Dinámicas fronterizas, una aproximación desde las políticas del gobierno colombiano para la frontera norte de Santander-Táchira (2010-2014)

El interés de este estudio de caso, es analizar la situación fronteriza en materia comercial y de seguridad; evaluando las políticas públicas implementadas por el gobierno Santos, para darle solución a los problemas estructurales de la zona de estudio, comprendida por Norte de Santander y el Táchira. Adicionalmente se explican los problemas comerciales y de ilegalidad en la zona, que en la actualidad tienden a expandirse como una red controlada por las Farc, Auc y Bandas Criminales, que han cooptado la institucionalidad de ambos Estados. Y finalmente se determina que las políticas implementadas desde la administración Santos han sido insuficientes para terminar los problemas estructurales en materia comercial y de seguridad en la zona.

Caracterización del comportamiento emprendedor de los estudiantes de jurisprudencia de la Universidad del Rosario

Hoy en día, el emprendimiento se ha convertido en uno de los factores esenciales para promover el desarrollo y fomentar la evolución de la sociedad a nivel mundial. Enfocándonos en Colombia y más específicamente en una población delimitada, el centro de emprendimiento de la Universidad del Rosario desarrolló un estudio que permitiera medir la caracterización del perfil emprendedor de sus estudiantes, éste con el objetivo de identificar diferentes variables que inciden en el entorno de los estudiantes al momento de edificar su perfil emprendedor. Por lo anterior, esta investigación se centró en realizar un análisis de la caracterización del comportamiento del perfil emprendedor de los estudiantes de Pregrado de la Facultad de Jurisprudencia de la Universidad del Rosario, la cual permitió comprender un perfil mucho más detallado a la luz de variables identificables. Para su desarrollo, se utilizó la herramienta homologada a nivel internacional conocida como "Características del Comportamiento Emprendedor" o CCE de EMPRETEC basándose en la teoría de McClelland donde se observaron los factores motivacionales que se asocian directamente al comportamiento emprendedor. La metodología usada permitió caracterizar el comportamiento de los estudiantes de la facultad de Jurisprudencia de 1° a 10° semestre mediante la evaluación de 10 factores asociados a necesidades de logro, poder y afiliación.

Biocidas naturais e seus reflexos sobre contaminantes na produção de etanol

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Influence of N-acetylcysteine on oxidative stress in slow-twitch soleus muscle of heart failure rats

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Turismo y trabajo : Una aproximación desde el mercado hotelero

El presente trabajo tiene por objetivo profundizar en el comportamiento del mercado de trabajo en regiones donde la principal actividad económica es el turismo mediante el análisis de la información que desde el año 2004 se obtiene a través de la Encuesta de Ocupación Hotelera (EOH) que releva el INDEC. La posibilidad de contar con la EOH, especialmente en aquellas localidades que, por su dimensión no poseen información proveniente de las Encuestas Permanente de Hogares (EPH), abre la posibilidad de que, a través del comportamiento hotelero y para-hotelero, se acceda a una aproximación de la situación ocupacional en esas localidades, donde se presentan serias dificultades durante algunos períodos del año. Aunque la serie de que se dispone es aún breve 'en el mejor de los casos de hasta cinco años', se la analiza mediante técnicas estadísticas para determinación de estacionalidad, como punto de partida para un posterior seguimiento y puesta en discusión de otras alternativas de abordaje. Se trabaja con localidades de manera desagregada, pudiendo advertirse nítidamente las especificidades según la modalidad turística de cada una de ellas y concentrando el comportamiento de las mismas en dos grupos diferentes: a) Localidades con economías de perfiles más diversificadas; b) Localidades con base económica preponderantemente turística. Mediante este análisis se pretende alcanzar algunos resultados que, eventualmente complementados con información de carácter primaria tanto cuantitativa como de carácter más cualitativo, aporten al conocimiento de un mercado de trabajo cuyas especificidades lo tornan complejo y cuyas consecuencias preocupan tanto al sector público como al privado

