319 resultados para Pérez Pulido, M.
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Gaur egun Twitter moduko mikroblogintza aplikazioak zalantzak argitzeko gero eta gehiago erabiltzen dira. Erabiltzaileak laguntza eskaera adierazi eta sare sozialaren bidez bere kontaktuei helarazi egiten zaie. Erabiltzaileak galdera eta erantzunen kudeaketa sare sozial nahaste baten barruan egin beharko du. Proiektuaren helburu nagusia mikroblogintza plataformetako kanala programazio lengoaien IDEen barruan bateratzea da, modu honetan laguntza eskatzeko prozesua IDEetan bertan kudeatzeko.
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[ES] La documentación de este proyecto ha servido como base para la realización de los siguientes proyectos y artículos:
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We extend the classic Merton (1969, 1971) problem that investigates the joint consumption-savings and portfolio-selection problem under capital risk by assuming sophisticated but time-inconsistent agents. We introduce stochastic hyperbolic preferences as in Harris and Laibson (2013) and find closed-form solutions for Merton's optimal consumption and portfolio selection problem in continuous time. We find that the portfolio rule remains identical to the time-consistent solution with power utility and no borrowing constraints. However,the marginal propensity to consume out of wealth is unambiguously greater than the time-consistent, exponential case and,importantly, it is also more responsive to changes in risk. These results suggest that hyperbolic discounting with sophisticated agents offers promise for contributing to explaining important aspects of asset market data.
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421 p. (Bibliogr.: 375-421
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[ES] Tumba megalítica compuesta por 8 losas (6 en la cámara, una de ellas caída originalmente y 2 en el corredor). El tamaño de la cámara es de unos 2 x 2,5 metros que se encuentra en un morcuero de unos 10 metros de diámetro.
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XX1 CUIEET - Congreso Universitario de Innovación Educativa en las Enseñanzas Técnicas, Valencia, 2013.
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Idazleen nahia, esatariaren lehentasunak eta antolaketa mugaketak kontuan izanik, helburu anitzeko eredu bat zehaztea da, horrela Osakidetzako erietxe konkretu bateko jarduera zehaztu ahal izango dugu eta beraz, baita aurrekontuaren esleipena. Aldi berean, aurrekontu zuzkidura doituz, zentroaren baliabideen erabilpenaren efizientzia azter dezakegu eta orokorrean, zentroaren osasun-laguntzen emaitzak hobetzen lagundu dezakete.
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460 pgs.
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This paper presents new results on the welfare e¤ects of third-degree price discrimination under constant elasticity demand. We show that when both the share of the strong market under uniform pricing and the elasticity di¤erence between markets are high enough,then price discrimination not only can increase social welfare but also consumer surplus.
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Duración (en horas): Ms de 50 horas. Destinatario: Estudiante y Docente
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[EN] Neurodegeneration together with a reduction in neurogenesis are cardinal features of Alzheimer’s disease (AD) induced by a combination of toxic amyloid-β peptide (Aβ) and a loss of trophic factor support. Amelioration of these was assessed with diverse neurotrophins in experimental therapeutic approaches. The aim of this study was to investigate whether intranasal delivery of plasma rich in growth factors (PRGF-Endoret), an autologous pool of morphogens and proteins, could enhance hippocampal neurogenesis and reduce neurodegeneration in an amyloid precursor protein/presenilin-1 (APP/PS1) mouse model. Neurotrophic and neuroprotective actions were firstly evident in primary neuronal cultures, where cell proliferation and survival were augmented by Endoret treatment. Translation of these effects in vivo was assessed in wild type and APP/PS1 mice, where neurogenesis was evaluated using 5-bromodeoxyuridine (BdrU), doublecortin (DCX), and NeuN immunostaining 5 weeks after Endoret administration. The number of BrdU, DCX, and NeuN positive cell was increased after chronic treatment. The number of degenerating neurons, detected with fluoro Jade-B staining was reduced in Endoret-treated APP/PS1 mice at 5 week after intranasal administration. In conclusion, Endoret was able to activate neuronal progenitor cells, enhancing hippocampal neurogenesis, and to reduce Aβ-induced neurodegeneration in a mouse model of AD.
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[EU]Master bukaerako proiektu honetan, SNOMED CT sare semantikoa euskaratzeko aplikazioaren lehenengo urratsak azaltzen ditugu. Horretarako, SNOMED CTren sakoneko analisia egin dugu, eta bio-zientzien domeinuko euskarazko baliabideak aztertu ditugu. Aplikazioaren diseinu osoa egin dugu, euskarazko ordainak lortzeko algoritmo bat definituz. Algoritmo horren lehenengo urratsa izan da inplementatu duguna, hiztegi espezializatuen parekatzeari dagokiona, alegia. Aplikazioaren hastapen hauetan emaitza itxaropentsuak lortu ditugu.
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9 p.
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[ES] La calificación crediticia externa es un elemento clave para el buen fin de las operaciones de titulización. No obstante, las agencias de calificación han sido objeto de una intensa controversia, cuestionándose su fiabilidad y objetividad. En este trabajo abundamos en esta cuestión, analizando la distribución de los ratings otorgados a las emisiones de bonos de titulización llevadas a cabo en España (1993-2011), uno de los países ms activos en cuanto al volumen de emisiones, llegaron a ocupar el segundo puesto a nivel europeo y el tercero a nivel mundial. Aportamos evidencia sobre ciertas anomalías entre las que cabe destacar la estructura oligopolística del mercado del rating, la fragilidad desde una perspectiva histórica de las calificaciones otorgadas, y la existencia de patrones no homogéneos en la elección de la agencia de calificación, tanto si se tiene en cuenta la sociedad gestora, como el colateral de respaldo.
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The role of Na+ fluxes through voltage-gated sodium channels in the regulation of sperm cell function remains poorly understood. Previously, we reported that several genes encoding voltage-gated Na+ channels were expressed in human testis and mature spermatozoa. In this study, we analyzed the presence and function of the TTX-resistant VGSC a subunit Na(v)1.8 in human capacitated sperm cells. Using an RT-PCR assay, we found that the mRNA of the gene SCN10A, that encode Na-v1.8, was abundantly and specifically expressed in human testis and ejaculated spermatozoa. The Na-v1.8 protein was detected in capacitated sperm cells using three different specific antibodies against this channel. Positive immunoreactivity was mainly located in the neck and the principal piece of the flagellum. The presence of Na-v1.8 in sperm cells was confirmed by Western blot. Functional studies demonstrated that the increases in progressive motility produced by veratridine, a voltage-gated sodium channel activator, were reduced in sperm cells preincubated with TTX (10 mu M), the Na-v1.8 antagonist A-803467, or a specific Na-v1.8 antibody. Veratridine elicited similar percentage increases in progressive motility in sperm cells maintained in Ca2+-containing or Ca2+-free solution and did not induce hyperactivation or the acrosome reaction. Veratridine caused a rise in sperm intracellular Na+, [Na+](i), and the sustained phase of the response was inhibited in the presence of A-803467. These results verify that the Na+ channel Na-v1.8 is present in human sperm cells and demonstrate that this channel participates in the regulation of sperm function.