Flora of Guatemala / Dorothy L. Nash ; Cucurbitacae contributed by Jennie V.A. Dieterle.

v.24:pt.11:no.4(1976)

Flora of Guatemala / Dorothy L. Nash, Louis O. Williams ; genera contributed by Kenneth M. Becker ... [et al.].

v.24:pt.12(1976)

Pteridophyta of Peru. Rolla M. Tryon, Robert G. Stolze ; contributed by Alan R. Smith.

n.s. no.29(1992)

Domain shuffling in a sensor protein contributed to the evolution of insect pathogenicity in plant-beneficial Pseudomonas protegens.

Pseudomonas protegens is a biocontrol rhizobacterium with a plant-beneficial and an insect pathogenic lifestyle, but it is not understood how the organism switches between the two states. Here, we focus on understanding the function and possible evolution of a molecular sensor that enables P. protegens to detect the insect environment and produce a potent insecticidal toxin specifically during insect infection but not on roots. By using quantitative single cell microscopy and mutant analysis, we provide evidence that the sensor histidine kinase FitF is a key regulator of insecticidal toxin production. Our experimental data and bioinformatic analyses indicate that FitF shares a sensing domain with DctB, a histidine kinase regulating carbon uptake in Proteobacteria. This suggested that FitF has acquired its specificity through domain shuffling from a common ancestor. We constructed a chimeric DctB-FitF protein and showed that it is indeed functional in regulating toxin expression in P. protegens. The shuffling event and subsequent adaptive modifications of the recruited sensor domain were critical for the microorganism to express its potent insect toxin in the observed host-specific manner. Inhibition of the FitF sensor during root colonization could explain the mechanism by which P. protegens differentiates between the plant and insect host. Our study establishes FitF of P. protegens as a prime model for molecular evolution of sensor proteins and bacterial pathogenicity.

Previous contact with Strongyloides venezuelensis contributed to prevent insulitis in MLD-STZ diabetes

Epidemiological and experimental studies support the idea that helminth infections can induce a protective effect against the development of autoimmune and allergic diseases. In this study we characterized the immune response induced by Strongyloides venezuelensis infection in C57BL/6 mice and then evaluated the effect of a previous contact with this helminth in the outcome of type 1 diabetes. Animals were initially infected with 2000 L3 larvae from S. venezuelensis and euthanized 22. days later. An acute phase, identified by a high amount of eggs per gram of feces, was established between days 7 and 9 post-infection. Recovery from infection was associated with a Th2 polarized response characterized by a significant level of serum IgG1 specific antibodies and also a significant production of IL-5 and IL-10 by spleen cells stimulated with S. venezuelensis soluble antigen. Immunization with soluble S. venezuelensis antigen associated with complete Freund's adjuvant followed by infection with S. venezuelensis protected mice from diabetes development induced by streptozotocin. Protection was characterized by a higher body weight gain, lower glycemic levels, much less severe insulitis and preserved insulin production. Together, these results indicate that S. venezuelensis contributed to protect C57BL/6 mice against experimental diabetes induced by streptozotocin. © 2013 Elsevier Inc.

The Jews in India and Far East : (being a reprint of articles contributed to "Church and Synagoge" with appendices)

by J. Henry Lord

List of benefactors who contributed to replacement of books and philosophical apparatus, May 4, 1764

This document lists the names of subscribers who promised funds towards the rebuilding of the library and philosophical apparatus. Entries are divided among three columns, "Apparatus," "Library," and "At large," and include the donor's name and amount promised. Gifts to the library included actual books as well as funds for book purchases.

List of benefactors who contributed to replacement of books and philosophical apparatus, 1765

This document lists the names of subscribers who promised funds towards the rebuilding of the library and philosophical apparatus. Entries are divided among three columns, "Apparatus," "Library," and "At large," and include the donor's name and amount promised. Gifts to the library included actual books as well as funds for book purchases.

Parasites : articles contributed to Wood's reference handbook of the medical sciences, new series, 1900-1904.

Mode of access: Internet.

Favorite dishes contributed by the Daughters of the American Revolution /

Includes index.

Choice recipes : contributed by the Women's Society of the Fairmount Presbyterian Church.

Includes household hints; sample menus; recipes for French, Swedish, German, Chinese, and Italian dishes; sample recipes: Frozen cheese salad, Chicken chow mein, Buster Brown cake.