Turismo y trabajo : Una aproximación desde el mercado hotelero

El presente trabajo tiene por objetivo profundizar en el comportamiento del mercado de trabajo en regiones donde la principal actividad económica es el turismo mediante el análisis de la información que desde el año 2004 se obtiene a través de la Encuesta de Ocupación Hotelera (EOH) que releva el INDEC. La posibilidad de contar con la EOH, especialmente en aquellas localidades que, por su dimensión no poseen información proveniente de las Encuestas Permanente de Hogares (EPH), abre la posibilidad de que, a través del comportamiento hotelero y para-hotelero, se acceda a una aproximación de la situación ocupacional en esas localidades, donde se presentan serias dificultades durante algunos períodos del año. Aunque la serie de que se dispone es aún breve 'en el mejor de los casos de hasta cinco años', se la analiza mediante técnicas estadísticas para determinación de estacionalidad, como punto de partida para un posterior seguimiento y puesta en discusión de otras alternativas de abordaje. Se trabaja con localidades de manera desagregada, pudiendo advertirse nítidamente las especificidades según la modalidad turística de cada una de ellas y concentrando el comportamiento de las mismas en dos grupos diferentes: a) Localidades con economías de perfiles más diversificadas; b) Localidades con base económica preponderantemente turística. Mediante este análisis se pretende alcanzar algunos resultados que, eventualmente complementados con información de carácter primaria tanto cuantitativa como de carácter más cualitativo, aporten al conocimiento de un mercado de trabajo cuyas especificidades lo tornan complejo y cuyas consecuencias preocupan tanto al sector público como al privado

Turismo y trabajo : Una aproximación desde el mercado hotelero

El presente trabajo tiene por objetivo profundizar en el comportamiento del mercado de trabajo en regiones donde la principal actividad económica es el turismo mediante el análisis de la información que desde el año 2004 se obtiene a través de la Encuesta de Ocupación Hotelera (EOH) que releva el INDEC. La posibilidad de contar con la EOH, especialmente en aquellas localidades que, por su dimensión no poseen información proveniente de las Encuestas Permanente de Hogares (EPH), abre la posibilidad de que, a través del comportamiento hotelero y para-hotelero, se acceda a una aproximación de la situación ocupacional en esas localidades, donde se presentan serias dificultades durante algunos períodos del año. Aunque la serie de que se dispone es aún breve 'en el mejor de los casos de hasta cinco años', se la analiza mediante técnicas estadísticas para determinación de estacionalidad, como punto de partida para un posterior seguimiento y puesta en discusión de otras alternativas de abordaje. Se trabaja con localidades de manera desagregada, pudiendo advertirse nítidamente las especificidades según la modalidad turística de cada una de ellas y concentrando el comportamiento de las mismas en dos grupos diferentes: a) Localidades con economías de perfiles más diversificadas; b) Localidades con base económica preponderantemente turística. Mediante este análisis se pretende alcanzar algunos resultados que, eventualmente complementados con información de carácter primaria tanto cuantitativa como de carácter más cualitativo, aporten al conocimiento de un mercado de trabajo cuyas especificidades lo tornan complejo y cuyas consecuencias preocupan tanto al sector público como al privado

The review and assessment of designated driver programs as an alcohol countermeasure approach. Final report.

National Highway Traffic Safety Administration, Washington, D.C.

Blood Lead Levels in Children and Environmental Lead Contamination in Miami Inner City, Florida

Studies have shown that the environmental conditions of the home are important predictors of health, especially in low-income communities. Understanding the relationship between the environment and health is crucial in the management of certain diseases. One health outcome related to the home environment among urban, minority, and low-income children is childhood lead poisoning. The most common sources of lead exposure for children are lead paint in older, dilapidated housing and contaminated dust and soil produced by accumulated residue of leaded gasoline. Blood lead levels (BLL) as low as 10 μg/dL in children are associated with impaired cognitive function, behavior difficulties, and reduced intelligence. Recently, it is suggested that the standard for intervention be lowered to BLL of 5 μg /dl. The objectives of our report were to assess the prevalence of lead poisoning among children under six years of age and to quantify and test the correlations between BLL in children and lead exposure levels in their environment. This cross-sectional analysis was restricted to 75 children under six years of age who lived in 6 zip code areas of inner city Miami. These locations exhibited unacceptably high levels of lead dust and soil in areas where children live and play. Using the 5 μg/dL as the cutoff point, the prevalence of lead poisoning among the study sample was 13.33%. The study revealed that lead levels in floor dust and window sill samples were positively and significantly correlated with BLL among children (p < 0.05). However, the correlations between BLL and the soil, air, and water samples were not significant. Based on this pilot study, a more comprehensive environmental study in surrounding inner city areas is warranted. Parental education on proper housecleaning techniques may also benefit those living in the high lead-exposed communities of inner city Miami.

