Prévention de la maladie de Lyme : facteurs sociaux et priorisation des interventions

La maladie de Lyme est la maladie vectorielle la plus fréquente dans les pays tempérés et est en émergence dans plusieurs régions du monde. Plusieurs stratégies de prévention existent et comprennent des interventions qui visent les individus, comme le port de vêtements protecteurs, et d’autres qui sont implantées au niveau collectif, dont des interventions de contrôle des tiques dans l’environnement. L’efficacité de ces stratégies peut être influencée par divers facteurs, dont des facteurs sociaux tels que les connaissances, les perceptions et les comportements de la population ciblée. Elles peuvent également avoir des impacts parallèles non désirés, par exemple sur l’environnement et l’économie, et ces derniers peuvent s’opposer aux bénéfices des interventions jusqu’à remettre en cause la pertinence de leur mise en œuvre. Aussi, ces facteurs sociaux et les impacts des interventions sont susceptibles de varier selon la population ciblée et en fonction du contexte épidémiologique et social. L’objectif de cette thèse était donc d’étudier les principaux facteurs sociaux et enjeux d’importance à considérer pour évaluer l’efficacité et prioriser des interventions de prévention pour la maladie de Lyme dans deux populations exposées à des contextes différents, notamment en ce qui concerne leur situation épidémiologique, soient au Québec, où l’incidence de la maladie de Lyme est faible mais en émergence, et en Suisse, où elle est élevée et endémique depuis plus de trois décennies. L’approche choisie et le devis général de l’étude sont basés sur deux modèles théoriques principaux, soient le modèle des croyances relatives à la santé et celui de l’aide à la décision multicritère. Dans un premier temps, les facteurs associés à la perception du risque pour la maladie de Lyme, c’est-à-dire l’évaluation cognitive d’une personne face au risque auquel elle fait face, ont été étudiés. Les résultats suggèrent que les facteurs significatifs sont différents dans les deux régions à l’étude. Ensuite, l’impact des connaissances, de l’exposition, et des perceptions sur l’adoption de comportements préventifs individuels et sur l’acceptabilité des interventions de contrôle des tiques (acaricides, modifications de l’habitat, contrôle des cervidés) a été comparé. Les résultats suggèrent que l’impact des facteurs varierait en fonction du type du comportement et des interventions, mais que la perception de l’efficacité est un facteur commun fortement associé à ces deux aspects, et pourrait être un facteur-clé à cibler lors de campagnes de communication. Les résultats montrent également que les enjeux relatifs aux interventions de contrôle des tiques tels que perçus par la population générale seraient communs dans les deux contextes de l’étude, et partagés par les intervenants impliqués dans la prévention de la maladie de Lyme. Finalement, un modèle d’analyse multicritère a été développé à l’aide d’une approche participative pour le contexte du Québec puis adapté pour le contexte suisse et a permis d’évaluer et de prioriser les interventions préventives selon les différentes perspectives des intervenants. Les rangements produits par les modèles au Québec et en Suisse ont priorisé les interventions qui ciblent principalement les populations humaines, devant les interventions de contrôle des tiques. L’application de l’aide à la décision multicritère dans le contexte de la prévention de la maladie de Lyme a permis de développer un modèle décisionnel polyvalent et adaptable à différents contextes, dont la situation épidémiologique. Ces travaux démontrent que cette approche peut intégrer de façon rigoureuse et transparente les multiples perspectives des intervenants et les enjeux de la prévention relatifs à la santé publique, à la santé animale et environnementale, aux impacts sociaux, ainsi qu’aux considérations économiques, opérationnelles et stratégiques. L’utilisation de ces modèles en santé publique favoriserait l’adoption d’une approche « Une seule santé » pour la prévention de la maladie de Lyme et des zoonoses en général. Mots-clés : maladie de Lyme, prévention, facteurs sociaux, perception du risque, comportements préventifs, acceptabilité, priorisation des interventions, contrôle des tiques, aide à la décision multicritère, analyse multicritère, Québec, Suisse, « Une seule santé »

Estado actual del sector estratégico hoteles boutique en Bogotá e identificación de los escenarios de desarrollo alternativos

