49 resultados para SDRA
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1 kartta :, vär. ;, 19,5 x 53,3 cm, lehti 22,5 x 55,5 cm, [N. 1:1030000]
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1 kartta :, vär. ;, 24 x 62,5 cm, lehti 35,5 x 73 cm, [N 1:1190000]
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Kartan esitystekniikka: maastokartta
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Kartan esitystekniikka: maastokartta
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Kartan esitystekniikka: maastokartta
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Kartan esitystekniikka: maastokartta
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Kartan esitystekniikka: maastokartta
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Kartan esitystekniikka: maastokartta
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Kartan esitystekniikka: maastokartta
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Le syndrome de détresse respiratoire aiguë (SDRA) se développe suite à une atteinte pulmonaire lésionnelle, induisant un œdème et une inflammation excessive, généralement suivis d’une réparation atypique menant à la fibrose. Malgré de signifiants progrès dans les traitements, la mortalité reste élevée : ~ 40 %. Mon hypothèse de travail est que l’atténuation de l’œdème ou de la réponse inflammatoire pourrait freiner le développement ou la sévérité de la phase exsudative. Nous avons évalué cette hypothèse à l’aide d’un modèle de phase exsudative du SDRA, i.e. instillation intra-trachéale de bléomycine, chez les souris. La modulation des fluides alvéolaires est étudiée avec des souris transgénique (Tg) pour le canal ENaC, qui sont sensibles à la formation d’un œdème. Cependant, ces souris Tg ne sont pas plus sensibles au développement de la phase exsudative en condition lésionnelle (bléomycine). Nous avons déterminé par une étude électrophysiologique des cellules épithéliales alvéolaires de type II (AT II) que ce n’est pas lié à une inhibition par la bléomycine de la fonction du canal ENaC. Le traitement de la réponse inflammatoire associée au SDRA par des glucocorticoïdes est une thérapie potentielle mais controversée. Les glucocorticoïdes dans notre modèle murin ne réduisent pas la sévérité des lésions. Nous avons pu déterminé lors d’expériences in vitro que ce serait dû à une réduction de la capacité de réparation des AT II. En résumé : La modulation du canal ENaC ne modifie pas le développement de la phase exsudative, suggérant que la régulation de l’œdème n’est pas suffisante pour modifier l’évolution du SDRA. La modulation de l’inflammation par les glucocorticoïdes est ineffective, possiblement à cause d’une altération de la réparation. Mon étude suggère que le traitement de la phase exsudative du SDRA est complexe. En effet, la régulation de l’œdème ou de l’inflammation de façon isolée ne peut pas modifier l’évolution du SDRA. L'hétérogénéité des sources du SDRA et la redondance des mécanismes cellulaires impliqués dans l’évolution des lésions pulmonaires suggèrent que le traitement nécessitera une approche visant plusieurs cibles mécanistiques afin d’en accélérer la résolution.
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Undersökningens huvudsyfte är att se om synen på djur, närmare bestämt hästar, skiljer sig åt hos försäkringstagarna i södra Dalarnas hästförsäkringsförening under åren 1885-1894. Dess-utom att utforska vilka som var upphovsmännen till föreningen, och vilka människor som attraherades av hästförsäkringsföreningens verksamhet. Materialet som skall besvara syftet består av protokoll från hästförsäkringsföreningens regelbundet hållna styrelsemöten, och Kopparbergs läns kalender. Undersökningens resultat visar att det hos bönderna som hästägare går att se att hästen värderades högre än ett arbetsredskap, att bruken och bönderna är dom dominerande försäk-ringstagarna och att det var betydelsefulla herrar som låg bakom starten av försäkringsföre-ningen
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De svenska exportsträvandena kring sekelskiftet 1900 har belysts i några studier. Trots det vet vi lite om hur de svenska varorna mottogs och vilka problem som uppstod när Sverige på allvar gav sig ut på den globala marknaden. Denna artikel syftar till att avhjälpa denna brist genom att lyfta fram svenska exportproblem i relation till marknaderna i Södra Afrika vid sekelskiftet 1900. Det huvudsakliga materialet i artikeln består av 27 rapporter som skrevs av en exportagent och fem handelsstipendiater. Vad berättade de om problemen och hur reagerade man i samtiden på vad de berättade? I rapporterna från Södra Afrika beskrivs en rad utmaningar som den svenska exportsektorn var tvungen att övervinna för att kunna konkurrera på marknaderna. Dessa utmaningar har i artikeln sorterats in i tre olika kategorier. Varje kategori består av ett större problemkomplex som utgår från orsaker respektive lösningar på problemen. De tre kategorierna är de marknadsekonomiska problemen, de organisatoriskaproblemen och de nationella varumärkesrelateradeproblemen. Under perioden 1894-1908 skedde det en viss förskjutning från att bara marknadsekonomiska problem betonas till att de organisatoriska och nationellt varumärkesrelaterade problemen framträder. Denna förskjutning sammanfaller med det ”nationella uppvaknandet” i Sverige och framväxten av en ny nationalism fokuserad på industrialisering och modern teknologi. I artikeln framkommer det även att de problem och lösningar som lyftes fram i rapporterna från Södra Afrika inte var unika på något vis. I tidskriften Svensk Export, som gavs ut av Sveriges Allmänna Exportförening, publicerades det många artiklar och rapporter – både svenska och utländska - i vilka likartade problem och lösningar presenterades. Det handlade till exempel om att rätta sig efter efterfrågan, att skicka kunniga personer som kunde undersöka marknaderna, att göra reklam, att trycka kataloger på försäljningsmarknadens språk, att förbättra exportorganisationen och att industriidkare borde slå sig samman och arbeta tillsammans i form av handelsbolag.
