62 resultados para Pro et contra
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Epistemological foundationalism has for centuries attempted to unify all scientific inquiry into the context of one grand science, the first philosophy. One of the most important tasks of this tradition has been to ground all knowledge on absolutely certain foundations. In this master s thesis I ask the following question: To what extent and under what conditions is it possible to achieve absolute certainty in the sense of the attempts of Cartesian foundationalism? By examining how the 20th century philosophers, Edmund Husserl (1859-1938), Hannah Arendt (1906-1975) and Maurice Merleau-Ponty (1908-1961) interpret the epistemological methodology of René Descartes, I claim that the Cartesian achievement of absolute certainty rests on the implicit presupposition of an epistemologically prior form of faith in the world and trust (pistis) in other conscious beings. I show that knowledge is possible only within the context of a common world that is inhabited by several conscious beings that share a common linguistic system. This threefold element is shown to be the bedrock condition for any kind of philosophical inquiry. The main literature sources for this thesis are The Life of the Mind by Hannah Arendt, Le Visible et l invisible by Maurice Merleau-Ponty, Meditationes de Prima Philosophiae by René Descartes and Erfahrung und Urteil by Edmund Husserl.
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The purpose of the research was to study how Finnish lower-stage schools participating in the international network of UNESCO schools, also called the Associated Schools Project (ASP), prepare their students for the future at the level of their school-based curriculums. In the research, the future trends were discussed, and the importance of their consideration in educational practice was explained from a global viewpoint: Based on the examination of today's problematic world state, and development trends characterized by globalization, the challenges and demands set for schooling and education in the future were discussed. Understanding the significance of an individual's action and responsibility was considered to be the central resource for building a more just and sustainable future. The study was grounded on a theoretical model developed by the researcher, which combined the models of Dalin & Rust (1996) and UNESCO (Delors et al. 1996) about future-oriented learning. The model consists of four basic elements of curriculum; "Nature", "Culture", "Myself", and "Others", and four dimension of learning; "Learning to know", "Learning to do", "Learning to live together" and "Learning to be". The model represents the holistic aspect of educational theory, and its aim is to maintain a balance between its different components. The research material composed of ten lower-stage UNESCO schools' school-based curriculums. They were analyzed using the theoretical model by the methology of content analysis. The research results were notably consistent between the different schools. They showed cultural learning and learning concerned with "myself" to be clearly more emphasized than learning referring to nature and other people. In addition, they reflected the central position of subjects, knowledge and skills, thus leaving the development of the pupils' personalities, and particularly learning concerned with living with other people, in a marginal role. The question about whether the schools prepare for the future interms of their curriculums, was discussed in the light of the results. The research offered a way and a model to approach the relationship between education and the future, and to evaluate schools' future-orientation. Based on the results, the schools are suggested to lay more stress on learning concerned with nature and other people, and focus more on developing the mental capasities of their pupils and competencies they need for living with other people. Above all, what the present societies require of schools is education which produces balanced and broadly aware human beings who have the mental strength to face the challenges of the future and abilities to direct it along the lines they desire. Keywords: future, curriculum, content analysis