En el presente trabajo se realizara la aplicación del modelo Análisis Estructural de los Sectores estratégicos y del análisis prospectivo para los hoteles que hacen parte del sector alojamiento en hoteles boutique en Bogotá en un periodo de cinco años. En estos modelos se tiene en cuenta la información financiera, interna y externa de la empresa y aspectos generales relacionados con la economía del sector. La investigación se desarrolló en dos etapas; la primera corresponde al desarrollo del AESE el cual se basa en cuatro herramientas (análisis de hacinamiento cuantitativo y cualitativo, levantamiento del panorama competitivo, análisis estructural de fuerzas del mercado y estudio de competidores) y el análisis prospectivo donde se aplica la metodología MICMAC, MACTOR y SMIC, en las cuales se determinan los escenarios alternativos teniendo presente la influencia que puedan tener los actores del sector y los aspectos sociales, políticos, tecnológicos y económicos en las definición de los escenarios.

The Construction of grammar concepts at secondary school

In this study we make a general research question [1] and two specific ones [2] i [3]: [1] How can we establish a new model for teaching and learning grammar? [2] How metalinguistic knowledge is built within this model? [3] How can we elaborate an analysis model for exploring grammar knowledge?

Relationships between adolescents and parents values and parents answering behaviour

In this paper we set out a confirmatory factor analysis model relating the values adolescents and their parents aspire to for the child’s future. We approach a problem when collecting parents’ answers and analysing paired data from parents and their child: the fact that in some families only one parent answers, while in others both meet to answer together. In order to account for differences between one-parent and two-parent responses we follow a multiple group structural equation modelling approach. Some significant differences emerged between the two and one answering parent groups. We observed only weak relationships between parents’ and children’s values

Measurement Quality in Indicators of Compositions: a Compositional Multitrait-Multimethod Approach

Compositional data, also called multiplicative ipsative data, are common in survey research instruments in areas such as time use, budget expenditure and social networks. Compositional data are usually expressed as proportions of a total, whose sum can only be 1. Owing to their constrained nature, statistical analysis in general, and estimation of measurement quality with a confirmatory factor analysis model for multitrait-multimethod (MTMM) designs in particular are challenging tasks. Compositional data are highly non-normal, as they range within the 0-1 interval. One component can only increase if some other(s) decrease, which results in spurious negative correlations among components which cannot be accounted for by the MTMM model parameters. In this article we show how researchers can use the correlated uniqueness model for MTMM designs in order to evaluate measurement quality of compositional indicators. We suggest using the additive log ratio transformation of the data, discuss several approaches to deal with zero components and explain how the interpretation of MTMM designs di ers from the application to standard unconstrained data. We show an illustration of the method on data of social network composition expressed in percentages of partner, family, friends and other members in which we conclude that the faceto-face collection mode is generally superior to the telephone mode, although primacy e ects are higher in the face-to-face mode. Compositions of strong ties (such as partner) are measured with higher quality than those of weaker ties (such as other network members)

El comportamiento innovador de la empresa industrial. Un modelo de análisis a partir de la encuesta del INE

Los objetivos de la tesis son en primer lugar, el análisis del alcance de los datos disponibles y su grado de validez para proporcionar una visión de la realidad del comportamiento innovador de las empresas españolas. En segundo lugar la definición de un modelo de análisis que pueda ser de interés para la sistematización de los estudios y la posible definición de política de apoyo a la I+D. Finalmente evaluar el potencial que tiene el tratamiento regionalizado de los datos de la encuesta de innovación a partir del estudio del caso de Cataluña y su comparación con los resultados agregados no regionales.

