999 resultados para 327.72


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2003年人身取引にかんする議定書の発効を機に人身取引問題への取り組みがグローバル規模の課題となっている。タイは,2006年UNODCの報告によれば,人身取引被害者の出身国,中継国そして到達国としてもっとも高い指標に位置づけられている。本稿は,タイにおける人身取引問題のなかでも,ミャンマーからタイヘの多数の人口の流入が人身取引を誘発する要因のひとつをなしている点に着目し,ミャンマーからタイヘの人身取引問題とタイの移民労働政策との断ちがたい関係を分析し,それに対するタイおよびミャンマーの法的枠組みを考察する。タイにおけるミャンマー人の人身取引被害を労働搾取という観点からアプローチし,人身取引問題の解決には,刑法上の人身取引罪の加害者および被害者として法的手続で処理することに加え,自国の政治的経済的要因によってミャンマーからタイヘ越境し人身取引被害者となった者にとって最善の解決につながる法政策,さらには労働搾取による人身取引被害者をなくすための法政策が不可欠であることを論じる。

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In order to prevent, suppress and punish human trafficking, bilateral agreements between origin of victim countries and destination countries are crucial, because their cooperation involves cross-border activities such as repatriation of victims, extradition of criminals and information-sharing. This article analyzes three bilateral legal instruments between The Government of The Kingdom of Thailand and her three neighboring countries, namely The Royal Government of Cambodia, The Government of Lao People's Democratic Republic and The Government of The Union of Myanmar. The analysis will examine the legal status of the victim, the victim as witness in criminal proceedings, the victim protection programs, the recovery and restitution of damages, the process of repatriating the victim, and the prosecution of the criminal.

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Universidade Estadual de Campinas . Faculdade de Educação Física

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Background: Mutations in TP53 are common events during carcinogenesis. In addition to gene mutations, several reports have focused on TP53 polymorphisms as risk factors for malignant disease. Many studies have highlighted that the status of the TP53 codon 72 polymorphism could influence cancer susceptibility. However, the results have been inconsistent and various methodological features can contribute to departures from Hardy-Weinberg equilibrium, a condition that may influence the disease risk estimates. The most widely accepted method of detecting genotyping error is to confirm genotypes by sequencing and/or via a separate method. Results: We developed two new genotyping methods for TP53 codon 72 polymorphism detection: Denaturing High Performance Liquid Chromatography (DHPLC) and Dot Blot hybridization. These methods were compared with Restriction Fragment Length Polymorphism (RFLP) using two different restriction enzymes. We observed high agreement among all methodologies assayed. Dot-blot hybridization and DHPLC results were more highly concordant with each other than when either of these methods was compared with RFLP. Conclusions: Although variations may occur, our results indicate that DHPLC and Dot Blot hybridization can be used as reliable screening methods for TP53 codon 72 polymorphism detection, especially in molecular epidemiologic studies, where high throughput methodologies are required.

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Compare the clinicoradiological presentation of urogenital tuberculosis (UGT) between immunocompromised and nonimmunocompromised patients. Eighty patients diagnosed with UGT were divided into two groups: eight immunocompromised patients (four with acquired immunodeficiency syndrome [AIDS], and four renal transplant patients on immunosuppressive therapy) and 72 nonimmunocompromised patients. The groups were compared as for age, signs and symptoms, diagnostic approach, pattern of urogenital organ involvement, and early specific mortality (within 6 months from diagnosis). AIDS patients were younger (median age 26 years, range 16-38 years), and renal transplant patients were older (median age 51.5 years, range 45-57 years), compared with the nonimmunocompromised subjects (median age 35 years, range 12-75 years). Immunocompromised patients had greater frequency of fever (87.5% versus 43.1%, P = 0.024), lower frequency of storage symptoms (37.5% versus 76.4%, P = 0.033), shorter length of disease (< 6 months: 87.5% versus 2.8%, P < 0.001), and larger frequency of disseminated tuberculosis (62.5% versus 18.1%, P = 0.012). Predominantly parenchymatous renal involvement was more frequent in immunocompromised patients (87.5% versus 6.2%, P < 0.001), who also had lower frequency of stenosis of the collecting system (12.5% versus 93.8%, P < 0.001) and contracted bladder (12.5% versus 65.3%, P = 0.001). UGT has a different clinicoradiological presentation in immunocompromised patients, with predominance of systemic symptoms, disseminated tuberculosis, multiple parenchymatous renal foci, and lower frequency of lesions of the collecting system. In the context of immunosuppression, UGT behaves as a severe bacterial infection, with bacteremia and visceral metastatic foci.

