The Health Effects of Climate Change: A Survey of Recent Quantitative Research

44 p.

Moral Hazard and the Internal Organization of Joint Research

Revised 2006-06

Emaús, una organización de acción social

[ES] Emaús Bilbao Sociedad Cooperativa, es una entidad de Economía Social y Solidaria para la inserción sociolaboral, dedicada a la gestión integral de residuos sólidos urbanos (RSU), con sede en Bilbao y que desarrolla esta actividad en Bizkaia.

Towards complex system design and management in the engineering domain – the smart grid challenge

This is an Author's Accepted Manuscript of an article published in “Emergence: Complexity and Organization”, 15 (2), pp. 14-22 (2013), copyright Taylor & Francis.

Global Self-Organization of the Cellular Metabolic Structure

Background: Over many years, it has been assumed that enzymes work either in an isolated way, or organized in small catalytic groups. Several studies performed using "metabolic networks models'' are helping to understand the degree of functional complexity that characterizes enzymatic dynamic systems. In a previous work, we used "dissipative metabolic networks'' (DMNs) to show that enzymes can present a self-organized global functional structure, in which several sets of enzymes are always in an active state, whereas the rest of molecular catalytic sets exhibit dynamics of on-off changing states. We suggested that this kind of global metabolic dynamics might be a genuine and universal functional configuration of the cellular metabolic structure, common to all living cells. Later, a different group has shown experimentally that this kind of functional structure does, indeed, exist in several microorganisms. Methodology/Principal Findings: Here we have analyzed around 2.500.000 different DMNs in order to investigate the underlying mechanism of this dynamic global configuration. The numerical analyses that we have performed show that this global configuration is an emergent property inherent to the cellular metabolic dynamics. Concretely, we have found that the existence of a high number of enzymatic subsystems belonging to the DMNs is the fundamental element for the spontaneous emergence of a functional reactive structure characterized by a metabolic core formed by several sets of enzymes always in an active state. Conclusions/Significance: This self-organized dynamic structure seems to be an intrinsic characteristic of metabolism, common to all living cellular organisms. To better understand cellular functionality, it will be crucial to structurally characterize these enzymatic self-organized global structures.

What happened during the climate change negotiations in Copenhagen 2009?

4 p.

Low Climate Stabilisation under Diverse Growth and Convergence Scenarios

4 p.

The long road of climate negotiations: From Kyoto to Paris stopping over in Doha

4 p.

The adoption of ecosystem-based adaptation in the international climate agenda

4 p.

Is the current EU climate instrument mix adequate?

4 p.

Warning to navigators: IPCC report on climate change mitigation

6 p.

Effects of Climate Change on the European Nuclear Power Sector

4 p.

The Cancun Climate Summit: a Moderate Success

4 p.

The Health Impacts of Climate Change: A Study of Cholera in Tanzania

27 p.

Impacts of Climate Change on European Critical Infrastructures: The Case of the Power Sector

23 p.