Lucerne biology and genetic improvement - an analysis of past activities and future goals in Australia

Breeding methodologies for cultivated lucerne (Medicago sativa L.), an autotetraploid, have changed little over the last 50 years, with reliance on polycross methods and recurrent phenotypic selection. There has been, however, an increase in our understanding of lucerne biology, in particular the genetic relationships between members of the M. sativa complex, as deduced by DNA analysis. Also, the differences in breeding behaviour and vigour of diploids versus autotetraploids, and the underlying genetic causes, are discussed in relation to lucerne improvement. Medicago falcata, a member of the M. sativa complex, has contributed substantially to lucerne improvement in North America, and its diverse genetics would appear to have been under-utilised in Australian programs over the last two decades, despite the reduced need for tolerance to freezing injury in Australian environments. Breeding of lucerne in Australia only commenced on a large scale in 1977, driven by an urgent need to introgress aphid resistance into adapted backgrounds. The release in the early 1980s of lucernes with multiple pest and disease resistance (aphids, Phytophthora, Colletotrichum) had a significant effect on increasing lucerne productivity and persistence in eastern Australia, with yield increases under high disease pressure of up to 300% being recorded over the predominant Australian cultivar, up to 1977, Hunter River. Since that period, irrigated lucerne yields have plateaued, highlighting the need to identify breeding objectives, technologies, and the germplasm that will create new opportunities for increasing performance. This review discusses major goals for lucerne improvement programs in Australia, and provides indications of the germplasm sources and technologies that are likely to deliver the desired outcomes.

Young people with intellectual disabilities attending mainstream and segregated schooling: perceived stigma, social comparison and future aspirations

Mainstream schooling is a key policy in the promotion of social inclusion of young people with learning disabilities. Yet there is limited evidence about the school experience of young people about to leave mainstream as compared with segregated education, and how it impacts on their relative view of self and future aspirations. Sixty young people with mild to moderate intellectual disabilities in their final year of secondary school participated in this study. Twenty-eight individuals came from mainstream schools and 32 attended segregated school. They completed a series of self-report measures on perceptions of stigma, social comparison to a more disabled and non-disabled peer and the likelihood involved in attaining their future goals. The majority of participants from both groups reported experiencing stigmatized treatment in the local area where they lived. The mainstream group reported significant additional stigma at school. In terms of social comparisons, both groups compared themselves positively with a more disabled peer and with a non-disabled peer. While the mainstream pupils had more ambitious work-related aspirations, both groups felt it equally likely that they would attain their future goals. Although the participants from segregated schools came from significantly more deprived areas and had lower scores on tests of cognitive functioning, neither of these factors appeared to have an impact on their experience of stigma, social comparisons or future aspirations. Irrespective of schooling environment, the young people appeared to be able to cope with the threats to their identities and retained a sense of optimism about their future. Nevertheless, negative treatment reported by the children was a serious source of concern and there is a need for schools to promote the emotional well-being of pupils with intellectual disabilities.

Metas do Conselho Nacional de Justi??a 2012/2013: uma an??lise dos contornos gerenciais assumidos pela reforma do poder judici??rio no Brasil

Este artigo tem como objetivo avan??ar no estudo do processo de reforma do Poder Judici??rio brasileiro, o qual se insere no processo de reforma do Estado p??trio. A partir das contribui????es de Osborne e Gaebler (1992) e Abrucio (2006), buscou-se tra??ar um paralelo entre as l??gicas gerencial e fiscal e esclarecer como as mesmas refletiram nos indicadores de efic??cia, efici??ncia e efetividade do Poder Judici??rio no Brasil. Para atingir o objetivo proposto, optou-se por utilizar como m??todo a an??lise de conte??do de Bardin (2002), pela regra de enumera????o do tipo frequ??ncia, buscando, com isso, observar o papel que o Conselho Nacional de Justi??a exerceu nesse processo e a l??gica do plano de metas estabelecido pela institui????o para os anos de 2012 e 2013. Como resultado, observou-se que as metas estabelecidas para o bi??nio buscaram implantar uma gest??o mais eficaz nesse n??cleo estrat??gico do Estado, com ??nfase na celeridade processual, gest??o administrativa e informatiza????o dos procedimentos. Percebeu-se que a l??gica gerencial continua exercendo grande influ??ncia no modelo de gest??o adotado. Como novidade, verificou-se a inser????o de indicadores de efetividade, os quais podem permitir aproximar os objetivos dessa esfera de poder com os da sociedade brasileira, repercutindo na elabora????o de metas futuras.

