Efeito da exposição à fumaça de cigarro durante a prenhez e a lactação de ratas e sua prole sobre parâmetros séricos e morfométricos

PURPOSE: to investigate the effect of cigarette smoke exposure on body and tissue weight gain, serum parameters and milk yield during pregnancy and lactation in rats, and the impact on offspring from birth toil young adulthood. METHODS: 40 Wistar pregnant rats were randomly divided into: CG - not exposed to cigarette smoke and sacrificed at the end of pregnancy; CL - not exposed to cigarette smoke and sacrificed at the end of lactation; FG - exposed to cigarette smoke and sacrificed at the end of pregnancy; FL - exposed to cigarette smoke and sacrificed at the end of lactation. The offspring were separated by gender and divided according to their mothers' groups. Tissue weight, body weight and serum parameters were evaluated in rats and offspring. Milk yield per pup was calculated. RESULTS: body weight was decreased in FL during lactation (CL=267.0±7.2; FL=235.5±7.2 g*, *p<0.05). Adipose tissue was not detected in the CL and FL groups, and was reduced in FG compared to CG (CG=3.3±0.3; FG=2.4±0.3 g*, *p<0.05). Rats exposed to cigarette smoke had higher blood glucose levels (CG=113±17, CL=86±16, FG=177±21*, FL=178±23 mg/dL*, *p<0.05 CG versus FG e CL versus FL), CL and FL groups presented lower HDL-cholesterol with no change in total cholesterol. Finally, rats exposed to cigarette smoke had lower milk yield compared to unexposed rats (CL=6.7±0.4, FL=5.4±0.3 g*, *p<0.05). In offspring from the FG and FL groups, there was a decrease of body weight from birth to young adulthood, with no changes in gastrocnemius, liver or heart weights in any group, and adipose tissue was no detected in female offspring. There was an increase in blood glucose in offspring of both sexes from rats exposed to cigarette smoke (males: Pcg=107±10.5, Pcl=115±8.6, Pfg=148±16.8*, Pfl=172±11.2**; females: Pcg=109±27.2, Pcl=104±9.7, Pfg=134±20.0*, Pfl=126±13.3**; p<0.05 *Pcg versus Pfg and **Pcl versus Pfl). CONCLUSIONS: exposure to cigarette smoke provokes impairment of morphometric and serum parameters during pregnancy and lactation both in mothers and offspring, which is maintained during young adulthood.

Intervenções em linguagem escrita: Uma revisão da literatura com vistas à redução dos transtornos funcionais de aprendizagem

The importance reading and writing and being able to use these skills in a variety of situations is an absolute reality. In our society in which reading and writing are widely used, Brazil still faces severe problems with literacy, as revealed in literacy statistics and in the large number of students with learning disabilities. Thus, our text aims to present a survey of the research that focuses on intervention programs highlighting the needs of this group, with special attention on the use of narrative or storytelling. Specific criteria were established, the main one being the period of the publications (2000 to 2010). The results of the analysis of 15 texts showed that intervention is the most neglected area. International literature presents concerns related to scientific rigor or greater control of variables related to ongoing programs, as well as measures for generalizing the effective use of these programs, within verbal communities, with special focus on schools. Our revision enabled us to conclude that, even though production on written language is large, international literature is much more expressive with reference to intervention programs. Furthermore, in both national and international literature, production concerning the understanding of written language processes of acquisition and development prevails.

Substituição dos grãos secos de milho pela silagem de grãos úmidos de milho para vacas da raça holandesa em lactação

In order to evaluate the effects of replacement of dried corn (GSM) for silage moisture corn (HMCS) on production and milk composition were used five Holstein cows, primiparous with a mean of 112 days post delivery, confined in Tie Stall, for 70 days. We used five diets according to NRC to 17.5% CP (DM) and 2.4 Mcal / kg DM, the 40:60 ratio of roughage and concentrate containing soybean meal, sugar cane silage and hay and substitution levels of the GSM HMCS the following treatments: a) 0%, 2) 25%, 3) 50%, 4) 75% and 5) 100%. Milk production and dry matter intake (DMI) were recorded daily. The animals were milked daily 6:00 and 18:00 h, and milk samples collected from consecutive milkings of each experimental period of 14 days (four days of collection). The experimental design was a 5x5 Latin square and the data analyzed by the statistical program SAS. Body weight (508 kg), milk (23.6 kg), corrected milk (22.7 kg), DMI (17.13 kg) showed no significant difference, but the intakes of neutral detergent fiber (6.67 kg), and detergent acid (3.39 kg), feed efficiency for the production of milk (milk 1.41 kg / day) urea nitrogen (17.67 mg / dL) differ, thus indicating that HMCS is more efficient than GSM in the diet of dairy cows not alter the production and milk composition.