Environmental lead contamination in Miami inner-city area

The purpose of the study was to evaluate the magnitude of environmental lead contamination in the downtown area of Miami. Lead inspections took place at 121 homes in Little Haiti and Liberty City and involved the collection ofrepresentative samples from floors, window wells, tap water, soil and air. Community health workers (CHWs) trained in interview and safety techniques went from door to door to enlist participation. On-site investigations were tailored to areas most utilized by children underthe age of6 years. The presence of lead-containing paint was also investigated in situ via X-ray fluorescence (XRF) analysis. Results: Of the sampling areas, the window wells area had the most abundant occurrence of lead. On analysis, 24% of sites returned window well samples with lead levels above Department of Housing and Urban Development (HUD) guidelines. Of the soil samples, the playgrounds around the house had the highest concentration of lead. Soil sampling demonstrated that 27.5% of sites returned samples with lead levels (400 to 1600 ppm) inexcess of HUD/Environmental Protection Agency (EPA) standards. Positive XRF readings in one or more components were returned by 18% of sites. Conclusions: More than half of the houses in these two neighborhoods exhibited unacceptably high levels of lead dust and soil in areas where children live and play. Limitations of this study did not allow the assessment of how many children in this area are affected. A more comprehensive study including other areas of Miami-Dade County with older housing stock is recommended.

Industrial Discharges of Metals in Kigali, Rwanda, and the Impact on Drinking Water Quality

Rwanda is a landlocked country located in Africa's Central-East Great Lakes region. It has a population of 7.5 million which occupies 26,338 km'. Its population density (285/km') is one of the highest in the world and has prompted fear of a rapid degradation of the ecosystem. There are no central sewer systems in Rwanda. The use of pit latrines and septic tanks is common in urban and rural areas. People still defecate in the fields (World Bank, 1989). Less than half of the urban population is served by a central water supply. The majority of people get their water untreated from rivers that have been polluted by chemicals and human excreta. In and around the capital city of Kigali, there is a concentration of people, farms, and industries which discharge wastewater into the Nyabarongo River and its tributaries. The Nyabarongo River, a tributary of the Nile, empties into the Akagera River which flows into Lake Victoria. Nyabarongo River water is used for drinking water, cooking, bathing, and agriculture in the Kigali area. There has been very little monitoring of the water quality of the Nyabarongo River and of industrial outfalls located on tributaries of the Nyabarongo River. As a first step in understanding the water quality of the Nyabarongo River, wastewater samples were collected in 1993 from industrial outfalls located on tributaries of the Nyabarongo River. Most of the facilities sampled had no wastewater treatment. The impact of these discharges on the water quality of the Nyabarongo River was evaluated.

Impact of Water Supply and Sanitation on Diarrheal Morbidity among Young Children in the Socioeconomic and Cultural Context of Rwanda (Africa)

This project studied the frequency and of water contamination at the source, during transportation, and at home to determine the causes of contamination and its impact on the health of children aged 0 to 5 years. The methods used were construction of the infrastructure for three sources of potable water, administration of a questionnaire about socioeconomic status and sanitation behavior, anthropometric measurement of children, and analysis of water and feces. The contamination, first thought to be only a function of rainfall, turned out to be a very complex phenomenon. Water in homes was contaminated (43.4%) with more than 1100 total coliforms/100 ml due to the use of unclean utensils to transport and store water. This socio-economic and cultural problem should be ad- dressed with health education about sanitation, The latrines (found in 43.8% of families) presented a double-edged problem. The extremely high population density reduced the surface area of land per family, which resulted in a severe nutritional deficit (15% of the children) affecting mainly young children, rendering them more susceptible to diarrhea (three episodes/child/year).