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Boletim elaborado pela Assessoria de Comunicação e Imprensa da Reitoria da UNESP

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Revista elaborada pela Assessoria de Comunicação e Imprensa da Reitoria da UNESP

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OBJETIVO: Avaliar indicadores de prevalência e severidade de cárie em adolescentes e as necessidades de tratamento. MÉTODOS: Os dados foram obtidos a partir de levantamentos epidemiológicos em saúde bucal realizados no Estado de São Paulo em 1998 e 2002, com adolescentes de 12 e 18 anos de idade. A experiência de cárie foi medida pelo índice de dentes permanentes cariados, perdidos e restaurados (CPOD) e a necessidade de tratamento foi avaliada segundo critérios da Organização Mundial de Saúde. O significant caries index foi empregado para definir a experiência de cárie de um terço do grupo que apresentou maior experiência da doença. Para a idade de 12 anos, os exames ocorreram em escolas públicas e privadas, em 1998 (N=9.327) e 2002 (N=5.782), enquanto que os adolescentes de 18 anos, em 2002, foram examinados em seus domicílios (N=5195, em 1998 e N=257 em 2002). RESULTADOS: Aos 12 anos de idade, o índice CPOD foi de 3,72 em 1998 e de 2,52 em 2002, enquanto que aos 18 anos foi de 8,64 e 7,13, respectivamente. O significant caries index aos 12 anos foi de 7,40 (1998) e 5,62 (2002), aos 18 anos foi de 15,05 e 12,19, respectivamente. Aos 12 anos observou-se aumento de necessidades de restaurações de uma superfície (p<0,0001) e de selantes aos 18 anos (p<0,0001). CONCLUSÕES: Verificou-se que houve declínio da cárie entre os adolescentes e a maioria das necessidades de tratamento odontológicas foram de baixa complexidade.

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ABSTRACT OBJECTIVE To describe the response rate and characteristics of people who either took part or not in from the Study of Cardiovascular Risks in Adolescents (ERICA) , according to information subsets. METHODS ERICA is a school-based, nation-wide investigation with a representative sample of 12 to 17-year-old adolescents attending public or private schools in municipalities with over 100,000 inhabitants in Brazil. Response rate of eligible subjects were calculated according to macro-regions, sex, age, and type of school (public or private). We also calculated the percentages of replacement schools in comparison with the ones originally selected as per the sample design, according to the types of schools in the macro-regions. The subjects and non-subjects were compared according to sex, age, and average body mass indices (kg/m2). RESULTS We had 102,327 eligible adolescents enrolled in the groups drawn. The highest percentage of complete information was obtained for the subset of the questionnaire (72.9%). Complete information regarding anthropometric measurements and the ones from the questionnaire were obtained for 72.0% of the adolescents, and the combination of these data with the 24-hour dietary recall were obtained for 70.3% of the adolescents. Complete information from the questionnaire plus biochemical blood evaluation data were obtained for 52.5% of the morning session adolescents (selected for blood tests). The response percentage in private schools was higher than the one in public schools for most of the combination of information. The ratio of older and male adolescents non-participants was higher than the ratio among participants. CONCLUSIONS The response rate for non-invasive procedures was high. The response rate for blood collection – an invasive procedure that requires a 12-hour fasting period and the informed consent form from legal guardians – was lower. The response rate observed in public schools was lower than in the private ones, and that may reflect lower school frequency of registered students.

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Este trabalho tem por objetivo caracterizar a desnutrição protéico-energética associada a parasitose intestinal em grupo de 149 crianças de ambos os sexos, na faixa etária de 3 a 72 meses, da cidade de Mirassol D'Oeste, na região do Projeto Polonoroeste em Mato Grosso. De cada criança foram coletados os seguintes dados: sexo, peso, idade e amostra de fezes para exame parasitológico. Os dados peso/idade obtidos foram analisados pelos critérios de GOMEZ. Utilizou-se como padrão de referência o National Center for Health Statistic (NCHS). Para diagnóstico dos parasitas intestinais executou-se o método de Hoffman, Pons e Janer. O grupo estudado constitui-se em sua maioria de crianças desnutridas, sendo a forma leve de desnutrição mais comum que as formas moderada e grave. As enteroparasitoses foram encontradas em 69% das amostras examinadas. A "Giardia lamblia" foi o protozoário mais comum e o "Ancilostomídeo" o helminto mais encontrado. O teste X² não mostrou relação de dependência entre o estado nutricional e a freqüência de enteroparasitoses.