La Inspiració de Van Gogh

La Inspiració de Van Gogh ofereix una reflexió entre les similituds i coincidències de dues societats (la societat de finals del sXIX, i la societat actual) separades pel temps, però unides per la necessitat de trobar una sortida a tanta incomprensió artística i social.

Identification and molecular characterization of Van A-type vancomycin-resistant Enterococcus faecalis in Northeast of Brazil

The isolation of vancomycin resistant enterococci (VRE) in Brazil has rapidly increased, following the world wide tendency. We report in the present study the first isolation of vancomycin resistant Enterococcus faecalis (VRE) in the Northeast of Brazil. The four VRE isolates were characterized for antimicrobial susceptibility, genotypic typing by macro restriction of chromosomal DNA followed by pulsed-field gel electrophoresis and for characterization of the Tn1546-like element and plasmid contents. The isolates showed resistance to multiple antibiotics and a single genotype profile, suggesting the dissemination of a single clone among the patients. Tn1546 associated to genetic elements as plasmids shows the importance of infection control measures to avoid the spreading of glycopetide resistance by conjugative transfer of VanA elements.

Conception mécanique d'un chien robot : GIPO

La conceció de GIPO té com a areferència el gos AIBO, desenvolupat per Sony. L'estudi per a la seva realització comprèn el desenvolupament de la part tecnològica. S'assumeix que la cinemàtica d'AIBO ha estat àmpliament provada i que és òptima.

Blood pressure loci identified with a gene-centric array.

Raised blood pressure (BP) is a major risk factor for cardiovascular disease. Previous studies have identified 47 distinct genetic variants robustly associated with BP, but collectively these explain only a few percent of the heritability for BP phenotypes. To find additional BP loci, we used a bespoke gene-centric array to genotype an independent discovery sample of 25,118 individuals that combined hypertensive case-control and general population samples. We followed up four SNPs associated with BP at our p < 8.56 × 10(-7) study-specific significance threshold and six suggestively associated SNPs in a further 59,349 individuals. We identified and replicated a SNP at LSP1/TNNT3, a SNP at MTHFR-NPPB independent (r(2) = 0.33) of previous reports, and replicated SNPs at AGT and ATP2B1 reported previously. An analysis of combined discovery and follow-up data identified SNPs significantly associated with BP at p < 8.56 × 10(-7) at four further loci (NPR3, HFE, NOS3, and SOX6). The high number of discoveries made with modest genotyping effort can be attributed to using a large-scale yet targeted genotyping array and to the development of a weighting scheme that maximized power when meta-analyzing results from samples ascertained with extreme phenotypes, in combination with results from nonascertained or population samples. Chromatin immunoprecipitation and transcript expression data highlight potential gene regulatory mechanisms at the MTHFR and NOS3 loci. These results provide candidates for further study to help dissect mechanisms affecting BP and highlight the utility of studying SNPs and samples that are independent of those studied previously even when the sample size is smaller than that in previous studies.

4-7-19, stade Pershing, arrivée du marathon [modifié des Jeux interalliés, Jean Vermeulen coupe la ligne d'arrivée, le n°971 Armando Pagliani et le n°1280 Alphonse Van Hoey sont distancés] : [photographie de presse] / [Agence Rol]

Référence bibliographique : Rol, 54715

4-7-19, stade Pershing, départ du marathon [modifié des Jeux interalliés, en tête n°1103 Auguste Broos et n°973 Carlo Speroni suivi par Fred Faller, puis n°846 Clyde Stout, à sa droite Jean Vermeulen, n°730 J. H. Massey, n°1189 Thomas Sinton Hewitt, n°971 Armando Pagliani, n°1280 Alphonse Van Hoey, n°972 Antenore Negri, n°1274 Jules Holsbeeke] : [photographie de presse] / [Agence Rol]

Référence bibliographique : Rol, 54713

[9 phot. de Pise par Van Lint, phot. à Pise, et de Gênes par C. Degoix et A. Noack, phot. à Gênes, don Romanet du Caillaud en 1886]

Donateur : Romanet Du Caillaud, Frédéric (18..-19..?)

[Klaas] Van Nek [coureur cycliste néerlandais participant au meeting de la Toussaint, 1er novembre 1919] : [photographie de presse] / [Agence Rol]

Référence bibliographique : Rol, 56711

Blood pressure loci identified with a gene-centric array.

Raised blood pressure (BP) is a major risk factor for cardiovascular disease. Previous studies have identified 47 distinct genetic variants robustly associated with BP, but collectively these explain only a few percent of the heritability for BP phenotypes. To find additional BP loci, we used a bespoke gene-centric array to genotype an independent discovery sample of 25,118 individuals that combined hypertensive case-control and general population samples. We followed up four SNPs associated with BP at our p < 8.56 × 10(-7) study-specific significance threshold and six suggestively associated SNPs in a further 59,349 individuals. We identified and replicated a SNP at LSP1/TNNT3, a SNP at MTHFR-NPPB independent (r(2) = 0.33) of previous reports, and replicated SNPs at AGT and ATP2B1 reported previously. An analysis of combined discovery and follow-up data identified SNPs significantly associated with BP at p < 8.56 × 10(-7) at four further loci (NPR3, HFE, NOS3, and SOX6). The high number of discoveries made with modest genotyping effort can be attributed to using a large-scale yet targeted genotyping array and to the development of a weighting scheme that maximized power when meta-analyzing results from samples ascertained with extreme phenotypes, in combination with results from nonascertained or population samples. Chromatin immunoprecipitation and transcript expression data highlight potential gene regulatory mechanisms at the MTHFR and NOS3 loci. These results provide candidates for further study to help dissect mechanisms affecting BP and highlight the utility of studying SNPs and samples that are independent of those studied previously even when the sample size is smaller than that in previous studies.

[Klaas] Van Nek [coureur cycliste néerlandais participant au meeting de la Toussaint, 1er novembre 1919] : [photographie de presse] / [Agence Rol]

Référence bibliographique : Rol, 56712