Proteinograma do soro lácteo de ovelhas da raça santa inês em diferentes fases de lactação

This study aimed to evaluate the influence of lactation phases on the proteinogram of whey protein in Santa Inês ewes. Ewes were accompanied in a semi-intensive system using the same sanitary and nutritional management evaluated at 15, 30, 60 and 90 days postpartum (end of weaning and lactation). Clinical examination of the mammary gland was carried out through and bacteriological culture. The screening of the material resulted in 44 milk samples of healthy glands concurrent negative by CMT and bacteriological culture exam. For obtaining the whey protein renin solution was used. The whey was fractionated into aliquots and kept in the -80C freezer to later separation of protein fractions. For determination of total protein of whey protein was employed the biuret, observing the linearity of the test. Separation of protein fractions was performed, using polyacrylamide gel containing sodium dodecyl sulfate (SDS-PAGE). Eigth protein were observed including lactoferrin, serum albumin, IgA, IgG (heavy chain IgG (IgG CP), light chain IgG (IgG CL), ß-lactoglobulin, a-lactalbumin and proteins identified as PM 15000 and PM 29000. No significant difference was observed at different stages of lactation in the following protein: IgA (P>0.3895), lactoferrin (P>0.1611), PM 29000 (P>0.4879), α-lactalbumin (P>0.0799) and PM15000 (P>0.4494). In total protein (P<0.0022), albumin protein (P<0.0377) and IgG (P<0.0354) it was observed a significant variation in the first moments of observations, in the ß-lactoglobulin protein (P<0.0005) there was significant variation with reduction of 15 to 30 days postpartum with progressive elevation until the last stage of lactation (90 days postpartum). The SDS-PAGE technique allowed the quantification of eigth whey proteins in health ewes. The protein fractions identified reflect the profile of whey to ovine species, with influence of stages of lactation in albumin, IgG and ß-lactoglobulin.

Identificação precoce do risco para transtornos da atenção e da leitura em sala de aula

In this his study the accuracy was investigated of collective pedagogical activities, based on phonological judgments by matching figures and figures to spoken words, to identify students at risk for reading and/or attention disorders. Forty-five second graders (mean age of 7 years, 29 males) were divided into two groups, a control group, without reading difficulties (n=32), and an at-risk group, with reading difficulties (n=13). The low-achievement on these collective activities, defined by scores more than 1.65 SD below the mean of the control group, presented good sensitivity (true positives) and specificity (true negatives) in the early identification of at risk students.

Efeitos do tabagismo passivo associado ao exercício físico durante prenhez e lactação

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

A preparação e a execução de tarefa de alcance ao alvo em crianças com transtornos do desenvolvimento da coordenação

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Desenvolvimento sexual da prole de ratas submetidas à restrição proteica em diferentes períodos da prenhez e lactação

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Da loucura à ciência: as imagens e a construção das notícias sobre os transtornos mentais e de comportamentos e seus personagens na Folha de S. Paulo

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Correlação entre 6-sulfatoximelatonina, distúrbios do sono e citocinas inflamatórias em Transtornos do Espectro do Autismo (TEA)

Pós-graduação em Fonoaudiologia - FFC

Substituição dos grãos secos de milho pela silagem de grãos úmidos de milho para vacas da raça holandesa em lactação

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Efeito da monensina sódica na produção, composição do leite e escore de condição corporal de búfalas Murrah no início da lactação

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Exposição à dieta ocidental durante a gestação, lactação, fase juvenil e susceptibilidade à carcinogênese química do cólon em ratos adultos da linhagem Sprague-Dawley

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Perfil epidemiológico do usuário do serviço de atendimento móvel de urgência por transtornos psiquiátricos na cidade de Bauru

Pós-graduação em Enfermagem (mestrado profissional) - FMB