1000 resultados para Connecticut. Governor (1812-1817 : Smith)


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"First published in the Boston patriot."

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OBJECTIVE Catecholamines released from β-adrenergic neurons upon stress can interfere with periodontal regeneration. The cellular mechanisms, however, are unclear. Here, we assessed the effect of catecholamines on proliferation of periodontal fibroblasts. METHODS Fibroblasts from the gingiva and the periodontal ligament were exposed to agonists of the β-adrenergic receptors; isoproterenol (ISO, non-selective β-adrenergic agonist), salbutamol (SAL, selective β2-adrenergic receptor agonist) and BRL 37344 (BRL selective β3-receptor agonist). Proliferation was stimulated with platelet-derived growth factor-BB (PDGF-BB). Pharmacological inhibitors and gene expression analysis further revealed β-adrenergic signalling. RESULTS Gingiva and periodontal ligament fibroblast express the β2-adrenergic receptor. ISO and SAL but not BRL decreased proliferation of fibroblasts in the presence of PDGF-BB. The inhibitory effect of β-adrenergic signalling on proliferation but not protein synthesis in response to PDGF-BB was reduced by propranolol, a non-selective β-adrenergic antagonist. CONCLUSIONS These results suggest that β2-receptor agonists can reduce the mitogenic response of periodontal fibroblasts. These data add to the compelling concept that blocking of β2-receptor signalling can support tissue maintenance and regeneration.

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The bound notebook contains academic texts copied by Harvard student Jonathan Trumbull in 1724 and 1725. The volume includes transcriptions of Harvard Instructor Judah Monis' Hebrew Grammar, Tutor William Brattle's Compendium of Logic, and Fellow Charles Morton's Natural Logic.

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t. 1. Liricheskīi͡a stikhotvorenīi͡a (1812-1817) -- t. 2. Liricheskīi͡a stikhotvorenīi͡a (1818-1820). Ruslan i Li͡udmila (1817-1820). Kavkazskīĭ Pli͡ennik (1820-1821) -- t. 3. Liricheskīi͡a stikhotvorenīi͡a (1821-1824). Bratʹi͡a razboĭniki (1821-1822). Otryvki iz poėmy (1822). Bakhchisaraĭskīĭ fontan (1822-1823). T͡Sygany (1823-1824).

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Vol. [9-10] have imprint: Prag, In der Schönfeld'schen kaiserl. konigl. Hofbuchdruckerey.

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Vol. 1 has French words with Armenian definitions; v. 2 has Armenian words with French definitions.