O videoclipe victimless crime e as imagens nos videoclipes

RESUMO: No âmbito do Mestrado em Estudos Cinematográficos da Universidade Lusófona de Humanidades e Tecnologias, propôs-se a concretização de um Projecto-Tese na área do videoclipe. O projecto consiste na produção, realização e edição de um videoclipe. Victimless Crime é o nome da música, criada durante o ano de 2009 e lançada em Maio de 2010, da banda pop lisboeta Soulbizness. O resultado é um videoclipe com a duração de três minutos e vinte e seis segundos, que entende a possibilidade de uma utilização real. Na componente teórica procede-se ao estudo do videoclipe enquanto formato audiovisual e suas especificidades. Segue-se a análise de Victimless Crime, através do Modelo de Análise proposto por Francisco J. G. Tarín, assente em três vectores essenciais: Análise Textual; Análise de Recursos Expressivos e Narrativos; e Interpretação. ABSTRACT: Within the scope of the MFA in Cinematography at the Universidade Lusófona de Humanidades e Tecnologias, a thesis project was proposed in the field of music video. The project consists of producing, directing and editing a music video for the song Victimless Crime, created in 2009 and released in May 2010 by the Lisbon-based pop band Soulbizness. The result is a three minute, twenty-three second music video, complete and ready to be released. The project also includes a theoretical component, consisting of a general review of the music video as an audiovisual format and its characteristics, followed by an analysis of Victimless Crime, as per the Analysis Model proposed by Francisco J. G. Tarín, which is based on three main topics: Textual Analysis; Narrative Analysis and Expressive Language Analysis; and Interpretation.

Design of a biomimetic skin for an octopus-inspired robot - Part II: Development of the skin artefact

In order to develop skin artefact for an octopus-inspired robot arm, which is designed to be able to elongate 60% of its original length, silicone rubber and knitted nylon sheet were selected to manufacture an artificial skin, due to their higher elastic strain and high flexibility. Tensile and scissors cutting tests were conducted to characterise the matrix and reinforcing materials and the skin artefact. Material properties of the individual and the composite materials were compared with the measured properties of real octopus skin presented in Part I. The Young’s modulus of the skin should be below 20 MPa and the elastic strain range should be over 60%. The fracture toughness should be at least 0.9 kJ·m−2. Tubes made of the skin artefact filled with liquid were tested to study volume change under deformation. Finite element analysis model was developed to simulate the material and arm structure under tensile loading. Results show that the skin artefact developed has similar mechanical properties as the real octopus skin and satisfies all the design specifications of the OCTOPUS robot.

Output sustainability to exogenous and endogenous shocks: evidence from emerging economies

This paper studies the impact of exogenous and endogenous shocks (exogenous shock is used interchangeably with external shock; endogenous shock is used interchangeably with domestic shock) on output fluctuations in post-communist countries during the 2000s. The first part presents the analytical framework and formulates a research hypothesis. The second part presents vector autoregressive estimation and analysis model proposed by Pesaran (2004) and Pesaran and Smith (2006) that relates bank real lending, the cyclical component of output and spreads and accounts for cross-sectional dependence (CD) across the countries. Impulse response functions show that exogenous positive shock lead to a drop in output sustainability for 9 over 12 Central Eastern European countries and Russia, when the endogenous shock is mild and ambiguous. Moreover, the effect of exogenous shock is more significant during the crises. Variance decompositions show that exogenous shock in the aftermath of crisis had a substantial impact on economic activity of emerging economies.

A reduction of CETP activity, not an increase, is associated with modestly impaired postprandial lipemia and increased HDL-Cholesterol in adult asymptomatic women

