Image Processing Challenges in the Creation of Spatiotemporal Gene Expression Atlases of Developing Embryos


Autoria(s): Castro González, Carlos; Luengo Oroz, Miguel Ángel; Douloquin, Louise; Thierry, Savy; Melani, Camilo; Desnoulez, Sophie; Bourgine, Paul; Peyrieras, Nadine; Ledesma Carbayo, María Jesús; Santos Lleo, Andres de
Data(s)

2011

Resumo

To properly understand and model animal embryogenesis it is crucial to obtain detailed measurements, both in time and space, about their gene expression domains and cell dynamics. Such challenge has been confronted in recent years by a surge of atlases which integrate a statistically relevant number of different individuals to get robust, complete information about their spatiotemporal locations of gene patterns. This paper will discuss the fundamental image analysis strategies required to build such models and the most common problems found along the way. We also discuss the main challenges and future goals in the field.

Formato

application/pdf

Identificador

http://oa.upm.es/12046/

Idioma(s)

spa

Publicador

E.T.S.I. Telecomunicación (UPM)

Relação

http://oa.upm.es/12046/1/INVE_MEM_2011_104598.pdf

http://ieeexplore.ieee.org/xpl/articleDetails.jsp?arnumber=6091687

info:eu-repo/semantics/altIdentifier/doi/10.1109/IEMBS.2011.6091687

Direitos

http://creativecommons.org/licenses/by-nc-nd/3.0/es/

info:eu-repo/semantics/openAccess

Fonte

Proceedings of 33rd Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC 2011) | 33rd Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC 2011) | 30/08/2011 - 03/09/2011 | Boston, MA, EEUU

Palavras-Chave #Medicina #Electrónica #Telecomunicaciones
Tipo

info:eu-repo/semantics/conferenceObject

Ponencia en Congreso o Jornada

PeerReviewed