Avaliação do potencial económico de implementação da construção em BTC

Dissertação de mestrado integrado em Engenharia Civil

Ohjelmistotalon toimintaprosessien kehittäminen

Työn tavoitteena oli kehittää MaestroYhtiöiden liiketoimintaprosesseja. Ensin selvitettiin liiketoimintaprosessien nykytila, jonka perusteella kehitettiin, kuvattiin rajapintoineen ja ohjeistettiin uudet liiketoimintaprosessit. Lopuksi määriteltiin muutamia prosessimittareita lähinnä tuotantotiimin käyttöön. Prosessien kehittämisen lisäksi tehtiin toiminnan kehittämissuunnitelma ohjausryhmäksi kutsutun kehittämistiimin toimesta ulkopuolisen konsultin avustamana. Ohjausryhmä määritteli tavoitteita toiminnalle ja konkreettisia keinoja niiden saavuttamiseksi. Tämän jälkeen tehtiin aikataulu tavoitteiden toteuttamiseksi. Tavoitteiden toteutumista seurataan säännöllisesti. Yrityksen kasvaessa on henkilökunnan määrä lisääntynyt nopeasti. Henkilöstömäärän kasvuvauhti on edennyt siinä määrin, että toimintatapoja on kehitettävä ja vakinaistettava, jotta pystytään toimimaan tehokkaasti ja sujuvasti. Taustalla on myös kahden eri toimipisteen erilaiset vaiheet. Savonlinnan toimipisteessä toiminta on jo vakiintunutta, mutta siellä onkin toimittu ohjelmistotuotannon parissa useita vuosia pidempään kuin Lappeenrannassa. Lappeenrannassa puolestaan tuotanto aloitettiin noin puolet pienemmällä miehityksellä kuin mitä se nykyään on ja toiminta hakee vielä muotoaan. Tarvetta toimintojen yhtenäistämiseen ja kehittämiseen eri tiimeissä ja toimipisteissä on, sillä yhteiset toimintatavat parantavat työn laatua ja tehokkuutta. Tuloksena työstä syntyi uudet prosessit kaikille tiimeille. Uudet rajapintoineen kuvatut prosessit on myös ohjeistettuna. Uusitut prosessit ovat seuraavassa vaiheessa saatava käyttöön. Prosessien käyttöönotto on tiiminvetäjien vastuulla. Myös prosessimittareiden käyttö ja seuraaminen on tiiminvetäjien vastuulla. Ohjausryhmän toiminnasta syntyi lista tavoitteita ja aikataulu tavoitteiden saavuttamiseksi. Tämän työn aikana päästiin ensimmäiseen aikataulun mukaiseen etappiin ja tavoitteet olivat toteutuneet melko hyvin. Tämä ohjausryhmän toiminta jatkuu tulevaisuudessakin tavoitteiden seurannan muodossa. Mahdollisesti ohjausryhmä voi myös luoda uusia tavoitteita samalla tavalla ja seurata niiden toteutumista.

Implementação do OEE nas máquinas de laminação a frio

Through a description of the productivity problems experienced by some enterprises, to optimize their respective production lines, results of poor performance or low quality, the following work aims to explain and demonstrate the practical application of the theory of overall equipment effectiveness (OEE) on cold lamination machines in a steel industry . The project, to ensure your goal, is based on structuring a complete planning to increase levels of performance, availability and quality relating to rolling. On completion of the work, will be presented forecasts of future goals for the OEE, to search for continuous improvement and global standards of efficiency, taking into account, the sector the company operates, the history of the laminators, and financial aspects

Implementação do OEE nas máquinas de laminação a frio

Through a description of the productivity problems experienced by some enterprises, to optimize their respective production lines, results of poor performance or low quality, the following work aims to explain and demonstrate the practical application of the theory of overall equipment effectiveness (OEE) on cold lamination machines in a steel industry . The project, to ensure your goal, is based on structuring a complete planning to increase levels of performance, availability and quality relating to rolling. On completion of the work, will be presented forecasts of future goals for the OEE, to search for continuous improvement and global standards of efficiency, taking into account, the sector the company operates, the history of the laminators, and financial aspects

Image Processing Challenges in the Creation of Spatiotemporal Gene Expression Atlases of Developing Embryos

To properly understand and model animal embryogenesis it is crucial to obtain detailed measurements, both in time and space, about their gene expression domains and cell dynamics. Such challenge has been confronted in recent years by a surge of atlases which integrate a statistically relevant number of different individuals to get robust, complete information about their spatiotemporal locations of gene patterns. This paper will discuss the fundamental image analysis strategies required to build such models and the most common problems found along the way. We also discuss the main challenges and future goals in the field.

