972 resultados para potenciais unidimensionais


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The Auditory Evoked Middle Latency Response is one of the most promising objective tests in audiology and in revealing brain dysfunction and neuro-audiologic findings. The main advantages of its clinical use are precision and objectivity in evaluating children. This study aimed to analyze the auditory evoked middle latency response in two patients with auditory processing disorder and relate objective and behavioral measures. This case study was conducted in 2 patients (P1 = 12 years, female, P2 = 17 years old, male), both with the absence of sensory abnormalities, neurological and neuropsychiatric disorders. Both were submitted to anamnesis, inspection of the external ear canal, hearing test and evaluation of Auditory Evoked Middle latency Response. There was a significant association between behavioral test and objectives results. In the interview, there were complaints about the difficulty in listening in a noisy environment, sound localization, inattention, and phonological changes in writing and speaking, as confirmed by evaluation of auditory processing and Auditory Evoked Middle Latency Response. Changes were observed in the right decoding process hearing in both cases on the behavioral assessment of auditory processing; auditory evoked potential test middle latency shows that the right contralateral via response was deficient, confirming the difficulties of the patients in the assignment of meaning in acoustic information in a competitive sound condition at right, in both cases. In these cases it was shown the association between the results, but there is a need for further studies with larger sample population to confirm the data.

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Purpose: To study the components of long latency auditory evoked potentials and to compare data from these measures in students with and without learning disabilities. Method: Thirty students, 15 with learning disorder (study group) and 15 typical without learning problems (control group), of both genders, aged 7-14 years, mean age 10 years. They underwent clinical assessment in a clinic belonging to a public university in the state of São Paulo. Following, audiological assessment was performed to determine normal peripheral auditory system and electrophysiological assessment by examining the long latency auditory evoked response. Result: The results showed that there are functional differences between the groups. Increased latency components of long latency auditory evoked potential was observed in the study group compared to the control group. Longer latency values of these components were observed in the left ear when stimulated in the study group. Conclusion: This study contributed to better understanding of the auditory pathway functioning in children with learning disorders and can be a reference for other clinical and experimental studies and thus improve the definition of diagnostic criteria in this population.

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In the last twenty years, and more expressively in the past decade, the search for improvement in the organ transplantation system has contributed to the achievement of positive results in the Brazilian statistics related to the survival of transplanted individuals. However, for a transplantation to be performed, a number of phases must be followed by professionals working in organ search services. The phase that generates the greatest tension is undoubtedly that of family interviews, as it involves both the feelings of relatives who are facing a recent loss and those of interviewers who need to know how to deal with families at this time. The goal of this study was to apprehend perceptions of professionals working for an Organ Search Organization concerning interviews with relatives of potential donors. The qualitative methodology was used by adopting the Collective Subject Discourse for data organization. Interviews were conducted with six staff members of an organ search service whose experience as interviewers comprised from eight to fourteen years of work. It was possible to apprehend the professionals’ perceptions of family interviews and identify facilitating and hindering factors in this phase of the donation process. Such factors mainly involve: contact with the teams assisting patients, the difficult moment that families are experiencing and the teams’ as well as the institution’s preparation for rendering this type of service. The balance between the offer of and demand for organs in Brazil will only be achieved by means of an efficient and effective structure in transplantation organ search services and increased donation consent rates to be obtained by adequate communication between interviewers and relatives

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A preocupação ambiental em relação aos resíduos de equipamentos elétricos e eletrônicos (REEE) vem crescendo muito nos últimos anos devido à presença de substâncias perigosas que podem causar danos ao ambiente e à saúde. O trabalho teve por objetivo investigar o destino de REEE gerados no Campus Quadrilátero da Saúde/Direito (CQS/D) da Universidade de São Paulo (Faculdade de Medicina, Faculdade de Saúde Pública, Escola de Enfermagem, Instituto de Medicina Tropical e Faculdade de Direito), a partir do momento em que os mesmos deixam as dependências da Instituição e identificar potenciais riscos à saúde e ao ambiente, decorrentes das atuais ações de gerenciamento dos REEE nas unidades estudadas. A pesquisa desenvolveu-se em 3 etapas: a) pesquisa bibliográfica e documental; b) visitas às unidades que compõem o CQS/D, e identificação de cinco intituições filantrópicas como principais destinos; c) visitas aos locais identificados para investigar as atividades desenvolvidas para a recuperação de equipamentos, componentes ou materiais recicláveis, com base em um formulário desenvolvido. Adicionalmente, foram realizadas visitas a outros quatro locais de destino de REEE. Foi identificado que as etapas realizadas nas instituições são: recebimento, teste, conserto e desmontagem manual e que o destino dos REEE pode ser considerado problemático, já que os rejeitos acabam sendo descartados como resíduo comum, podendo causar danos ao ambiente e à saúde. Além disso há riscos ocupacionais, pois os trabalhadores, além de não utilizarem equipamentos de proteção individual necessários, nem sempre recebem capacitação para exercer suas funções