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The purpose of the present study was to evaluate the effects of Lactobacillus helveticus fermented milk (peptide milk) containing the casein-derived tripeptides Isoleucyl-prolyl-proline (Ile-Pro-Pro) and Valyl-prolyl-proline (Val-Pro-Pro) on blood pressure and vascular function in hypertensive subjects. The peptide milk lowered systolic and diastolic blood pressure in long-term use in hypertensive subjects when blood pressure was measured by using 24-hour ambulatory blood pressure measurement (ABPM). The blood pressure lowering effect was seen with the dose of 50 mg of tripeptides, and a tendency for lowering blood pressure was also observed when the dose was 5 mg. No adverse effects compared to the placebo group were reported or detected in laboratory analysis. The effect of the peptide milk on arterial stiffness was shown using two different methods, the ambulatory arterial stiffness index (AASI) and pulse wave analysis (PWA). According to the AASI, arterial stiffness was significantly reduced in the peptide milk group compared to the baseline level, but the difference was not significant compared to the placebo group. PWA showed that the peptide milk reduced arterial stiffness significantly compared to the placebo group. Endothelium-independent relaxation (nitroglycerin) and endothelium-dependent relaxation (salbutamol) did not differ between the groups. The blood pressure lowering mechanisms of the tripeptides and the kinetics of Ile-Pro-Pro were investigated using spontaneously hypertensive rats (SHR) and Sprague-Dawley rats. Previous studies have suggested that the blood pressure lowering effect of the tripeptides Ile-Pro-Pro and Val-Pro-Pro is based on angiotensin-converting enzyme inhibition, but the present findings did not agree with these previous studies. It was shown in SHR that calcium, potassium and magnesium may also have an important role in attenuating the development of hypertension as part of the peptide milk effect. In addition, the present study suggests indirectly that improved endothelial nitric oxide release capacity is not the mechanism by which peptide milk mediates its favourable circulatory effects. The kinetics of Ile-Pro-Pro were studied using adult Sprague-Dawley rats. The results showed that orally administered Ile-Pro-Pro is absorbed at least partly intact from the gastrointestinal tract. Radiolabelled Ile-Pro-Pro was distributed in different tissues and considerable radioactivity levels were found in tissues related to the renin-angiotensin system (RAS), adrenals, aorta and kidneys. Ile-Pro-Pro does not bind to plasma proteins, and therefore it is possible that its blood pressure lowering effect is mediated by free Ile-Pro-Pro. In conclusion, consumption of the peptide milk lowers blood pressure and reduces arterial stiffness in hypertensive subjects. Ile-Pro-Pro can be absorbed partly intact from the gastrointestinal tract and might accumulate in tissues related to the RAS. The precise blood pressure lowering mechanism of peptide milk remains to be studied.
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The biological function of nitric oxide and its oxidized forms has received a great deal of attention over the past two decades. However much less attention has been focused on the reduced nitric oxide, nitroxyl (HNO). Unlike NO, HNO is highly reactive species and thus it needs to be generated by using donor compounds under experimental conditions. Currently there is only one donor available, Angeli s salt, which releases HNO in a controlled fashion under pysiological conditions. Prior studies have shown the pro-oxidative and cytotoxic potential of Angeli s salt compared to NO donors. The high reactivity of HNO with cysteine thiols is considered to form the biochemical basis for its unique properties compared to other nitrogen oxides. Such thiol modification cold result in disturbances of vital cellular functions and subsequently to death of disturbance sensitive cells, such as neurons. Therefore modification of proteins and lipids was studied in vitro and the potential neurotoxicity was studied in vivo by local infusion of Angeli s salt into the rat central nervous system. The results show that under aerobic in vitro conditions, HNO can, subsequent to autoxidation, cause irreversible oxidative modification of proteins and lipids. These effects are not however seen in cell culture or following infusion of Angeli s salt directly into the rat central nervous tissue likely due to presence of lower oxygen and higher thiol concentration. However, due to high reactivity with thiols, HNO can cause irreversible inactivation of cysteine modification sensitive enzymes such as cysteine proteases papain in vitro and cathepsin B in cell culture. Furthermore it was shown that infusion of HNO releasing Angeli s salt into the rat central nervous system causes necrotic cell death and motor dysfunction following infusion into the lumbal intrathecal space. In conclusion, the acute neurotoxic potential of Angeli s salt was shown to be relatively low, but still higher compared to NO donors. HNO was shown to affect numerous cellular processes which could result in neurotoxicity if HNO was produced in vivo.
