RIA amb sistema modular per a generar consultes dinàmiques a una base de dades

En aquest projecte s’han unificat les dades de l’empresa Solmania i s’han generat estadístiques i informes a diferents formats mitjançant una aplicació RIA implementada amb Adobe Flex. D’aquesta manera es pot fer un control dels paràmetres clau del negoci per ajudar a la companyia a aconseguir els objectius marcats d’una manera eficient. L’aplicatiu permet analitzar des de diversos punts de vista qualsevol tipus d’informació que genera el negoci i fer-ne comparatives de rendiment.

Explicit methods for Hilbert modular forms

We exhibit algorithms to compute systems of Hecke eigenvalues for spaces of Hilbert modular forms over a totally real field. We provide many explicit examples as well as applications to modularity and Galois representations.

A modular approach for integrative analysis of large-scale gene-expression and drug-response data

High-throughput technologies are now used to generate more than one type of data from the same biological samples. To properly integrate such data, we propose using co-modules, which describe coherent patterns across paired data sets, and conceive several modular methods for their identification. We first test these methods using in silico data, demonstrating that the integrative scheme of our Ping-Pong Algorithm uncovers drug-gene associations more accurately when considering noisy or complex data. Second, we provide an extensive comparative study using the gene-expression and drug-response data from the NCI-60 cell lines. Using information from the DrugBank and the Connectivity Map databases we show that the Ping-Pong Algorithm predicts drug-gene associations significantly better than other methods. Co-modules provide insights into possible mechanisms of action for a wide range of drugs and suggest new targets for therapy

Modular analysis of gene expression data with R.

SUMMARY: Large sets of data, such as expression profiles from many samples, require analytic tools to reduce their complexity. The Iterative Signature Algorithm (ISA) is a biclustering algorithm. It was designed to decompose a large set of data into so-called 'modules'. In the context of gene expression data, these modules consist of subsets of genes that exhibit a coherent expression profile only over a subset of microarray experiments. Genes and arrays may be attributed to multiple modules and the level of required coherence can be varied resulting in different 'resolutions' of the modular mapping. In this short note, we introduce two BioConductor software packages written in GNU R: The isa2 package includes an optimized implementation of the ISA and the eisa package provides a convenient interface to run the ISA, visualize its output and put the biclusters into biological context. Potential users of these packages are all R and BioConductor users dealing with tabular (e.g. gene expression) data. AVAILABILITY: http://www.unil.ch/cbg/ISA CONTACT: sven.bergmann@unil.ch

PICTour : aplicació modular per a la gestió d'imatges geoetiquetades mitjançant serveis en línea independents basada en tecnologia .NET

Aplicació realitzada emprant diverses tecnologies de la plataforma .NET i capaç d'adaptar-se a l'escenari canviant de la web 2.0 i aprofitar les eines que ofereix.

Mutations in the SPARC-Related Modular Calcium-Binding Protein 1 Gene, SMOC1, Cause Waardenburg Anophthalmia Syndrome.

Waardenburg anophthalmia syndrome, also known as microphthalmia with limb anomalies, ophthalmoacromelic syndrome, and anophthalmia-syndactyly, is a rare autosomal-recessive developmental disorder that has been mapped to 10p11.23. Here we show that this disease is heterogeneous by reporting on a consanguineous family, not linked to the 10p11.23 locus, whose two affected children have a homozygous mutation in SMOC1. Knockdown experiments of the zebrafish smoc1 revealed that smoc1 is important in eye development and that it is expressed in many organs, including brain and somites.

Anàlisi i disseny d'un programari de Gestió Remota d'un Parc Modular d'Energia Solar

Anàlisi i disseny d'una aplicació per gestionar de manera remota l'activitat d'un parc d'energia solar fotovoltaica.

Desenvolupament d'un sistema d'adquisició i gestió de dades integrat en una arquitectura modular en xarxa (orientat a la ramaderia de precisió)

Desenvolupament d'un sistema d'adquisició, filtrat, emmagatzetmament i gestió de dades provinents d'un sistema de control de subministrament d'aliment d'una explotació porcina. D'altra banda, l'eina informàtica incorporarà dos bases de dades (bruta i neta) les quals es podran consultar amb un VI específic, tant de manera local com remota amb l'ajuda del webserver de labview, també conté un VI específic de generació d'informes (via internet) que facilita la inspecció de dades. Tots els programes estan implementats en labview i connectats en xarxa.

Sistema modular de presentación de información para la plataforma de web semántica Rhizomer

Aquest projecte es basa en la idea de redefinir la web actual sota el marc de la web semàntica a través de la plataforma rhizomer. Intentant explotar les possibilitats d'indexació semàntica de continguts àudiovisuals. L'objectiu d'aquest treball es generar un sistema de presentació de dades utilitzant els diferents tipus de contingut àudiovisual que ens ofereix el grup de comunicació Segre. Fonamentalment, es desenvoluparan tres sistemes de presentació d'informació diferents: vista geogràfica, vista línia temporal, transcripció i reproducció d'àudio.

Evaluación de la Estructura Modular en la Escuela Superior Universitaria Politécnica. Primera aproximación

En esta comunicación se plasman los resultados obtenidos de la evaluación llevada a cabo respecto la iniciativa tomada por parte del profesorado de la Escuela Superior Politécnica de la Universidad Pompeu Fabra en cuanto a la construcción de una estructura modular sólida y eficaz para la coordinación y gestión de las asignaturas del actual y futuro plan de estudios. Esta nueva estructura de módulos resulta una iniciativa innovadora que, a su vez, potencia y enfatiza la calidad de los estudios. En concreto la comunicación presenta los resultados de la evaluación piloto de uno de los módulos. Estos resultados nos ofrecen información sobre el punto en el que estamos actualmente así como nos orientan hacia nuevasacciones a desarrollar para optimizar la estructura modularsobre la que se basan los nuevos Grados mejorando los procesosque de ella se desprenden.