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A descoberta de agentes hipoglicemiantes constitui ainda um grande desafio no tratamento do diabetes, devido ao elevado índice de efeitos adversos e à baixa eficácia dos fármacos existentes. As alfa-glicosidases, enzimas essenciais ao metabolismo dos açúcares, são alvos terapêuticos estratégicos para a descoberta e desenvolvimento de fármacos antidiabéticos. Na busca de novos modelos estruturais com atividade antidiabética, o presente projeto teve como objetivo a síntese de aminochalconas e nitrochalconas como inibidores potenciais de alfaglicosidases. Para atingir o objetivo delineado foi planejada a síntese de 4’-nitrochalconas através da condensação de Claisen-Schmidt, que conduziriam à obtenção das respectivas 4’- aminochalconas na presença de cloreto de estanho II como agente redutor. Ao todo foram sintetizadas 14 substâncias, sendo 6 nitrochalconas e 8 aminochalconas que foram purificadas utilizando-se técnicas cromatográficas tais como Cromatografia em Coluna e Cromatografia em Camada Delgada Preparativa. A identificação espectroscópica foi realizada por Ressonância Magnética Nuclear de 13C e 1H. As chalconas sintetizadas foram avaliadas por meio de ensaios de inibição de alfa-glicosidases de Saccharomyces cerevisiae. As substâncias 10 e 14 apresentaram valores de CI50 (concentração capaz de inibir em 50% a atividade enzimática) de 1,23 e 1,88 μM respectivamente, mostrando-se mais potentes que a acarbose (CI50 4,90 μM), a qual foi empregada como controle positivo. Os dados de CI50 revelaram que a presença de hidroxilas no anel B, bem como a posição e o número desses substituintes é de fundamental importância para a inibição da atividade enzimática. Em contrapartida, a presença de grupos doadores ou receptores de elétrons no anel A é pouco significativa para a inibição de

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The semidecidual forests, as tropical forests, presents zoochoric dispersal syndrome in the most of their plant species, with approximately one third of frugivorous species responsible for the seeds dispersal are birds. The bills width is a limiting factor, it must be equal or bigger than the seeds width, because the viable seeds dispersal depends on leaving the digestive system after been swallowed hole. Birds and plants inventorys were realized in a semidecidual Forest fragment, in Botucatu – SP, called Mata da Bica. After this, the birds consumers of fuits/seeds were selected (frugivorous, granivorous and onivorous) and also the zoochoric plants, both for building a possibilities matrix, to verify the potential seed dispersers according to the seeds and bills width. Going to the matrix end we can observe a decrease in the interaction possibillities, because the seeds width increases and the bills width decreases. It has been observed that 50,7% seeds could be dispersed by all listed birds, because the seeds were narrower than the narrowest bill. In the other way large seeded species, as Holocalix balansae and Hymemaea courbaril has shown only two possible dispersers: Trogon surrucura and Piaya cayana. There are no possible dispersers to Syagrus oleraceae in the matrix. The need for large birds or other animals that works as large seed disperses demand conservation efforts, since most of these animals need big and conserved areas for their life habits

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O crescimento das sociedades urbanas tem gerado um aumento significativo na produção dos resíduos sólidos urbanos, tornando o tema de disposição final amplamente discutido nas gestões públicas. Recentemente, a partir da criação da Lei Federal nº 12.305/2010, que institui a Política Nacional dos Resíduos Sólidos, foi estabelecido que a disposição final ambientalmente adequada dos rejeitos deve ser feita exclusivamente em aterros. O presente trabalho teve então como objetivo a avaliação de áreas potenciais para instalação de aterro sanitário no Distrito de Floresta do Sul no município de Presidente Prudente/SP. Para tanto, utilizou-se o SIG, como ferramenta do geoprocessamento, para análise espacial. Inicialmente, construiu-se um banco de dados geográficos da região de estudo com os dados de geomorfologia, hidrologia, declividade, malha urbana e rede viária. Em seguida, foram geradas representações na categoria MNT, onde os valores foram normalizados em intervalos [0,1] através da lógica booleana e fuzzy... (Resumo completo, clicar acesso eletrônico abaixo)

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In the eld of synthetical materials, often called in the literature as organic/molecular conductors or charge-transfer salts, the most prominient examples are the quasi onedimensional systems (TMTTF)2X and (TMTSF)2X, where TMTTF, TMTSF and X refers to tetrametiltetratiafuvaline, tetrametiltetraselenafuvaline and a monovalent anion (X = PF6