Background: The relationship between CETP and postprandial hyperlipemia is still unclear. We verified the effects of varying activities of plasma CETP on postprandial lipemia and precocious atherosclerosis in asymptomatic adult women. Methods: Twenty-eight women, selected from a healthy population sample (n = 148) were classified according to three CETP levels, all statistically different: CETP deficiency (CETPd <= 4.5%, n = 8), high activity (CETPi >= 23.8, n = 6) and controls (CTL, CETP >= 4.6% and <= 23.7%, n = 14). After a 12 h fast they underwent an oral fat tolerance test (40 g of fat/m(2) of body surface area) for 8 hours. TG, TG-rich-lipoproteins (TRL), cholesterol and TRL-TG measurements (AUC, AUIC, AR, RR and late peaks) and comparisons were performed on all time points. Lipases and phospholipids transfer protein (PLTP) were determined. Correlation between carotid atherosclerosis (c-IMT) and postprandial parameters was determined. CETP TaqIB and I405V and ApoE-epsilon 3/epsilon 2/epsilon 4 polymorphisms were examined. To elucidate the regulation of increased lipemia in CETPd a multiple linear regression analysis was performed. Results: In the CETPi and CTL groups, CETP activity was respectively 9 and 5.3 higher compared to the CETPd group. Concentrations of all HDL fractions and ApoA-I were higher in the CETPd group and clearance was delayed, as demonstrated by modified lipemia parameters (AUC, AUIC, RR, AR and late peaks and meal response patterns). LPL or HL deficiencies were not observed. No genetic determinants of CETP deficiency or of postprandial lipemia were found. Correlations with c-IMT in the CETPd group indicated postprandial pro-atherogenic associations. In CETPd the regression multivariate analysis (model A) showed that CETP was largely and negatively predicted by VLDL-C lipemia (R(2) = 92%) and much less by TG, LDL-C, ApoAI, phospholipids and non-HDL-C. CETP (model B) influenced mainly the increment in ApoB-100 containing lipoproteins (R(2) = 85% negatively) and phospholipids (R(2) = 13%), at the 6(th)h point. Conclusion: The moderate CETP deficiency phenotype included a paradoxically high HDL-C and its sub fractions (as earlier described), positive associations with c-IMT, a postprandial VLDL-C increment predicting negatively CETP activity and CETP activity regulating inversely the increment in ApoB100-containing lipoproteins. We hypothesize that the enrichment of TG content in triglyceride-rich ApoB-containing lipoproteins and in TG rich remnants increases lipoproteins` competition to active lipolysis sites, reducing their catabolism and resulting on postprandial lipemia with atherogenic consequences.

Estilo de gestão na elaboração de política de assistência social : a visão do conselho municipal de assistência social de Porto Alegre (RS)

Esta pesquisa avalia o estilo de gestão do CMAS/POA na elaboração da política de assistência social do município, na visão dos seus próprios integrantes (conselheiros). Baseiase no modelo de análise de estilo de gestão estruturado por Rensis Likert, aplicado às condições e contexto de um conselho de assistência social. Todos os 35 conselheiros municipais responderam a um questionário de levantamento de dados quantitativos, utilizando uma escala tipo Likert, com respostas no intervalo de 1 a 4, correspondendo aos estilos de gestão: autoritário-forte, autoritário-benévolo, participativoconsultivo e participativo-grupal. As questões abrangem aspectos relativos às dimensões ou temas: processos de liderança utilizados, natureza das forças motivacionais, do processo de comunicação, do processo de influência e interação, do processo decisório, do sistema de metas e diretrizes, do processo de controle e metas de desempenho e treinamento. Os resultados evidenciam que o estilo de gestão do CMAS/POA é o participativoconsultivo. A análise das variáveis causais permite sugerir diversas ações para tornar o estilo de gestão participativo grupal.

Estilo de gestão em conselhos municipais e sua influência numa administração pública municipal : caso do Conselho Municipal de Educação de Dom Pedrito - RS

Esse estudo visa identificar o estilo de gestão do Conselho Municipal de Educação de Dom Pedrito, de acordo com a percepção de seus próprios componentes, e qual a influência das ações deste Conselho na Administração Pública Municipal de Dom Pedrito. A pesquisa está alicerçada em dois momentos importantes: o primeiro se constitui numa pesquisa quantitativa aplicada às (9) nove conselheiras titulares, usando um questionário baseado no modelo de análise de Likert; o segundo se constitui numa pesquisa qualitativa, com entrevistas semi-estruturadas, para analisar as variáveis que envolvem a relação Conselho Municipal de Educação (CME), Secretaria Municipal de Educação (SME) e Poder decisório Municipal (Prefeito). Os resultados obtidos evidenciam que o estilo de gestão do Conselho Municipal de Educação é o participativo-consultivo. Por outro lado, a pesquisa qualitativa mostra a importância da existência e da atuação do Conselho Municipal de Educação, que tem de trabalhar em consonância com os órgãos com os quais se relaciona e interage. Conclui-se que o Conselho Municipal de Educação é importante para garantir transparência, fundamentar as decisões do executivo municipal e espelhar a vontade da comunidade, além de apontar potencialidades existentes.

