Sinónimos castellanos Roque Barcia

UANL

Guía del lenguaje ó síntesis de la gramática : colección de homónimos, sinónimos, galicismos, refranes y frases

UANL

Sinónimos Castellanos

La Editorial Universidad del Rosario presenta esta nueva edición del clásico diccionario, del filósofo, lexicógrafo y político republicano español Roque Barcia, obra pionera en su época y publicada por primera vez en 1984; el cual permitirá rescatar palabras olvidadas del lenguaje y enriquecer el vocabulario con nuevos vocablos. Esta se constituye en la primera obra de la Colección Clásicos del Saber, cuyo objetivo es publicar obras que han sifo importantes para el patrimonio cultural de los hispanohablantes.Vale la pena recalcar la importancia que ha tomado el español en el mundo: es uno de los 6 idiomas oficiales de la ONU, es el idioma oficial de muchas de las principales organizaciones internacionales político económicas como la OEA, la OEI, la EU, la CAN, UNASUR y Caricom, entre otras y la población hispanohablante conforma uno de los sectores de mayor crecimiento internacional, ya que brinda al mundo una vasta variedad de productos culturales y de servicios, y se constituye en un nicho muy atractivo para el desarrollo de nuevos negocios.

Comprender e interpretar no son sinónimos.

Resumen basado en el de la publicación. Resumen en inglés. Monográfico: Las minificciones en el aula

Análise do efeito de polimorfismos não-sinônimos em genes de reparo de DNA da via BER na resposta inflamatória da meningite

In vitro and in animal models, APE1, OGG1, and PARP-1 have been proposed as being involved with inflammatory response. In this work, we have investigated if the SNPs APE1 Asn148Glu, OGG1 Ser326Cys, and PARP-1 Val762Ala are associated to meningitis and also developed a system to enable the functional analysis of polymorphic proteins. Patients with bacterial meningitis (BM), aseptic meningitis (AM) and controls (non-infected) genotypes were investigated by PIRA-PCR or PCR-RFLP. DNA damages were detected in genomic DNA by Fpg treatment. IgG and IgA were measured from plasma and the cytokines and chemokines were measured from cerebrospinal fluid samples using Bio-Plex assays. The levels of NF-κB and c-Jun were measured in CSF by dot blot assays. A significant (P<0.05) increase in the frequency of APE1 148Glu allele in BM and AM patients was observed. A significant increase in the genotypes Asn/Asn in control group and Asn/Glu in BM group was also found. For the SNP OGG1 Ser326Cys, the genotype Cys/Cys was more frequent (P<0.05) in BM group. The frequency of PARP-1 Val/Val genotype was higher in control group (P<0.05). The occurrence of combined SNPs increased significantly in BM patients, indicating that these SNPs may be associated to the disease. Increasing in sensitive sites to Fpg was observed in carriers of APE1 148Glu allele or OGG1 326Cys allele, suggesting that SNPs affect DNA repair activity. Alterations in IgG production were observed in the presence of SNPs APE1Asn148Glu, OGG1Ser326Cys or PARP-1Val762Ala. Reductions in the levels ofIL-6, IL-1Ra, MCP-1/CCL2and IL-8/CXCL8 were observed in the presence of APE1148Glu allele in BM patients, however no differences were observed in the levels of NF-κB and c-Jun considering genotypes and analyzed groups. Using APE1 as model, a system to enable the analysis of cellular effects and functional characterization of polymorphic proteins was developed using strategies of cloning APE1 cDNA in pIRES2-EGFP vector, cellular transfection of the construction obtained, siRNA for endogenous APE1 and cellular cultures genotyping. In conclusion, we obtained evidences of an effect of SNPs in DNA repair genes on the regulation of immune response. This is a pioneering work in the field that shows association of BER variant enzymes with an infectious disease in human patients, suggesting that the SNPs analyzed may affect immune response and damage by oxidative stress level during brain infection. Considering these data, new approaches of functional characterization must be developed to better analysis and interactions of polymorphic proteins in response to this context

Palavrões ou palavras: um estudo com educadoras/es sobre sinônimos usados na denominação de temas relacionados ao sexo

Pós-graduação em Educação Escolar - FCLAR

Sinónimos castellanos y voces de sentido análogo,

Mode of access: Internet.

Exámen de la posibilidad de fixar la significacion de los sinónimos de la lengua castellana /

Mode of access: Internet.

Colección de sinónimos de la lengua castellana /

Mode of access: Internet.

Examen de la posibilidad de fixar la significacion de los sinónimos de la lengua castellana /

Mode of access: Internet.

Examen de la posibilidad de fixar la significación de los sinónimos de la lengua castellana /

Contiene: t. 1.

Parte práctica de botánica del caballero Cárlos Linneo, que comprehende las clases, órdenes, géneros, especies y variedades de las plantas, con sus caracteres genéricos y específicos, sinónimos mas selectos, nombres triviales, lugares donde nacen y propiedades /

Mode of access: Internet.