Educación y sociedad del conocimiento.

Resumen tomado de la revista.

Role of NOD2 variants in spondylarthritis

Objective. To investigate the role of the gene NOD2 in susceptibility to, and clinical manifestations of, ankylosing spondylitis (AS). Methods. A case-control study of NOD2 polymorphisms known to be associated with Crohn's disease (CD) (Pro268 Ser, Arg702 Trp, GlY908 Arg, and Len1007fsinsC) was performed in 229 cases of primary AS with no diagnosed inflammatory bowel disease (IBD), 197 cases of AS associated with IBD (referred to as colitic spondylarthritis; comprising 78 with CD and 119 with ulcerative colitis [UC]), and 229 ethnically matched, healthy controls. Associations between NOD2 polymorphisms and several clinical features of AS, including disease severity assessed by questionnaire and age at spondylarthritis onset, were also investigated. Exclusion linkage mapping of chromosome 16 was performed in a separate group of 185 multicase families with AS. Results. An association was identified between Gly908 Arg and UC spondylarthritis (P = 0.016, odds ratio [OR] 4.6, 95% confidence interval [95% CI] 1.316), and a nonsignificant trend with a similar magnitude was observed in association with CD spondylarthritis (P = 0.08, OR 3.9, 95% CI 0.8-18). The Pro268Ser variant was inversely associated with UC spondylarthritis (P = 0.003, OR 0.55, 95% CI 0.37-0.82), but not with CD spondylarthritis. No association was demonstrated between NOD2 variants and primary AS, or between other variants of NOD2 and either UC or CD spondylarthritis. Carriage of the Pro268 Ser polymorphism was associated with greater disease activity as measured by the Bath Ankylosing Spondylitis Disease Activity Index (P = 0.002). Although patients with CD had a younger age at spondylarthritis onset than did those with UC (22.4 years versus 26.4 years; P = 0.01), no association was noted between the NOD2 variants linked with CD and age at spondylarthritis onset. In primary AS, the presence of a gene with a magnitude of association >2.0 was excluded (exclusion logarithm of odds score less than -2.0), and no association was observed with the microsatellite D16S3136. Conclusion. NOD2 variants do not significantly affect the risk of developing primary AS, but may influence susceptibility to, and clinical manifestations of, colitic spondylarthritis.

