53 resultados para Rubén Darío

em Archivo Digital para la Docencia y la Investigación - Repositorio Institucional de la Universidad del País Vasco


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1 carta (mecanografiada) ; 225x160mm. Ubicación: Caja 1 - Carpeta 45

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Duración (en horas): De 11 a 20 horas. Nivel educativo: Grado

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Duración (en horas): De 11 a 20 horas.Nivel educativo: Grado

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Ponencia presentada y defendida en las XIV Jornadas Hispano-Lusas de Gestión Científica celebradas en las Azores en febrero de 2004.

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Background: Malignancies arising in the large bowel cause the second largest number of deaths from cancer in the Western World. Despite progresses made during the last decades, colorectal cancer remains one of the most frequent and deadly neoplasias in the western countries. Methods: A genomic study of human colorectal cancer has been carried out on a total of 31 tumoral samples, corresponding to different stages of the disease, and 33 non-tumoral samples. The study was carried out by hybridisation of the tumour samples against a reference pool of non-tumoral samples using Agilent Human 1A 60- mer oligo microarrays. The results obtained were validated by qRT-PCR. In the subsequent bioinformatics analysis, gene networks by means of Bayesian classifiers, variable selection and bootstrap resampling were built. The consensus among all the induced models produced a hierarchy of dependences and, thus, of variables. Results: After an exhaustive process of pre-processing to ensure data quality–lost values imputation, probes quality, data smoothing and intraclass variability filtering–the final dataset comprised a total of 8, 104 probes. Next, a supervised classification approach and data analysis was carried out to obtain the most relevant genes. Two of them are directly involved in cancer progression and in particular in colorectal cancer. Finally, a supervised classifier was induced to classify new unseen samples. Conclusions: We have developed a tentative model for the diagnosis of colorectal cancer based on a biomarker panel. Our results indicate that the gene profile described herein can discriminate between non-cancerous and cancerous samples with 94.45% accuracy using different supervised classifiers (AUC values in the range of 0.997 and 0.955).

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[ES] La importancia de las percepciones de la dirección de la empresa ante la exportación puede afectar de manera significativa al comportamiento exportador de las pymes. En concreto, este aspecto puede incidir sobre el hecho de comenzar una política de exportación en la empresa, así como en políticas de consolidación de dichas exportaciones. El trabajo presentado analiza empíricamente estos dos hechos. En primer lugar en qué medida la percepción de la dirección ante la exportación afecta al hecho de comenzar la exportación. En segundo lugar, en caso de ya ser pymes exportadoras, se estudian qué percepciones directivas ayudan a consolidar dicho compromiso exportador. Para ello se desarrollan y validan ciertas escalas que miden la percepción de las ventajas y las barreras a la exportación mediante el empleo de ecuaciones estructurales. Ambos estudios se efectúan teniendo en cuenta la condición de familiar o no de las pymes objeto de estudio, con el fin de efectuar un análisis exploratorio sobre la potencial incidencia de este hecho.

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[ES] Este trabajo tiene como objetivo presentar los principales resultados de un estudio que pretende acercarse a la realidad de las pequeñas y medianas empresas riojanas, tanto familiares como no familiares, ya que son mayoría abrumadora en la Comunidad. Se ha realizado un análisis descriptivo de algunos aspectos relevantes de la gestión de los recursos humanos como la formación y el desarrollo de sus trabajadores y directivos, la estabilidad laboral y la estructura de propiedad. En el presente trabajo ofrecemos los principales resultados con respecto a estas cuestiones, esbozando una descripción y valoración de estas empresas, así como un perfil de sus percepciones principales en relación a las cuestiones analizadas.

