Prognostic value of microvascular invasion in predicting the cancer specific survival and risk of metastatic disease in renal cell carcinoma: a multicenter investigation

While microvascular invasion is an accepted risk factor in various cancers, its prognostic role in renal cell carcinoma is still unclear. Therefore, a large multicenter study examining the experience of 5 international institutions was performed to evaluate the prognostic value of microvascular invasion in the occurrence of metastases and cancer specific survival.

Role of Crop Research and Development in food Security of Africa

Food security is the main concern in Africa as the production and productivity of crops are under continuous threat. Indigenous crops also known as orphan- or as underutilized- crops provide key contributions to food security under the present scenario of increasing world population and changing climate. Hence, these crops which belong to the major categories of cereals, legumes, fruits and root crops play a key role in the livelihood of the resource-poor farmers and consumers since they perform better than the major world crops under extreme soil and climate conditions prevalent in the continent. These indigenous crops have the major advantage that they fit well into the general socio-economic and ecological context of the region. However, despite their huge importance, African crops have generally received little attention by the global scientific community. With the current production systems, only a fraction of yield potential was achieved for most of these crops. In order to devise strategies towards boosting crop productivity in Africa, the current production constraints should be investigated and properly addressed. Key traits known to increase productivity and/or improve nutrition and diverse conventional and modern crop improvement techniques need to be implemented. Commitments in the value-chain from the research, production, marketing to distribution of improved seeds are required by relevant national and international institutions as well as African governments to promote food security in a sustainable manner. The review also presents major achievements and suggestions for stakeholders interested in African agriculture.

Sustainable investment in land in the Global South: What would it require from a coherence perspective? The case of Sierra Leone

Large scale acquisitions of land in the Global South have signifi-cantly increased since the millennium. It is often the case that foreign investors are involved in such acquisitions, which are commonly aimed at facilitating the export of commodities. These investments in land tend to transform conventional, rather small scale agricultural systems into large scale, industrial agricultural systems. While investment in ag-riculture in the Global South is much needed, large-scale investments in land often goes hand-in-hand with environmental and human rights re-lated challenges. As a consequence, lawyers need to address questions of sovereignty over natural resources (this paper focuses in particular on land resources), to peoples’ right to self-determination, to the responsi-bilities of the home and host states of the investors, including public-private relationships, and the role of international institutions who are involved, as well as relevant jurisprudence. This paper approaches these questions from the perspective of a theory on policy coherence for sus-tainable development.

WOCAT - World Overview of Conservation Approaches and Technologies - Preliminary results from Eastern and Southern Africa

The World Overview of Conservation Approaches and Technologies (WOCAT) is a program of the World Association of Soil and Water Conservation (WASWC), organized as a consortium of several international institutions. The overall goal of WOCAT is to contribute to sustainable utilization of soil and water. WOCAT collects and analyzes information on soil and water conservation (SWC) technologies and approaches world-wide, and presents the collected information in computer databases and decision support systems, and in the form of handbooks, reports and maps readily accessible to SWC specialists and policy-makers world-wide. WOCAT has prepared a framework for the evaluation of soil and water conservation and has started data collection. The paper presents preliminary results with promising SWC technologies and approaches used in Eastern and Southern Africa. The first finding is that hardly any promising SWC activities could be found on common grazing lands. Analysis of the cropland shows some of the bio-physical and socioeconomic conditions under which certain SWC technologies and approaches are used, including land use types, climatic zones and land tenure, and looks at issues such as participation and costs. Furthermore, classification criteria for SWC technologies and approaches are discussed.