Dinâmica de institucionalização de práticas sociais: estudo da responsabilidade social no campo das organizações bancárias

The scope of this theses is to understand the dynamics of the institutionalization of Corporate Social Responsibility (CSR) within the Field of Banking Organizations in Brazil. Using the social analysis model put forward by Boltanski and Chiapello (1999) and reverting to the conceptual basis of the institutional approach and using Bourdieu¿s notion of interest (1996), we arrive at an analytical model that enabled us to assess CSR as part of a movement of displacement of capitalism. The theory we propose here is that with the institutionalization of CSR, actions are justified in terms of the common good, being legitimized by structural confirmations and arrangements and, at the same time, heeding the inherent interests of the Field. The means used for comprehension of the dynamics of the institutionalization of CSR were: (1) the analysis of the construction of the phenomenon of CSR, which enabled us to identify critical factors and events, leaders in Brazil and associated ratification of the institutionalization of this social practice; (2) the description of the Field of Banking Organizations and the identification of the elements of its CSR in History, which are essential steps for understanding the justifications for insertion of the Field in the movement towards CSR; (3) the identification of key players in the institutionalization of the social practice within the Field, as well as the categorization of practical actions considered socially responsible to be found in the organizations researched, analyzing them in terms of justifications and interests; (4) the analysis of the dissemination and sedimentation of structural arrangements linked to CSR in the organizations of the Field, such as specific areas created to deal with CSR, social reports and organizational websites. The field research assessed some 30 organizations and included documentary analysis and interviews. We noted that, from being a marginal and isolated action, over the course of the past decade CSR has become a structured action in banking organizations, while at the same time becoming transformed into a social value, capable of contributing to the legitimacy of the Field. In this respect, research showed that retail banks are those that are inserted in the movement towards CSR, which ratifies the thesis of the phenomenon as displacement of capitalism.

Democratização da gestão pública: a municipalização da saúde nos municípios brasileiros de pequeno e médio porte

The present study analyses the relationship between Democracy and Local Government concerning Public Health Policy of small and medium Brazilian municipalities (with less than 50 thousand inhabitants). The management of the Department of Health in these municipalities was analysed to observe the democratization of public health through the main innovations on the way of management and on the health assistance. A comparison between the answers of the Health Department Managers of municipalities with less than 50 thousand inhabitants and the ones with more than 50 thousand inhabitants (collected in another research) was made as well as the elaboration of a factorial analysis model which verifies the relationship between Manage Profile, Innovating Management and Municipality Demographic Size. Innovating features are found in the small and medium municipalities although in a weaker degree than in the big ones. The relationship observed between the Demographic Extent and Innovating Management as well as the first and Manager Profile are not as strong as the Manager Profile and Innovating Management, concluding that the small dimension of a municipality is not an impediment to a more democratic health management.

Correlação entre qualidade de ensino e os investimentos financeiros

O senso comum vincula a falta de qualidade do ensino público à insuficiência de recursos financeiros disponíveis. Também no meio acadêmico, pesquisadores alegam a inexistência de recursos suficientes para que seja fornecida uma educação de qualidade, enquanto outros acadêmicos defendem que, apesar de poucos recursos disponíveis, o maior problema é a falta de eficiência dos investimentos financeiros pelo gestor público. Nesta pesquisa foram realizadas duas análises: a primeira correlacionando a qualidade do ensino aos investimentos financeiros sob uma perspectiva quantitativa destes investimentos, utilizando um modelo de análise bivariável; enquanto a segunda análise correlaciona a qualidade do ensino aos investimentos financeiros sob uma perspectiva qualitativa destes investimentos, utilizando a alocação dos recursos financeiros para qualificá-los. A análise dos resultados desta pesquisa comprova que os investimentos financeiros no ensino não devem ser vinculados somente em função da quantidade dos investimentos financeiros. Os investimentos financeiros podem ser alocados em diversos tipos de despesas no universo educacional, tais como: remuneração de magistério, alimentação e transporte escolar, distribuição de uniformes, materiais didáticos, infra-estrutura, dentre outros. Algumas dessas despesas agregam maior valor ao ensino que outras. Assim, a prioridade dos programas e políticas educacionais municipais está diretamente ligada à qualidade do ensino municipal.