Marilyn Minter in dialague with post-pornography

This paper analyzes post-pornographic practices – an activist and theoretical movement that recognizes pornography as valuable in understanding social, cultural, and political systems that construct and reflect identity – through the work of American artist Marilyn Minter. The analysis contextualizes post-pornography and concludes with an examination of several of Minter’s recent paintings and photographs through a postpornographic lens to assert that these examples of her work explore sexuality and gender by incorporating aesthetic and ideological references to porn and by invoking the postpornographic tenets of collaboration, disruption of public space, and the inversion of heteronormativity. Creating art with Wangechi Mutu, displaying in Times Square high definition videos of lips that slurp green goo, and painting men garbed in lingerie constitute some of Minter’s endeavors, which reenvision pornographic relationships to authorship and agency, public versus private space, and the expression or repression of fantasy.

RRI-GBT MULTI-BAND RECEIVER: MOTIVATION, DESIGN, AND DEVELOPMENT

We report the design and development of a self-contained multi-band receiver (MBR) system, intended for use with a single large aperture to facilitate sensitive and high time-resolution observations simultaneously in 10 discrete frequency bands sampling a wide spectral span (100-1500 MHz) in a nearly log-periodic fashion. The development of this system was primarily motivated by need for tomographic studies of pulsar polar emission regions. Although the system design is optimized for the primary goal, it is also suited for several other interesting astronomical investigations. The system consists of a dual-polarization multi-band feed (with discrete responses corresponding to the 10 bands pre-selected as relatively radio frequency interference free), a common wide-band radio frequency front-end, and independent back-end receiver chains for the 10 individual sub-bands. The raw voltage time sequences corresponding to 16 MHz bandwidth each for the two linear polarization channels and the 10 bands are recorded at the Nyquist rate simultaneously. We present the preliminary results from the tests and pulsar observations carried out with the Robert C. Byrd Green Bank Telescope using this receiver. The system performance implied by these results and possible improvements are also briefly discussed.

Abstract 1905: Defining a therapeutic classification of breast cancer by actionable targets

Breast cancer remains a frequent cause of female cancer death despite the great strides in elucidation of biological subtypes and their reported clinical and prognostic significance. We have defined a general cohort of breast cancers in terms of putative actionable targets, involving growth and proliferative factors, the cell cycle, and apoptotic pathways, both as single biomarkers across a general cohort and within intrinsic molecular subtypes.

We identified 293 patients treated with adjuvant chemotherapy. Additional hormonal therapy and trastuzumab was administered depending on hormonal and HER2 status respectively. We performed immunohistochemistry for ER, PR, HER2, MM1, CK5/6, p53, TOP2A, EGFR, IGF1R, PTEN, p-mTOR and e-cadherin. The cohort was classified into luminal (62%) and non-luminal (38%) tumors as well as luminal A (27%), luminal B HER2 negative (22%) and positive (12%), HER2 enriched (14%) and triple negative (25%). Patients with luminal tumors and co-overexpression of TOP2A or IGF1R loss displayed worse overall survival (p=0.0251 and p=0.0008 respectively). Non-luminal tumors had much greater heterogeneous expression profiles with no individual markers of prognostic significance. Non-luminal tumors were characterised by EGFR and TOP2A overexpression, IGF1R, PTEN and p-mTOR negativity and extreme p53 expression.

Our results indicate that only a minority of intrinsic subtype tumors purely express single novel actionable targets. This lack of pure biomarker expression is particular prevalent in the triple negative subgroup and may allude to the mechanism of targeted therapy inaction and myriad disappointing trial results. Utilising a combinatorial biomarker approach may enhance studies of targeted therapies providing additional information during design and patient selection while also helping decipher negative trial results.

Identificación de errores cometidos en el proceso de despliegue de la política: caso Megaexpress S.A.S y Merca express LTDA.

La presente investigación evalúo errores gerenciales en Megaexpress S.A.S. y Merca Express Ltda., empresas catalogadas en el grupo de micro, pequeñas y medianas empresas (mipymes) en Bogotá, Colombia; pertenecientes al sector de consumo masivo, la primera en venta al detalle o retail y la segunda en distribución a mayoristas. La investigación partió del interés de los investigadores por conocer sobre la relación entre la academia y el sector real y en cómo la academia ayuda a los gerentes a mejorar sus prácticas en la toma de decisiones al momento de enfrentar la realidad empresarial. El estudio de errores gerenciales inicio en el análisis de teoría administrativa sobre el tema abordado por los diferentes autores que conforman el marco referencial en cuanto a cuáles eran los errores en los que incurrían los gerentes y su solución o mejora. Los investigadores utilizaron la herramienta, matriz de convergencias y divergencias, para dicho análisis y de la que se desprende la encuesta, instrumento de investigación, aplicada a gerentes y jefes con personal a cargo de Megaexpress S.A.S. y Mercaexpress Ltda., con el fin de corroborar en que errores incurrían las empresas y llegar a dar recomendaciones para mejorar sus procesos en la toma de decisiones y así contribuir a la perdurabilidad de las empresas.