Estimación del riesgo sísmico en puerto príncipe (Haití)

Tras el devastador terremoto del 12 de enero de 2010 en Puerto Príncipe, Haití, las autoridades locales, numerosas ONGs y organismos nacionales e internacionales están trabajando en el desarrollo de estrategias para minimizar el elevado riesgo sísmico existente en el país. Para ello es necesario, en primer lugar, estimar dicho riesgo asociado a eventuales terremotos futuros que puedan producirse, evaluando el grado de pérdidas que podrían generar, para dimensionar la catástrofe y actuar en consecuencia, tanto en lo referente a medidas preventivas como a adopción de planes de emergencia. En ese sentido, este Trabajo Fin de Master aporta un análisis detallado del riesgo sísmico asociado a un futuro terremoto que podría producirse con probabilidad razonable, causando importantes daños en Puerto Príncipe. Se propone para ello una metodología de cálculo del riesgo adaptada a los condicionantes de la zona, con modelos calibrados empleando datos del sismo de 2010. Se ha desarrollado en el marco del proyecto de cooperación Sismo-Haití, financiado por la Universidad Politécnica de Madrid, que comenzó diez meses después del terremoto de 2010 como respuesta a una petición de ayuda del gobierno haitiano. El cálculo del riesgo requiere la consideración de dos inputs: la amenaza sísmica o movimiento esperado por el escenario definido (sismo de cierta magnitud y localización) y los elementos expuestos a esta amenaza (una clasificación del parque inmobiliario en diferentes tipologías constructivas, así como su vulnerabilidad). La vulnerabilidad de estas tipologías se describe por medio de funciones de daño: espectros de capacidad, que representan su comportamiento ante las fuerzas horizontales motivadas por los sismos, y curvas de fragilidad, que representan la probabilidad de que las estructuras sufran daños al alcanzar el máximo desplazamiento horizontal entre plantas debido a la mencionada fuerza horizontal. La metodología que se propone especifica determinadas pautas y criterios para estimar el movimiento, asignar la vulnerabilidad y evaluar el daño, cubriendo los tres estados del proceso. Por una parte, se consideran diferentes modelos de movimiento fuerte incluyendo el efecto local, y se identifican los que mejor ajustan a las observaciones de 2010. Por otra se clasifica el parque inmobiliario en diferentes tipologías constructivas, en base a la información extraída en una campaña de campo y utilizando además una base de datos aportada por el Ministerio de Obras Públicas de Haití. Ésta contiene información relevante de todos los edificios de la ciudad, resultando un total de 6 tipologías. Finalmente, para la estimación del daño se aplica el método capacidad-demanda implementado en el programa SELENA (Molina et al., 2010). En primer lugar, utilizado los datos de daño del terremoto de 2010, se ha calibrado el modelo propuesto de cálculo de riesgo sísmico: cuatro modelos de movimiento fuerte, tres modelos de tipo de suelo y un conjunto de funciones de daño. Finalmente, con el modelo calibrado, se ha simulado un escenario sísmico determinista correspondiente a un posible terremoto con epicentro próximo a Puerto Príncipe. Los resultados muestran que los daños estructurales serán considerables y podrán llevar a pérdidas económicas y humanas que causen un gran impacto en el país, lo que pone de manifiesto la alta vulnerabilidad estructural existente. Este resultado será facilitado a las autoridades locales, constituyendo una base sólida para toma de decisiones y adopción de políticas de prevención y mitigación del riesgo. Se recomienda dirigir esfuerzos hacia la reducción de la vulnerabilidad estructural - mediante refuerzo de edificios vulnerables y adopción de una normativa sismorresistente- y hacia el desarrollo de planes de emergencia. Abstract After the devastating 12 January 2010 earthquake that hit the city of Port-au-Prince, Haiti, strategies to minimize the high seismic risk are being developed by local authorities, NGOs, and national and international institutions. Two important tasks to reach this objective are, on the one hand, the evaluation of the seismic risk associated to possible future earthquakes in order to know the dimensions of the catastrophe; on the other hand, the design of preventive measures and emergency plans to minimize the consequences of such events. In this sense, this Master Thesis provides a detailed estimation of the damage that a possible future earthquake will cause in Port-au-Prince. A methodology to calculate the seismic risk is proposed, adapted to the study area conditions. This methodology has been calibrated using data from the 2010 earthquake. It has been conducted in the frame of the Sismo-Haiti cooperative project, supported by the Technical University of Madrid, which started ten months after the 2010 earthquake as an answer to an aid call of the Haitian government. The seismic risk calculation requires two inputs: the seismic hazard (expected ground motion due to a scenario earthquake given by magnitude and location) and the elements exposed to the hazard (classification of the building stock into building typologies, as well as their vulnerability). This vulnerability is described through the damage functions: capacity curves, which represent the structure performance against the horizontal forces caused by the seisms; and fragility curves, which represent the probability of damage as the structure reaches the maximum spectral displacement due to the horizontal force. The proposed methodology specifies certain guidelines and criteria to estimate the ground motion, assign the vulnerability, and evaluate the damage, covering the whole process. Firstly, different ground motion prediction equations including the local effect are considered, and the ones that have the best correlation with the observations of the 2010 earthquake, are identified. Secondly, the classification of building typologies is made by using the information collected during a field campaign, as well as a data base provided by the Ministry of Public Works of Haiti. This data base contains relevant information about all the buildings in the city, leading to a total of 6 different typologies. Finally, the damage is estimated using the capacity-spectrum method as implemented in the software SELENA (Molina et al., 2010). Data about the damage caused by the 2010 earthquake have been used to calibrate the proposed calculation model: different choices of ground motion relationships, soil models, and damage functions. Then, with the calibrated model, a deterministic scenario corresponding to an epicenter close to Port-au-Prince has been simulated. The results show high structural damage, and therefore, they point out the high structural vulnerability in the city. Besides, the economic and human losses associated to the damage would cause a great impact in the country. This result will be provided to the Haitian Government, constituting a scientific base for decision making and for the adoption of measures to prevent and mitigate the seismic risk. It is highly recommended to drive efforts towards the quality control of the new buildings -through reinforcement and construction according to a seismic code- and the development of emergency planning.

