Crecimiento económico, creación y erosión de empleo: un análisis intersectorial

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Tópicos sobre el modelo de insumo-producto: teoría y aplicaciones

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Um olhar sobre a toponímia dos rios em Mato Grosso do Sul

This study aims to analyze designative hydronyms – terms that name watercourses in general – within the hydronymy of Mato Grosso do Sul, available in the toponymic Atlas of the State of Mato Grosso do Sul database – ATEMS, which were extracted from the official maps of the IBGE, scale 1:100,000, related to the 78 cities in the state. Among these hydronyms, 149 toponyms relating to rivers were selected and analyzed according to their etymology, the taxonomic classification and morphosyntactic structure.

Treatment and complications of orbito-zygomatic fractures

The aim of the present study was to analyze the etiology, type and treatment employed in the orbito-zygomatic fractures (OZ). Also, postoperative complications are described and correlated with the type of treatment used. Fifty patients with OZ fractures were evaluated. Orbital fractures in which the zygomatic bone was not involved were excluded. Epidemiologic data and characteristics of treatment such as the type of material used for osteosynthesis, number of anatomical sites on which rigid internal fixation (RIF) was applied, surgical approaches and associated complications were recorded. The main causes of trauma were motorcycle and bicycle accidents, constituting 52% of the sample. The osteosynthesis system used was the 2.0 mm, except in four patients in whom the 1.5mm system was used for fixation at the infra-orbital rim. A total of 18% of the patients required reconstruction of the internal orbit and in all cases titanium mesh was used. 46% of the patients received RIF in three anatomical sites, most in the fronto-zygomatic suture, infra-orbital rim and zygomatic-maxillary buttress. The most frequent complication was paresthesia of the infra-orbital nerve (34 patients, 68%). Other findings were also discussed with the intent of better understanding the treatment of the OZ fractures.

Particularities in the technique of calvaria graft

Calvaria grafts provide good bone quantity for the reconstruction of the atrophic maxilla, and have lower morbidity and resorption rates when compared to iliac crest. The aim of this paper is to present the technique for obtaining a graft of the skull. Initially, the depth of the osteotomy is determined by a manually conducted bur, which establishes the limits of the structures of the skull (outer table, diploe and inner table), making the removal of bone blocks easier and safer. Thus, osteotomies of the blocks are made with greater security, avoiding the complications inherent to surgical technique. The case that will be presented it is from a male patient of 65 years who refused to submit to the iliac crest graft, opting for the calvaria, despite being bald, that is a contraindication for this treatment modality. A delicate suture associated with placement of titanium mesh to maintain the conformation of the patient's skull in the region of the bone defect, created after removal of the graft, provided a good cosmetic result at the donor site. The use of titanium mesh for re-anatomization of bone defects created in the grafts is well indicated for bald patients.

Study of the infrastructures and the fishing power in Gran Canaria

Máster en Gestión Sostenible de Recursos Pesqueros

La gobernanza del sector pesquero en Gran Canaria

[ES] El concepto de gobernanza del sector pesquero ha evolucionado notablemente a nivel mundial en los últimos años, conectando a instituciones económicas, administrativas, políticas y sociales, legitimando y equilibrando las interacciones entre todos los actores del sector, dentro de un marco de dimensión local, nacional e internacional. En este trabajo se describe el contexto en el que se inscribe la gobernanza del sector pesquero grancanario en la actualidad y los actores involucrados en dicha actividad, así como sus perfiles sociales, funciones e interacciones. Se analiza la gestión pesquera desde el punto de vista de la agilidad en sus funciones de cada una de las partes implicadas en la misma, en base al estudio de las competencias y cometidos otorgados por ley, el papel real ejercido por cada una y la percepción y concepción de las razones que conducen a la actual crisis del sector. La información analizada se obtuvo a partir de una revisión bibliográfica y la realización de entrevistas y encuestas a distintas personalidades relacionadas con la actividad pesquera. Se proponen medidas generales para promover un mejor funcionamiento organizativo del sector y fomentar su cohesión. Este trabajo proporciona una visión general de la gobernanza de la pesca en Gran Canaria, como punto de partida para la generación de políticas de gestión que integren la dinámica y la complejidad del sector a partir de un mejor conocimiento del mismo.

