Inclusão de estudantes com deficiência no Instituto Federal da Paraíba a partir da ação TEC NEP

The current research developed in the Federal Institute of Paraíba – IFPB, João Pessoa Câmpus, aimed at analyzing the inclusion of students with disabilities in undergraduate courses based on the TEC NEP Action. It departs from the discussion about professional and special education in an inclusive perspective, focusing on people with disabilities, in the social context of these two modalities of education, considering the world scenario and the current Brazilian educational policy. It discusses the TEC NEP Action within the national and local context through the analysis of the official documents with the objective of getting familiarized and evaluating the process of educational inclusion in the IFPB João Pessoa Câmpus. The theoretical reference used contributed to the analysis of the policy which focused on inclusion in federal undergraduate institutions for professional education. The methodology used presents a qualitative analysis, having as subject of the research students with disabilities from undergraduate courses in the IFPB João Pessoa Câmpus who are supported by NAPNE. The results based on the analyzed data show that volunteer students from this research evaluate their process of inclusion in the appointed institution as positive, in spite of challenges specially the ones related to architectural barriers. It is concluded that the foundation of the House for Supporting People with Special Education Needs – (NAPNE) through the TEC NEP Action had crucial importance in the basis for the discussion about inclusion in the institution, widening the vision towards the demands of students with disabilities in order to facilitate access, permanence and academic success of these students.

A atuação dos núcleos de apoio às pessoas com necessidades educacionais especiais no IFRN

The aim of this study was to evaluate the reality of the Service Centers for People with Special Educational Needs (NAPNEs) implanted at Instituto Federal de Educação, Ciência e Tecnologia do Rio Grande do Norte (IFRN) through a Professional Education Program in Technology for People with Special Educational Needs (TEC NEP Program). To reach the proposal we opted for an exploratory research with a qualitative approach characterized as a field of study. Data were obtained from questionnaires answered by thirteen (13) NAPNEs coordinators of different IFRN campuses and examined using content analysis. The survey results show that the creation of the TEC NEP program was an important step for inclusion policies in IFRN. However, difficulties were also identified by participants as coordinators: lack of physical infrastructure, human and material resources and financial matters, among others, as barriers to implementation and performance of NAPNEs. Keywords: TEC NEP Program, Professional Education, Inclusion, People with disabilities.

Expression and activity profiles of DPP IV/CD26 and NEP/CD10 glycoproteins in the human renal cancer are tumor-type dependent

Background: Cell-surface glycoproteins play critical roles in cell-to-cell recognition, signal transduction and regulation, thus being crucial in cell proliferation and cancer etiogenesis and development. DPP IV and NEP are ubiquitous glycopeptidases closely linked to tumor pathogenesis and development, and they are used as markers in some cancers. In the present study, the activity and protein and mRNA expression of these glycoproteins were analysed in a subset of clear-cell (CCRCC) and chromophobe (ChRCC) renal cell carcinomas, and in renal oncocytomas (RO). Methods: Peptidase activities were measured by conventional enzymatic assays with fluorogen-derived substrates. Gene expression was quantitatively determined by qRT-PCR and membrane-bound protein expression and distribution analysis was performed by specific immunostaining. Results: The activity of both glycoproteins was sharply decreased in the three histological types of renal tumors. Protein and mRNA expression was strongly downregulated in tumors from distal nephron (ChRCC and RO). Moreover, soluble DPP IV activity positively correlated with the aggressiveness of CCRCCs (higher activities in high grade tumors). Conclusions: These results support the pivotal role for DPP IV and NEP in the malignant transformation pathways and point to these peptidases as potential diagnostic markers.

一种TEC地图构建方法与全球电子总含量的气候学研究

Global positioning system (GPS) can not only provide precise service for navigation and timing, but also be used to investigate the ionospheric variation. From the GPS observations, we can obtain total electron content (TEC), so-called GPS TEC, which is used to characterize the ionospheric structure. This thesis mainly concerns about GPS TEC data processing and ionospheric climatological analysis as follows. Firstly, develop an algorithm for high-resolution global ionospheric TEC mapping. According to current algorithms in global TEC mapping, we propose a practical way to calibrate the original GPS TEC with the existing GIM results. We also finish global/local TEC mapping by model fitting with the processed GPS TEC data; in practice, we apply it into the local TEC mapping in Southeast of China and obtain some initial results. Next, suggest a new method to calculate equivalent ionospheric global electron content (GEC). We calculate such an equivalent GEC with the TEC data along the geographic longitude 120°E. With the climatological analysis, we can see that GEC climatological variation is mainly composed of three factors: solar cycle, annual and semiannual variations. Solar cycle variation is dominant among them, which indicates the most prominent influence; both annual and semiannual variations play a secondary role and are modulated by solar activity. We construct an empirical GEC model driven by solar activity and seasonal factors on the basis of partial correlation analysis. Generally speaking, our researches not only show that GPS is advantageous in now-casting ionospheric TEC as an important observation, but also show that GEC may become a new index to describe the solar influence on the global ionosphere since the great correlation between GEC and solar activity factor indicates the close relationship between the ionosphere and solar activity.

