Articular Cartilage in the Knee: Current MR Imaging Techniques and Applications in Clinical Practice and Research

Magnetic resonance (MR) imaging is the most important imaging modality for the evaluation of traumatic or degenerative cartilaginous lesions in the knee. It is a powerful noninvasive tool for detecting such lesions and monitoring the effects of pharmacologic and surgical therapy. The specific MR imaging techniques used for these purposes can be divided into two broad categories according to their usefulness for morphologic or compositional evaluation. To assess the structure of knee cartilage, standard spin-echo (SE) and gradient-recalled echo (GRE) sequences, fast SE sequences, and three-dimensional SE and GRE sequences are available. These techniques allow the detection of morphologic defects in the articular cartilage of the knee and are commonly used in research for semiquantitative and quantitative assessments of cartilage. To evaluate the collagen network and proteoglycan content in the knee cartilage matrix, compositional assessment techniques such as T2 mapping, delayed gadolinium-enhanced MR imaging of cartilage (or dGEMRIC), T1 rho imaging, sodium imaging, and diffusion-weighted imaging are available. These techniques may be used in various combinations and at various magnetic field strengths in clinical and research settings to improve the characterization of changes in cartilage. (C)RSNA, 2011 , radiographics.rsna.org

Development of pharmaceutical care services in nursing homes: practice and research in a Swiss canton.

OBJECTIVE: The aim of this study was to assess the implementation process and economic impact of a new pharmaceutical care service provided since 2002 by pharmacists in Swiss nursing homes. SETTING: The setting was 42 nursing homes located in the canton of Fribourg, Switzerland under the responsibility of 22 pharmacists. METHOD: We developed different facilitators, such as a monitoring system, a coaching program, and a research project, to help pharmacists change their practice and to improve implementation of this new service. We evaluated the implementation rate of the service delivered in nursing homes. We assessed the economic impact of the service since its start in 2002 using statistical evaluation (Chow test) with retrospective analysis of the annual drug costs per resident over an 8-year period (1998-2005). MAIN OUTCOME MEASURES: The description of the facilitators and their implications in implementation of the service; the economic impact of the service since its start in 2002. RESULTS: In 2005, after a 4-year implementation period supported by the introduction of facilitators of practice change, all 42 nursing homes (2,214 residents) had implemented the pharmaceutical care service. The annual drug costs per resident decreased by about 16.4% between 2002 and 2005; this change proved to be highly significant. The performance of the pharmacists continuously improved using a specific coaching program including an annual expert comparative report, working groups, interdisciplinary continuing education symposia, and individual feedback. This research project also determined priorities to develop practice guidelines to prevent drug-related problems in nursing homes, especially in relation to the use of psychotropic drugs. CONCLUSION: The pharmaceutical care service was fully and successfully implemented in Fribourg's nursing homes within a period of 4 years. These findings highlight the importance of facilitators designed to assist pharmacists in the implementation of practice changes. The economic impact was confirmed on a large scale, and priorities for clinical and pharmacoeconomic research were identified in order to continue to improve the quality of integrated care for the elderly.

Establishment of a Representative Practice-based Research Network (PBRN) for the Monitoring of Primary Care in Switzerland.

Data are urgently needed to better understand processes of care in Swiss primary care (PC). A total of 2027 PC physicians, stratified by canton, were invited to participate in the Swiss Primary care Active Monitoring network, of whom 200 accepted to join. There were no significant differences between participants and a random sample drawn from the same physician databases based on sex, year of obtaining medical school diploma, or location. The Swiss Primary care Active Monitoring network represents the first large-scale, nationally representative practice-based research network in Switzerland and will provide a unique opportunity to better understand the functioning of Swiss PC.

Adult literacy, numeracy and language : policy, practice and research.

Es un recurso para los profesionales, investigadores y estudiantes de los cursos de adultos y educación continua, para estudiantes de postgrado e investigadores en el campo de la educación post-obligatoria. Estudia la práctica social de la alfabetización, la aritmética y el lenguaje y las implicaciones de la enseñanza y el aprendizaje de las competencias básicas de los adultos. Los principales expertos internacionales propugnan un cambio en el enfoque de su definición por otra más abierta que sostiene que la alfabetización, la aritmética y el lenguaje son más que un conjunto de habilidades o técnicas, pues están determinadas por el contexto social y cultural en el que están teniendo lugar, el sentido que tienen para los usuarios, y los fines que persiguen.

Practice Literate Research: Turning the Tables

Researchers complain how difficult it is to get practitioners and policymakers to use research. In contrast, this paper looks at the issues from the perspective of practice, and argues that it is the researcher’s job to become more practice-literate, so that research begins with practice concerns and develops practice-based solutions. The paper explores the relationship between research and practice and suggests that research has insufficiently engaged with the nature of practice and practice knowledge. Using the Salisbury Statement on practice research (Salisbury Statement 2010) the paper offers a definition of practice research and analyses what would be required for an agenda for practice research. Finally the paper proposes five functions for practice research.

Plenary papers of the 1999 Conference on Criminal Justice Research and Evaluation--enhancing policy and practice through research.

"Sept. 2000" (v. 3).

Mental health consultation theory, practice, and research 1973-1978 : an annotated reference guide /

Mode of access: Internet.

Portugal- First Steps of Postvention Practice and Research

This chapter discusses the state of art of postvention in Portugal, organized into three sections: postvention at school, families bereaved by suicide, and impact of a patient suicide. The first section describes postvention activities in schools when a student dies by suicide. The second part summarizes the studies concerning families bereaved through suicide and implications for practice. The third section presents the research findings about the impact of a patient suicide on health professionals, and the help resources used by these professionals. Despite the major evolutions of the past decade, there remains a clear need to further implement postvention initiatives.