东灵山森林生态系统若干水分问题的研究

东灵山地区年均降水量659.7mm，单次降水以雨量小、雨强低的降水为主。水汽压（年均17.7mb）、相对湿度（年均66％）的季节变化呈现生长季高、冬季低的趋势。年均蒸发量1019.5mm;气温、风速、日照时间和水压与月蒸发量和日蒸量相关显著;气温、日照时间和水压分别在11-6月、7－8月和9－10月为决定蒸发量的首要因子。枯枝落叶层、土壤层湿度主要受前十日降水量和坡向影响。 植物体含水量生长季节较高，冬季较低;含水量随径级的增大而降低。六个灌木树种的平均含水量大小顺序为：毛榛（48.62%）最高荆条（36.32%）最低;七个乔木树种水分含量为油松，56.14%;蒙椴，54.19%;华北落叶松，52.91%;五角枫，43.64%;辽东栎，41.87%;棘皮桦，41.13%;大叶白腊，37.79%。几种植被类型的储水量为：辽东栎林，82.08mm;华北落叶松林，47.35mm;混交林，34.60mm;油松林，31.33mm;灌丛，12.40mm。各树种叶片日最低水势的季节均值为：辽东栎，-16.1bar;五角枫，-15.8bar;大叶白腊，-15.1bar;糠椴，-13.4bar;棘皮桦，-12.3bar;蒙椴，-12.2bar。叶片水势的日间变化均呈一“V”形曲线;光照在叶片水势的日间变化中起着决定性作用。 96年各树种平均单株树干茎流量为辽东栎，30.3mm(4.19%);华北落叶松，16.1mm(2.22%);油松，8.9mm(1.23%);棘皮桦，2.9mm(0.40%)。两个生长季各林分冠层的水量平衡为：辽东栎林，树干流茎量101.87mm(9.18%)，穿透降水量823.08mm(74.15%)，截留量185.05mm(16.67%);华北落叶松林，树干径流量66.88mm(6.03%)，穿透降水量836.92mm(75.40%)，截留量206.20mm(18.58);混交林，树干径流量50.13(4.52%)，穿透降水量846.78mm(76.29%)，截留量212.20mm(19.12%);油松林，树干径流量33.90mm(3.05%)，穿透降水量934.88mm(84.22%)，截留量141.22mm(12.72%)。多元回归分析表明，树干流茎量S与降水量P和前24小时降水量P_1呈显著正相关关系;穿透降水量T与降水量P和最大雨强M正相关显著。附加截留量与降水时间成正比。 枯枝落叶层的生物量为：油松林，25.56t/hm~2;华北落叶松林20.01t/hm~2;辽东栎林，8.31t/hm~2;混交林，7.98t/hm~2。枯枝落叶层的平均实际持水量和有效持水量均以油松林最大，其次是华北落叶松林，而混交林和辽东栎林较低;枯枝落叶层的实际持水量和有效持水量的季节变化分别与前十日降水量P10成正相关和负相关关系。枯枝落叶层的截留量为油松林＞华北落叶松林＞辽东栎林＞混交林;油松林（145.632mm和90.800mm）混交林(61.816mm和54.504mm)。油松林、辽东栎林、混交林和华北落叶松林去除枯枝落叶层后，土壤入渗量比对照平均降低100mm以上;表层土壤含水量分别比对照土壤下降了6.26、18.26、15.06和15.07个百分点。地表径流量分别增加了，辽东栎林34.299mm(603%)和15.816mm(525%);油松林14.593mm(732%)和10.584mm(1321%);混交林12.004mm(181%)和7.275mm(364%);华北落叶松林3.555mm(118%)，3.275mm(229%)。96年生长季，各土壤流失量分别增加了：油松林172.751t/hm~2(124倍);辽东栎林836.500t/hm~2(119倍);混交林172.499t/hm~2(47倍);华北落叶松林11.557t/hm~2(11倍)。表层土壤容重分别增加了：油松林15.0%和20.6%，辽东栎林18.4%和28.2%，混交林11.5%和38.5%，华北落叶松林4.3%和17.1%。 0-60cm深度土壤容重平均值的大小顺序为：草地>灌丛>辽东栎林>油松林>混交林>华北落叶松林;而土壤孔隙度的大小顺序为华北落叶松林>混交林>油松林>辽东栎林>灌丛>草地。两个生长季为土壤实际储水量的均值：油松林，124.45mm，78.62mm;辽东栎林，131.23mm，87.72mm;混交林，180.41mm，113.90mm;华北落叶松林，165.53mm，127.95mm;灌丛，172.50mm，89.81mm;草地，152.92mm，89.59 mm分别比干旱年份97年高出45.83mm、43.51mm、51.63mm、37.58mm、82.69mm和63.33mm。两个生长季的地表径流量为草地，30.930mm(2.79%);灌丛，16.321mm(147%);油松林，2.911mm(0.26%);辽东栎林，8.703mm(0.78%);混交林，8.625mm(0.78%);华北落叶松林，4.447mm(0.40%)。油松林、混交林和华北落叶松林地表径流量与降水量P(mm)和最大雨强(mm/h)正相关显著;而辽东栎林、灌丛和草地的地表径流量则与降水量P(mm)、平均雨强Q(mm/hr)和最大雨强M(mm/hr)三者之间呈显著正相关关系。与草地相比(1220.093kg/hm~2，100％)，灌丛、辽东栎林、混交林、油松林和华北落叶松林96年生长季的土壤流失量分别降低了85.05%、94.26%、96.99%、98.86和99.14%。 降水量是影响小流域径流量时间变化的主要因素;南沟和马牙石沟96年的径流量分别是97年的8.19倍和7.87倍，而径流深(46.25mm，52.75mm)分别比97年(5.65mm,6.70mm)高出40.60mm和46.05mm。两个小流域由于面积的差异而使南沟两年的径流量分别比马牙石沟高出2773.136m~3(13.15%)和235.434m~3(8.79%)。96年和97年马牙石沟径流深比南沟高出6.5mm(14.05%)和1.05mm(18.58%)。在地处大陆性季风气候区的东灵山地区，用0.010m~3/min/km~2/hr能较好地分割小流域的洪峰和基流。在五次暴雨水文曲线中，马牙石沟的快速径流量分别比南沟高出25.00%到143.33%。五次洪水水文响应R的平均值南沟为0.218%，马牙石沟为0.404%;与海洋性气候地区相比，东灵山地区小流域的R值要低一到两个数量级。马牙石沟洪峰流量Qp的平均值为418.772L/min要比南沟(281.191L/min)大48.9%。东灵山地区小流域的洪水径流过程可分为三种类型。