Terasense WP03 radiation and sensor measurement lab workpackage

This paper explains the progress accomplished in the WP03 of the Terasense Project (TERAHERTZ TECHNOLOGY FOR ELECTROMAGNETIC SENSING APPLICATIONS) approved in the 2008 CONSOLIDERINGENIO program (project CSD2008-0068). The Radiation and Sensor Measurement Lab (RSMLab) is a laboratory based in the existing antenna measurement laboratories at UPM, UC3 and UNiOvi and the new capacities to extend the measurement range from the millimetre wave to the THz region. This laboratory is intended to be shared in more than one place and with more than one institution, in such a way that we could take advantage of other research financial sources and contributions from other institutions with interest in the same field of measurements. One important task will be the international links between the RSMLab and other European and international institutions dedicated to the antenna and sensor measurement in the same frequency range.

Anatomía comparada de la madera de Cupressaceae y su correspondencia con los estudios de filogenia

La familia Cupressaceae incluye un total de 133 especies agrupadas en 30 géneros, 17 de los cuales son monospecíficos. Esta familia se encuentra representada en todos los continentes salvo en la Antártida. Sus especies se distribuyen en distintas regiones climáticas, y en altitudes que varían desde el nivel del mar hasta los 5.000 m. La falta de descripción anatómica de muchos de los géneros y especies de Cupressaceae es notable, así como la contradicción que aparece entre distintas investigaciones sobre las características anatómicas de la madera descritas para cada especie. Este estudio describe la anatomía de la madera de Cupressaceae y analiza las características que podrían representar sinapomorfías de los clados delimitados en los estudios filogenéticos. Siguiendo los métodos tradicionales de preparación y descripción de la madera a nivel microscópico, se ha estudiado la madera de 113 especies de los 30 géneros de Cupressaceae. Para ello se han empleado muestras de madera de origen trazable, procedentes de colecciones de madera de distintas instituciones internacionales. Se ha empleado una robusta filogenia molecular para la reconstrucción de los caracteres ancestrales. La anatomía de la madera de los 30 géneros de Cupressaceae, pone de manifiesto la gran homogeneidad de la familia, caracterizada por la presencia de traqueidas axiales sin engrosamientos helicoidales, parénquima radial con paredes horizontales lisas, punteaduras del campo de cruce de tipo cupresoide y la carencia de canales resiníferos fisiológicos. Además, todos presentan parénquima axial (salvo Neocallitropsis, Thuja y Xanthocyparis), punteaduras radiales areoladas con toro definido (salvo Thuja y Thujopsis), siendo habitual la presencia de punteaduras areoladas en las paredes tangenciales de la madera tardía, y verrugosidades en la cara interna de las traqueidas (salvo Ca. macleayana, Libocedrus, Papuacedrus y Neocallitropsis). Los radios leñosos son homogéneos y están compuestos de parénquima radial (con la presencia de traqueidas radiales en algunas especies de Cupressus, Sequoia, Thujopsis y X. nootkatensis) con paredes finales lisas o lisas y noduladas (exclusivamente noduladas en Cal. macrolepis, C. bakeri y en la mayoría de especies de Juniperus), y el rango de altura de los radios leñosos se encuentra entre 5 y 15 células. Se consideran posibles sinapomorfismos de Cupressaceae la presencia de verrugosidades en la cara interna de las traqueidas, la presencia de traqueidas axiales sin engrosamientos helicoidales, la presencia de parénquima axial, la presencia de radios leñosos homogéneos (compuestos únicamente de parénquima radial), la tipología de las paredes horizontales del parénquima radial, las punteaduras del campo de cruce de tipo cupresoide y la ausencia de canales resiníferos fisiológicos, pero lo que realmente diferencia a este grupo de coníferas es la simultaneidad