksi painoindeksisovelluksessa, joka toteutettiin MVC-arkkitehtuurin rakenteen mukaan suunnittelumalleja apuna käyttäen. Sovelluksen toteuttamista helpotti huomattavasti MVC-rakenteen yleisyys. Käytetyt suunnittelumallitkin löytyivät suositusten perusteella. Käytettyjen ratkaisujen vuoksi ohjelman rakenteesta tuli selkeä ja se on helposti laajennettavissa. Läpikäydyn kirjallisuuden ja toteutetun käytännön esimerkin perusteella voidaan todeta, että arkkitehtuurien ja suunnittelumallien käyttämiseen pitäisi pyrkiä. Niiden avulla saavutetaan ylläpidettäviä, muutossietoisia ja laajennettavia sovelluksia.

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Selostus: Perunalajikkeiden ponsiviljelyllä tuotettujen dihaploidien protoplastien sähköfuusio