A systolic array for linear MIMO detection based on an all-swap lattice reduction algorithm

A systolic array to implement lattice-reduction-aided lineardetection is proposed for a MIMO receiver. The lattice reductionalgorithm and the ensuing linear detections are operated in the same array, which can be hardware-efficient. All-swap lattice reduction algorithm (ASLR) is considered for the systolic design.ASLR is a variant of the LLL algorithm, which processes all lattice basis vectors within one iteration. Lattice-reduction-aided linear detection based on ASLR and LLL algorithms have very similarbit-error-rate performance, while ASLR is more time efficient inthe systolic array, especially for systems with a large number ofantennas.

Congruences between modular forms and lowering the level mod l^n

In this article we study the behavior of inertia groups for modularGalois mod l^n representations and in some cases we give a generalizationof Ribet s lowering the level result (cf. [Rib90]).

Computing congruences of modular forms and Galois representations modulo prime powers

This article starts a computational study of congruences of modular forms and modular Galoisrepresentations modulo prime powers. Algorithms are described that compute the maximum integermodulo which two monic coprime integral polynomials have a root in common in a sensethat is defined. These techniques are applied to the study of congruences of modular forms andmodular Galois representations modulo prime powers. Finally, some computational results withimplications on the (non-)liftability of modular forms modulo prime powers and possible generalisationsof level raising are presented.

Sarcomeric M-band alterations as a marker for human dilated cardiomyopathy

Purpose: The M-band is an important cytoskeletal structure in the centre of the sarcomere, believed to cross-link the thick filament lattice. Its main components are three closely related modular proteins from the myomesin gene family: Myomesin, M-protein and myomesin-3. Each muscle is characterized by its unique M-band protein composition, depending on the contractile parameters of a particular fiber. To investigate the role of the M-band in one of the most relevant and clinically increasing cardiac diseases, we analyzed the expression of myomesin proteins in dilated cardiomyopathy (DCM).Methods: In a previous study we analyzed mouse models suffering from DCM, demonstrating that the embryonic heart specific EH-myomesin splicing isoform was up-regulated directly corresponding to the degree of cardiac dysfunction and ventricular dilation. Based on this study, human ventricular and atrial samples (n=32) were obtained during heart surgery after informed consent and approval by an institutional review board. Patients were aged 30-70 years and suffered from dilated cardiomyopathy (DCM;n=13), Hypertrophic Cardiomyopathy (HCM;n=10) or served as controls (n=9). Patients suffering from DCM or HCM were in endstage heart-failure (NYHA III-IV) and either underwent heart transplantation or Left Ventricular Assist Device (LVAD) implantation. Heart samples from patients who underwent valve surgery or congenital heart surgery served as controls. Heart Samples were analyzed using RT-PCR, Western blot, and immunofluorescence.Results: By investigating the expression pattern of myomesins, we found that DCM is accompanied by specific M-band alterations, which were more pronounced in ventricular samples compared to the atrium. Changes in the amounts of different myomesins during DCM occurred in a cell-specific manner, leading to a higher heterogeneity of the cytoskeleton in cardiomyocytes through the myocardial wall with some cells switching completely to an embryonic phenotype.Conclusions: Here we present that the embryonic heart specific EH-myomesin isoform is up-regulated in human DCM. The alterations of the M-band protein composition might be part of a general adaptation of the sarcomeric cytoskeleton to unfavorable working conditions in the failing heart and may modify the mechanical properties of the cardiomyocytes. We suggest that the upregulation of EH-myomesin might play a pivotal role in DCM and might support classical imagingas a novel sarcomeric marker for this disease.

Modular support for developing mobile ad hoc applications

Abstract This PhD thesis addresses the issue of alleviating the burden of developing ad hoc applications. Such applications have the particularity of running on mobile devices, communicating in a peer-to-peer manner and implement some proximity-based semantics. A typical example of such application can be a radar application where users see their avatar as well as the avatars of their friends on a map on their mobile phone. Such application become increasingly popular with the advent of the latest generation of mobile smart phones with their impressive computational power, their peer-to-peer communication capabilities and their location detection technology. Unfortunately, the existing programming support for such applications is limited, hence the need to address this issue in order to alleviate their development burden. This thesis specifically tackles this problem by providing several tools for application development support. First, it provides the location-based publish/subscribe service (LPSS), a communication abstraction, which elegantly captures recurrent communication issues and thus allows to dramatically reduce the code complexity. LPSS is implemented in a modular manner in order to be able to target two different network architectures. One pragmatic implementation is aimed at mainstream infrastructure-based mobile networks, where mobile devices can communicate through fixed antennas. The other fully decentralized implementation targets emerging mobile ad hoc networks (MANETs), where no fixed infrastructure is available and communication can only occur in a peer-to-peer fashion. For each of these architectures, various implementation strategies tailored for different application scenarios that can be parametrized at deployment time. Second, this thesis provides two location-based message diffusion protocols, namely 6Shot broadcast and 6Shot multicast, specifically aimed at MANETs and fine tuned to be used as building blocks for LPSS. Finally this thesis proposes Phomo, a phone motion testing tool that allows to test proximity semantics of ad hoc applications without having to move around with mobile devices. These different developing support tools have been packaged in a coherent middleware framework called Pervaho.