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The aim of this paper is to present the evolution of the Francovich doctrine within the European legal order. The first part deals with the gradual development of the ECJ's case law on State liability in damages for breach of EC law. Starting from the seminal Francovich and Brasserie du Pêcheur, the clarification of the criteria set by the Court is attempted with reference to subsequent case law, whereas issues concerning the extent and form of the compensation owned are also mentioned. The second part concerns one of the more recent developments in the field, namely State liability for breaches of Community law attributed to national judiciary. The Court's ruling in Köbler is examined in connection with two other recent judgments, namely Commission v. Italy of 2003 and Kühne & Heitz, as an attempt of the ECJ to reframe its relationships with national supreme courts and appropriate for itself the position of the Supreme Court in the European legal order. The implications on State liability claims by the ruling in Commission v. France of 1997 constitute the theme of the third part, where it is submitted that Member States can also be held liable for disregard of Community law by private individuals within their respected territories. To this extent, Schmidberger is viewed as a manifestation of this opinion, with fundamental rights acquiring a new dimension, being invoked by the States, contra the individuals as a shield to liability claims. Finally, the third part examines the relationship between the Francovich doctrine and the principle of legal certainty and concludes that the solutions employed by the ECJ have been both predictable and acceptable by the national legal orders. Keywords: State liability, damages, Francovich, Köbler, Schmidberger
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This study focuses on the theory of individual rights that the German theologian Conrad Summenhart (1455-1502) explicated in his massive work Opus septipartitum de contractibus pro foro conscientiae et theologico. The central question to be studied is: How does Summenhart understand the concept of an individual right and its immediate implications? The basic premiss of this study is that in Opus septipartitum Summenhart composed a comprehensive theory of individual rights as a contribution to the on-going medieval discourse on rights. With this rationale, the first part of the study concentrates on earlier discussions on rights as the background for Summenhart s theory. Special attention is paid to language in which right was defined in terms of power . In the fourteenth century writers like Hervaeus Natalis and William Ockham maintained that right signifies power by which the right-holder can to use material things licitly. It will also be shown how the attempts to describe what is meant by the term right became more specified and cultivated. Gerson followed the implications that the term power had in natural philosophy and attributed rights to animals and other creatures. To secure right as a normative concept, Gerson utilized the ancient ius suum cuique-principle of justice and introduced a definition in which right was seen as derived from justice. The latter part of this study makes effort to reconstructing Summenhart s theory of individual rights in three sections. The first section clarifies Summenhart s discussion of the right of the individual or the concept of an individual right. Summenhart specified Gerson s description of right as power, taking further use of the language of natural philosophy. In this respect, Summenhart s theory managed to bring an end to a particular continuity of thought that was centered upon a view in which right was understood to signify power to licit action. Perhaps the most significant feature of Summenhart s discussion was the way he explicated the implication of liberty that was present in Gerson s language of rights. Summenhart assimilated libertas with the self-mastery or dominion that in the economic context of discussion took the form of (a moderate) self-ownership. Summenhart discussion also introduced two apparent extensions to Gerson s terminology. First, Summenhart classified right as relation, and second, he equated right with dominion. It is distinctive of Summenhart s view that he took action as the primary determinant of right: Everyone has as much rights or dominion in regard to a thing, as much actions it is licit for him to exercise in regard to the thing. The second section elaborates Summenhart s discussion of the species dominion, which delivered an answer to the question of what kind of rights exist, and clarified thereby the implications of the concept of an individual right. The central feature in Summenhart s discussion was his conscious effort to systematize Gerson s language by combining classifications of dominion into a coherent whole. In this respect, his treatement of the natural dominion is emblematic. Summenhart constructed the concept of natural dominion by making use of the concepts of foundation (founded on a natural gift) and law (according to the natural law). In defining natural dominion as dominion founded on a natural gift, Summenhart attributed natural dominion to animals and even to heavenly bodies. In discussing man s natural dominion, Summenhart pointed out that the natural dominion is not sufficiently identified by its foundation, but requires further specification, which Summenhart finds in the idea that natural dominion is appropriate to the subject according to the natural law. This characterization lead him to treat God s dominion as natural dominion. Partly, this was due to Summenhart s specific understanding of the natural law, which made reasonableness as the primary criterion for the natural dominion at the expense of any metaphysical considerations. The third section clarifies Summenhart s discussion of the property rights defined by the positive human law. By delivering an account on juridical property rights Summenhart connected his philosophical and theological theory on rights to the juridical language of his times, and demonstrated that his own language of rights was compatible with current juridical terminology. Summenhart prepared his discussion of property rights with an account of the justification for private property, which gave private property a direct and strong natural law-based justification. Summenhart s discussion of the four property rights usus, usufructus, proprietas, and possession aimed at delivering a detailed report of the usage of these concepts in juridical discourse. His discussion was characterized by extensive use of the juridical source texts, which was more direct and verbal the more his discussion became entangled with the details of juridical doctrine. At the same time he promoted his own language on rights, especially by applying the idea of right as relation. He also showed recognizable effort towards systematizing juridical language related to property rights.