Reverse Engineering of Modified Genes by Bayesian Network Analysis Defines Molecular Determinants Critical to the Development of Glioblastoma

In this study we have identified key genes that are critical in development of astrocytic tumors. Meta-analysis of microarray studies which compared normal tissue to astrocytoma revealed a set of 646 differentially expressed genes in the majority of astrocytoma. Reverse engineering of these 646 genes using Bayesian network analysis produced a gene network for each grade of astrocytoma (Grade I–IV), and ‘key genes’ within each grade were identified. Genes found to be most influential to development of the highest grade of astrocytoma, Glioblastoma multiforme were: COL4A1, EGFR, BTF3, MPP2, RAB31, CDK4, CD99, ANXA2, TOP2A, and SERBP1. All of these genes were up-regulated, except MPP2 (down regulated). These 10 genes were able to predict tumor status with 96–100% confidence when using logistic regression, cross validation, and the support vector machine analysis. Markov genes interact with NFkβ, ERK, MAPK, VEGF, growth hormone and collagen to produce a network whose top biological functions are cancer, neurological disease, and cellular movement. Three of the 10 genes - EGFR, COL4A1, and CDK4, in particular, seemed to be potential ‘hubs of activity’. Modified expression of these 10 Markov Blanket genes increases lifetime risk of developing glioblastoma compared to the normal population. The glioblastoma risk estimates were dramatically increased with joint effects of 4 or more than 4 Markov Blanket genes. Joint interaction effects of 4, 5, 6, 7, 8, 9 or 10 Markov Blanket genes produced 9, 13, 20.9, 26.7, 52.8, 53.2, 78.1 or 85.9%, respectively, increase in lifetime risk of developing glioblastoma compared to normal population. In summary, it appears that modified expression of several ‘key genes’ may be required for the development of glioblastoma. Further studies are needed to validate these ‘key genes’ as useful tools for early detection and novel therapeutic options for these tumors.

Hypertension, poor glycemic control, and microalbuminuria in Cuban Americans with type 2 diabetes

Purpose: To investigate to what degree the presence of hypertension (HTN) and poor glycemic control (GC) influences the likelihood of having microalbuminuria (MAU) among Cuban Americans with type 2 diabetes (T2D).Methods: A cross-sectional study conducted in Cuban Americans (n = 179) with T2D. Participants were recruited from a randomly generated mailing list purchased from KnowledgeBase Marketing, Inc. Blood pressure (BP) was measured twice and averaged using an adult size cuff. Glycosylated hemoglobin (A1c) levels were measured from whole blood samples with the Roche Tina-quant method. First morning urine samples were collected from each participant to determine MAU by a semiquantitative assay (ImmunoDip).Results: MAU was present in 26% of Cuban Americans with T2D. A significantly higher percentage of subjects with MA had HTN (P = 0.038) and elevated A1C (P = 0.002) than those with normoalbuminuria. Logistic regression analysis showed that after controlling for covariates, subjects with poor GC were 6.76 times more likely to have MAU if they had hypertension compared with those without hypertension (P = 0.004; 95% confidence interval [CI]: 1.83, 23.05). Conclusion: The clinical significance of these findings emphasizes the early detection of MAU in this Hispanic subgroup combined with BP and good GC, which are fundamentals in preventing and treating diabetes complications and improving individuals’ renal and cardiovascular outcomes.

Cognitive performance and the thymus among HIV-infected subjects receiving HAART

Objective: To evaluate the impact of alcohol use, which is widespread in human immunodeficiency virus (HIV)+ individuals, on highly active antiretroviral therapy (HAART)-associated immune and cognitive improvements and the relationship between those two responses. Methods: In a case-control longitudinal study, thymic volume, cognition, and immune responses were evaluated at baseline and after 6 months therapy in HIV+ and HIV- controls. Cognitive performance was evaluated using the HIV Dementia Score (HDS) and the California Verbal Learning Test (CVLT). Results: Prior to HAART, thymic volume varied considerably from 2.7 to 29.3 cm3 (11 ± 7.2 cm3). Thymic volume at baseline showed a significantly inverse correlation with the patient’s number of years of drinking (r2 = 0.207; p < 0.01), as well as HDS and the CVLT scores in both HIV-infected (r2 = 0.37, p = 0.03) and noninfected (r2 = 0.8, p = 0.01). HIV-infected individuals with a small thymic volume scored in the demented range, as compared with those with a larger thymus (7 ± 2.7 vs. 12 ± 2.3, p = 0.005). After HAART, light/moderate drinkers exhibited thymus size twice that of heavy drinkers (14.8 ± 10.4 vs. 6.9 ± 3.3 cm3). Conclusions: HAART-associated increases of thymus volume appear to be negatively affected by alcohol consumption and significantly related to their cognitive status. This result could have important clinical implications.