The Spirit of Proclamation

sermon text; MS Word document

Kurtzer Bericht von dem Cometen und dessen Lauff : Welcher gestalt derselbe den 4, 14. Decembris des vorigen 1664. Jahrs in Rom gesehen, und daselbst von gemeltem Dato an, biß auf den 20, 20 desselben Monats observiret werden können ; Gegeben zu Rom 3. Jan. 1665

Athanasius Kircherus

Correlation of TACC3, FGFR3, MMSET and p21 expression with the t(4;14)(p16.3;q32) in multiple myeloma

The t(4;14)(p16;q32) translocation seen in c. 18% of newly diagnosed multiple myeloma (MM) cases, results in FGFR3 activation and creation of an IGH/MMSET fusion transcript. We have recently shown that FGFR3 is activated in only 75% of t(4;14)(+) cases, suggesting that alternative genes near the breakpoint may be involved in the transforming event. The gene, TACC3, located just 50 kb telomeric of FGFR3, with transforming capacity, therefore represented a candidate gene. Using a real-time quantitative polymerase chain reaction-based approach on a cohort of 54 patients, we found a statistically significant, twofold increase in TACC3 expression in t(4;14)(+) cases. TACC3, MMSET and p21 values were positively correlated in all cases and, of particular interest, six patient samples [three t(4;14)(-), three t(4;14)(+)] samples showed a joint up-regulation of TACC3, MMSET and p21. Although a poor prognosis is linked with elevated MMSET expression, an extended follow-up period will be required to evaluate the significance of elevated TACC3 and p21 expression in this subgroup of MM.

Efeito de doses de adubo 4-14-8 na competição entre tomateiro e Solanum americanum em convivência intra e interespecífica

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Translocation (4;14) and concomitant inv(14) in a basal cell carcinoma

Chromosome analysis of short-term cultures from a basal cell carcinoma was performed. The analyzed karyotypes showed a pseudodiploid clone characterized by a der(4)t(4;14)(p14;p11) and a concomitant inversion of the same chromosome 4 involved in the t(4;14) with the breakpoints at p14 and q25.

Mary Elizabeth Frayser Papers - Accession 17 - M4 (4-14)

The Mary Elizabeth Frayser Papers consist of correspondence, related records, and newspaper and magazine clippings. Most of the correspondence is between Estellene Walker and Mary Frayser concerning the work of the State Library Board and the movement for better libraries in South Carolina.

Deß Cometen Lauff Anno 1680 von 4, 14 Novemb. biß zum 24 Novemb., 4 Decemb.

Zu Coburg observirt von Gottfried Kirch