880 resultados para David L. Whitney


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El interés de esta investigación se centra en analizar el rol protagónico que han adquirido las acciones constitucionales en la participación po­tica de la comunidad LGTBI, encaminada a la aprobación del matrimonio igualitario en Colombia, a partir de la promulgación de la Constitución Po­tica de 1991. Para este propósito, el estudio presenta un diagnóstico sobre las falencias y limitaciones que ha presentado la representación po­tica y de los mecanismos de participación ciudadana para solventar las reivindicaciones de las parejas del mismo sexo. En consecuencia, la investigación evidencia de qué manera la sub-representación de los intereses de esta comunidad en el Congreso de la República y la sub-utilización de los mecanismos de participación po­tica causadas por las deficiencias en su diseño e implementación, impulsaron a la población LGTBI y los defensores de sus derechos a canalizar su participación po­tica a través de la presentación de acciones constitucionales.

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Determinar el efecto de la cirugía laparoscópica versus cirugía abierta sobre la supervivencia en el manejo de pacientes del cáncer colorectal.

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El presente estudio de caso consiste en identificar la incidencia del totalitarismo en la configuración de una po­tica exterior aislacionista, tomando los casos del Tercer Reich y la República Democrática Popular de Corea; se trata de inferir si la incidencia de un régimen totalitario en la configuración de una po­tica exterior aislacionista es directa, en tanto que responde al interés nacional del Estado con el fin de implementar reformas y actos que conlleven al aislamiento de la nación de la comunidad internacional. Para dicho efecto, se utilizará el paradigma realista con el que se pretenderán contrastar las diferencias y similitudes entre los casos estudiados. En consecuencia, en la investigación se utilizarán datos de carácter mixto, en tanto su uso cualitativo y cuantitativo.

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Se muestra el trabajo de varios profesores del Departamento de Ciencias Sociales de la Universidad Pablo de Olavide (Sevilla) y la Universidad Nacional Aut??noma de Nicaragua-Managua en un proyecto de cooperaci??n sobre aspectos relacionados con la educaci??n y promoci??n de la salud cuyo fruto ha sido la constituci??n del Observatorio de Calidad de Vida, Desarrollo y Educaci??n para la Salud de la UNAN-Managua.

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Pattern-recognition receptors (PRRs) detect molecular signatures of microbes and initiate immune responses to infection. Prototypical PRRs such as Toll-like receptors (TLRs) signal via a conserved pathway to induce innate response genes. In contrast, the signaling pathways engaged by other classes of putative PRRs remain ill defined. Here, we demonstrate that the β-glucan receptor Dectin-1, a yeast binding C type lectin known to synergize with TLR2 to induce TNFα and IL-12, can also promote synthesis of IL-2 and IL-10 through phosphorylation of the membrane proximal tyrosine in the cytoplasmic domain and recruitment of Syk kinase. syk−/− dendritic cells (DCs) do not make IL-10 or IL-2 upon yeast stimulation but produce IL-12, indicating that the Dectin-1/Syk and Dectin-1/TLR2 pathways can operate independently. These results identify a novel signaling pathway involved in pattern recognition by C type lectins and suggest a potential role for Syk kinase in regulation of innate immunity.

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chiral molecules can modify surfaces in many ways. Long-range chiral structures can be induced by local chirality, which can act as templates stereo-directing other molecules. Such templates are either based on the arrangement of molecules alone or involve reconstruction of the substrate suface. Stereo-direction can also be achieved buy direct local interaction between chiral moleculesx. Even the adsorption of achiral molecules onto achiral surfaces can induce local chirality due to a reduction ofsymmetry in the presence of the surface. Intrinsically chiral metal and oxide surfaces can act as templates for enantioselective adsorption and surface reactions without any surface modification.

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On 16 UK livestock holdings within pastoral landscapes, we investigated the provision of plant and invertebrate resources for farmland birds in spring barley and winter wheat cereal-based whole crop silages as alternatives to maize and grass silages. The benefits of low input barley systems were also investigated; barley fields were subjected to two separate herbicide sub-treatments on a split-field design (high input broad-spectrum or low input narrow spectrum herbicides). The abundance of plant resources and invertebrates was assessed for three growing seasons during summer and winter for each crop type. The study clearly demonstrated the value of spring barley for the provision of plant resources when compared to the other silage cropping systems, whilst invertebrate responses were variable. No differences in plant and invertebrate resources were found between the barley treatments. Throughout the year, forage maize afforded the lowest provision of resources for farmland birds, and because it is likely that maize will continue to be grown in pastoral areas, the value of this habitat needs to be improved if farmland birds are to benefit. To provide plant and invertebrate resources for farmland birds in pastoral landscapes we strongly advocate the growing of spring sown barley whole-crop silage followed by over-wintering stubbles. © 2011 Elsevier B.V. All rights reserved.