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Tutkielman tehtävänä on selvittää jumalallisen auktoriteetin (auctoritas divina) ja ihmisen järjen (ratio) välinen suhde Augustinuksen tietoteoriassa. Päälähteinä käytetään kolmea Augustinuksen varhaistuotannon manikealaisvastaista teosta De moribus ecclesiae catholicae et de moribus manichaeorum, De vera religione ja De utilitate credendi. Tutkielman metodina on systemaattinen analyysi. Tutkimustehtävä sisältää alakysymyksiä: Kuinka käsitepari auktoriteetti - järki suhteutuu käsitepariin uskominen (credere) - ymmärtäminen (intellegere)? Mitkä ovat järjen kyvyt, rajat ja tehtävät? Mikä on auktoriteetin tehtävä ja miksi auktoriteetteja tarvitaan? Missä määrin päälähteiden välillä on eroja? Luvussa 2 tarkastellaan sitä uskonnollis-filosofista taustaa, jonka kautta Augustinuksen käsitys auktoriteetin ja järjen suhteesta tulee ymmärrettäväksi. Vaikka Augustinus liittyykin uskon ja ymmärryksen suhteen varhaiskristilliseen traditioon, ei hänen käsitystään voida ymmärtää irrallaan platonilaisesta ja uusplatonilaisesta tietoteoriasta. Augustinuksen tietoteoria muotoutui myös vastauksessa skeptisismiin ja manikealaiseen pseudo-rationalismiin. Pääluvuissa 3, 4 ja 5 käsitellään Augustinuksen käsitystä auktoriteetin ja järjen suhteesta siten, että kussakin pääluvussa keskitytään yhteen päälähteeseen. Loppukatsauksessa (luku 6) kootaan yhteen tutkimuksen tulokset. Augustinuksen klassisesta roomalaisesta kirjallisuudesta lanseeraama käsitepari auktoriteetti - järki liittyy läheisesti toiseen käsitepariin uskominen - ymmärtäminen. Usko perustuu auktoriteettiin ja ymmärrys järkeen. Niin kuin usko edeltää ymmärrystä (credo ut intelligam), samoin auktoriteetti edeltää uskoa. Mutta toisaalta myös ymmärrys edeltää uskoa siinä mielessä, että on ymmärrettävä auktoriteetin ilmoittamat väitelauseet, jotta usko tulisi mahdolliseksi. Tietyssä mielessä myös järki edeltää auktoriteettia, sillä järki arvioi, kuka on uskomisen arvoinen. Ilman auktoriteettiin perustuvaa uskoa ihminen kykenee järjen avulla tajuamaan ainakin yhden totuuden, nimittäin sen, että kaiken epäileminen on mahdotonta. Radikaaleinkin epäilijä on varma ainakin siitä totuudesta, että hän epäilee. Augustinus antaa toisinaan ymmärtää, että ilman auktoriteettia voidaan käsittää myös Jumalan olemassaolo. Toisinaan hän taas opettaa, että tieto Jumalan olemassaolosta perustuu jumalalliseen auktoriteettiin. Ihmisen järki on rajallinen kahdessa mielessä. Ensinnäkin se ei kykene saavuttamaan varmaa tietoa aistimaailman ajallisista asioista. Varma tieto eli ymmärrys kohdistuu vain ikuisiin ja intelligiibeleihin totuuksiin. Toiseksi ihmisen järki on osallinen syntiinlankeemuksesta niin, että totuuden tavoittaminen tulee lopulta mahdottomaksi ilman auktoriteettia. Jumalallinen auktoriteetti on Augustinuksen mukaan Kristuksessa, Raamatussa ja katolisessa kirkossa. Jumalallinen auktoriteetti ilmoittaa pelastushistorian totuudet, joiden kautta ihmisen mieli puhdistuu ja kykenee kohoamaan kohti ikuisia jumalallisia totuuksia. Jumalallisen auktoriteetin ilmoittamat ikuiset totuudet ovat luonteeltaan sellaisia, että niihin on ensin uskottava, jotta ne