Desenvolupament d'un widget FlexViewer per Meteoclimatic

En la totalitat del següent document es detalla el procés dut a terme per a la realització d'un sistema d'informació geogràfica (SIG) en relació a la creació d'un widget amb dades meteorològiques a temps real de Meteoclimatic, utilitzant els productes d'Adobe Flash Builder 4.5 i l'API ArcGIS for Flex (que ens permetrà implementar mapes ESRI dins aquest entorn).

Redefinición del interfaz del Centro de Tráfico Centralizado (CTC) de una explotación ferroviaria

En aquest projecte, es mira de reflectir la necessitat d'utilitzar l'enginyeria i la facilitat d'ús per millorar els sistemes de control en temps real que es fan servir avui dia per a controlar processos crítics.

Sistemes de pagament

Al llarg d'aquest treball es desenvolupa un sistema de micropagament basat en un model client - servidor en què el procés d'intercanvi de dades no necessita ser validat en temps real. El client té una cartera on guarda les monedes de què disposa per a fer les compres, i el servidor demana les monedes abans de fer la transferència del producte adquirit; aquestes monedes són guardades pel servidor i al final del dia es fa la conversió a diners.

Librería para análisis dinámico de programas

Este proyecto consiste en el diseño y desarrollo de una librería de interposición de propósito general en lenguaje C para la plataforma GNU/Linux, así como de un prototipo para demostrar la utilidad de la librería. La idea es que dicha librería se pueda utilizar en aquellos programas que necesiten modificar el comportamiento de otros programas, interceptar las llamadas al sistema y, en un sentido amplio, obtener información sobre las actividades de otros procesos en tiempo real. Por tanto, se tratará de diseñar un marco adecuado para futuros proyectos relacionados con el análisis de software. Se pretende también realizar un estudio que permita conocer las diferentes técnicas de depuración, diagnóstico y optimización de aplicaciones, y el software libre existente para realizar dichas tareas.

Web de control de tráfico marítimo

El proyecto Web de Control de Tráfico Marítimo (WCTM) un proyecto Web que va a gestionar información útil para el Control del Tráfico Marítimo de una determinada zona del mundo. Usa el concepto de arquitectura SOA, una arquitectura que se basa en los servicios Web, proporciona en tiempo real información sobre los buques usando los mapas de Google.

mpiGL : un projecte d'utilització del programari lliure en la visualització gràfica en xarxes de càlcul científic

S'analitzen les problemàtiques relacionades amb la presentació d'informació gràfica en temps real durant un càlcul paral·lel o col·laboratiu en un entorn distribuït, i es fa una proposta de toolkit obert que estén el llenguatge OpenGL per la seva resolució.

Alterations of specific biomarkers of metabolic pathways in vascular tree from patients with Type 2 diabetes.

The aims of this study were to check whether different biomarkers of inflammatory, apoptotic, immunological or lipid pathways had altered their expression in the occluded popliteal artery (OPA) compared with the internal mammary artery (IMA) and femoral vein (FV) and to examine whether glycemic control influenced the expression of these genes. The study included 20 patients with advanced atherosclerosis and type 2 diabetes mellitus, 15 of whom had peripheral arterial occlusive disease (PAOD), from whom samples of OPA and FV were collected. PAOD patients were classified based on their HbA1c as well (HbA1c ≤ 6.5) or poorly (HbA1c > 6.5) controlled patients. Controls for arteries without atherosclerosis comprised 5 IMA from patients with ischemic cardiomyopathy (ICM). mRNA, protein expression and histological studies were analyzed in IMA, OPA and FV. After analyzing 46 genes, OPA showed higher expression levels than IMA or FV for genes involved in thrombosis (F3), apoptosis (MMP2, MMP9, TIMP1 and TIM3), lipid metabolism (LRP1 and NDUFA), immune response (TLR2) and monocytes adhesion (CD83). Remarkably, MMP-9 expression was lower in OPA from well-controlled patients. In FV from diabetic patients with HbA1c ≤6.5, gene expression levels of BCL2, CDKN1A, COX2, NDUFA and SREBP2 were higher than in FV from those with HbA1c >6.5. The atherosclerotic process in OPA from diabetic patients was associated with high expression levels of inflammatory, lipid metabolism and apoptotic biomarkers. The degree of glycemic control was associated with gene expression markers of apoptosis, lipid metabolism and antioxidants in FV. However, the effect of glycemic control on pro-atherosclerotic gene expression was very low in arteries with established atherosclerosis.