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The implementation of an Export and Processing Zone (ZEPs) brings several benefits to the local, state and federal economy, but often, only socioeconomic factors are considered, apart from several other factors that should be analyzed, such as the environment. In this context of industrialization and the struggle for sustainable development, this work propose to incorporate the environmental variable in the decision process for establishing industrial areas, in particular, the ZPE in the city of Fernandópolis, São Paulo state, Brazil, by examining several physical and environmental factors such as slope intervals, geological features, pedological factors and land use. Developed using a multicriteria analysis, a model has been elaborated, where these factors have received a proportional value according with their importance, supported by a GIS tool (Geographical Information System) and remote sensing products, such as images from CBERS satellite and SRTM radar, showing the suited areas for industrial activities, considering environmental conditions. This model may assist to take better decision about the ZPE implementation area and to reduce the negative environmental impacts that would result of poorly planned locations

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This study has as objective determining the chemical properties that serve as the basis for potential scientific and technological applications of seven species of fibrous plants cultivated in Brazil, which are: Banana” (Musa spp.), “Coco” (Cocos nucifera), Curauá (Ananas erectifolius), Fique (Furcraea andina), Piteira” (Furcraea gigantea), Sisal(Agave sisalana) and “Taboa” (Typha domingensis). The tests for determining the percent dry completely, extractives soluble in cold water, in hot water, in sodium hydroxide 1% and in ethanol-toluene, and the percentages of ash, hydrophobicity, lignin, holocellulose and cellulose were performed at the Department of Environmental Sciences, Agronomy College (FCA) of UNESP – Botucatu, São Paulo State. It also presents a literature review about these fibers and their potential applications. Differences between the results obtained and those found by other authors are possibly explained by variations on the origin of plant material, the harvest season, the climate and soil where they were grown. However, the results and the methodology used, serve as a basis for further studies with natural fibers

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O Brasil caracteriza-se pela pluralidade cultural e religiosa. Muitas religiões, como a Umbanda, o Candomblé e o Espiritismo, utilizam plantas em rituais ou com o intuito de combater doenças. No combate das doenças, as plantas medicinais são utilizadas com base no conhecimento tradicional, muitas vezes distorcido pela sociedade moderna. Portanto, há um risco inerente nesta prática, pois o efeito das plantas medicinais está relacionado à presença de substâncias químicas, geralmente metabólitos secundários, as quais exercem ação farmacológica de forma análoga aos fármacos sintéticos, bem como podem produzir reações adversas ou intoxicação. Além disso, o uso adequado das plantas medicinais envolve conhecimento sobre seu cultivo, colheita/coleta, modo de preparo, posologia e indicação. O objetivo deste trabalho foi realizar uma revisão bibliográfica sobre o uso de plantas medicinais por comunidades religiosas e avaliar o risco de sua utilização com base em evidências científicas. Concluiu-se no trabalho que a maioria das plantas utilizadas está de acordo, totalmente, ou em parte com as indicações de uso na medicina popular ou respaldadas por estudos científicos. Porém, algumas das plantas medicinais utilizadas apresentam alta toxicidade e a indicação de uso de algumas outras, não condiz com estudos científicos ou uso na medicina popular

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About eighty percent of the Brazilian municipalities have their residues in environmentally unsuitable sites and socially insalubrious. In this context, in the year 2010, instituted the National Policy on Solid Residues, which aims to integrated management and management environmentally appropriate of solid residues in Brazil (JUCA, 2002).The problem of urban residues is related to its origin and production in the same way that the concept of inexhaustibility and reflexes of compromising the environment, especially the pollution of soil, air and water resources (LIMA, 1995). Seeking a better residues management in the municipality of Apuí / AM and continuing work already started, Plan Solid Residues Management of the Apuí / AM, this work came to propose a better environmental compliance in relation to solid residues compared to 12305/2010 law that established deadlines / timelines on some actions such as landfills and the consequent elimination of environmentally sound disposal of residues by 2014 and thus began a study of potential areas for the implementation of the landfill were evaluated taking into consideration technical aspects (soil, vegetation, climate, hydrography, etc), legislation and Google Earth imagery. The result of the work over the 6 areas proposed by the City Hall was the choice of AREA 4 as the most indicated for the implementation of the landfill for the city of Apuí, which has 18,325 inhabitants (IBGE, 2011); some considerations were made if a new area can be proposed by the city to implement the landfill

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This paper describes the main steps in the study of Senna spectabilis, as part of our bioprospection studies, with the isolation of spectaline, cassine and other piperidine alkaloids, as well as the preparation of semi-synthetic analogues, and the studies of their pharmacological and toxicological properties, which led to the establishment of two candidate drugs for the treatment of Alzheimer disease.

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Pós-graduação em Agronomia (Ciência do Solo) - FCAV