Paralelización de métodos de optimización de mallas 2D

Máster Universitario en Sistemas Inteligentes y Aplicaciones Numéricas en Ingeniería (SIANI)

Dispersión de materia orgánica en granjas de acuicultura : desarrollo de un modelo matemático para garantizar sus sostenibilidad ambiental

Proyecto MACAROMOD correspondiente al Programa de Cooperación Transnacional MAC, periodo 2007/2013, cofinanciado con fondos Feder;Jefe de fila: Universidad de Las Palmas de Gran Canaria. Socios del proyecto: Universidade das Açores (Portugal), Instituto Nacional das Pescas (Cabo Verde), Centro de Investigaciones Medioambientales del Atlántico S.L. (CIMA). Entidades colaboradoras: Fundación Universitaria de Las Palmas

Sobre la descripción visual automática del ser humano para aplicaciones de interacción hombre-máquina

Programa de doctorado: Sistemas Inteligente y Aplicaciones Numéricas en Ingeniería

Modelización de sólidos mediante estructura Octree

[EN]En este trabajo presentamos un procedimiento para la modelización de sólidos con geometríacompleja mediante una estructura octree [1]. Partiendo de una triangulación superficial del sólido, se construye una malla de hexaedros que aproxima la geometría con una precisión indicada. Para ello se emplea una división recursiva del espacio con una estructura octree. Inicialmente se lleva a cabo una traslación y escalado de la triangulación al cubo inicial [0,1]3 donde se construye el octree...

Uso de métodos ensemble para la predicción de la radiación solar

[EN]Se propone un modelo de radiación solar adaptativo como una nueva herramienta para la generación de mapas de radiación solar. Este introduce mejoras a los modelos existentes como la adaptación de la malla a la orografía y al albedo. Esta estrategia adaptativa nos permite generar un código eficiente que reduce el coste computacional para una precisión dada. La radiación global es obtenida como suma de sus tres componentes, la directa, la difusa y la reflejada, sobre una región de estudio bajo condiciones de cielo limpio. En este sentido, las superficies inclinadas tendrán un tratamiento diferente de las horizontales y se tendrá en cuenta el efecto de las zonas en sombra…

"Pseudo-Beijing": evidence for convergent evolution in the direct repeat region of Mycobacterium tuberculosis

Background Mycobacterium tuberculosis has a global population structure consisting of six main phylogenetic lineages associated with specific geographic regions and human populations. One particular M. tuberculosis genotype known as “Beijing” has repeatedly been associated with drug resistance and has been emerging in some parts of the world. “Beijing” strains are traditionally defined based on a characteristic spoligotyping pattern. We used three alternative genotyping techniques to revisit the phylogenetic classification of M. tuberculosis complex (MTBC) strains exhibiting the typical “Beijing” spoligotyping pattern. Methods and Findings MTBC strains were obtained from an ongoing molecular epidemiological study in Switzerland and Nepal. MTBC genotyping was performed based on SNPs, genomic deletions, and 24-loci MIRU-VNTR. We identified three MTBC strains from patients originating from Tibet, Portugal and Nepal which exhibited a spoligotyping patterns identical to the classical Beijing signature. However, based on three alternative molecular markers, these strains were assigned to Lineage 3 (also known as Delhi/CAS) rather than to Lineage 2 (also known as East-Asian lineage). Sequencing of the RD207 in one of these strains showed that the deletion responsible for this “Pseudo-Beijing” spoligotype was about 1,000 base pairs smaller than the usual deletion of RD207 in classical “Beijing” strains, which is consistent with an evolutionarily independent deletion event in the direct repeat (DR) region of MTBC. Conclusions We provide an example of convergent evolution in the DR locus of MTBC, and highlight the limitation of using spoligotypes for strain classification. Our results indicate that a proportion of “Beijing” strains may have been misclassified in the past. Markers that are more phylogenetically robust should be used when exploring strain-specific differences in experimental or clinical phenotypes.