voitaisiin myöhemmin ymmärtää (credo, quod intelligam). Auktoriteetin tehtävä on johdattaa järkeen ja järjen tehtävä on johtaa ymmärrykseen. Teoksen päälähteet opettavat pääsääntöisesti samalla tavalla käsillä olevasta aiheesta. De moribuksessa painopiste on tosin muita selkeämmin rakkaudessa: rakkaus johtaa tietoteoreettiseen täyttymykseen. De vera religionessa on vahvimpana ajatus luonnollisesta jumalatuntemuksesta. De utilitate credendi keskittyy voimakkaimmin auktoriteettiuskon puolustamiseen. Päälähteiden painotuserot johtuvat niiden erilaisesta luonteesta.
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Tämä pro gradu -tutkielma tarjoaa sujuvan suomenkielinen käännöksen Hymnien kirjan (1QH) yhteisöllisistä hymneistä. Käännökseni perustuu uuteen 1QH:n tieteelliseen editioon (DJD 2009). Editiossa on hyödynnetty käsikirjoituksen materiaalisen rekonstruktion tuloksia, uusia lukutapoja ja tekstiä on täydennetty muiden Hymnien kirjan käsikirjoitusten avulla. Vertailen omaa käännöstäni García Martínezin ET Tigchelaarin (1997), Abeggin et al. (2005), sekä Newsomin (2009) käännöksiin. Käännän yhteensä 14 hymniä, jotka olen otsikoinut itsenäisesti. 1950-1960-luvuilla kehitetyt teoriat Hymnien kirjan hymnien luokittelusta, käytöstä ja kirjoittajasta ovat dominoineet Hymnien kirjan tutkimusta 2010-luvulle asti. Hyödynnän tässä tutkielmassa Hymnien kirjan tutkimuksessa vakiintunutta hymnien jaottelua opettajan hymneihin ja yhteisöllisiin hymneihin. Hymnien jaottelu on kyseenalaistettu viimeaikaisessa tutkimuksessa, mutta vallitsevan tutkimustilanteen valossa näyttää siltä, että jaottelu on edelleen käyttökelpoinen. Kuitenkin molempien ryhmien määritelmiä ja ryhmien suhdetta toisiinsa on tutkimuksessa tarkennettu. Hymnien luokittelua koskevan uuden teorian, samoin kuin eri Hymnien kirjan käsikirjoitusten suhdetta koskevan teorian puuttuminen, ovat tämän hetkisiä haasteita Hymnien kirjan tutkimuksessa. Luvussa neljä tarkastelen, voisiko Hymnien kirja olla osa laajempaa genreä, jonka nimesin Hodajot-kirjallisuudeksi. Tämän laajemman genren olemassaolo saattaisi selittää yhteisöllisten hymnien moninaisuuden sekä Hymnien kirjan käsikirjoitusten väliset erot hymnien määrässä ja järjestyksessä. Hodajot-kirjallisuuteen voidaan laskea kuuluvaksi Hymnien kirjan käsikirjoitukset (1QH, 1QHb, 4QHa f), Hymnien kirjan kaltaiset tekstit (4Q433,4Q433a, 4Q440, 4Q440a) ja 17 Hymnien kirjaa muistuttavaa käsikirjoitusta. Tähän genreen kuuluvista hymneistä aina osa valikoitui erilaisiin Hymnien kirjankin käsikirjoituksiin. Erityisesti käsikirjoitus 4QHa todistaa, että yhteisöllisistä hymneistä oli olemassa myös erilaisia kokoelmia kuin käsikirjoituksen 1QH kokoelma. Esitän luvussa 4.2. kritiikkiä aiempaa tutkimusta kohtaan, jossa käsikirjoituksen 4QHa hymnijärjestystä käytetään todisteena käsikirjoituksen 1QHa yhteisöllisten hymnien editoinnista. Lisäksi ehdotan, että yksittäisten yhteisöllisten hymnien redaktion tutkiminen saattaisi tuoda lisää valoa Hodajot-kirjallisuus -teoriaan. Luvussa kuusi tarkastelen erilaisia yhteisöllisiä hymnejä profetian näkökulmasta. Tutkimukseni perustuu uuteen kuvaan Toisen temppelin ajan profetiasta. Profetian ytimenä