电离层垂直TEC映射函数的实验观测与统计特性

When used in the determining the total electron content (TEC), which may be the most important ionospheric parameter, the worldwide GPS observation brings a revolutionary change in the ionospheric science. There are three steps in the data processing to retrieve GPS TEC: (1) to estimate slant TEC from the measurements of GPS signals; (2) to map the slant TEC into vertical; and (3) to interpolate the vertical TEC into grid points. In this scientific dissertation we focus our attention on the second step, the mapping theory and method to convert slant TEC into vertical. This is conventionally done by multiplying on the slant TEC a mapping function which is usually determined by certain models of electron density profile. Study of the vertical TEC mapping function is of significance in GPS TEC measurement. This paper first reviews briefly the three steps in GPS TEC mapping process. Then we compare the vertical TEC mapping function which were respectively calculated from the electron density profiles of the ionospheric model and retrieved from the observation of worldwide GPS TEC. We also perform the statistical analysis on the observational mapping functions. The main works and results are as follows: 1. We calculated the vertical TEC mapping functions for both SLM and Chapman models, and discussed the modulation of the ionosphere height to the mapping functions. We use two simple models, single layer model (SLM) and Chapman models, of the ionospheric electron density profiles to calculate the vertical TEC mapping function. In the case of the SLM, we discuss the control of the ionospheric altitude, i.e., the layer height hipp, to the mapping function. We find that the mapping function decreases rapidly as hipp increases. For the Chapman model we study also the control mapping function by both ionospheric altitude indicated by the peak electron density height hmF2, and the scale height, H, which present the thickness of the ionosphere. It is also found that the mapping function decreases rapidly as hmF2 increases. and it also decreases as H increases. 2. Then we estimate the mapping functions from the GPS observations and compare them with those calculated from the electron density models. We first, proposed a new method to estimate the mapping functions from GPS TEC data. This method is then used to retrieve the observational mapping function from both the slant TEC (TECS) provided by International GPS Service (IGS）and vertical TEC provide by JPL Global Ionospheric Maps (GIMs). Then we compare the observational mapping function with those calculated from the electron density models, SLM and Chapman. We find that the values of the observational mapping functions are much smaller than that from the model mapping functions, when the zenith angle is large enough. We attribute this to the effect of the plasmasphere which is above about 1000 km. 3. We statistically analyze the observational mapping functions and reveal their climatological changes. Observational mapping functions during 1999-2007 are used in our statistics. The main results are as follows. (1) The observational mapping functions decrease obviously with the decrement of the solar activity which is represented by the F10.7 index; (2) In annual variations of the observational mapping functions, the semiannual component is found at low-latitudes, and the remarkable seasonal variations at mid- and high-latitudes. (3) The diurnal variation of the observational mapping functions is that they are large in daytime and small at night, they become extremely small in the early morning before sunrise. (4) The observational mapping functions change with latitudes that they are smaller at lower latitudes and larger at higher. All of the above variations of the observational mapping functions are explained by the existence of the plasmasphere, which changes more slowly with time and more rapidly with latitude than the ionosphere does . In summary, our study on the vertical TEC mapping function imply that the ionosphere height has a modulative effect on the mapping function. We first propose the concept of the 'observational mapping functions' , and provide a new method to calculate them. This is important in improving the TEC mapping. It may also possible to retrieving the plasmaspheric information from GPS observations.

Quality of TEC Estimated with Mod Ion Using GPS and GLONASS Data

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Correcão ionosférica utilizando os MAPAS: Globais do TEC DO IGS: Avaliação no posicionamento por ponto na região brasileira

One of the main drawbacks of the GPS accuracy for L1 users is the error due to ionosphere. This error depends on the total electron content presents in the ionosphere, as well as of the carrier frequency. Some models have been developed to correct GPS observables of the systematic error due to the ionosphere. The model more known and used is the Klobuchar model, which corrected 50-60% of the ionospheric error approximately. Alternatively, IGS (International GNSS Service) also has developed a model called Global Ionospheric Map (GIM). These maps, in format IONEX, are available in the site of the IGS, and one of the applications of them is to correct the GPS observables of the error due to ionosphere. This work aims at evaluating the quality of GPS point positioning using the IGS ionospheric model in the Brazilian region. Tests carried out had shown an average improvement in the horizontal and vertical determination of 72% and 26%, respectively, when GIM is used in the point positioning.

Diagnostics of equatorial and low latitude ionosphere by TEC mapping over Brazil

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Heterodox Economics and Dissemination of Research through the Internet: the Experience of RePEc and NEP

We study how the democratization of the diffusion of research through the Internet could have helped non traditional fields of research. The specific case we approach is Heterodox Economics as its pre-prints are disseminated through NEP, the email alert service of RePEc. Comparing heterodox and mainstream papers, we find that heterodox ones are quite systematically more downloaded, and particularly so when considering downloads per subscriber. We conclude that the Internet definitely helps heterodox research, also because other researcher get exposed to it. But there is still room for more participation by heterodox researchers.