998 resultados para Jackson, Helen Hunt, 1830-1885.


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Gilt illustration on title of cat with pen and ink inditing "Your Aff[ectionate] Pussy".

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"The old black cat" (with music): p. [86]-87.

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"New and enlarged editon" verso of t.p. of: Verses.

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Cover title: Helen Jackson's poems.

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Padget, M. (2004). Indian Country: Travels in the American Southwest. Albuquerque: University of New Mexico Press. RAE2008

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The volumes after the first are numbered consecutively, but bear no collective title. The last volume (xv: Cuba [v.3]) was published after the editor's death. cf. addition to prefatory note in vol. xv, signed: Angelina Miranda de Quesada.

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Degradation of specific protein substrates by the anaphase-promoting complex/cyclosome (APC) is critical for mitotic exit. We have identified the protein Xenopus nuclear factor 7 (Xnf7) as a novel APC inhibitor able to regulate the timing of exit from mitosis. Immunodepletion of Xnf7 from Xenopus laevis egg extracts accelerated the degradation of APC substrates cyclin B1, cyclin B2, and securin upon release from cytostatic factor arrest, whereas excess Xnf7 inhibited APC activity. Interestingly, Xnf7 exhibited intrinsic ubiquitin ligase activity, and this activity was required for APC inhibition. Unlike other reported APC inhibitors, Xnf7 did not associate with Cdc20, but rather bound directly to core subunits of the APC. Furthermore, Xnf7 was required for spindle assembly checkpoint function in egg extracts. These data suggest that Xnf7 is an APC inhibitor able to link spindle status to the APC through direct association with APC core components.