FABP4 Dynamics in Obesity: Discrepancies in Adipose Tissue and Liver Expression Regarding Circulating Plasma Levels.

BACKGROUND FABP4 is predominantly expressed in adipose tissue, and its circulating levels are linked with obesity and a poor atherogenic profile. OBJECTIVE In patients with a wide BMI range, we analyze FABP4 expression in adipose and hepatic tissues in the settings of obesity and insulin resistance. Associations between FABP4 expression in adipose tissue and the FABP4 plasma level as well as the main adipogenic and lipolytic genes expressed in adipose tissue were also analyzed. METHODS The expression of several lipogenic, lipolytic, PPAR family and FABP family genes was analyzed by real time PCR. FABP4 protein expression in total adipose tissues and its fractions were determined by western blot. RESULTS In obesity FABP4 expression was down-regulated (at both mRNA and protein levels), with its levels mainly predicted by ATGL and inversely by the HOMA-IR index. The BMI appeared as the only determinant of the FABP4 variation in both adipose tissue depots. FABP4 plasma levels showed a significant progressive increase according to BMI but no association was detected between FABP4 circulating levels and SAT or VAT FABP4 gene expression. The gene expression of FABP1, FABP4 and FABP5 in hepatic tissue was significantly higher in tissue from the obese IR patients compared to the non-IR group. CONCLUSION The inverse pattern in FABP4 expression between adipose and hepatic tissue observed in morbid obese patients, regarding the IR context, suggests that both tissues may act in a balanced manner. These differences may help us to understand the discrepancies between circulating plasma levels and adipose tissue expression in obesity.

Laboratory detection of respiratory viruses by automated techniques.

Advances in clinical virology for detecting respiratory viruses have been focused on nucleic acids amplification techniques, which have converted in the reference method for the diagnosis of acute respiratory infections of viral aetiology. Improvements of current commercial molecular assays to reduce hands-on-time rely on two strategies, a stepwise automation (semi-automation) and the complete automation of the whole procedure. Contributions to the former strategy have been the use of automated nucleic acids extractors, multiplex PCR, real-time PCR and/or DNA arrays for detection of amplicons. Commercial fully-automated molecular systems are now available for the detection of respiratory viruses. Some of them could convert in point-of-care methods substituting antigen tests for detection of respiratory syncytial virus and influenza A and B viruses. This article describes laboratory methods for detection of respiratory viruses. A cost-effective and rational diagnostic algorithm is proposed, considering technical aspects of the available assays, infrastructure possibilities of each laboratory and clinic-epidemiologic factors of the infection.

Introduction of an automated system for the diagnosis and quantification of hepatitis B and hepatitis C viruses.

Hepatitis B virus (HBV) and Hepatitis C virus (HCV) infections pose major public health problems because of their prevalence worldwide. Consequently, screening for these infections is an important part of routine laboratory activity. Serological and molecular markers are key elements in diagnosis, prognosis and treatment monitoring for HBV and HCV infections. Today, automated chemiluminescence immunoassay (CLIA) analyzers are widely used for virological diagnosis, particularly in high-volume clinical laboratories. Molecular biology techniques are routinely used to detect and quantify viral genomes as well as to analyze their sequence; in order to determine their genotype and detect resistance to antiviral drugs. Real-time PCR, which provides high sensitivity and a broad dynamic range, has gradually replaced other signal and target amplification technologies for the quantification and detection of nucleic acid. The next-generation DNA sequencing techniques are still restricted to research laboratories.The serological and molecular marker methods available for HBV and HCV are discussed in this article, along with their utility and limitations for use in Chronic Hepatitis B (CHB) diagnosis and monitoring.