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Idyll or Reality? Albert Edelfelt, Gunnar Berndtson and the ambivalent breakthrough of modernity Albert Edelfelt (1854-1905) and Gunnar Berndtson (1854-1895) have much in common. In this dissertation, I study their paintings of local peasants and fishermen and of the gentry’s summer in the county of Uusimaa in southern Finland, in the context of Nordic history of ideas. The breakthrough of modernity, with its attention on debating social problems, provides a novel angle into the oeuvres of the two artists. My focus is on the paintings which emerge in the collision of the public discussion of social matters and the values of the artists’ manorial milieu. The artists’ relation to the public discussion is scrutinized through two of the main topics: the question of the common people and democracy, and the question of equality between men and women. My dissertation is a contextual study which is based on the analysis of the artworks of Edelfelt and Berndtson, on their letters, and on the study of drama and fiction of their time. The notion “liberté, egalité, fraternité” is linked to the breakthrough of modernity. Both artists were aware of the ideal of equality. They used the means and the themes of contemporary art in their presentations, but their pictures contain the ideal of an earlier epoch: the hardworking, but still complacent common people. This conception of the common people is also reflected in the poems of J. L. Runeberg. Women of the late 19th century challenged woman’s primary role as wife and mother. In Edelfelt’s and Berndtson’s depictions of the gentry enjoying summer, women and children have the main role. Notwithstanding the debate of the breakthrough of modernity they depicted women almost without exception as good mothers. Their paintings often depict lazy days in the sunshine, which were, in reality, rare moments for the mistress of the house. Edelfelt’s and Berndtson’s subjects from the Uusimaa countryside coincide with the topics of the breakthrough of modernity, but both the pictures of the common people and the depictions of the gentry enjoying summer, are a retouched picture of reality, often an idyll, in which the public discussion of social matters is evident only materially or not at all.
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With respect to resource management and environmental impact, organic farming offers rationales for agricultural sustainability. However, agronomic productivity is usually higher with conventional farming. This work aimed at investigating two factors of major importance for the agronomic productivity of organic crop husbandry, nitrogen (N) supply through symbiotic N fixation (SNF) and weed occurrence. Perennial red clover-grass leys and spring cereal crops subjected to regular agricultural practices were studied on 34 organic farms located in the southern and the north-western coastal regions of Finland. Herbage growth, clover content as a proportion of the ley and extent of SNF in perennial leys, and the occurrence of weed species and weed-crop competition in spring cereal stands were related to climate conditions, soil properties, and management measures. The herbage accumulated from the first and the second cut of one- and two-year-old leys averaged 7.5 t DM ha-1 (SD ± 1.7 t DM ha-1); the clover content averaged 43.9% (SD ± 18.8%). Along with the clover content, herbage production decreased with ley age. Radiation use efficiency (RUE) correlated positively with clover proportion but despite low clover contents, three-year-old leys were still productive with regard to RUE. SNF in the accumulated annual growth of one- and two-year-old leys averaged 247.5 kg N ha-1 yr-1 (SD ± 114.4 kg N ha-1 yr-1). It was supposed that if red clover-grass leys constituted 40% of the rotation, then the mean N supply by SNF would be able to sustain two or three succeeding cereal crops (green manure and forage ley, respectively), yielding 3.0 to 4.0 t grain ha-1. Being a function of clover biomass, the SNF increased from the first to the second cut and thereafter declined with ley age. Coefficients of variation of clover contents (and SNF) between and within fields were around 50%, which was about twice as high as those of herbage production. The lower were the clover contents, the higher were the within-field variations of clover as a proportion of the ley. Low clover contents in one-year-old leys and increasing variability with ley age suggested that red clover growth was limited by poor establishment and poor overwintering. The proportions of clover in leys were lower and their variability was higher in the northwest than in the south. Soil properties, primarily texture and structure, had a major impact on clover proportion and herbage production, which largely explained regional differences in ley growth. Within-field variability of soil properties can be amended through site-specific measures, including drainage, liming, and applications of organic manures and mineral fertilizers. Overwintering and the persistence of leys can be improved by the choice of winter-hardy varieties, careful establishment and the appropriate harvest regime. Mean grain yields of spring cereal crops amounted to 3.2 t ha-1 in the south and 3.6 t ha-1 in the northwest. At 570 and 565 m-2 for the south and northwest respectively, mean weed densities did not differ between the regions, whereas the respective mean weed biomass of 697 and 1594 kg dry weight ha-1, respectively did differ. Weed abundance varied remarkably between single fields. The number of weed species was higher in the south than in the northwest. For example, Fumaria officinalis and Lamium spp. were found only in the south. Frequencies and abundances of Lapsana communis, Myosotis arvensis, Polygonum aviculare, Tripleurospermum inodorum, and Vicia spp. were higher in the south, whereas those of Elymus repens, Persicaria spp. and Spergula arvensis were higher in the northwest. The number of years since conversion to organic farming, i.e. long-term management, was one of the variables that explained the abundance of single weed species. E. repens was the weed species whose biomass increased most with the duration of organic farming. Another significant variable was crop biomass, which was affected by short-term management. The presence of different weed species was related to the duration of organic farming and to low crop yield. This finding demonstrated that it was not the organic farming regime per se, which resulted in high weed infestation and low yielding crops, but failures in the understanding and the management of organic farming systems. Successful weed control relies on farm- and field-specific long- and short-term management approaches. The agronomic productivity of ley and spring cereal crops managed by full-time farmers with an interest in organic farming was on the same level as of the mean for conventional farming. Given the many options for further improvements of the agronomic performance of organic arable systems, organic farming offers foundations for the development of sustainable agriculture. The main threat to the sustainability of farming in Finland, both conventional and organic, is the spatial separation of crop production and animal husbandry by region, along with the simplification of associated crop rotations.