Quality aspects of some exportable dried fishery products of Bangladesh

A study was conducted to evaluate the quality aspects of eight exportable dried fishery products of Bangladesh. The products were evaluated by examining organoleptic properties, water reconstitution behavior, microbiological and biochemical aspects. The water reconstitution rate was faster in ribbon fish and Bombay duck, and slower in other fishes and air bladder and shark fin products. Organoleptic and physical characteristics in respect of color, odor, texture, insect infestation and broken pieces of the products revealed that all of the products were either in excellent or acceptable condition. Total viable bacterial load ranged from 0.95 x 104 CFU/g to 1.8 x 104 CFU/g in dried products. Coliform bacteria was absent in all the dried fishery products. The results of moisture, crude protein, lipid and ash content of the products ranged from 16.20 to 23.51%, 58.37 to 82.86%, 0.17 to 14.44% and 0.58 to 9.23%, respectively. Non-protein nitrogen (NPN) contents were in the range of 0.104 to 2.372% and the pepsin digestibility values were of 88.41 to 94.23%. The results of the study suggested that the exportable dried products were of good quality and hygienically safe.

子午岭地区林地破坏加速侵蚀对土壤养分流失和微生物的影响研究

以浅沟集水区为研究对象,分析了子午岭地区林地被开垦破坏15年后裸露地在不同侵蚀强度和侵蚀方式下的土壤养分流失和土壤微生物数量的变化。结果表明,林地开垦破坏后,土壤侵蚀加剧发展,侵蚀强度达159.7t/(hm2.a),是林地土壤侵蚀量的上千倍。开垦破坏15年后,裸露地浅沟集水区不同地形部位表层土壤全氮、有机碳、速效磷和土壤微生物总数显著减少,同林地相比,依次分别减少37.9%~82.6%、42.7%~86.4%、24.2%~80.3%和31.8%9~2.0%。在裸露地浅沟集水区梁坡随坡长的增加,表层土壤有机碳、全氮和速效磷含量及微生物总数呈显著的下降趋势,且沟槽的土壤各养分含量及微生物总数明显低于沟间。裸露地浅沟集水区土壤养分流失强度及微生物数量减少幅度在浅沟集水区的空间分布与土壤侵蚀方式和侵蚀强度相对应。林地开垦破坏15年后,土壤养分以有机碳流失最严重,其次分别为速效磷、全氮;微生物中的真菌减少幅度最大,细菌次之,放线菌减少幅度最小。

江河源区高山嵩草草甸覆被变化对植物群落特征及多样性的影响

本研究是在青海省达日县青珍乡进行的，分析了高山嵩苹草句不同退化演替阶段覆被变化与植物群落特征、多样性关系。研究结果表明：轻度退化草地、中度退化草地、重度退化草地物种数分别占研究区物种数的58．93％、73．2l％、66、07％。原生植被的优势种高山嵩草随退化程度的加剧而逐渐减少，其优势度分别为27．13％、12．37％、1．82％。物种多样性指数依次为中度退化演替阶段（3．41）〉重度退化演替阶段（3．39）〉轻度退化演替阶段（2．99）；均匀度指数依次为重度退化演替阶段（O．94）〉中度退化演替阶段（0．92）〉轻度退化演替阶段（0．86）。地上生物量中度退化草地最大，轻度退化草地居中，重度退化草地最低。随着退化程度的加剧。禾草类和莎草类植物的生物量减少，而杂类草增加。轻度退化草地地下生物量明显高于退化草地。相关分析表明。植被盖度与土壤含水量之间呈极显著的正相关关系（P〈0．01）。

Prevalence and risk factors of depressive symptoms in a Canadian palliative home care population: a cross-sectional study

Background: Depression in palliative care patients is important because of its intrinsic burden and association with elevated physical symptoms, reduced immunity and increased mortality risk. Identifying risk factors associated with depression can enable clinicians to more readily diagnose it, which is important since depression is treatable. The purpose of this cross-sectional study was to determine the prevalence of depressive symptoms and risk factors associated with them in a large sample of palliative home care patients.

