Estudo fitoquímico de goiaba (Psidium guajava L.) com potencial antioxidante para o desenvolvimento de formulação fitocosmética

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Tomate salada: uma alternativa como fonte de antioxidante para uso tópico

Tomato Salad: An Alternative as Antioxidant Source for Topic Use. Tomato is the principal source of lycopene, a carotenoid with high antioxidant activity which can be used topically as a phytocosmetic to combat skin aging. The aim of this study was to get a lycopene-rich extract from salad tomato pulp. The extract was analyzed using UV/vis spectroscopy, thin layer chromatography and high performance liquid chromatography. Oxidant activity was analyzed using the free radical DPPH method. The presence of lycopene in the salad tomato was confirmed. It was present in the apolar fraction rich in carotenoids, which was 96.70% lycopene. In the evaluation of the antioxidant activity, using the radical DPPH, the extract showed activity (IC(50) = 0,311 mg/mL). We conclude that the salad tomato can be used as a source of antioxidants for topic use.

Protocolo para ensaios físico-químicos de estabilidade de fitocosméticos

The growing demand for stable, safe and effective cosmetics has required increasingly complex studies by the scientific community and the use of more efficient techniques to determine the stability of these products. The use of active principles from the Brazilian flora has led to the development of numerous products, in the most varied pharmaceutical forms, making it, even more difficult to standardize experimental protocols to certify the stability of cosmetic preparations. While in Brazil there is no one protocol that standardizes the tests that should be carried out to determine product stability, several studies have been conducted in academic laboratories to determine the stability of specific raw materials. The rheological properties of topical use products have to be taken into account in their manufacture, storage and application. The determination of the rheological behavior of a formulation helps in evaluating the physicochemical nature of the vehicle, allowing early signs of physical instability to be detected and thus enabling quality control of the constituents, test formulations and final products. Thermal analysis has also been used to assist in the study of cosmetic stability and differential scanning calorimetry to guide the development of new products. Other tools, such as fluorimetry and laser granulometry can be used to help the study and development of both emulsified and non-emulsified systems. The aim of the present study is to develop a protocol for the investigation of the physical and chemical stability of phytocosmetics - systems containing active compounds extracted from the Brazilian biodiversity.

Desenvolvimento, avaliação da eficácia e segurança de fitocosmético contendo extrato de Psidium guajava L

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Desenvolvimento e atividade do fitocosmético contendo licopeno para o combate à aceleração do envelhecimento cutâneo

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Avaliação da eficácia e segurança de um sistema emulsionado contendo extrato de Ascophyllum nodosum

Pós-graduação em Ciências Farmacêuticas - FCFAR

Estudo farmacognóstico e desenvolvimento de fitocosmético de ação antioxidante dos frutos de Dimorphandra mollis Benth. (Leguminosae-Caesalpinioideae)

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Caracterização de extratos de cajá-manga (Spondias dulcis Parkinson) potencialmente ativos e seguros para obtenção de fitocosmético antioxidante

Pós-graduação em Ciências Farmacêuticas - FCFAR

Modelos in vitro e in vivo aplicados à avaliação de toxicidade e eficácia de fitocosmético: Serjania marginata Casar. (Sapindaceae)

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Avaliação do perfil químico de fenólicos, do potencial antioxidante e fotoprotetor da torta de semente de Coffea arabica L. (Rubiaceae)

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)