First insights into the phylogenetic diversity of Mycobacterium tuberculosis in Nepal

Background Tuberculosis (TB) is a major public health problem in Nepal. Strain variation in Mycobacterium tuberculosis may influence the outcome of TB infection and disease. To date, the phylogenetic diversity of M. tuberculosis in Nepal is unknown. Methods and Findings We analyzed 261 M. tuberculosis isolates recovered from pulmonary TB patients recruited between August 2009 and August 2010 in Nepal. M. tuberculosis lineages were determined by single nucleotide polymorphisms (SNP) typing and spoligotyping. Drug resistance was determined by sequencing the hot spot regions of the relevant target genes. Overall, 164 (62.8%) TB patients were new, and 97 (37.2%) were previously treated. Any drug resistance was detected in 50 (19.2%) isolates, and 16 (6.1%) were multidrug-resistant. The most frequent M. tuberculosis lineage was Lineage 3 (CAS/Delhi) with 106 isolates (40.6%), followed by Lineage 2 (East-Asian lineage, includes Beijing genotype) with 84 isolates (32.2%), Lineage 4 (Euro-American lineage) with 41 (15.7%) isolates, and Lineage 1 (Indo-Oceanic lineage) with 30 isolates (11.5%). Based on spoligotyping, we found 45 different spoligotyping patterns that were previously described. The Beijing (83 isolates, 31.8%) and CAS spoligotype (52, 19.9%) were the dominant spoligotypes. A total of 36 (13.8%) isolates could not be assigned to any known spoligotyping pattern. Lineage 2 was associated with female sex (adjusted odds ratio [aOR] 2.58, 95% confidence interval [95% CI] 1.42–4.67, p = 0.002), and any drug resistance (aOR 2.79; 95% CI 1.43–5.45; p = 0.002). We found no evidence for an association of Lineage 2 with age or BCG vaccination status. Conclusions We found a large genetic diversity of M. tuberculosis in Nepal with representation of all four major lineages. Lineages 3 and 2 were dominating. Lineage 2 was associated with clinical characteristics. This study fills an important gap on the map of the M. tuberculosis genetic diversity in the Asian region.

Two new rapid SNP-typing methods for classifying Mycobacterium tuberculosis complex into the main phylogenetic lineages

There is increasing evidence that strain variation in Mycobacterium tuberculosis complex (MTBC) might influence the outcome of tuberculosis infection and disease. To assess genotype-phenotype associations, phylogenetically robust molecular markers and appropriate genotyping tools are required. Most current genotyping methods for MTBC are based on mobile or repetitive DNA elements. Because these elements are prone to convergent evolution, the corresponding genotyping techniques are suboptimal for phylogenetic studies and strain classification. By contrast, single nucleotide polymorphisms (SNP) are ideal markers for classifying MTBC into phylogenetic lineages, as they exhibit very low degrees of homoplasy. In this study, we developed two complementary SNP-based genotyping methods to classify strains into the six main human-associated lineages of MTBC, the "Beijing" sublineage, and the clade comprising Mycobacterium bovis and Mycobacterium caprae. Phylogenetically informative SNPs were obtained from 22 MTBC whole-genome sequences. The first assay, referred to as MOL-PCR, is a ligation-dependent PCR with signal detection by fluorescent microspheres and a Luminex flow cytometer, which simultaneously interrogates eight SNPs. The second assay is based on six individual TaqMan real-time PCR assays for singleplex SNP-typing. We compared MOL-PCR and TaqMan results in two panels of clinical MTBC isolates. Both methods agreed fully when assigning 36 well-characterized strains into the main phylogenetic lineages. The sensitivity in allele-calling was 98.6% and 98.8% for MOL-PCR and TaqMan, respectively. Typing of an additional panel of 78 unknown clinical isolates revealed 99.2% and 100% sensitivity in allele-calling, respectively, and 100% agreement in lineage assignment between both methods. While MOL-PCR and TaqMan are both highly sensitive and specific, MOL-PCR is ideal for classification of isolates with no previous information, whereas TaqMan is faster for confirmation. Furthermore, both methods are rapid, flexible and comparably inexpensive.