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[EN] This research provides a useful framework for identifying a small firms’ propensity to engage in entrepreneurial orientation. We examine the impact of the Entrepreneurial Orientation (EO) as a main resource and capability on small firm’ growth. The growth seems to come out as an important demonstration of the entrepreneurial orientation of small firms (Davidsson, 1989; Green and Brown, 1997; Janney and Gregory, 2006). Thus, this research builds on prior conceptual research that suggests a positive integration between entrepreneurial orientation and resource-based view. In the first instance, the research will focus on reviewing literature in the emerging area of entrepreneurial orientation as it applies to growth oriented small firms and resource-based view of the firm. Secondly, an empirical study was developed based on a stratified sample of small firms of manufacturing industry. Data were submitted to a multivariate statistical analysis and a linear regression model was performed in order to predict the influence of the resources and capabilities on small firms’ growth. In this sense, we consider the construct growth as a dependent variable and the ones relates with resources and capabilities (entrepreneur resources, firm resources, networks and EO) as independent variables. The research results suggest a set of resources and capabilities that promote the growth of the small firms. Also, the EO seems to have a predictive value on growth. Explaining variables related with resources and capabilities and EO were identified as essential in growth oriented small firms. It was still possible to conclude that the entrepreneurial firms which grew seem to have resources and develop more capabilities and take advantage in the search for those competences. This attitude reflects on the EO of the firm. This study has important implication for both researchers and practitioners. It highlights the necessity of firms to develop superior EO of all their members and also to invest on better resources and consequently superior capabilities as a way of reaching higher levels of growth. While previous authors have attempted to analyse certain aspects of this process (linkage between entrepreneurial orientation and growth), this research developed a framework that combines these and others factors (resource-based view) pertinent to growth oriented small firms. The results support the necessity to identify explicative variables of multiple levels to explain the growth of small firms. The adoption of an entrepreneurial orientation as an indispensable variable to the growth oriented small firms seems pertinent.

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Helburuak: Liburu hau Telekomunikazio Ingeniaritza Titulazioan enborrezkoa den Dispositiboen Elektronika irakasgaian erabiltzen da. Ikasleek elektronikarekin duten lehenengo harremana hau izaten denez, irakasgaiaren helburu nagusia oinarrizko osagaien ezaugarriak eta funtzionamenduaren printzipioak ezagutaraztea da. Norentzat izan daiteke baliagarria: Testua Ingeniaritza Eskolako Lehenengo Ikasturteko ikasleentzat bereziki prestatu da, baina dispositiboen funtzionamendua eta anplikazio-sistema sinpleak azaltzen dituenez, oso baliagarria gerta daiteke, orobat, edozein maila eta titulazioko Elektronika-ikasleentzat -edota ikasle horiei irakatsi behar dietenentzat.

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Helburuak: Liburu honek Gailuen Elektronika irakasgaian azken urteotan egin diren azterketak jasotzen ditu. Hortaz, ikasleek azterketak prestatzeko eta, oro har, elektronika ikasteko oso baliagarritzat jotzen dugu. Irakasgaiaren helburu nagusia diren oinarrizko osagaien ezaugarriak eta funtzionamenduaren printzipioak lantzen dira. Norentzat izan daiteke baliagarria: Testua Ingeniaritza Eskolako Lehenengo Ikasturteko ikasleentzat bereziki prestatu da, baina gailuen funtzionamendua eta anplikazio-sistema sinpleak aztertzen dituzten ariketak jasotzen dituenez, oso baliagarria gerta daiteke, orobat, edozein maila eta titulazioko Elektronika-ikasleentzat -edota ikasle horiei irakatsi behar dietenentzat.

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Helburuak: Material hau, Telekomunikazio Ingeniaritza Titulazioan enborrezkoa den Oinarrizko Elektronika Laborategia I (OEL I) irakasgaian erabiltzen da. Ikasleak laborategiarekin duen lehenengo harremana izaten denez, irakasgaiaren helburu nagusia Elektronika laborategietan oinarrizkoak diren osagaiak, sorgailuak eta neurgailuak ezagutzea da. Norentzat izan daiteke baliagarria: Testuak, Ingeniaritza Eskolako Lehenengo Ikasturteko ikasleentzat bereziki prestatu badira ere, lantzen diren kontzeptuak oinarrizkoak direnez, baliagarriak gerta daitezke, oro har, Elektronikan lehenengo urratsak egiten ari direnentzat -edota hauei irakatsi behar dietenentzat.

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6 p. Paper of the 17th Conference on Sensors and Their Applications held in Dubrovnik, Croatia. Sep 16-18, 2013

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This paper describes Mateda-2.0, a MATLAB package for estimation of distribution algorithms (EDAs). This package can be used to solve single and multi-objective discrete and continuous optimization problems using EDAs based on undirected and directed probabilistic graphical models. The implementation contains several methods commonly employed by EDAs. It is also conceived as an open package to allow users to incorporate different combinations of selection, learning, sampling, and local search procedures. Additionally, it includes methods to extract, process and visualize the structures learned by the probabilistic models. This way, it can unveil previously unknown information about the optimization problem domain. Mateda-2.0 also incorporates a module for creating and validating function models based on the probabilistic models learned by EDAs.