75 resultados para improvements


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Tese de Doutoramento Programa Doutoral em Engenharia Electrónica e Computadores.

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Dissertação de mestrado integrado em Engenharia Civil

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Dissertação de mestrado integrado em Engenharia Civil

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Background: It is expected that, by 2020, 15 million new cases of cancer will occur every year in the world, one million of them in Africa. Knowledge of cancer trends in African countries is far from adequate, and improvements in cancer prevention efforts are urgently needed. The aim of this study was to characterize breast cancer clinically and pathologically at presentation in Luanda, Angola; we additionally provide quality information that will be useful for breast cancer care planning in the country. Methods: Data on breast cancer cases were retrieved from the Angolan Institute of Cancer Control, from 2006 to 2014. For women diagnosed in 2009 (5-years of follow-up), demographic, clinical and pathological information, at presentation, was collected, namely age at diagnosis, parity, methods used for pathological diagnoses, tumor pathological characteristics, stage of disease and treatment. Descriptive statistics were performed. Results: The median age of women diagnosed with breast cancer in 2009 was 47 years old (range 25–89). The most frequent clinical presentation was breast swelling with axillary lymph nodes metastasis (44.9 %), followed by a mass larger than 5 cm (14.2 %) and lump (12.9 %). Invasive ductal carcinoma was the main histologic type (81.8 %). Only 10.1 % of cancer cases had a well differentiated histological grade. Cancers were diagnosed mostly at advanced stages (66.7 % in stage III and 11.1 % in stage IV). Discussion: In this study, breast cancer was diagnosed at a very advanced stage. Although it reports data from a single cancer center in Luanda, Angola it reinforces the need for early diagnosis and increasing awareness. According to the main challenges related to breast cancer diagnosis and treatment herein presented, we propose a realistic framework that would allow for the implementation of a breast cancer care program, built under a strong network based on cooperation, teaching, audit, good practices and the organization of health services. Conclusion: Angola needs urgently a program for early diagnosis of breast cancer.

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Tese de Doutoramento em História - Especialidade de Idade Moderna

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The concept of brewing science is very recent when compared with the history of beer. It began with the microscopic observations of Louis Pasteur and evolved through the last century with improvements in engineering, microbiology, and instrumental analysis. However, the most profound insight into brewing processes only emerged in the past decades through the advances in molecular biology and genetic engineering. These techniques allowed scientists to not only affirm their experiences and past findings, but also to clarify a vast number of links between cellular structures and their role within the metabolic pathways in yeast. This chapter is therefore dedicated to the behavior of the brewing yeast during fermentation. The discussion puts together the recent findings in the core carbon and nitrogen metabolism of the model yeast Saccharomyces cerevisiae and their fermentation performance.

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Dissertação de mestrado em Genética Molecular

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O artigo trata da avaliação preliminar da eficácia do Pais por Inteiro (PApi), uma intervenção em grupo com pais divorciados, implementada com a finalidade de melhorar a adaptação ao divórcio, a coparentalidade e a binuclearidade familiar. Os participantes (n= 16) foram equitativamente distribuídos em um grupo experimental (sujeito a intervenção) e um grupo de controlo. Os grupos mostraram-se semelhantes nas medidas dependentes pré-intervenção. Os resultados evidenciaram uma melhoria entre o pré e pós-teste no ajustamento ao divórcio e na qualidade da coparentalidade no grupo experimental, e uma melhoria no pós-teste no ajustamento também no grupo experimental. Estas melhorias não existiram no grupo de controlo. Estes resultados sugerem a eficácia do PApi em termos do melhor ajustamento pósdivórcio e coparentalidade.

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Current data mining engines are difficult to use, requiring optimizations by data mining experts in order to provide optimal results. To solve this problem a new concept was devised, by maintaining the functionality of current data mining tools and adding pervasive characteristics such as invisibility and ubiquity which focus on their users, providing better ease of use and usefulness, by providing autonomous and intelligent data mining processes. This article introduces an architecture to implement a data mining engine, composed by four major components: database; Middleware (control); Middleware (processing); and interface. These components are interlinked but provide independent scaling, allowing for a system that adapts to the user’s needs. A prototype has been developed in order to test the architecture. The results are very promising and showed their functionality and the need for further improvements.

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Tese de Doutoramento em Ciências da Saúde

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Tese de Doutoramento em Engenharia Biomédica.

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Relatório de estágio de mestrado em Tradução e Comunicação Multilingue

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Dissertação de mestrado em Engenharia Industrial

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Dissertação de mestrado em Bioengenharia