de todos estos caracteres en sus maderas. Como sinapomorfías específicas por clados se proponen: la ausencia de toro definido y muescas en el borde de las punteaduras en Thuja-Thujopsis, la existencia de extensiones de toro en Diselma-Fitzroya-Widdringtonia; la presencia de engrosamientos callitroides en Callitris-Actinostrobus; la presencia de espacios intercelulares y las muescas en el borde de las punteaduras en el clado formado por el género Juniperus y las especies de Cupressus en la región oriental; la presencia de paredes finales del parénquima radial tanto lisas como noduladas en los clados formados por el género Xanthocyparis y las especies de Cupressus en la región occidental y en Fitzroya-Diselma; y por último, la presencia de punteaduras del campo de cruce de tipo taxodioide en los clados taxodioid y sequoioid. ABSTRACT The Cupressaceae family comprises 133 species grouped into 30 genera, 17 of which are monotypic. The family is represented in all continents except Antarctica. Its species are distributed in various climate zones and at altitudes from sea level to 5,000 m. There is a considerable lack of anatomical descriptions for many genera and species of Cupressaceae and much contradiction between studies about the wood anatomical features described for each species. This study describes the wood anatomy of Cupressaceae and analyses the features that could represent synapomorphies of the clades recovered in phylogenetic studies. Following the traditional methods of preparation and description of wood at microscopic level, a study was made of the wood of 113 species of the 30 Cupressaceae genera. The study samples had traceable origins and came from wood collections held at various international institutions. A robust molecular phylogeny was used for ancestral state reconstruction. The wood anatomy of the 30 genera of the Cupressaceae shows the high homogeneity of the family, which is characterised by the presence of axial tracheids without helical thickenings, smooth horizontal walls of ray parenchyma cells, cupressoid cross-field pits, and the absence of physiological resin canals. In addition, they all have axial parenchyma (except Neocallitropsis, Thuja and Xanthocyparis), a warty layer on the inner wall of the tracheids (except Ca. macleayana, Libocedrus, Papuacedrus and Neocallitropsis) and tracheid pitting in radial walls with a well defined torus (except Thuja and Thujopsis); tracheid pitting in the tangential walls of the latewood is common. Rays are homogeneous and are composed of ray parenchyma (with the presence of ray tracheids in some species of Cupressus, Sequoia, Thujopsis and X. nootkatensis), with smooth end walls or both smooth and nodular end walls (exclusively nodular in Cal. macrolepis, C. bakeri and most Juniperus species), and ray height range is 5 to 15 cells. Possible synapomorphies of Cupressaceae are the presence of a warty layer on the inner layer of the tracheids, axial tracheids without helical thickenings, the presence of axial parenchyma, homogeneous rays (composed exclusively of ray parenchyma), the typology of the horizontal walls of ray parenchyma cells, cupressoid cross-field pits and the absence of physiological resin canals, but what truly differentiates this group of softwoods is the co-occurrence of all these features in their wood. The following are proposed as clade-specific synapomorphies: absence of a well-defined torus and presence of pits with notched borders in Thuja-Thujopsis, torus extensions in Diselma-Fitzroya-Widdringtonia; callitroid thickenings in Callitris-Actinostrobus; intercellular spaces and pits with notched borders in the clade formed by the genus Juniperus and the species of Cupressus in the eastern region; smooth and nodular ray parenchyma end walls in the clades formed by the genus Xanthocyparis and the species of Cupressus in the western region and in Fitzroya-Diselma, and taxodioid cross-field pits in the taxodioid and sequoioid clades.