nähdään jumalallisen tiedon vastaanottaminen ilmestyksen avulla. Hymnien kirjassa profetia on nk. ilmoitettua viisautta. Koska kattavaa tutkimusta profetiasta Hymnien kirjassa ei ole, ei aikaisemmassa tutkimuksessa ole kiinnitetty huomiota moniin klassisiin profetiaan liittyviin termeihin, joita yhteisöllisissä hymneissä esiintyy. Klassisten profetiaan liittyvien termien ja ilmoitetun viisauden esiintyminen samassa tekstissä puhuu sen puolesta, että yhteisöllisissä hymneissä ilmoitettu viisaus todella nähtiin profetiana. Aikaisemmassa tutkimuksessa on keskusteltu Hymnien kirjan didaktisesta funktiosta. Tutkimukseni perusteella yksi yhteisöllisten hymnien didaktinen funktio on se, että ne opettavat yhteisön jäsenelle hänen identiteetistään suhteessa profetiaan.
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Kielet ruotsi, latina ja suomi. Typis impr. 1924-1926.
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Suomessa vuosina 1901-1930 julkaistun eläintieteellisen kirjallisuuden bibliografia.
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Using data from 2.9 fb-1 of integrated luminosity collected with the CDF II detector at the Tevatron, we search for resonances decaying into a pair of on-shell gauge bosons, WW or WZ, where one W decays into an electron and a neutrino, and the other boson decays into two jets. We observed no statistically significant excess above the expected standard model background, and we set cross section limits at 95% confidence level on G* (Randall-Sundrum graviton), Z′, and W′ bosons. By comparing these limits to theoretical cross sections, mass exclusion regions for the three particles are derived. The mass exclusion regions for Z′ and W′ are further evaluated as a function of their gauge coupling strength.
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Using data from 2.9/fb of integrated luminosity collected with the CDF II detector at the Tevatron, we search for resonances decaying into a pair of on-shell gauge bosons, WW or WZ, where one W decays into an electron and a neutrino, and the other boson decays into two jets. We observed no statistically significant excess above the expected standard model background, and we set cross section limits at 95% confidence level on G*(Randall-Sundrum graviton), Z', and W' bosons. By comparing these limits to theoretical cross sections, mass exclusion regions for the three particles are derived. The mass exclusion regions for Z' and W' are further evaluated as a function of their gauge coupling strength.
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Abstract (A journey through Danish literature translated into Finnish after 1945): Nearly 80 per cent of all literary translations from Danish into Finnish are done after the Second World War. These translations are obviously only a small selection of the Danish national literature, but nevertheless capture important trends and currents in it. Based on a selection of translated works, the article allows a broad introduction to Danish literature available in Finnish. It focuses on children's and youth literature, feminist literature and realistic, magic and civilization critical novels.