Methods: The data come from interRAI Palliative Care assessments completed between 2006 and 2012. The sample (n = 5144) consists of adults residing in Ontario (Canada), receiving home care services, classified as palliative, and not experiencing significant cognitive impairment. Logistic regression identified the risk factors associated with depressive symptoms. The dependent variable was the Depression Rating Scale (DRS) and the independent variables were functional indicators from the interRAI assessment and other variables identified in the literature. We examined the results of the complete case and multiple imputation analyses, and found them to be similar.

Results: The prevalence of depressive symptoms was 9.8%. The risk factors associated with depressive symptoms were (pooled estimates, multiple imputation): low life satisfaction (OR = 3.01 [CI = 2.37-3.82]), severe and moderate sleep disorders (2.56 [2.05-3.19] and 1.56 [1.18-2.06]), health instability (2.12 [1.42-3.18]), caregiver distress 2.01 [1.62-2.51]), daily pain (1.73 [1.35-2.22]), cognitive impairment (1.45 [1.13-1.87]), being female (1.37 [1.11-1.68]), and gastrointestinal symptoms (1.27 [1.03-1.55]). Life satisfaction mediated the effect of prognostic awareness on depressive symptoms.

Conclusions: The prevalence of depressive symptoms in our study was close to the median of 10-20% reported in the palliative care literature, suggesting they are present but by no means inevitable in palliative patients. Most of the factors associated with depressive symptoms in our study are amenable to clinical intervention and often targeted in palliative care programs. Designing interventions to address them can be challenging, however, requiring careful attention to patient preferences, the spectrum of comorbid conditions they face, and their social supports. Life satisfaction was one of the strongest factors associated with depressive symptoms in our study, and is likely to be among the most challenging to address.

Conduzco, leo y escribo : método de alfabetización. Guía didáctica y solucionario.

Complementa a Conduzco, leo y escribo : método de alfabetización (ISBN 84-505-9591-6)

Informe educativo 2000.

Resumen tomado de la revista

Réquiem por el territorio MEC.

Resumen basado en el que aporta la revista

Aprendiendo a respetar la diversidad : de la escuela a la sociedad.

Hoy en día la sociedad es multicultural y heterogénea, y cada día son más numerosos los hijos de inmigrantes en las aulas. Esto hace necesario llevar a cabo una enseñanza basada en el respeto a lo diferente donde se facilite la interacción cultural en condiciones de igualdad. La escuela debe favorecer el nacimiento de una sociedad global construida por y para todos, sin que esto implique la anulación de las peculiaridades de cada individuo. Se aboga por el aprendizaje cooperativo como una de las mejores formas de promover el equilibrio intercultural. El logro de actitudes de respeto hacia lo culturalmente diferente se puede alcanzar estableciendo puentes de relacion entre la escuela y la sociedad.

ESO y diversidad : comprensión e incomprensión.

La LOGSE extendió la enseñanza obligatoria hasta los dieciséis, pero también se extendieron algunos problemas con ella. Se hace una reflexión sobre estos inconvenientes destacando sobre ellos aspectos concretos. Para hacerles frente se propone actuar en dos niveles: alumnos, profesores y cambio curricular por un lado, y administración, centros y gestión por otro. En cada uno de estos dos campos se plantean los problemas concretos y las posibles soluciones.

Estrategias didácticas activas y reformas educativas : revisión de un problema.

El concepto de activismo hace referencia a unas estrategias activas en la enseñanza, asociadas también a unos componentes de carácter social. La intención reformadora de la enseñanza en España ha estado marcada por el activismo desde sus primeros intentos a finales del siglo XIX con el movimiento de la Escuela Nueva. El autor rastrea los principios de cada una de las reformas habidas en el presente siglo basándose en el marco legal en el que se encuadran. Así, la huella del activismo se hace patente en el cambio brusco que supuso la educación franquista, en los Cuestionarios Nacionales para la Enseñanza Primaria de 1953, en la implantación de las Unidades Didácticas en 1965, con la Ley General de Educación de 1970 y, finalmente, con la reforma propugnada por la LOGSE.