A first approach to earthquake damage estimation in Haiti: advices to minimize the seismic risk

This study is in the frame of the cooperative line that several Spanish Universities and other foreign partners started with the Haitian government in 2010. According to our studies (Benito et al. in An evaluation of seismic hazard in La Hispaniola, after the 2010 Haiti earthquake, 33rd General Assembly of the European Seismological Commission, Moscow, Russia, 2012) and recent scientific literature, the earthquake hazard in Haiti remains high (Calais et al. in Nat Geosci 3:794–799, 2010). In view of this, we wonder whether the country is currently ready to face another earthquake. In this sense, we estimated several damage scenarios in Port-au-Prince and Cap-Haitien associated to realistic possible major earthquakes. Our findings show that almost 50 % of the building stock of both cities would result uninhabitable due to structural damage. Around 80 % of the buildings in both cities have reinforced concrete structure with concrete block infill; however, the presence of masonry buildings becomes significant (between 25 and 45 % of the reinforced concrete buildings) in rural areas and informal settlements on the outskirts, where the estimated damage is higher. The influence of the soil effect on the damage spatial distribution is evident in both cities. We have found that the percentage of uninhabitable buildings in soft soil areas may be double the percentage obtained in nearby districts located in hard soil. These results reveal that a new seismic catastrophe of similar or even greater consequences than the 2010 Haiti earthquake might happen if the earthquake resilience is not improved in the country. Nowadays, the design of prevention actions and mitigation policies is the best instrument the society has to face seismic risk. In this sense, the results of this research might contribute to define measures oriented to earthquake risk reduction in Haiti, which should be a real priority for national and international institutions.

A tale of oversimplification and deregulation: the mainstream approach to labour market segmentation and the recent responses to the crisis in European countries. WP C.S.D.L.E. “Massimo D’Antona”.INT – 102/2013

After advocating flexibilization of non-standard work contracts for many years, some European and international institutions and several policy makers now indicate the standard employment relationship and its regulation as a cause of segmentation between the labour market of "guaranteed" insiders, employed under permanent contracts with effective protection against unfair dismissal, and the market of the “not-guaranteed” outsiders, working with non-standard contracts. Reforms of employment legislation are therefore being promoted and approved in different countries, allegedly aiming to balance the legal protection afforded to standard and non-standard workers. This article firstly argues that this approach is flawed as it oversimplifies reasons of segmentation as it concentrates on an “insiders-outsiders” discourse that cannot easily be transplanted in continental Europe. After reviewing current legislative changes in Italy, Spain and Portugal, it is then argued that lawmakers are focused on “deregulation” rather than “balancing protection” when approving recent reforms. Finally, the mainstream approach to segmentation and some of its derivative proposals, such as calls to introduce a “single permanent contract”, are called into question, as they seem to neglect the essential role of job protection in underpinning the effectiveness of fundamental and constitutional rights at the workplace.

