20 resultados para Danse macabre
em Université de Lausanne, Switzerland
"Auf die Bühne gezaubert, dass man erstaunt" : cinéma, danse et music-hall au tournant du 20e siècle
Resumo:
In this issue of The EMBO Journal, Chattopadhyay et al (2010) describe a surprising new mechanism for how viral dsRNA detection by the RIG-I/MAVS signalling complex can initiate apoptosis. Independent of its transcriptional function, a pool of interferon regulatory factor (IRF)-3 activated downstream of MAVS can bind to and activate cytosolic Bax, resulting in Bax translocation to the mitochondria and initiation of the intrinsic apoptotic pathway.