Evolución de la oruga o constreñimiento de la mariposa: una mirada al rol económico de China en Sudán. (1999- 2008)

La presente monografía tiene como propósito analizar el rol económico de China en Sudán de 1999 al 2008. Tras su crisis en la década de 1990, se examina el efecto que el rol chino tuvo en los sectores productivos de la economía sudanesa: el textil, el agrícola, el metalúrgico y el petrolero, aun cómo la estabilidad política en el régimen de Omar Al-Bashir en el ámbito político y el conflicto en Darfur como factor social. Como un último objetivo esta investigación, basándose en el trabajo de Mohammed Ayoob, se reevalúa el estatus de Sudán como Estado Tercermundista ilustrándolo a través del uso de la analogía de la metamorfosis de una mariposa.

Consumer notes clinical indicators : determining inter-rater reliability with multiple users, nominal categories and several cases

A method of determining inter-rater reliability when there are multiple raters, nominal rating categories and several cases is described and applied in the development of an instrument for auditing the ANZCMHN (1995) standards of practice for mental health nursing in New Zealand. Clinical statements (n=41) from the O’Brien et al (2002a, 2003) study, which reflected nursing behaviours contributing to the achievement of the standards of practice, were used to audit consumer files. During two Phases, the clinical indicator statements were refined and rules for judging the achievement of each statement from case note documentation were established. The resultant statements have adequate inter-rater reliability for the assessment of nursing practice with respect to the ANZCMHN (1995) standards of practice.

Identification of functional domains and evolution of Tc1-like transposable elements.

Tc1-like transposable elements from teleost fish have been phylogenetically examined to determine the mechanisms involved in their evolution and conserved domains of function. We identified two new functional domains in these elements. The first is a bipartite nuclear localization signal, indicating that transposons can take advantage of the transport machinery of host cells for nuclear uptake of their transposases. The second is a novel combination of a paired domain-related protein motif juxtaposed to a leucine zipper-like domain located in the putative DNA-binding regions of the transposases. This domain coexists with a special inverted repeat structure in certain transposons in such phylogenetically distant hosts as fish and insects. Our data indicate that reassortment of functional domains and horizontal transmission between species are involved in the formation and spread of new types of transposable elements.

A strongly magnetized pulsar within the grasp of the milky way’s supermassive black hole

The center of our Galaxy hosts a supermassive black hole, Sagittarius (Sgr) A∗. Young, massive stars within 0.5 pc of Sgr A∗ are evidence of an episode of intense star formation near the black hole a few million years ago, which might have left behind a young neutron star traveling deep into Sgr A∗’s gravitational potential. On 2013 April 25, a short X-ray burst was observed from the direction of the Galactic center. With a series of observations with the Chandra and the Swift satellites, we pinpoint the associated magnetar at an angular distance of 2.4±0.3 arcsec from Sgr A∗, and refine the source spin period and its derivative (P = 3.7635537(2) s and ˙ P = 6.61(4) × 10−12 s s−1), confirmed by quasi simultaneous radio observations performed with the Green Bank Telescope and Parkes Radio Telescope, which also constrain a dispersion measure of DM = 1750 ± 50 pc cm−3, the highest ever observed for a radio pulsar. We have found that this X-ray source is a young magnetar at ≈0.07–2 pc from Sgr A∗. Simulations of its possible motion around Sgr A∗ show that it is likely (∼90% probability) in a bound orbit around the black hole. The radiation front produced by the past activity from the magnetar passing through the molecular clouds surrounding the Galactic center region might be responsible for a large fraction of the light echoes observed in the Fe fluorescence features.

Grundsätze der Volkswirthschaftspolitik : mit anhaltender Rücksicht auf bestehende staatseinrichtungen /

Mode of access: Internet.

Remarks on the practicability of Mr. Robert Owen's plan to improve the condition of the lower classes ...

Dedication signed "Philanthropos".

O PROCESSO DE FORMAÇÃO DA REDE URBANA BAIANA: O MUNICÍPIO DE CANAVIEIRAS- BA NA REDE URBANA REGIONAL

A intensificação do processo de urbanização no Brasil a partir do século XIX condicionou mudanças cruciais na sociedade caracterizando novos padrões de produção, de distribuição e de consumo. A rede urbana, nesse contexto, passou a ser o meio através do qual a produção, a circulação e o consumo se realizam efetivamente, articulando distantes lugares e estabelecendo uma economia e um território nacional. Dessa forma, é de fundamental importância entender a rede urbana como um arcabouço que reforça e influi nos conteúdos sócio-econômicos do território, sendo, portanto, uma dimensão sócio-espacial da sociedade. Pensar a cidade, e de modo especial as pequenas cidades e seu papel na rede urbana nacional e regional permite-nos considerar as especificidades apresentadas pelas mesmas na formação e desenvolvimento urbano do país. O presente trabalho está sendo desenvolvido como parte da revisão bibliográfica do curso de Mestrado em Geografia, no Programa de Pós-Graduação MINTER entre a Universidade Estadual de Campinas (UNICAMP) – Instituto de Geociências e a Universidade Estadual de Santa Cruz (UESC). Essa etapa da pesquisa consiste num estudo de caráter bibliográfico, através do qual objetiva-se analisar o processo de formação da rede urbana no sul da Bahia buscando compreender o papel dos centros de pequeno porte, como a cidade de Canavieiras, no contexto da referida rede. O estudo será norteado pela concepção proposta por Milton Santos (2004) ao considerar que a rede urbana funciona a partir dos dois circuitos da economia urbana e por Roberto Lobato Corrêa (2001) ao afirmar que uma das características marcantes da estrutura dos sistemas de cidades é a organização hierarquizada dos centros urbanos, que variam conforme o tamanho, a qualidade funcional e a extensão da zona de influência espacial dessas aglomerações.