Image Processing Challenges in the Creation of Spatiotemporal Gene Expression Atlases of Developing Embryos

To properly understand and model animal embryogenesis it is crucial to obtain detailed measurements, both in time and space, about their gene expression domains and cell dynamics. Such challenge has been confronted in recent years by a surge of atlases which integrate a statistically relevant number of different individuals to get robust, complete information about their spatiotemporal locations of gene patterns. This paper will discuss the fundamental image analysis strategies required to build such models and the most common problems found along the way. We also discuss the main challenges and future goals in the field.

Effect of a variable delay in delayed dynamical systems

We report numerical evidence of the effects of a periodic modulation in the delay time of a delayed dynamical system. By referring to a Mackey-Glass equation and by adding a modula- tion in the delay time, we describe how the solution of the system passes from being chaotic to shadow periodic states. We analyze this transition for both sinusoidal and sawtooth wave mod- ulations, and we give, in the latter case, the relationship between the period of the shadowed orbit and the amplitude of the modulation. Future goals and open questions are highlighted.

Relationship Maintenance in Couples with a Partner Who Has Attention Deficit Hyperactivity Disorder

The body of research on the relationship functioning of adults with attention deficit hyperactivity disorder (ADHD) is relatively small; the aim of the present study is to advance our understanding of this topic. It has been estimated that three to ten percent of children and one to five percent of adults have impairing symptoms of ADHD, which is a total of 4 million children and 4-5 million adults in the U.S. (Wender, 2000). A recent prevalence study found that approximately 4.4% of adults in the U.S. meet the criteria for a diagnosis of ADHD (Kessler et al., 2006). Children with ADHD show innate temperamental characteristics, usually inattentiveness, distractibility, impulsivity, restlessness, demandingness, hyperreactivity, low tolerance for frustration, temperoutbursts, bossiness and stubbornness, and mood lability, along with an innate proclivity for academic underachievement. It has been estimated that one- to two-thirds of children with ADHD have symptoms that continue into adulthood, and for 40-50% of these adults, these symptoms are serious enough to cause impairment in functioning (Everett & Everett, 1999; Wender, 2000). Research suggests that the majority of cases are transmitted genetically, but some may be due to exposure to environmental toxins such as lead. Consumption of excess sugar or allergies to food may exacerbate or mimic ADHD symptoms in some children, but they are not a cause of ADHD (Wender, 2000). One hypothesized cause of the symptoms associated with ADHD is a deficit in the brain's executive functioning (Barkley & Gordon, 2002). Executive functioning can be conceptualized as the ability to inhibit, organize, and plan behaviors. Barkley and Gordon (2002) define it as the abilityto self-direct and regulate behaviors toward future goals, including social behaviors and goals. Other research suggests that executive functioning consists of inhibition, control of interference, verbal and nonverbal working memory, emotional regulation, attention, verbal fluency, visual scanning, and processing speed. Studies have shown impairments in these areas among adults with ADHD (Barkley & Gordon, 2002; Barkley, Murphy & Kwasnik, 1996; Goldstein, 2002).

Paediatric research in emergency departments international collaborative (PREDICT): First steps towards the development of an Australian and New Zealand research network

Paediatric emergency research is hampered by a number of barriers that can be overcome by a multicentre approach. In 2004, an Australia and New Zealand-based paediatric emergency research network was formed, the Paediatric Research in Emergency Departments International Collaborative (PREDICT). The founding sites include all major tertiary children’s hospital EDs in Australia and New Zealand and a major mixed ED in Australia. PREDICT aims to provide leadership and infrastructure for multicentre research at the highest standard, facilitate collaboration between institutions, health-care providers and researchers and ultimately improve patient outcome. Initial network-wide projects have been determined. The present article describes the development of the network, its structure and future goals.

G-protein-coupled receptors:from structural insights to functional mechanisms

The papers resulting from the recent Biochemical Society Focused Meeting 'G-Protein-Coupled Receptors: from Structural Insights to Functional Mechanisms' held in Prato in September 2012 are introduced in the present overview. A number of future goals for GPCR (G-protein-coupled receptor) research are considered, including the need to develop biophysical and computational methods to explore the full range of GPCR conformations and their dynamics, the need to develop methods to take this into account for drug discovery and the importance of relating observations on isolated receptors or receptors expressed in model systems to receptor function in vivo. © 2013 Biochemical Society.