Global Solutions, Local Damages: A Critical Study in Judicial Councils in Central and Eastern Europe. Research Paper in Law 07/2013

This article examines why, how, and with what results have judicial councils spread under the influence of European institutions throughout Central and Eastern Europe in the course of the last twenty years. It first traces back how the judicial councils, themselves just one possible form of administration of courts, have emerged as the recommended universal solution Europe-wide and internationally. Second, it discusses how has this model been exported under the patronage of European and international institutions to transition countries in Central and Eastern Europe. Assessing, thirdly, the reality of the functioning of such new judicial councils in these countries, in particular in Slovakia and Hungary, with the Czech Republic without a judicial council providing a counter-example, it is suggested that their impact on further judicial and legal transition has been either questionable or outright disastrous. This brings, eventually, into question the legitimacy as well as the bare reasonableness of the entire process of European/international standards setting and their later marketing or in reality rather imposition onto the countries in transition.

Reform momentum and its impact on Greek growth. Bruegel Policy Contribution 2015/12, July 2015

Greece has an imperfect track-record of structural reform implementation. However, the poor growth outcome of the Greek programmes is also a consequence of the timing and composition of reforms, which were not optimally geared towards a speedy transition to a new growth model based on the private sector. While the main responsibility for this lies with the Greek authorities, international institutions share the responsibility for the poor growth-enhancing effect of reforms. In the current context, further structural reform efforts should be mainly targeted at supporting Greece's speedy return to solid growth rates. This is not only because poverty and unemployment have reached very high levels, but also for political economy reasons: reforms must quickly be seen to be working in order to buttress the consensus in favour of reform. Further efforts should be made to improve Greece’s business environment and to liberalise product markets, in addition to shifting taxation away from labour and towards consumption. Reforms to improve the quality of institutions should continue and are very much needed in the Greek setting, while taking into account that their demanding implementation might use up administrative capacity and their impact on growth will only be seen over long time horizons.

Introduction to organisational behaviour

Introduction to Organisational Behaviour is the first truly integrated multimedia package for introductory OB modules. It provides a rigorous critique of the essential organisational behaviour topics in a creative, interactive and visual way. Key features include: - Practitioner case studies presenting real organisational dilemmas accompanied by video interviews online where the practitioners talk about approaches and solutions - Tailored tutor resources online, recognising that you have different needs - one area is designed for new OB lecturers; the other contains materials for more experienced OB lecturers - An underpinning focus on employability skills, with tips in the book on how each topic could be linked to different skills and professionally produced video demonstrations online - A global perspective reflecting today's market-place, integrated through global examples and theories including those from developing countries - Innovative learning features including ethical dilemmas, best and worst practice examples, taking your learning further, review and discussion questions, applying theory to practice and a glossary - Written by a team of experts at prestigious UK-based and international institutions - A foreword by Richard Atfield of the Higher Education Academy. Online resources For tutors: - Interviews with practitioners - Demonstrations of employability skills - Additional short and long case study per chapter with questions - Additional discussion and assignment questions - Tutorial activities - PowerPoint slides - Guidance notes - Figures and tables from the book For students: - Web links including YouTube links and links to seminal articles

Heterodox gazdaságpolitikák korszaka? (An Age of Heterodox Economic Policies?)