WheresApp : Aplicació per a Android

WheresApp és una aplicació per a Android que permet veure la posició, en temps real, dels contactes d'un usuari. Aquesta aplicació incorpora la característica de "bombolla de protecció", la qual permet definir la distància mínima amb la qual un usuari vol ser "trobat" pels seus contactes.

Differences in osteogenic and apoptotic genes between osteoporotic and osteoarthritic patients.

BACKGROUND Osteoporosis is a metabolic disorder characterized by a reduction in bone mass and deterioration in the microarchitectural structure of the bone, leading to a higher risk for spontaneous and fragility fractures.The main aim was to study the differences between human bone from osteoporotic and osteoarthritic patients about gene expression (osteogenesis and apoptosis), bone mineral density, microstructural and biomechanic parameters. METHODS We analyzed data from 12 subjects: 6 with osteoporotic hip fracture (OP) and 6 with hip osteoarthritis (OA), as the control group. All subjects underwent medical history, analytical determinations, densitometry, histomorphometric and biochemical study. The expression of 86 genes of osteogenesis and 86 genes of apoptosis was studied in pool of bone samples from patients with OP and OA by PCR array. RESULTS We observed that most of the genes of apoptosis and osteogenesis show a decrease in gene expression in the osteoporotic group in comparison with the osteoarthritic group. The histomorphometric study shows a lower bone quality in the group of patients with hip fractures compared to the osteoarthritic group. CONCLUSIONS The bone tissue of osteoporotic fracture patients is more fragile than the bone of OA patients. Our results showed an osteoporotic bone with a lower capacities for differentiation and osteoblastic activity as well as a lower rate of apoptosis than osteoarthritic bone. These results are related with structural and biochemical parameters.

Implantación de SAP R/3 en empresa comercial

El propósito del presente proyecto es el estudio de la implantación de un ERP (Enterprise Resource Planning) en una empresa del sector comercial que se dedica a la venta de perfumes y tiene diferentes comercios repartidos por todo el territorio nacional. Con esta aplicación se quiere controlar en tiempo real el stock y las ventas, y por otro lado se quiere automatizar el proceso de implantación de campañas de marketing y que los comercios apliquen los mismos precios en determinado momento.

Sistema de seguimiento de envíos

Con este proyecto se desarrolla una aplicación donde se podrá ver el estado actual de cada uno de los envíos de una empresa de mensajería. Se gestionarán los datos principales de los envíos en la oficina central y se actualizarán los estados de los envíos en tiempo real con dispositivos smartphones que llevarán los repartidores de la empresa.

Resource management research in Passive Optical Networks (PON)

Next Generation Access Networks (NGAN) are the new step forward to deliver broadband services and to facilitate the integration of different technologies. It is plausible to assume that, from a technological standpoint, the Future Internet will be composed of long-range high-speed optical networks; a number of wireless networks at the edge; and, in between, several access technologies, among which, the Passive Optical Networks (xPON) are very likely to succeed, due to their simplicity, low-cost, and increased bandwidth. Among the different PON technologies, the Ethernet-PON (EPON) is the most promising alternative to satisfy operator and user needs, due to its cost, flexibility and interoperability with other technologies. One of the most interesting challenges in such technologies relates to the scheduling and allocation of resources in the upstream (shared) channel. The aim of this research project is to study and evaluate current contributions and propose new efficient solutions to address the resource allocation issues in Next Generation EPON (NG-EPON). Key issues in this context are future end-user needs, integrated quality of service (QoS) support and optimized service provisioning for real time and elastic flows. This project will unveil research opportunities, issue recommendations and propose novel mechanisms associated with the convergence within heterogeneous access networks and will thus serve as a basis for long-term research projects in this direction. The project has served as a platform for the generation of new concepts and solutions that were published in national and international conferences, scientific journals and also in book chapter. We expect some more research publications in addition to the ones mentioned to be generated in a few months.