Voyage into the Golden Screen

Digitoitu 19. 9. 2008.

The factorial structure of the 41-item version of the Screen for Child Anxiety Related Emotional Disorders (SCARED) in a Spanish population of 8 to 12 years-old

On this instrumental study we intend to analyse the factorial structure of the Screen for Child Anxiety Related Emotional Disorders (SCARED) in a Spanish sample using exploratory and confirmatory factorial analysis. As a second objective we intend to develop a short form of it for rapid screening and, finally, to analyze the reliabilities of both questionnaires. The SCARED was administered to a community sample of 1,508 children aged between 8 and 12 years. The sample was randomly split using half for the exploratory analysis and the other half for the confirmatory study. Furthermore a reduced version of the SCARED was developed using the SchmidLeiman procedure. Exploratory Factor Analysis yielded a four factor structure comprised of Somatic/panic, Generalized anxiety, Separation anxiety and Social phobia factors This structure was confirmed using Confirmatory Factor Analysis. The four factors, the full scale and the short scale showed good reliabilities. The results obtained seem to indicate that the Spanish version of the SCARED has good internal consistency, and along with other recent results, has a structure of four related factors that replicates the dimensions proposed for anxiety disorders by the DSM-IV-TR

Del papel a la pantalla y del aula a la nube: ideas para dinamizar la expresión escrita en secundaria = From paper to the screen and from the classroom to the cloud: ideas to energise written expression at secondary level

The spread of sociocultural focuses and critical literacy studies, which offer an holistic perspective on communicative skills, has reached our country at a time when the commonest environment for writing is the internet, and information technologies have transformed writing with new channels, genres, forms of preparation and languages. Thanks to these changes, educational programmes now include new concepts of literacy related to knowledge and the use of digital environments. This paper explores the impact of introducing these new communicative environments to teaching written expression at secondary level and puts forward some ideas to link learning how to write to present communicative contexts and established practices. Without forgetting the achievements of recent decades, we need to bring about a series of changes to bring new learned writing practices to class and leave behind others we had championed as necessary when the goal was to move beyond exclusively linguistic or grammatical approaches

Reducing Manufacturing Costs of the Screen Dryer’s Hot Section by Design

In this thesis, the purpose was to find the cost distribution of the screen dryer and the largest cost factors. The hot section of the screen dryer was revealed as the biggest cost factor, so composing new cost efficient solutions were directed to it. DFMA (Design for Manufacture and Assembly) was chosen to help the design process. DFMA is a product design strategy developed for taking manufacturing and assembly costs into account at the early stages of the design process. In the theory part of the thesis, other methods of economical design and tools needed for estimating manufacturing costs are introduced. In the empirical part, the hot section of the screen dryer was divided into sub-assemblies and their manufacturing costs were estimated. The design propositions were directed to the self-manufactured assemblies and parts. The new manufacturing costs were calculated for the developed propositions. Lastly, the most cost efficient solutions were summarized. The savings on the self-manufactured assemblies were about 40 %, which was about 13 % of the combined total costs of the hot section.

Chemical Biology Screen for Prostate Cancer Therapeutics

Prostate cancer initially responds to hormone-based therapeutics such as anti-androgen treatment or chemotherapeutics but eventually becomes resistant. Novel treatment options are therefore urgently needed. This thesis study applied a high-throughput screen of 4910 known drugs and drug-like small molecules to identify compounds that selectively inhibit growth of prostate cancer cells. In addition, the mechanisms underlying the cellular sensitivity to potent cancer selective compounds were addressed. Surprisingly, many of the compounds currently used in the clinics or studied in clinical trials were not cancer-selective. Only four drugs, aldehyde dehydrogenase inhibitor disulfiram (Antabus), antibiotic ionophore monensin, histone deacetylase inhibitor tricostatin A and fungicide thiram inhibited prostate cancer cell growth at nanomolar concentrations without major effects on non-malignant prostate epithelial cells. Disulfiram, monensin and a structurally similar compound to monensin, salinomycin, induced oxidative stress and inhibited aldehyde dehydrogenase activity. Moreover, monensin and salinomycin reduced androgen receptor signalling and steroidogenesis, enforced cell differentiation and reduced the overall levels of cancer stem cells. Taken together, novel and potentially prostate cancer-selective therapeutic agents were identified in this study, including the description of a multitude of intoxicating mechanisms such as those relating to oxidative stress. The results provide novel insights into prostate cancer biology and exemplify useful means of considering novel approaches to cancer treatment.

Metodologia de Estudo de Dieta Total no Estado de São Paulo para estimativa de ingestão dietética de elementos tóxicos e essenciais: a elaboração da Cesta de Mercado (Market Basket)

O objetivo do estudo foi elaborar a Cesta de Mercado para a realização de Estudos de Dieta Total (EDT) para avaliação de ingestão dietética de elementos tóxicos e essenciais no Estado de São Paulo. A fonte de dados foi a pesquisa de consumo nacional domiciliar atualizada, Pesquisa de Orçamentos Familiares (POF) 2002-2003, do Instituto Brasileiro de Geografia e Estatística (IBGE). Para estimar o consumo de alimentos pela população estudada, os dados de aquisição alimentar utilizados foram pertinentes ao Estado de São Paulo. A Cesta de Mercado inicialmente foi formulada com os dados disponíveis das publicações do IBGE, e para detalhamento dos alimentos foram pesquisados os seus Micro dados, resultando numa Cesta de Mercado com 71 alimentos, que corresponde a 72% do peso dos alimentos da população do Estado de São Paulo, segundo a POF. Como abordagem sugerida pelos EDT já realizados em outros países, os alimentos foram agrupados em 30 compostos, que serão posteriormente analisados para determinar o seu conteúdo dos elementos essenciais e tóxicos.

Athlétic : organe officiel de la Fédération française d'athlétisme et de basket-ball

1933/12 (A2,N84).

Athlétic : organe officiel de la Fédération française d'athlétisme et de basket-ball

1933/01 (A2,N37).

Athlétic : organe officiel de la Fédération française d'athlétisme et de basket-ball

1933/10 (A2,N76).

Athlétic : organe officiel de la Fédération française d'athlétisme et de basket-ball

1932/12/08 (A1,N32).

Athlétic : organe officiel de la Fédération française d'athlétisme et de basket-ball

1932/07/28 (A1,N13).

Athlétic : organe officiel de la Fédération française d'athlétisme et de basket-ball

1932/10/13 (A1,N24).

Athlétic : organe officiel de la Fédération française d'athlétisme et de basket-ball

1934/03/29 (N5).