A világ fejlett pénzügyi piacainak válságát követően önvizsgálatra kényszerült a közgazdaságtudomány, amelyet nemcsak az alternatív és heterodox irányzatok képviselői, a média és a nagyközönség, hanem a gazdasági döntéshozók részéről is erős kritikák értek. Egyidejűleg gyors változásokon ment át a gazdaságpolitikai gyakorlat, különösen a válság által erősen érintett országokban, megszaporodtak a korábbi mérvadó kormányzati gyakorlat (best practice) ajánlásaitól távol álló, nem szokványos megoldások, heterodox politikák. Az esszé szerzője meghatározó személyiségek véleményének, vezető intézmények álláspontjának és kormányzati gazdaságpolitikáknak az áttekintése alapján egyfelől azt a kérdést vizsgálja, hogy körvonalazódik-e új gazdaságelméleti irányzat, amely doktrinális alapul szolgálhatna a gazdaságpolitikai döntéshozatalhoz, másodsorban pedig: átmeneti jelenség-e az egymástól alapvetően különböző felfogású, logikájú gazdaságpolitikák egyidejű megléte, avagy várható-e egy új konszenzus kialakulása. ______ In the wake of the recent financial turmoil emanating from top financial centers, the economic profession has been forced to conduct introspection due to harsh criticism from alternative and heterodox economists, the media, and the general public as well as from decision makers. Meanwhile, the economic policy making practice has profoundly changed, particularly in countries heavily affected in the crisis; decision makers increasingly apply non customary (heterodox) measures in defiance of former best practice of economic policy making. The author of this essay, having investigated the related views of leading economists and influential international institutions and having reviewed economic policy making practice, raises two questions. One: is there a new economic theory evolving that will provide doctrinal underpinning to post crisis economic policy making? Second: is the simultaneity of widely differing economic policy practices and policy orientations a transitional phenomenon, or are there signs of a new policy consensus emerging? It may be too early to give argued answers to the questions, but the present – rather technical – economic theory mainstream seems to maintain its central position, yet is becomes more open to research topics and methods acknowledging the complexity of economic processes and social institutions, and to impulses emanating from economic practice. As for economic policy making is concerned, continuous decline of the economic importance of leading Western nations prolongs the period of heterogeneity of non conventional, heterodox policies both in advanced and in emerging countries until new policy norms, a “new normal” emerges.

Teoretycznoprawne aspekty operacjonalizacji ochrony praw człowieka w państwie z perspektywy globalnego systemu prawa (Zarys problematyki)

The article is devoted to the presentation of the outline of the concept of operationalization of human rights taking place in the states involved in the system of international protection of those rights. The concept of operationalization of protection is a collective term for a series of processes that lead to the establishment of legal provisions protecting human rights, and to transfer this abstract construct to specific societies. It includes both the decision-making processes of extralegal (uprising idea, its conceptualization, social issues and change the perception of axiology of society, cultural aspects) and legal (lawmaking and law application processes in the aspect of human rights and the impact of international institutions on them) character. The essence of the process of operationalization is providing effective protection of human rights in a state. The concept is set primarily on the consequences of membership of Poland in the system of the Council of Europe.

Connecting people and ideas from around the world: global innovation platforms for next-generation ecology and beyond

We present a case for using Global Community Innovation Platforms (GCIPs), an approach to improve innovation and knowledge exchange in international scientific communities through a common and open online infrastructure. We highlight the value of GCIPs by focusing on recent efforts targeting the ecological sciences, where GCIPs are of high relevance given the urgent need for interdisciplinary, geographical, and cross-sector collaboration to cope with growing challenges to the environment as well as the scientific community itself. Amidst the emergence of new international institutions, organizations, and meetings, GCIPs provide a stable international infrastructure for rapid and long-term coordination that can be accessed by any individual. This accessibility can be especially important for researchers early in their careers. Recent examples of early-career GCIPs complement an array of existing options for early-career scientists to improve skill sets, increase academic and social impact, and broaden career opportunities. We provide a number of examples of existing early-career initiatives that incorporate elements from the GCIPs approach, and highlight an in-depth case study from the ecological sciences: the International Network of Next-Generation Ecologists (INNGE), initiated in 2010 with support from the International Association for Ecology and 20 member institutions from six continents.