La consommation du vin en Grèce ancienne: idéalisation et réalité

Forma parte del dossier "Penser les banquets grec et romain, Entre représentations et pratiques". Actes de la table ronde Le banquet dans l'Antiquité 6 janvier 2007, Institut national d'histoire de l'art - Paris. Coordinado por Robin Nadeau

Usage of substances and their dosage regimes in pharmacological animal models of schizophrenia

Background: Contrary to what is generally thought schizophrenia is a very common mental health issue. For this, several animal models are used to assess the illness in order to develop a definitive. The most widely spread paradigm is the use of pharmacological models. Aim: The aim of this review is to display which are the most used insults for the assessment of social behaviour related negative symptoms in animal models as well as to ascertain which is the most adequate regime. Design: Literature review. Methods: PubMed database was used for this article by the search of the indexed “schizophrenia”, “animal models”, “social behaviour” and “negative symptoms” descriptors. With the exception of a single article due to it value this review is based on articles from 10 years onwards. Besides, only clinical trials and reviews written in English or Spanish and that had laboratory rodents as target population were accepted. Results: The studies assessed agree that pharmacological models (specially those regarding the NMDA receptor antagonists) are a valuable means for the experimental investigation of negative symptoms in schizophrenia with the necessity to emphasise that only some negative symptoms (anhedonia and social interaction, mainly) can be experimentally assessed. Conclusions: There is not enough evidence regarding the fours aspects of this review. PCP, Ketamine or MK-801 in sub-acute dosage regimes are currently the most indicated insults to mimic schizophrenic symptoms in rodents, although further research in needed, albeit other substances are valuable as well. (In English language exclusively)

Determination of drugs used in combined cardiovascular therapy

Cardiovascular diseases are nowadays the first cause of mortality worldwide, causing around the 30% of global deaths each year. The risk of suffering from cardiovascular illnesses is strongly related to some factors such as hypertension, high cholesterol levels, diabetes, obesity The combination of these different risk factors is known as metabolic syndrome and it is considered a pandemic due to the high prevalence worldwide. The pathology of the disorders implies a combined cardiovascular therapy with drugs which have different targets and mechanisms of action, to regulate each factor separately. The simultaneous analysis of these drugs turns interesting but it is a complex task since the determination of multiple substances with different physicochemical properties and physiological behavior is always a challenge for the analytical chemist. The complexity of the biological matrices and the difference in the expected concentrations of some analytes require the development of extremely sensitive and selective determination methods. The aim of this work is to fill the gap existing in this field of the drug analysis, developing analytical methods capable of quantifying the different drugs prescribed in combined cardiovascular therapy simultaneously. Liquid chromatography andem mass spectrometry (LCMS/MS) has been the technique of choice throughout the main part of this work, due to the high sensitivity and selectivity requirements.

Review: Trans-forming beef to provide healthier fatty acid profiles

[EN]Trans fatty acids are found naturally in foods, particularly in those derived from ruminant animals, such as beef and dairy cattle. Over the past few decades, human consumption of trans fatty acids has increased, but this has been mainly from products containing partially hydrogenated vegetable oils. The correlation of trans fatty acid consumption with diseases such as coronary heart disease has been cause for concern, and led to recommendations to reduce their consumption. Trans fatty acids, however, have differing effects on human health. Therefore, in foods produced from ruminant animals, it is important to know their trans fatty acid composition, and how to enrich or deplete fatty acids that have positive or negative health effects. This review will cover the analysis of trans fatty acids in beef, their origin, how to manipulate their concentrations, and give a brief overview of their health effects.

Neurotransmitter signaling in the pathophysiology of microglia

Erratun publicado en Frontiers in Cellular Neuroscience 7 : (2013) // Article ID 107

Patrón del comportamiento alimentario en escolares

[ES] En la edad escolar se adquieren los hábitos alimentarios que se seguirán, probablemente, durante gran parte de la vida. Objetivos: Conocer y valorar cualitativa y cuantitativamente la dieta semanal de un grupo de escolares y observar las diferencias de ingesta en los días escolares y los del fin de semana. El consumo en raciones de alimentos es más adecuado en los niños con normopeso y en los días escolares. Es precisa una educación nutricional de los niños y su entorno.

Consumo de alimentos ricos en azúcar-sal en niños de Las Arenas (Getxo, Bizkaia) por grupos de edad

[ES] El aumento del consumo de grasas y carbohidratos, así como dulces, refrescos, productos industriales y snacks, junto con la disminución de la ingesta de alimentos saludables, y el sedentarismo en los niños, infl uyen en su salud. Hay que prestar especial atención a alimentos que forman parte del estilo de vida actual: “snack”, dulces, bollería o picoteo entre comidas por sus importantes repercusiones.

Análisis de consecuencias de un escape de metanol en un establecimiento afectado por el RD 1254/1999

[ES]El presente trabajo se centra en el RD 1254/1999, decreto que obliga a aquellos establecimientos que trabajan con sustancias peligrosas y pueden ocasionar accidentes graves con consecuencias en el exterior (nube tóxica, explosión, incendio, radiación, etc.) a hacer un análisis de riesgo de los mencionados accidentes. En base a este análisis se programan los planes de autoprotección así como los planes de emergencia exterior y se establecen los sistemas de gestión de la seguridad. Se estudia un caso práctico en el que se elabora el Análisis de Riesgo de una planta en la que se almacena metanol, y se calculan las distancias a las que llegarían las consecuencias dañinas en caso de accidentes con el metanol.

Participación ciudadana, patrimonio cultural y museos: entre la teoría y la praxis

Cap. 1. La Nueva Museología, el patrimonio cultural y la participación ciudadana a debate. Iñaki Arrieta Urtizberea Cap. 2. Museos: del público al ciudadano. Rafael Azuar Ruiz Cap. 3. Los públicos y lo público. De mutismos, sorderas, y de diálogos sociales en museos y espacios patrimoniales. Luz Maceira Ochoa Cap. 4. La restitution du patrimoine: un rôle pour le musée? Études de cas dans les communautés innues du Québec et du Labrador (Canada). Élise Dubuc Cap. 5. El museo de territorio y sociedad, ¿una utopía? el caso del Museo Industrial del Ter. Carles García Hermosilla Cap. 6. El ecomuseo del río Caicena (Almedinilla-Córdoba): un proyecto de desarrollo rural desde el patrimonio histórico-natural, ¿y la participación ciudadana? Ignacio Muñiz Jaén Cap. 7. Mé-tisser les mémoires. Musées indiens du nordeste brésilien. Martin Soares Cap. 8. El patrimonio como proceso social. Intervención, desarrollo y consumo del patrimonio minero en Andalucía. Macarena Hernández Ramírez y Esteban Ruiz Ballesteros Cap. 9. Legislación patrimonial, intervención pública y participación ciudadana en la declaración de un conjunto histórico. Iñaki Arrieta Urtizberea Cap. 10. El castillo de Montsoriu. La participación de la sociedad civil. Joaquim Mateu Gasquet Cap. 11. El patrimonio cultural; espacio de encuentro. Daniel Arnesio Lara Montero

Citocinas proinflamatorias: participación en la modulación de la actividad del melanoma experimental B16

252 p. : il.